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1. 发明授权

US5103817A Automatic dye dispersant for endotracheal tubes and catheters 失效
标题翻译：用于气管内导管和导管的自动染料分散剂
公开(公告)号：US5103817A
公开(公告)日：1992-04-14
申请号：US556605
申请日：1990-07-20
申请人： Dennis J. Reisdorf , James B. Hissong
发明人： Dennis J. Reisdorf , James B. Hissong
IPC分类号： A61M16/04
CPC分类号： A61M16/04 , A61M16/0436
摘要： An indwelling device for passing fluids into or out of the body includes an inflatable cuff for lodging the device within a body passage. The inflatable cuff is inflated with a fluid such as saline. Prior to the inflation process a dye dispersant material such as methylene blue is incorporated in dry form within the inflation cuff and/or within an inflation lumen which leads to the inflation cuff and/or within a pilot balloon which is accessed by a source of saline fluid. Thus, as the cuff is inflated with saline, the methylene blue dissolves and disperses in the saline enabling the saline to take on the color of the methylene blue dye. A buffer is combined with the methylene blue to enhance the dispersal of the dye in the saline. Potential piercing of the expanded cuff after it is filled with methylene blue provides a blue stain or leak that is easily recognized as a sign of damage to the cuff. Correction steps can thus be taken to repair or replace the endotracheal tube as soon as the leak is recognized.
摘要翻译：用于将流体流入或流出身体的留置装置包括用于将身体通道内的装置倒放的可充气套囊。充气袖口用诸如盐水的流体充气。在充气过程之前，染料分散剂材料例如亚甲基蓝以干燥的形式并入充气袖口内和/或在膨胀腔内，或者在导致充气袖带和/或在由气源流体。因此，当袖带用盐水充气时，亚甲蓝溶解并分散在盐水中，使得盐水能够承受亚甲蓝染料的颜色。将缓冲液与亚甲基蓝结合以增强染料在盐水中的分散。膨胀的袖口充满亚甲基蓝色后，潜在的穿孔可以提供蓝色污迹或泄漏，容易被认为是对袖口造成伤害的征兆。因此，一旦发现泄漏，就可以采取校正步骤来修复或更换气管内管。

2. 发明授权

US06361526B1 Antimicrobial tympanostomy tube 有权
公开(公告)号：US06361526B1
公开(公告)日：2002-03-26
申请号：US09291151
申请日：1999-04-12
申请人： Dennis J. Reisdorf , James B. Hissong
发明人： Dennis J. Reisdorf , James B. Hissong
IPC分类号： A61M532
CPC分类号： A61F11/002
摘要： An antimicrobial tympanostomy tube used to alleviate bacteriostatic infections following myringotomy which is compatible with otologic tissue associated with the middle ear. The tube is formed from a microporous thermoplastic or thermoset resin having incorporated therein 0.5 to about 15% by weight of a silver compound capable of migrating to the surface of tube sidewalls to impart a therapeutically effective level of antibacterial activity throughout the sidewall surface so as to provide long-term prevention of infections which may otherwise result during or after surgery or implantation of the tube.

3. 发明授权

US06689302B2 Method of making an antimicrobial tympanostomy tube 失效
标题翻译：制作抗菌鼓膜造口管的方法
公开(公告)号：US06689302B2
公开(公告)日：2004-02-10
申请号：US10106930
申请日：2002-03-26
申请人： Dennis J. Reisdorf , James B. Hissong
发明人： Dennis J. Reisdorf , James B. Hissong
IPC分类号： B29C4516
CPC分类号： A61F11/002
摘要： An antimicrobial tympanostomy tube used to alleviate bacteriostatic infections following myringotomy which is compatible with otologic tissue associated with the middle ear. The tube is formed from a microporous thermoplastic or thermoset resin having incorporated therein 0.5 to about 15% by weight of a silver compound capable of migrating to the surface of tube sidewalls to impart a therapeutically effective level of antibacterial activity throughout the sidewall surface so as to provide long-term prevention of infections which may otherwise result during or after surgery or implantation of the tube.
摘要翻译：一种抗微生物鼓膜造口管，用于缓解与中耳相关的耳蜗组织相容的鼓膜切开术后的抑菌感染。管由微孔热塑性树脂或热固性树脂形成，其中加入了0.5至约15重量％的能够迁移到管侧壁表面的银化合物，以赋予整个侧壁表面治疗有效水平的抗菌活性，从而提供长期预防在手术期间或手术或植入后可能导致的感染。

4. 发明授权

US5669501A Package and method for delivering a medical implant 失效
标题翻译：用于输送医疗植入物的包装和方法
公开(公告)号：US5669501A
公开(公告)日：1997-09-23
申请号：US658283
申请日：1996-06-05
申请人： James B. Hissong , John E. Studer
发明人： James B. Hissong , John E. Studer
IPC分类号： A61B19/02 , A61F2/00 , A61B19/00
CPC分类号： A61F2/0095 , A61B50/20 , A61B50/30 , A61B50/33 , A61B2050/0059 , A61B2050/3008 , A61B2050/3009 , A61F2002/183
摘要： A package for sterile delivery of medical implants such as, for example, wire piston prostheses, includes a tray defining a compartment, an insert removably disposed in the tray, and a lid mounted by the tray for sliding movement relative thereto. The medical implant is held by the insert in a specific position above a bottom wall of the compartment and with a longitudinal axis of the implant aligned with a recess in a wall of the compartment to permit the implant to be grasped with forceps for proper presentation at the operative site.
摘要翻译：用于医疗植入物例如线活塞假体的无菌递送的包装包括限定隔室的托盘，可移除地设置在托盘中的插入件和由托盘安装的用于相对于其滑动运动的盖子。医疗植入物由插入物保持在隔室的底壁上方的特定位置，并且植入物的纵向轴线与隔室的壁中的凹部对准，以允许用钳子抓住植入物以适当地呈现在手术部位。

5. 发明授权

US5531752A Vocal cord medialization tool 失效
标题翻译：声带中介工具
公开(公告)号：US5531752A
公开(公告)日：1996-07-02
申请号：US10914
申请日：1993-01-29
申请人： James L. Netterville , James B. Hissong
发明人： James L. Netterville , James B. Hissong
IPC分类号： A61B17/24 , A61F2/20 , A61B17/58
CPC分类号： A61B17/24 , A61F2/20 , Y10S128/21
摘要： A vocal cord medialization prosthesis includes a preformed and presized vocal cord engagement member. The engagement member has a base surface and an engagement surface that is inclined a predetermined amount with respect to the base surface. Measurement indicia is provided on the engagement member to indicate elevation of the engagement surface at predetermined points along the prosthesis. A vocal cord medialization tool is used to measure displacement of a vocal cord to an optimum phonation and breathing position before insertion of the prosthesis. The medialization tool provides measurements that correspond to sizing indicia on the prosthesis. The prosthesis can thus be trimmed to eliminate elevations that are unnecessary for obtaining optimum positioning of a vocal cord. One embodiment of the medialization tool also includes provision for measuring the thickness of a thyroid cartilage.
摘要翻译：声带内侧假体包括预成形和预先设定的声带接合构件。接合构件具有基面和相对于基面倾斜预定量的接合表面。在接合构件上设置有测量标记，以指示沿着假体的预定点处的接合表面的高度。在插入假体之前，使用声带中介工具来测量声带的位移到最佳的发音和呼吸位置。中间化工具提供对应于假体上的尺寸标记的测量。因此可以修剪假体以消除为获得声带的最佳定位而不必要的高度。中间化工具的一个实施例还包括用于测量甲状软骨的厚度的设置。

6. 发明授权

US5201765A Vocal cord medialization prosthesis 失效
标题翻译： VOCAL CORD MEDIALIZATION PROSTHESIS
公开(公告)号：US5201765A
公开(公告)日：1993-04-13
申请号：US763390
申请日：1991-09-20
申请人： James L. Netterville , James B. Hissong
发明人： James L. Netterville , James B. Hissong
IPC分类号： A61B17/24 , A61F2/20
CPC分类号： A61B17/24 , A61F2/20 , Y10S128/21
摘要： A vocal cord medialization prosthesis includes a preformed and presized vocal cord engagement member. The engagement member has a base surface and an engagement surface that is inclined a predetermined amount with respect to the base surface. Measurement indicia is provided on the engagement member to indicate elevation of the engagement surface at predetermined points along the prosthesis. A vocal cord medialization tool is used to measure displacement of a vocal cord to an optimum phonation and breathing position before insertion of the prosthesis. The medialization tool provides measurements that correspond to sizing indicia on the prosthesis. The prosthesis can thus be trimmed to eliminate elevations that are unnecessary for obtaining optimum positioning of a vocal cord. One embodiment of the medialization tool also includes provision for measuring the thickness of a thyroid cartilage.

7. 发明授权

US09227088B2 Methods of using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions 有权
标题翻译：使用高强度聚焦超声波形成包含多个病变的消融组织区域的方法
公开(公告)号：US09227088B2
公开(公告)日：2016-01-05
申请号：US12772437
申请日：2010-05-03
申请人： James B. Hissong , Mark T. Stewart , David E. Francischelli , James R. Keough , James R. Skarda , Hotaik Lee , Nadine B. Smith
发明人： James B. Hissong , Mark T. Stewart , David E. Francischelli , James R. Keough , James R. Skarda , Hotaik Lee , Nadine B. Smith
IPC分类号： A61B5/05 , A61N7/02 , A61B19/00 , A61B18/00 , A61N7/00 , A61B8/00
CPC分类号： A61B17/320068 , A61B8/4281 , A61B34/20 , A61B2017/320076 , A61B2017/320078 , A61B2018/00291 , A61B2034/2051 , A61B2090/378 , A61B2090/3782 , A61N7/02 , A61N7/022 , A61N2007/0078
摘要： A device and method for ablating tissue is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding an ablating member within the patient while tracking the position of the ablating member in the patient, positioning the ablating member in a desired position to ablate tissue, emitting ablating energy from the ablating member to form an ablated tissue area and removing the ablating member from the patient.
摘要翻译：公开了一种用于消融组织的装置和方法，包括以下步骤：获取患者的解剖图像，将图像与患者相关联，在跟踪患者内的消融部件的位置的同时引导患者内的消融部件，定位消融成员在消融组织的期望位置，从烧蚀构件发出消融能量以形成消融的组织区域，并从患者身上移除消融部件。

8. 发明授权

US08221402B2 Method for guiding a medical device 有权
标题翻译：医疗器械引导方法
公开(公告)号：US08221402B2
公开(公告)日：2012-07-17
申请号：US11298282
申请日：2005-12-09
申请人： David E. Francischelli , James B. Hissong , James R. Keogh , James R. Skarda , Mark T. Stewart
发明人： David E. Francischelli , James B. Hissong , James R. Keogh , James R. Skarda , Mark T. Stewart
IPC分类号： A61B18/04 , A61B18/08
CPC分类号： A61N7/02 , A61B8/4272 , A61B18/1442 , A61B34/20 , A61B2017/00243 , A61B2018/00291 , A61B2034/2051 , A61B2034/2053 , A61B2034/2063 , A61B2090/378 , A61B2090/397 , A61N7/022 , A61N2007/0078
摘要： A device and method for ablating tissue is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding an ablating member within the patient while tracking the position of the ablating member in the patient, positioning the ablating member in a desired position to ablate tissue, emitting ablating energy from the ablating member to form an ablated tissue area and removing the ablating member from the patient.
摘要翻译：公开了一种用于消融组织的装置和方法，包括以下步骤：获取患者的解剖图像，将图像与患者相关联，在跟踪患者内的消融部件的位置的同时引导患者内的消融部件，定位消融成员在消融组织的期望位置，从烧蚀构件发出消融能量以形成消融的组织区域，并从患者身上移除消融部件。

9. 发明授权

US06958043B2 Apparatus and method for displacing the partition between the middle ear and the inner ear using a manually powered device 有权
标题翻译：使用手动动力的装置来移动中耳和内耳之间的分隔物的装置和方法
公开(公告)号：US06958043B2
公开(公告)日：2005-10-25
申请号：US10151302
申请日：2002-05-21
申请人： James B. Hissong
发明人： James B. Hissong
IPC分类号： A61F11/00 , A61B5/00 , A61M31/00
CPC分类号： A61F11/00
摘要： Apparatus and method for treating a disease or condition of the ear, such as Meniere's disease or endolymphatic hydrops, includes a manual device operable by hand to pressurize air and pressure transmitting arrangement for delivering the pressurized air to the middle ear, preferably in pulses, to displace the partition between the middle ear and the inner ear to influence fluid in the inner ear.
摘要翻译：用于治疗诸如梅尼埃氏病或内淋巴积水之类的耳朵疾病或病症的装置和方法包括手动装置，其可手动加压空气和压力传递装置，用于将压缩空气输送至中耳，优选以脉冲传递至置换中耳和内耳之间的分隔物以影响内耳中的流体。

10. 发明授权

US06413254B1 Method of tongue reduction by thermal ablation using high intensity focused ultrasound 有权
标题翻译：使用高强度聚焦超声波进行热消融治疗舌苔的方法
公开(公告)号：US06413254B1
公开(公告)日：2002-07-02
申请号：US09487707
申请日：2000-01-19
申请人： James B. Hissong , Fred B. Dinger
发明人： James B. Hissong , Fred B. Dinger
IPC分类号： A61N118
CPC分类号： A61N7/022 , A61B17/24 , A61N2007/0078 , A61N2007/027
摘要： A method of tongue reduction by thermal ablation using high intensity focused ultrasound includes the steps of introducing an ultrasound emitting member in a patient's oral cavity, positioning the ultrasound emitting member adjacent an external surface of the tongue, emitting ultrasound energy from the ultrasound emitting member into tissue of the tongue, focusing the ultrasound energy within the tongue at a focusing zone contained in a target area disposed beneath the external surface, heating the tissue with the focused ultrasound energy such that the tissue at the target area is heated to an ablative temperature to form a lesion and withdrawing the ultrasound emitting member from the oral cavity. The lesion is allowed to be absorbed by the patient's body and/or to remain as altered tissue such that the tongue is reduced in size to correspondingly increase the size of the patient's airway and/or is stiffened to resist vibration. The lesion begins a predetermined distance from the external surface of the tongue such that the mucosa remains undamaged and preserved.
摘要翻译：通过使用高强度聚焦超声波的热消融来减少舌头的方法包括以下步骤：在患者的口腔内引入超声发射部件，将超声发射部件邻近舌的外表面定位，从超声发射部件发射超声波能量舌头的组织将超声能量聚焦在舌头内的聚焦区域，该聚焦区域包含在设置在外表面下方的目标区域中，用聚焦超声能量加热组织，使得目标区域上的组织被加热到烧蚀温度形成病变并从口腔抽出超声发射构件。允许病变被患者的身体吸收和/或保留为改变的组织，使得舌头的尺寸减小以相应地增加患者的气道的尺寸和/或被加强以抵抗振动。病变从舌头的外表面开始预定的距离，使得粘膜保持未受损和保存。

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