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    • 3. 发明授权
    • Video test strip reader and method for evaluating test strips
    • 视频测试条读取器和评估测试条的方法
    • US5408535A
    • 1995-04-18
    • US117782
    • 1993-09-07
    • Willis E. Howard, IIIDijia HuangRobert W. RogersGerald H. ShafferMark A. Yoder
    • Willis E. Howard, IIIDijia HuangRobert W. RogersGerald H. ShafferMark A. Yoder
    • G01N33/52G01N21/78G01N21/84G01N21/86G01N31/22G01N35/00H04N7/18G06K9/00G01N21/01
    • G01N21/8483G01N2021/177G01N2035/00108Y10T436/11
    • A video test strip reader uses a video imager or camera for viewing a viewing field containing reagent test strips each having test pads reacted with a specimen containing constituents of interest. The video imager produces an analog signal representing an image of the viewing field. An image handler coupled to the video imager converts or digitizes the analog signal into a digital signal representing the image and stores the image in the form of an array of pixels representing the image. Each pixel contains color information broken down into red, green or blue (RGB). A processor coupled to the image handler analyzes the array of pixels, determines the location and orientation of a test strip, identifies the test areas on the test strip, measures the corresponding test areas on the strip at the proper times and calculates the test results, such as the concentration of the constituents of interest in the specimen or other measurable properties of the specimen such as color or specific gravity, etc. Accordingly, the video test strip reader can simultaneously locate, color analyze and time track multiple test strips on the viewing field.
    • 视频测试读取器使用视频成像器或相机来观看包含试剂测试条的观察区,每个测试条具有与包含感兴趣的成分的样本反应的测试垫。 视频成像器产生表示视野的图像的模拟信号。 耦合到视频成像器的图像处理器将模拟信号转换或数字化为表示图像的数字信号,并以表示图像的像素阵列的形式存储图像。 每个像素包含分为红色,绿色或蓝色(RGB)的颜色信息。 耦合到图像处理器的处理器分析像素阵列,确定测试条的位置和方位,识别测试条上的测试区域,在适当的时间测量条带上相应的测试区域并计算测试结果, 例如样品中感兴趣的组分的浓度或样品的其他可测量性质如颜色或比重等。因此,视频测试条读取器可以同时定位,颜色分析和时间跟踪多个测试条在观看 领域。
    • 6. 发明授权
    • Spectrophotometric apparatus with multiple readheads
    • 具有多个读数头的分光光度计
    • US06180409B2
    • 2001-01-30
    • US09170270
    • 1998-10-13
    • Willis E. Howard, IIIGary E. RehmGerald H. Shaffer
    • Willis E. Howard, IIIGary E. RehmGerald H. Shaffer
    • G01N2113
    • G01N35/00029G01N21/8483G01N2035/00118Y10T436/112499Y10T436/113332
    • An apparatus for inspecting a reagent strip (14) having a fluid sample disposed thereon is provided with a conveyor system (80) adapted to move the reagent strip (14) from a first reagent strip inspection location to a second reagent strip inspection location, a first readhead (60) associated with the first reagent strip inspection location, and a second readhead (62) associated with the second reagent strip inspection location. Each of the readheads (60, 62) has a light source (64, 68) and a light detector (66, 70) associated therewith, each light source (64, 68) being adapted to illuminate the reagent strip (14) at one of the reagent strip inspection locations and each light detector (66, 70) being adapted to detect light from the reagent strip (14) when the reagent strip (14) is disposed at one of the reagent strip inspection locations.
    • 用于检查其上设置有流体样品的试剂条(14)的装置设置有适于将试剂条(14)从第一试剂条检查位置移动到第二试剂条检查位置的输送系统(80), 与第一试剂条检查位置相关联的第一读数头(60)和与第二试剂条检查位置相关联的第二读数头(62)。 每个读取头(60,62)具有光源(64,68)和与其相关联的光检测器(66,70),每个光源(64,68)适于在一个位置上照亮试剂条(14) 的试剂条检查位置和每个光检测器(66,70)适于在试剂条(14)设置在一个试剂条检查位置时检测来自试剂条(14)的光。
    • 7. 发明授权
    • Device and method for measuring light diffusely reflected from a
nonuniform specimen
    • 用于测量从不均匀样品漫反射的光的装置和方法
    • US4755058A
    • 1988-07-05
    • US866730
    • 1986-05-27
    • Gerald H. Shaffer
    • Gerald H. Shaffer
    • G01N21/47G01N21/86G01N21/31
    • G01N21/8483G01N21/474G01N2021/478G01N2201/06146G01N2201/0621G01N2201/0696
    • A device for making accurate, reproducible light reflectance measurements on an optically nonuniform specimen comprises means for holding the specimen in a fixed position. In one embodiment the specimen is illuminated by light sources that are arranged at acute angles relative to the specimen and (360.degree./N.+-.1.degree.) apart in azimuth, where N=the total number of light sources. The light sources are sequentially energized and deenergized to illuminate the specimen. A light detector receives light reflecting from the surface and generates an electrical signal, which is subsequently processed. In another embodiment the light sources are arranged in pairs in which the two light sources in a pair are simultaneously energized and deenergized and the pairs are sequentially energized and deenergized. A method for measuring reflected light is also provided. The device and method are useful for making biochemical assays with reagent test strips by measuring the tone of coloration of the strips after treatment with a target substance being examined.
    • 用于在光学不均匀样品上进行准确,可再现的光反射测量的装置包括用于将样品保持在固定位置的装置。 在一个实施例中,样品被相对于试样以锐角排列并且在方位角(360°/ N +/- 1°)分开的光源照射,其中N =光源的总数。 光源依次通电并断电以照射样品。 光检测器接收从表面反射的光并产生随后处理的电信号。 在另一个实施例中,光源成对地布置,其中一对中的两个光源同时通电并断电,并且对依次通电并断电。 还提供了一种用于测量反射光的方法。 该装置和方法可用于通过用待检测的目标物质测量处理后条带的着色色调来对试剂测试条进行生化测定。