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1. 发明授权

US4960884A Pesticidal 2-fluoroethyl ethers 失效
标题翻译：杀虫剂2-氟乙基醚
公开(公告)号：US4960884A
公开(公告)日：1990-10-02
申请号：US399448
申请日：1989-08-28
申请人： David M. Roush , Donald A. Shaw , Michael L. Jones , Jun H. Chang
发明人： David M. Roush , Donald A. Shaw , Michael L. Jones , Jun H. Chang
IPC分类号： A01N31/04 , A01N31/14 , A01N31/16 , A01N33/10 , A01N33/20 , A01N33/22 , A01N35/02 , A01N35/04 , A01N35/10 , A01N37/00 , A01N37/38 , A01N37/40 , A01N37/48 , A01N41/10 , A01N43/10 , A01N43/12 , C07C43/174 , C07C43/225 , C07C43/23 , C07C45/62 , C07C45/71 , C07C45/72 , C07C47/575 , C07C49/255 , C07C49/84 , C07C59/64 , C07C65/21 , C07C69/92 , C07C205/34 , C07C205/37 , C07C205/59 , C07C217/76 , C07C217/84 , C07C235/46 , C07C235/60 , C07C251/24 , C07C255/54 , C07C323/03
CPC分类号： C07C323/03 , A01N31/04 , A01N31/14 , A01N31/16 , A01N33/10 , A01N33/20 , A01N33/22 , A01N35/02 , A01N35/04 , A01N35/10 , A01N37/00 , A01N37/38 , A01N37/40 , A01N37/48 , A01N41/10 , A01N43/10 , A01N43/12 , C07C205/34 , C07C205/37 , C07C205/59 , C07C217/76 , C07C217/84 , C07C235/46 , C07C235/60 , C07C251/24 , C07C255/54 , C07C43/174 , C07C43/1742 , C07C43/1745 , C07C43/225 , C07C43/23 , C07C45/62 , C07C45/71 , C07C45/72 , C07C47/575 , C07C49/255 , C07C49/84 , C07C59/64 , C07C65/21 , C07C69/92
摘要： Pesticidal mono-, di-, and tri-2-fluoroethyl ethers of the formula R.sup.1 R.sup.2.sub.m Ar(OCH.sub.2 CH.sub.2 F).sub.n, compositions thereof and their insecticidal, acaricidal and nematicidal uses are described and claimed.
摘要翻译：描述和要求保护的式R1R2mAr（OCH2CH2F）n的杀虫单，二和三氟乙基醚及其杀虫，杀螨和杀线虫剂的组合物。

2. 发明授权

US08740873B2 Soft body catheter with low friction lumen 有权
标题翻译：软体导管低摩擦腔
公开(公告)号：US08740873B2
公开(公告)日：2014-06-03
申请号：US11724578
申请日：2007-03-15
申请人： Michael L. Jones , Frank R. Louw
发明人： Michael L. Jones , Frank R. Louw
IPC分类号： A61M25/00
CPC分类号： A61N5/1015 , A61L29/085 , A61M2025/0047
摘要： The disclosure is directed to radiation catheter devices, methods for controlled application of irradiation to tissue at a body site, such as a cavity formed after removal of tissue, e.g. cancer, using such radiation catheter devices, solutions for forming a more lubricious luminal surface and method for lining lumens of such devices to improve the frictional characteristics thereof. The catheter device includes a flexible elongated shaft which is formed of low durometer polymeric material, which can be readily folded or coiled for securing the shaft to or under the skin of the patient and a radiation lumen lined with high durometer polymeric material to improve the frictional characteristics. The elongated shaft has at least one inner lumen for receiving a radiation source which has a layer of high durometer polymeric material that provides lower surface friction to facilitate advancement of a radiation source therein.
摘要翻译：本公开涉及辐射导管装置，用于受控地应用照射到身体部位的组织的方法，例如在去除组织之后形成的空腔，例如，癌症，使用这种辐射导管装置，用于形成更加光滑的腔表面的解决方案以及用于衬里这些装置的流明以提高其摩擦特性的方法。导管装置包括柔性细长轴，其由低硬度聚合物材料形成，其可以容易地折叠或卷绕以将轴固定到患者的皮肤上或皮下，以及衬有高硬度聚合物材料的辐射腔，以改善摩擦特点细长轴具有用于接收辐射源的至少一个内腔，辐射源具有提供较低表面摩擦以便促进其中的辐射源的高硬度聚合材料层。

3. 发明授权

US08718745B2 Tissue site markers for in vivo imaging 有权
标题翻译：用于体内成像的组织位点标记
公开(公告)号：US08718745B2
公开(公告)日：2014-05-06
申请号：US12787177
申请日：2010-05-25
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick , Frank R. Louw , Stephen A. DeSantis
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick , Frank R. Louw , Stephen A. DeSantis
IPC分类号： A61B6/00
CPC分类号： A61B19/54 , A61B6/12 , A61B8/0833 , A61B90/39 , A61B2090/08021 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61B2090/3991 , A61M37/0069
摘要： An intracorporeal site marker has high ultrasound reflectivity, presents a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The biopsy site marker may include features to fix the marker to the biopsy site so as to resist migration from the biopsy cavity.
摘要翻译：体内位点标记物具有高超声反射率，从小标记物提供了显着的声学特征，以避免在随后的成像研究中模糊诊断组织特征，并且可以容易地与生物学特征区别开来。活检部位标记可以包括将标记物固定到活检部位以防止从活检腔迁移的特征。

4. 发明授权

US08361082B2 Marker delivery device with releasable plug 有权
标题翻译：带可释放插头的标记输送装置
公开(公告)号：US08361082B2
公开(公告)日：2013-01-29
申请号：US13037971
申请日：2011-03-01
申请人： Michael L. Jones , Paul Lubock , John Merritt
发明人： Michael L. Jones , Paul Lubock , John Merritt
IPC分类号： A61B17/00
CPC分类号： A61B5/064 , A61B5/055 , A61B5/062 , A61B6/12 , A61B8/0833 , A61B10/02 , A61B17/0057 , A61B90/39 , A61B2017/00637 , A61B2017/00898 , A61B2090/3908 , A61B2090/3925 , A61B2090/3954 , A61B2090/3966 , A61B2090/3987 , A61K49/12 , A61K49/18 , A61K2123/00 , A61M5/007 , A61M37/0069
摘要： A marker delivery device includes an elongated delivery cannula which has a distal end section, an inner lumen and a discharge opening in the distal end section in communication with the inner lumen. At least one elongated fibrous marker body is slidably disposed within the inner lumen of the elongated delivery cannula. The at least one elongated fibrous marker body includes a plurality of bioabsorbable polymeric strands. The strands are compressed to a compressed configuration and bound together in the compressed configuration with a polymer binding agent prior to insertion into the elongated delivery cannula. A releasable plug is disposed within a distal portion of the inner lumen and distal to the at least one elongated fibrous marker body so as to at least partially occlude the discharge opening in the distal end section.
摘要翻译：标记输送装置包括细长的输送套管，其具有与内腔连通的远端部分中的远端部分，内腔和排出口。至少一个细长的纤维标记物体可滑动地设置在细长的输送套管的内腔内。所述至少一个细长的纤维标记物主体包括多个生物可吸收的聚合物链。股线被压缩成压缩构型并且在插入细长的输送套管之前用压缩构型与聚合物粘合剂结合在一起。可释放插塞设置在内腔的远侧部分内并且远离至少一个细长纤维标记体，以至少部分地封闭远端部分中的排出口。

5. 发明申请

US20120277626A1 METHODS AND APPARATUS FOR SECURING MEDICAL INSTRUMENTS TO DESIRED LOCATIONS IN A PATIENT'S BODY 审中-公开
标题翻译：将医疗仪器安装在患者体内所需位置的方法和装置
公开(公告)号：US20120277626A1
公开(公告)日：2012-11-01
申请号：US13543309
申请日：2012-07-06
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
IPC分类号： A61B10/02
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2019/5487 , A61B2019/5491 , A61B2090/3908 , A61B2090/3991
摘要： A medical device for localization of tissue at a target site in a patient's body includes a tube having a distal end, a proximal end, and a longitudinal axis. The medical device is configured for placement of the distal end at the target site. A fixation device is disposed on the distal end. The affixation device is configured to mechanically fix the distal end of the medical device to tissue at the target site.
摘要翻译：用于在患者体内的靶部位定位组织的医疗装置包括具有远端，近端和纵向轴线的管。医疗装置被配置为将远端放置在目标位置处。固定装置设置在远端。固定装置构造成将医疗装置的远端机械地固定在目标部位的组织。

6. 发明授权

US08219182B2 Cavity-filling biopsy site markers 有权
标题翻译：腔填充活检部位标记
公开(公告)号：US08219182B2
公开(公告)日：2012-07-10
申请号：US12852286
申请日：2010-08-06
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones
IPC分类号： A61B8/00 , A61B6/00 , A61B8/14
CPC分类号： A61B8/481 , A61B6/12 , A61B8/0833 , A61B10/02 , A61B90/39 , A61B2017/00004 , A61B2090/3908 , A61B2090/392 , A61B2090/3925 , A61B2090/395 , A61B2090/3954 , A61B2090/3966 , A61B2090/3987 , A61B2090/3995 , A61K49/006 , A61K49/222 , A61M37/0069
摘要： An ultrasound-detectable biopsy marker mass has a detectable in-vivo lifetime during which the marker mass remains readily detectable by ultrasound imaging. The ultrasound-detectable biopsy marker mass is formed of particles of a bio-resorbable material having bubble cavities and having a particle size between about 200 microns and about 500 microns.
摘要翻译：超声检测的活检标记物质具有可检测的体内寿命，在此期间，通过超声成像可以容易地检测出标记物质。可超声检测的活检标记物质由具有气泡腔并具有约200微米至约500微米的粒度的生物可吸收材料的颗粒形成。

7. 发明授权

US08152737B2 Tissue specimen encapsulation device and method thereof 有权
标题翻译：组织标本包封装置及其方法
公开(公告)号：US08152737B2
公开(公告)日：2012-04-10
申请号：US11811952
申请日：2007-06-12
申请人： Fred H. Burbank , Richard L. Quick , Jacob Frank Louw , Michael L. Jones , Paul Lubock
发明人： Fred H. Burbank , Richard L. Quick , Jacob Frank Louw , Michael L. Jones , Paul Lubock
IPC分类号： A61B10/00 , A61B18/18 , A61B17/32
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00234 , A61B17/221 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1487 , A61B18/1492 , A61B90/37 , A61B2017/00287 , A61B2017/2212 , A61B2017/320064 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A device for encapsulating tissue specimens includes a wand assembly, a sheath, and a guide assembly. The guide assembly pulls, draws, or otherwise moves the sheath about the tissue specimen. The wand assembly is disposed proximate to the tissue specimen, typically either adjacent or through the specimen. In an aspect of the encapsulating device, the guide assembly has sheath deployment members that are disposed about the tissue specimen. The sheath, which is attached to ends of the sheath deployment members and the wand assembly, is drawn over the tissue specimen as the sheath deployment members are pushed or pulled. The guide assembly is an arm or a housing that rotates about the tissue specimen. The sheath, which is secured at one end to the guide assembly and at another end to the wand assembly, is drawn over the tissue specimen as the guide assembly rotates.
摘要翻译：用于封装组织样本的装置包括棒组件，护套和引导组件。引导组件拉动，牵引或以其他方式使护套围绕组织标本移动。棒组件靠近组织标本设置，通常是相邻的或通过样本。在封装装置的一个方面中，引导组件具有围绕组织标本设置的护套展开部件。当护套展开构件被推动或拉动时，附接到鞘展开构件和杆组件的端部的护套被拉过组织标本。引导组件是围绕组织标本旋转的臂或壳体。当引导组件旋转时，在一端固定到引导组件并且另一端固定到杆组件的护套在组织样本上被拉伸。

8. 发明申请

US20110237943A1 FIBROUS MARKER AND INTRACORPOREAL DELIVERY THEREOF 有权
标题翻译： FIBROUS MARKER和INTRACORPOREAL交付
公开(公告)号：US20110237943A1
公开(公告)日：2011-09-29
申请号：US13155628
申请日：2011-06-08
申请人： Michael L. Jones , Paul Lubock , Lloyd H. Malchow
发明人： Michael L. Jones , Paul Lubock , Lloyd H. Malchow
IPC分类号： A61B6/00
CPC分类号： A61B90/39 , A61B17/0057 , A61B2017/00637 , A61B2017/00898 , A61B2090/3908 , A61B2090/392 , A61B2090/3925 , A61B2090/3954 , A61B2090/3987
摘要： An intracorporeal marker includes a fibrous unitary marker body having bioabsorbable fibers compressed into a compressed configuration, and bound in the compressed configuration by a polymer binding agent. The intracorporeal marker may be incorporated into an intracorporeal marker delivery device having a delivery cannula which has a distal tip, an inner lumen and a discharge opening in communication with the inner lumen. The compression and binding occur prior to insertion of the fibrous unitary marker body into the inner lumen of the delivery cannula. The fibrous unitary marker body is slidably disposed within and pushable through the inner lumen of the elongated delivery cannula proximal to the discharge opening.
摘要翻译：体内标记包括具有压缩成压缩构型的生物可吸收纤维的纤维整体标记体，并且通过聚合物粘合剂以压缩构型结合。体内标记物可以并入具有输送套管的体内标记递送装置，所述输送套管具有与内腔连通的远侧末端，内腔和排出口。在将纤维整体标记物体插入输送套管的内腔之前发生压缩和束缚。纤维整体式标记物体可滑动地设置在靠近排出口的细长输送套管的内腔内并可推动穿过。

9. 发明申请

US20110201966A1 METHOD FOR MAINTAINING ACCESS TO A BIOPSY SITE 有权
标题翻译：维持对生物场地访问的方法
公开(公告)号：US20110201966A1
公开(公告)日：2011-08-18
申请号：US13095304
申请日：2011-04-27
申请人： Paul Lubock , Michael L. Jones
发明人： Paul Lubock , Michael L. Jones
IPC分类号： A61B10/02
CPC分类号： A61M29/02 , A61B10/0041 , A61B17/0218 , A61B90/02 , A61B2017/00557 , A61B2017/00796 , A61B2090/3908 , A61M25/10 , A61M29/00 , A61M2025/1095 , A61N5/1015
摘要： A method for maintaining access to a biopsy site within a patient, includes forming a passageway from an opening in an exterior site on the patient to a desired location for a biopsy specimen within the patient; removing a tissue specimen from the desired location thereby leaving a biopsy cavity; providing a temporary catheter having an elongate shaft, a flexible proximal shaft section, and a distal shaft section having a cavity filling member thereon; inserting the cavity filling member on the distal shaft section into the biopsy cavity; inflating the cavity filling member after inserting the cavity filling member within the biopsy cavity, but before closing the opening, using the flexible proximal shaft section; placing the flexible proximal shaft section at an intracorporeal location; and closing the opening so as to seal the passageway.
摘要翻译：一种用于维持进入患者体内的活检部位的方法，包括从病人的外部位置的开口形成通道，以在患者体内用于活检标本的期望位置; 从所需位置移除组织标本，从而留下活检腔; 提供具有细长轴，柔性近轴部分和在其上具有空腔填充构件的远端轴部分的临时导管; 将所述空腔填充构件插入所述远端轴部分到所述活检腔中; 将空腔填充构件插入到活检腔内，但是在使用柔性近端轴段关闭开口之前使空腔填充构件膨胀; 将柔性近轴部分放置在体内位置; 并关闭开口以密封通道。

10. 发明授权

US07983734B2 Fibrous marker and intracorporeal delivery thereof 有权
标题翻译：纤维标记和体内递送
公开(公告)号：US07983734B2
公开(公告)日：2011-07-19
申请号：US10444770
申请日：2003-05-23
申请人： Michael L. Jones , Paul Lubock , Lloyd H. Malchow
发明人： Michael L. Jones , Paul Lubock , Lloyd H. Malchow
IPC分类号： A61B6/00
CPC分类号： A61B90/39 , A61B17/0057 , A61B2017/00637 , A61B2017/00898 , A61B2090/3908 , A61B2090/392 , A61B2090/3925 , A61B2090/3954 , A61B2090/3987
摘要： The invention is directed to an intracorporeal marker, a delivery device and assembly for such marker and the method of delivering one or more of the markers to an intracorporeal location within a patient. The marker is a body formed at least in part of a bioabsorbable fibrous material such as a fibrous mat or fabric. The delivery devices preferably also include one or more bioabsorbable short term markers which are configured to expand within the body cavity due to contacting a body fluid. The fibrous marker has a radiographically detectable member which preferably hold a portion of the fibrous body in a compressed condition. Preferably, the fibrous marker has a fibrous felt core formed of bioabsorbable material with a fabric jacket formed of bioabsorbable material. Therapeutic, diagnostic and binding agents may be incorporated into the fibrous body of the marker.
摘要翻译：本发明涉及一种体内标记物，用于这种标记的递送装置和装置，以及将一种或多种标记递送到患者体内位置的方法。标记物是形成至少部分生物可吸收纤维材料如纤维垫或织物的主体。递送装置优选还包括一个或多个生物可吸收的短期标记物，其构造成由于接触体液而在体腔内膨胀。纤维标记具有可放射线检测的构件，其优选地将纤维体的一部分保持在压缩状态。优选地，纤维标记物具有由生物可吸收材料形成的纤维毡芯，其具有由生物可吸收材料形成的织物护套。可以将治疗性，诊断性和结合剂掺入标记物的纤维体内。

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