专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08178709B2 Iron preparation suitable for pharmaceutical formulation and process for the preparation thereof 失效
标题翻译：适用于药物制剂的铁制剂及其制备方法
公开(公告)号：US08178709B2
公开(公告)日：2012-05-15
申请号：US12506408
申请日：2009-07-21
申请人： Deanna Jean Nelson , Brian J. Mosley
发明人： Deanna Jean Nelson , Brian J. Mosley
IPC分类号： C07F9/09 , A61K31/295
CPC分类号： A61K31/194 , A61K33/26 , A61K33/42 , A61K45/06 , A61K2300/00 , A61K33/00
摘要： New iron preparations comprising stable, unpolymerized iron(III) citrate complex compositions and methods for their preparation are provided. Further, the invention involves the use stable, unpolymerized iron(III) citrate complex compositions of the invention as a food additive, nutritional supplement, dietary supplement, medical food, nutrient, iron fortificant, and source of iron in the fields of nutrition for humans, animals, fish, and birds and of diagnostics. The invention further involves the use of stable, unpolymerized iron(III) citrate complex compositions of the invention as a pharmaceutical and pharmacologically active ingredient for human clinical and veterinary applications.
摘要翻译：提供了包含稳定的未聚合的柠檬酸铁（III）络合物组合物的新铁制剂及其制备方法。此外，本发明涉及在人类营养领域中使用本发明的稳定的，未聚合的（III）柠檬酸铁配合物组合物作为食品添加剂，营养补充剂，膳食补充剂，医疗食品，营养物，铁的重要成分和铁源，动物，鱼和鸟以及诊断。本发明还涉及使用本发明的稳定的，未聚合的柠檬酸铁（III）络合物组合物作为用于人类临床和兽医应用的药物和药理学活性成分。

2. 发明申请

US20110021629A1 IRON PREPARATION SUITABLE FOR PHARMACEUTICAL FORMULATION AND PROCESS FOR THE PREPARATION THEREOF 失效
标题翻译：适用于药物制剂的铁制剂及其制备方法
公开(公告)号：US20110021629A1
公开(公告)日：2011-01-27
申请号：US12506408
申请日：2009-07-21
申请人： Deanna Jean Nelson , Brian J. Mosley
发明人： Deanna Jean Nelson , Brian J. Mosley
IPC分类号： A61K31/295
CPC分类号： A61K31/194 , A61K33/26 , A61K33/42 , A61K45/06 , A61K2300/00 , A61K33/00
摘要： New iron preparations comprising stable, unpolymerized iron(III) citrate complex compositions and methods for their preparation are provided. Further, the invention involves the use stable, unpolymerized iron(III) citrate complex compositions of the invention as a food additive, nutritional supplement, dietary supplement, medical food, nutrient, iron fortificant, and source of iron in the fields of nutrition for humans, animals, fish, and birds and of diagnostics. The invention further involves the use of stable, unpolymerized iron(III) citrate complex compositions of the invention as a pharmaceutical and pharmacologically active ingredient for human clinical and veterinary applications.
摘要翻译：提供了包含稳定的未聚合的柠檬酸铁（III）络合物组合物的新铁制剂及其制备方法。此外，本发明涉及在人类营养领域中使用本发明的稳定的，未聚合的（III）柠檬酸铁配合物组合物作为食品添加剂，营养补充剂，膳食补充剂，医疗食品，营养物，铁的重要成分和铁源，动物，鱼和鸟以及诊断。本发明还涉及使用本发明的稳定的，未聚合的柠檬酸铁（III）络合物组合物作为用于人类临床和兽医应用的药物和药理学活性成分。

3. 发明申请

US20110098347A1 PHOSPHOROUS BINDER FOR TREATMENT OF KIDNEY DISEASE 审中-公开
标题翻译：用于治疗儿童疾病的磷酸盐粘合剂
公开(公告)号：US20110098347A1
公开(公告)日：2011-04-28
申请号：US12982085
申请日：2010-12-30
申请人： Deanna Jean Nelson
发明人： Deanna Jean Nelson
IPC分类号： A61K31/385 , A61P1/00
CPC分类号： A61K33/24 , A23L33/16 , A23V2002/00 , A61K31/19 , A61K31/385 , A61K33/06 , A61K2300/00 , A23V2200/32 , A23V2250/1578
摘要： The present invention relates to oral compositions which are useful for binding phosphorus in ingesta, and inhibiting absorption of phosphorus from the gastrointestinal tract of subjects. A method for binding phosphorus in ingesta and inhibiting its absorption from the gastrointestinal tract is also provided. The dietary supplements and pharmaceutical products and methods of the present invention are particularly useful in the treatment of hyperphosphatemia of chronic uremia and reducing serum phosphorus levels in patients requiring such therapy.
摘要翻译：本发明涉及可用于结合摄入磷中的磷并抑制磷从受试者胃肠道吸收的口服组合物。还提供了一种在摄入中结合磷并抑制其从胃肠道吸收的方法。本发明的膳食补充剂和药物产品和方法特别可用于治疗需要这种治疗的患者中慢性尿毒症的高磷酸血症并降低血清磷水平。

4. 发明授权

US07157444B2 Aminosalicylate derivatives for treatment of inflammatory bowel disease 失效
标题翻译：氨基水杨酸衍生物用于治疗炎性肠病
公开(公告)号：US07157444B2
公开(公告)日：2007-01-02
申请号：US10688585
申请日：2003-10-18
申请人： Deanna Jean Nelson
发明人： Deanna Jean Nelson
IPC分类号： A61K31/715 , C07H5/04 , C07H5/06 , C07H1/00 , C08B37/08
CPC分类号： C07H5/04
摘要： Therapeutic 5-aminosalicylic acid derivative compositions having general formula (I), wherein R is a 1-deoxy sugar residue or a poly(ethylene glycol) chain-containing residue, are provided. The compositions enable topical delivery of 5-aminosalicylic acid to the gastrointestinal tract following oral administration in pharmaceutical preparations. According to the invention, the compositions stabilize pharmaceutical compositions containing therapeutic 5-aminosalicylic acid derivatives in a manner that enhances the retention of said compositions in the intestine, decreases the cellular absorption thereof, and decreases the transfer of said compositions or the 5-aminosalicylic acid derived therefrom to the systemic circulation
摘要翻译：提供具有通式（I）的治疗性5-氨基水杨酸衍生物组合物，其中R为1-脱氧糖残基或含聚乙二醇链的残基。该组合物能够在药物制剂中口服给药后将5-氨基水杨酸局部递送至胃肠道。根据本发明，组合物稳定含有治疗性5-氨基水杨酸衍生物的药物组合物，其方法是增强所述组合物在肠中的保留性，降低其细胞吸收，并降低所述组合物或5-氨基水杨酸的转移从其衍生到体循环

5. 发明申请

US20090239914A1 Phosphorus binder for treatment of renal disease 有权
标题翻译：用于治疗肾脏疾病的磷结合剂
公开(公告)号：US20090239914A1
公开(公告)日：2009-09-24
申请号：US12077777
申请日：2008-03-20
申请人： Deanna Jean Nelson
发明人： Deanna Jean Nelson
IPC分类号： A61K31/41
CPC分类号： A61K31/205 , A23L33/165 , A23L33/175 , A61K31/41 , A61K2300/00
摘要： The present invention relates to oral compositions which are useful for binding phosphorus in ingesta, and inhibiting absorption of phosphorus from the gastrointestinal tract of subjects. A method for binding phosphorus in ingesta and inhibiting its absorption from the gastrointestinal tract is also provided. The dietary supplements and pharmaceutical products and methods of the present invention are particularly useful in the treatment of hyperphosphatemia of chronic uremia and reducing serum phosphorus levels in patients requiring such therapy.
摘要翻译：本发明涉及口服组合物，其可用于结合摄入中的磷，并抑制磷从受试者的胃肠道吸收。还提供了一种在摄入中结合磷并抑制其从胃肠道吸收的方法。本发明的膳食补充剂和药物产品和方法特别可用于治疗需要这种治疗的患者中慢性尿毒症的高磷酸血症并降低血清磷水平。

6. 发明授权

US07456216B2 Methods for the preparation and formulation of l-carnitine valproate salts 有权
标题翻译：制备和制备丙戊酸盐酸1-肉碱的方法
公开(公告)号：US07456216B2
公开(公告)日：2008-11-25
申请号：US11725378
申请日：2007-03-19
申请人： Deanna Jean Nelson , Navdeep Balkrishna Malkar
发明人： Deanna Jean Nelson , Navdeep Balkrishna Malkar
IPC分类号： A61K31/195 , C07C229/00
CPC分类号： A61K31/197 , C07C229/22
摘要： The present invention relates to methods for preparing an L-carnitine valproate salt and administering this compound to a subject in need of treatment with valproate. Pharmaceutical compositions are also provided that are useful therapies for the treatment of neurological, immunological, and viral-mediated disorders in warm-blooded mammals.
摘要翻译：本发明涉及制备左旋肉碱丙戊酸盐的方法，并将该化合物给予需要用丙戊酸酯治疗的受试者。还提供了药物组合物，其是用于治疗温血哺乳动物中神经学，免疫学和病毒介导的疾病的有用治疗方法。

7. 发明申请

US20080234514A1 Methods for the preparation, formulation and use of lithium valproate 失效
公开(公告)号：US20080234514A1
公开(公告)日：2008-09-25
申请号：US12082878
申请日：2008-04-15
申请人： Navdeep B. Malkar , Deanna Jean Nelson , Walter C. Holberg
发明人： Navdeep B. Malkar , Deanna Jean Nelson , Walter C. Holberg
IPC分类号： C07C53/00
CPC分类号： A61K31/19 , C07C51/412 , C07C53/128
摘要： The present invention relates to methods for preparing lithium valproate and administering this compound to a subject in need of treatment with lithium and/or valproate. Pharmaceutical compositions are also provided that are useful therapies for the treatment of neurological, immunological, and viral-mediated disorders in warm-blooded mammals.

8. 发明授权

US07862836B2 Phosphorus binder for treatment of kidney disease 有权
标题翻译：用于治疗肾脏疾病的磷结合剂
公开(公告)号：US07862836B2
公开(公告)日：2011-01-04
申请号：US11402545
申请日：2006-04-12
申请人： Deanna Jean Nelson
发明人： Deanna Jean Nelson
IPC分类号： A61K33/34 , A61K33/06 , A61K31/385 , A61K31/19
CPC分类号： A61K33/24 , A23L33/16 , A23V2002/00 , A61K31/19 , A61K31/385 , A61K33/06 , A61K2300/00 , A23V2200/32 , A23V2250/1578
摘要： The present invention relates to oral compositions which are useful for binding phosphorus in ingesta, and inhibiting absorption of phosphorus from the gastrointestinal tract of subjects. A method for binding phosphorus in ingesta and inhibiting its absorption from the gastrointestinal tract is also provided. The dietary supplements and pharmaceutical products and methods of the present invention are particularly useful in the treatment of hyperphosphatemia of chronic uremia and reducing serum phosphorus levels in patients requiring such therapy.
摘要翻译：本发明涉及口服组合物，其可用于结合摄入中的磷，并抑制磷从受试者的胃肠道吸收。还提供了一种在摄入中结合磷并抑制其从胃肠道吸收的方法。本发明的膳食补充剂和药物产品和方法特别可用于治疗需要这种治疗的患者中慢性尿毒症的高磷酸血症并降低血清磷水平。

9. 发明授权

US07449598B2 Methods for the preparation, formulation and use of lithium valproate 失效
标题翻译：制备，制备和使用丙戊酸锂的方法
公开(公告)号：US07449598B2
公开(公告)日：2008-11-11
申请号：US11725414
申请日：2007-03-19
申请人： Navdeep B. Malkar , Deanna Jean Nelson , Walter C. Holberg, III
发明人： Navdeep B. Malkar , Deanna Jean Nelson , Walter C. Holberg, III
IPC分类号： C07C53/00
CPC分类号： A61K31/19 , C07C51/412 , C07C53/128
摘要： The present invention relates to methods for preparing lithium valproate and administering this compound to a subject in need of treatment with lithium and/or valproate. Pharmaceutical compositions are also provided that are useful therapies for the treatment of neurological, immunological, and viral-mediated disorders in warm-blooded mammals.
摘要翻译：本发明涉及制备丙戊酸锂并将该化合物施用于需要用锂和/或丙戊酸酯处理的受试者的方法。还提供了药物组合物，其是用于治疗温血哺乳动物中神经学，免疫学和病毒介导的疾病的有用治疗方法。

10. 发明授权

US06821529B2 Oligo(ethylene glycoll)-terminated 1,2-dithiolanes and their conjugates useful for preparing self-assembled monolayers 失效
标题翻译：低聚（乙二醇） - 终止的1,2-二硫戊环和它们的共轭物可用于制备自组装单层
公开(公告)号：US06821529B2
公开(公告)日：2004-11-23
申请号：US09946023
申请日：2001-09-05
申请人： Deanna Jean Nelson
发明人： Deanna Jean Nelson
IPC分类号： A61K3800
CPC分类号： B82Y30/00 , A61K31/50 , A61K38/28 , A61K47/60 , C07D339/04 , Y10S530/811 , Y10S530/815
摘要： The present invention provides biotechnologically useful oligo(ethylene glycol)-terminated 1,2-dithiolane compositions and conjugates of these compositions with biological or non-biological receptor, ligand, sequestering, or reporter moieties. The invention also provides methods for the preparation of these compositions. Further, the invention provides self-assembled monolayer (SAM) compositions on a metal and methods for their preparation.
摘要翻译：本发明提供生物技术上有用的寡聚（乙二醇） - 终止的1,2-二硫戊环组合物和这些组合物与生物或非生物受体，配体，多价螯合或报告物部分的缀合物。本发明还提供了制备这些组合物的方法。此外，本发明提供了金属上的自组装单层（SAM）组合物及其制备方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式