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1. 发明申请

US20090245612A1 AUTOMATED IMAGE ANALYSIS 审中-公开
标题翻译：自动图像分析
公开(公告)号：US20090245612A1
公开(公告)日：2009-10-01
申请号：US12480452
申请日：2009-06-08
申请人： David Zahniser , Kam Lin Wong , Jim Linder , Douglas Tenney
发明人： David Zahniser , Kam Lin Wong , Jim Linder , Douglas Tenney
IPC分类号： G06K9/00
CPC分类号： G01N15/1475 , G01N2015/1006 , G06K9/00127 , G06T7/0012 , G06T2207/20212 , G06T2207/30024 , Y10S128/922
摘要： One automated imaging process, as described herein, includes: a) obtaining digital images of objects in a biological sample; b) selecting a plurality of objects of interest from the digital images; c) obtaining multiple images of the selected objects of interest at a plurality of different wavelengths; d) combining one of said multiple images with a corresponding digital image to produce a combined image; and e) analyzing the combined image in order to characterize the biological sample.
摘要翻译：如本文所述的一个自动成像过程包括：a）获得生物样品中的物体的数字图像; b）从数字图像中选择多个感兴趣对象; c）以多个不同的波长获得所选择的目标对象的多个图像; d）将所述多个图像中的一个与相应的数字图像组合以产生组合图像; e）分析组合图像以表征生物样品。

2. 发明授权

US07587078B2 Automated image analysis 有权
标题翻译：自动图像分析
公开(公告)号：US07587078B2
公开(公告)日：2009-09-08
申请号：US11120437
申请日：2005-05-02
申请人： David Zahniser , Kam Lin Wong , Jim Linder , Douglas Tenney
发明人： David Zahniser , Kam Lin Wong , Jim Linder , Douglas Tenney
IPC分类号： G06K9/00
CPC分类号： G01N15/1475 , G01N2015/1006 , G06K9/00127 , G06T7/0012 , G06T2207/20212 , G06T2207/30024 , Y10S128/922
摘要： One automated imaging process, as described herein, includes: a) obtaining digital images of objects in a biological sample; b) selecting a plurality of objects of interest from the digital images; c) obtaining multiple images of the selected objects of interest at a plurality of different wavelengths; d) combining one of said multiple images with a corresponding digital image to produce a combined image; and e) analyzing the combined image in order to characterize the biological sample.
摘要翻译：如本文所述的一个自动成像过程包括：a）获得生物样品中的物体的数字图像; b）从数字图像中选择多个感兴趣对象; c）以多个不同的波长获得所选择的目标对象的多个图像; d）将所述多个图像中的一个与相应的数字图像组合以产生组合图像; e）分析组合图像以表征生物样品。

3. 发明申请

US20060245630A1 Automated image analysis 有权
公开(公告)号：US20060245630A1
公开(公告)日：2006-11-02
申请号：US11120437
申请日：2005-05-02
申请人： David Zahniser , Kam Wong , Jim Linder , Douglas Tenney
发明人： David Zahniser , Kam Wong , Jim Linder , Douglas Tenney
IPC分类号： G06K9/00
CPC分类号： G01N15/1475 , G01N2015/1006 , G06K9/00127 , G06T7/0012 , G06T2207/20212 , G06T2207/30024 , Y10S128/922
摘要： One automated imaging process, as described herein, includes: a) obtaining digital images of objects in a biological sample; b) selecting a plurality of objects of interest from the digital images; c) obtaining multiple images of the selected objects of interest at a plurality of different wavelengths; d) combining one of said multiple images with a corresponding digital image to produce a combined image; and e) analyzing the combined image in order to characterize the biological sample.

4. 发明申请

US20070099291A1 Ambient pressure monitor and method of preparing biological specimens 审中-公开
标题翻译：环境压力监测仪及生物标本制备方法
公开(公告)号：US20070099291A1
公开(公告)日：2007-05-03
申请号：US11267529
申请日：2005-11-03
申请人： Douglas Tenney
发明人： Douglas Tenney
IPC分类号： C12M1/34
CPC分类号： G01N1/4077
摘要： A filtration based biological specimen collection and transfer device includes a vacuum source, a vacuum conduit configured to connect the vacuum source to a filter cartridge, an internal pressure monitor configured to measure an apparent pressure inside of the filter cartridge, an internal pressure monitor conduit configured to connect the internal pressure monitor to the filter cartridge, an ambient pressure monitor configured to measure an ambient pressure, and a controller operatively connected to the vacuum source, the internal pressure monitor, and the ambient pressure monitor. The controller is configured to calculate a true pressure inside of the filter cartridge based on a measured apparent pressure and a measured change in the ambient pressure. A method of collecting a biological specimen comprising measuring an apparent pressure inside of a filter cartridge, measuring an ambient pressure, calculating a true pressure inside of the filter cartridge using the respective measured apparent pressure and ambient pressure, deactivating the vacuum source when the true pressure inside of the filter cartridge falls below a predetermined pressure, allowing the true pressure inside of the filter to return to approximately the ambient pressure, and calculating a membrane occlusion percentage.
摘要翻译：基于过滤的生物样本收集和转移装置包括真空源，被配置为将真空源连接到过滤器滤芯的真空导管，配置成测量滤筒内的视在压力的内部压力监测器，将内部压力监视器连接到过滤器滤芯，配置为测量环境压力的环境压力监视器，以及可操作地连接到真空源，内部压力监视器和环境压力监视器的控制器。控制器被配置为基于测量的表观压力和测量的环境压力的变化来计算滤筒内部的真实压力。一种收集生物样本的方法，包括测量滤筒内的表观压力，测量环境压力，使用各自测量的表观压力和环境压力计算滤筒内部的真实压力，当真空压力过滤器滤芯的内部下降到预定压力以下，允许过滤器内部的真实压力返回到大致的环境压力，并计算膜阻塞百分数。

5. 发明申请

US20070125170A1 Fluid level regulator 失效
标题翻译：液位调节器
公开(公告)号：US20070125170A1
公开(公告)日：2007-06-07
申请号：US11292840
申请日：2005-12-01
申请人： Douglas Tenney
发明人： Douglas Tenney
IPC分类号： G01F23/00
CPC分类号： G01F23/296 , C12M33/04 , G01F23/14 , G01F23/292 , G01N2035/1025 , G05D9/12 , Y10T137/0396 , Y10T137/7287
摘要： A biological specimen collection and transfer system, comprises a biological sample container configured for storing a biological fluid sample, and a fluid level regulator configured to determine a fluid level in the biological sample container and to dispense a fluid into the container if the determined fluid level is less than a desired fluid level. A method of regulating a fluid level of a biological fluid sample in a container during a process of transferring biological matter in the fluid sample to a specimen slide, the method comprises monitoring a pressure of an interior chamber of a specimen filter, the chamber coupled to a vacuum source and having one end submerged in the fluid sample, determining a fluid level of the fluid sample in the container based on a detected change in pressure of the specimen filter chamber, and adding a liquid to the container if the determined fluid level is less than a desired fluid level.
摘要翻译：一种生物样本收集和传送系统，包括构造成存储生物流体样品的生物样本容器，以及液体水平调节器，其被配置为确定生物样品容器中的液体水平，并且如果确定的液面水平小于期望的液位。一种在将流体样品中的生物物质转移到试样载玻片的过程中调节容器中生物流体样品的液面的方法，该方法包括监测样品过滤器的内部室的压力，真空源，其一端浸没在流体样品中，基于检测到的样本过滤室的压力变化来确定容器中的流体样品的液位，并且如果确定的液位是小于期望的液位。

6. 发明申请

US20070125187A1 Filter contamination control device 有权
标题翻译：过滤污染控制装置
公开(公告)号：US20070125187A1
公开(公告)日：2007-06-07
申请号：US11292845
申请日：2005-12-01
申请人： Douglas Tenney
发明人： Douglas Tenney
IPC分类号： G01N1/22
CPC分类号： G01N1/24 , C12M33/02 , C12M33/14 , G01N2015/0088
摘要： A biological specimen filter, for use in a biological specimen collection and transfer system having a vacuum source, comprises a tubular body having an exterior surface, an interior chamber, a first end configured to couple to the vacuum source, and a second end having an opening in communication with the chamber, and a fluid trap extending around at least a portion of a circumference of the exterior surface of the tubular body and sized and shaped to catch fluid flowing along the exterior surface as the tubular body is inverted from a first position, in which the opening is submerged in a fluid source, to a second position, in which the opening is removed from the fluid source.
摘要翻译：用于具有真空源的生物样本收集和转移系统的生物样本过滤器包括具有外表面的管状体，内部室，被配置为耦合到真空源的第一端，以及具有开口与腔室连通，以及围绕管状体的外表面的圆周的至少一部分延伸的流体阱，其尺寸和形状被设计成当管状体从第一位置反转时沿着外表面流动流体，其中开口浸没在流体源中，到第二位置，其中开口从流体源移除。

7. 发明申请

US20050237607A1 Microscope slide mask and method 审中-公开
标题翻译：显微镜幻灯片和方法
公开(公告)号：US20050237607A1
公开(公告)日：2005-10-27
申请号：US10834689
申请日：2004-04-27
申请人： Douglas Tenney
发明人： Douglas Tenney
IPC分类号： G01N1/28 , G02B21/34 , B01L3/00 , B32B5/02 , B32B27/04 , B32B27/12 , G02B21/26
CPC分类号： G01N1/2813
摘要： A microscope slide assembly is provided. The microscope slide assembly comprises a slide and a mask with a window that defines an examination area on the slide. Preferably, the mask further comprises a tab to facilitate removal and markings to indicate its presence. Optionally, the mask further comprises a plurality of windows that define a plurality of respective examination areas on the slide. A method for transferring cells onto a microscope slide is also provided. The method comprises transferring cells to a slide with a mask disposed thereon, removing the mask to remove unwanted cells, and recovering the removed cells from the mask.
摘要翻译：提供显微镜滑块组件。显微镜滑块组件包括滑块和具有窗口的面罩，该窗口限定了滑块上的检查区域。优选地，掩模还包括突出部，以便于移除和标记以指示其存在。可选地，掩模还包括在滑块上限定多个相应检查区域的多个窗口。还提供了将细胞转移到显微镜载玻片上的方法。该方法包括将细胞转移到具有设置在其上的掩模的载玻片上，去除掩模以除去不想要的细胞，以及从掩模中回收去除的细胞。

8. 发明授权

US5718987A Lead-acid battery with inactive cell 失效
标题翻译：带惰性电池的铅酸电池
公开(公告)号：US5718987A
公开(公告)日：1998-02-17
申请号：US180085
申请日：1994-01-11
申请人： Sudhan Misra , Douglas Tenney , Franz Wagner
发明人： Sudhan Misra , Douglas Tenney , Franz Wagner
IPC分类号： H01M10/12 , H01M2/24 , H01M4/73
CPC分类号： H01M10/12
摘要： A lead-acid battery includes a compartmented case and a polarity of electrochemically lead-acid cells serially connected via respective positive and negative terminals. Each cell includes planar positive and negative plates and resides in one compartment of the case. The battery further includes an electrochemically inactive cell serially connected with the electrochemically active cells and being intermediately disposed respecting the electrochemically active cells. Plates of the inactive cell preferably have connecting lugs extending therefrom which align with corresponding connecting lugs of the positive and negative plates of the active cells. Rigid homogeneous foam separates the inactive cell plates from one another and fills the inactive cell compartment thereby providing support for the inactive cell plates.
摘要翻译：铅酸电池包括隔室和通过相应的正极和负极串联连接的电化学铅酸电池的极性。每个电池包括平面正极板和负极板，并且位于壳体的一个隔室中。电池还包括与电化学活性细胞串联连接的电化学惰性细胞，并且相对于电化学活性细胞被中间放置。非活性单元的板优选地具有从其延伸的连接凸耳，其与活性单元的正极板和负极板的相应连接凸耳对准。刚性均质泡沫将不活泼的细胞板彼此分离并填充惰性细胞室，从而为非活性细胞板提供支持。

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