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1. 发明申请

US20090076497A1 Tissue surface treatment apparatus and method 有权
公开(公告)号：US20090076497A1
公开(公告)日：2009-03-19
申请号：US11893911
申请日：2007-08-17
申请人： David L. Morris , Steve A. Daniel , Daniel J. Balbierz
发明人： David L. Morris , Steve A. Daniel , Daniel J. Balbierz
IPC分类号： A61B18/14
CPC分类号： A61M25/1002 , A61B18/1477 , A61B2018/00011 , A61B2018/00017 , A61B2018/00029 , A61B2018/00291 , A61B2018/143 , A61B2018/1475 , A61M2025/0085
摘要： A method of controlling ablation volume depth includes providing a treatment apparatus. The apparatus comprises a housing having a proximal and distal end including a tissue contacting surface. The housing defines an interior with an energy delivery device positionable in the interior. The energy delivery device includes at least one electrode with a tissue penetrating distal end and is configured to be advanced from the interior into a target tissue site to define an ablation volume. An advancement device is coupled to the energy delivery device and is configured to advance the at least one electrode. The at least one electrode is advanced to a selected deployment depth beneath a tissue surface while avoiding a critical structure. Energy is delivered from the energy delivery device. An ablation volume is created at a controlled depth below the tissue surface responsive to the deployment depth while minimizing injury to the critical structure.

2. 发明授权

US07278991B2 Tissue surface treatment apparatus and method 有权
标题翻译：组织表面处理装置及方法
公开(公告)号：US07278991B2
公开(公告)日：2007-10-09
申请号：US09938276
申请日：2001-08-22
申请人： David L. Morris , Steve A. Daniel , Daniel J. Balbierz
发明人： David L. Morris , Steve A. Daniel , Daniel J. Balbierz
IPC分类号： A61B18/18
CPC分类号： A61M25/1002 , A61B18/1477 , A61B2018/00011 , A61B2018/00017 , A61B2018/00029 , A61B2018/00291 , A61B2018/143 , A61B2018/1475 , A61M2025/0085
摘要： A method of controlling ablation volume depth includes providing a treatment apparatus. The apparatus comprises a housing having a proximal and distal end including a tissue contacting surface. The housing defines an interior with an energy delivery device positionable in the interior. The energy delivery device includes at least one electrode with a tissue penetrating distal end and is configured to be advanced from the interior into a target tissue site to define an ablation volume. An advancement device is coupled to the energy delivery device and is configured to advance the at least one electrode. The at least one electrode is advanced to a selected deployment depth beneath a tissue surface while avoiding a critical structure. Energy is delivered from the energy delivery device. An ablation volume is created at a controlled depth below the tissue surface responsive to the deployment depth while minimizing injury to the critical structure.
摘要翻译：控制消融体积深度的方法包括提供治疗装置。该装置包括具有包括组织接触表面的近端和远端的壳体。壳体限定具有可定位在内部的能量输送装置的内部。能量递送装置包括至少一个具有组织穿透远端的电极，并被构造成从内部前进到目标组织部位以限定消融体积。一个前进装置耦合到能量输送装置，并被配置成使该至少一个电极前进。将至少一个电极推进到组织表面下方的选定的部署深度，同时避免关键结构。能量从能量输送装置输送。在组织表面下方的受控深度处产生消融体积，以响应于部署深度，同时最小化对关键结构的损伤。

3. 发明授权

US08216224B2 Tissue surface treatment apparatus and method 有权
标题翻译：组织表面处理装置及方法
公开(公告)号：US08216224B2
公开(公告)日：2012-07-10
申请号：US11893911
申请日：2007-08-17
申请人： David L. Morris , Steve A. Daniel , Daniel J. Balbierz
发明人： David L. Morris , Steve A. Daniel , Daniel J. Balbierz
IPC分类号： A61B18/14
CPC分类号： A61M25/1002 , A61B18/1477 , A61B2018/00011 , A61B2018/00017 , A61B2018/00029 , A61B2018/00291 , A61B2018/143 , A61B2018/1475 , A61M2025/0085
摘要： A method of controlling ablation volume depth includes providing a treatment apparatus. The apparatus comprises a housing having a proximal and distal end including a tissue contacting surface. The housing defines an interior with an energy delivery device positionable in the interior. The energy delivery device includes at least one electrode with a tissue penetrating distal end and is configured to be advanced from the interior into a target tissue site to define an ablation volume. An advancement device is coupled to the energy delivery device and is configured to advance the at least one electrode. The at least one electrode is advanced to a selected deployment depth beneath a tissue surface while avoiding a critical structure. Energy is delivered from the energy delivery device. An ablation volume is created at a controlled depth below the tissue surface responsive to the deployment depth while minimizing injury to the critical structure.
摘要翻译：控制消融体积深度的方法包括提供治疗装置。该装置包括具有包括组织接触表面的近端和远端的壳体。壳体限定具有可定位在内部的能量输送装置的内部。能量递送装置包括至少一个具有组织穿透远端的电极，并被构造成从内部前进到目标组织部位以限定消融体积。一个前进装置耦合到能量输送装置，并被配置成使该至少一个电极前进。将至少一个电极推进到组织表面下方的选定的部署深度，同时避免关键结构。能量从能量输送装置输送。在组织表面下方的受控深度处产生消融体积，以响应于部署深度，同时最小化对关键结构的损伤。

4. 发明授权

US07625371B2 Tissue surface treatment apparatus and method 失效
标题翻译：组织表面处理装置及方法
公开(公告)号：US07625371B2
公开(公告)日：2009-12-01
申请号：US11034435
申请日：2005-01-11
申请人： David L. Morris , Steven A. Daniel , Daniel J. Balbierz
发明人： David L. Morris , Steven A. Daniel , Daniel J. Balbierz
IPC分类号： A61B18/18
CPC分类号： A61M25/1002 , A61B18/1477 , A61B2018/00011 , A61B2018/00017 , A61B2018/00029 , A61B2018/00291 , A61B2018/143 , A61B2018/1475 , A61M2025/0085
摘要： A tissue surface treatment apparatus includes a housing having a proximal end, a distal end including a tissue contacting surface, an interior defined by the housing and a handpiece coupled to the housing. The contactinc surface has a plurality of apertures. An energy delivery device including an electrode is positionable in the housing interior. The electrode includes a tissue penetrating distal end in substantial alignment with an aperture. The electrode is configured to be advanced from the housing interior through the aperture and into a target tissue site to define an ablation volume at least partly bounded by a tissue surface. An advancement device is coupled to the energy delivery device and is at least partly positionable within at least one of the housing or the handpiece. The advancement device is configured to advance the electrode from the housing interior into the target tissue site and withdrawal the electrode into the housing interior. A cable is coupled to the housing or the energy delivery device and is configured to be coupled to an energy source.
摘要翻译：组织表面处理设备包括具有近端，远端包括组织接触表面的壳体，由壳体限定的内部和联接到壳体的手持件。触点表面具有多个孔。包括电极的能量输送装置可定位在壳体内部。电极包括与孔基本对准的穿透远端的组织。电极被配置为从壳体内部通过孔推进到目标组织部位以限定至少部分地由组织表面限定的消融体积。进给装置联接到能量输送装置，并且至少部分地可定位在壳体或手持件中的至少一个中。推进装置被配置为将电极从壳体内部推进到目标组织部位并将电极抽出到壳体内部。电缆耦合到壳体或能量输送装置，并且被配置为耦合到能量源。

5. 发明授权

US07422586B2 Tissue surface treatment apparatus and method 有权
标题翻译：组织表面处理装置及方法
公开(公告)号：US07422586B2
公开(公告)日：2008-09-09
申请号：US09797409
申请日：2001-02-28
申请人： David L. Morris , Steven A. Daniel , Daniel J. Balbierz
发明人： David L. Morris , Steven A. Daniel , Daniel J. Balbierz
IPC分类号： A61B18/18
CPC分类号： A61M25/1002 , A61B18/1477 , A61B2018/00011 , A61B2018/00017 , A61B2018/00029 , A61B2018/00291 , A61B2018/143 , A61B2018/1475 , A61M2025/0085
摘要： A tissue surface reatment apparatus includes a housing having a proximal end, a distal end including a tissue contacting surface, an interior defined by the housing and a handpiece coupled to the housing. The contactine surface has a plurality of apertures. An energy delivery device including an electrode is positionable in the housing interior. The electrode includes a tissue penetrating distal end in substantial alignment with an aperture. The electrode is configured to be advanced from the housing interior through the aperture and into a target tissue site to define an ablation volume at least partly bounded by a tissue surface. An advancement device is coupled to the energy deliveru device and is at least partly positionable within at least one of the housing or the handpiece. The advancement device is configured to advance the electrode fdro the housing interior into the target tissuesite and withdrawal the electrode into the housing interior. A cable is coupled to the housing or the energy delivery device and is configured to be coupled to an energy source.
摘要翻译：组织表面恢复装置包括具有近端，远端包括组织接触表面的壳体，由壳体限定的内部和联接到壳体的手持件。接触面具有多个孔。包括电极的能量输送装置可定位在壳体内部。电极包括与孔基本对准的穿透远端的组织。电极被配置为从壳体内部通过孔推进到目标组织部位以限定至少部分地由组织表面限定的消融体积。进给装置联接到能量输送装置，并且至少部分地可定位在壳体或手持件中的至少一个中。推进装置被配置为使电极将壳体内部推进到目标组织中并将电极撤回到壳体内部。电缆耦合到壳体或能量输送装置，并且被配置为耦合到能量源。

6. 发明授权

US07160296B2 Tissue ablation apparatus and method 有权
标题翻译：组织消融装置及方法
公开(公告)号：US07160296B2
公开(公告)日：2007-01-09
申请号：US10142713
申请日：2002-05-10
申请人： Rob Pearson , Steve A. Daniel , Daniel J. Balbierz , Kee S. Lee , Jessica Liang , Martha Getaneh
发明人： Rob Pearson , Steve A. Daniel , Daniel J. Balbierz , Kee S. Lee , Jessica Liang , Martha Getaneh
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B2018/0016 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00714 , A61B2018/00791 , A61B2018/00797 , A61B2018/00875 , A61B2018/143 , A61B2018/1472 , A61B2018/1475
摘要： A tissue-ablation method and apparatus are disclosed. The apparatus includes a plurality of RF ablation electrodes, and a plurality of sensor elements, each movable from retracted to deployed positions in a tissue to be ablated. A control device in the apparatus is operatively connected to the electrodes for supplying an RF power to the electrodes, to produce tissue ablation that advances from individual-electrode ablation regions to fill a combined-electrode ablation volume. The control device is operatively connected to the sensor elements for determining the extent of ablation in the regions of the sensor elements. The supply of RF power to the electrodes can thus be regulated to control the level and extent of tissue ablation throughout the combined-electrode volume. The electrodes are preferably hollow-needle electrodes through which liquid can be infused into the tissue, also under the control of the control unit, to modulate and optimize tissue ablation.
摘要翻译：公开了组织消融方法和装置。该装置包括多个RF消融电极和多个传感器元件，每个传感器元件可从收缩的组织中的缩回到展开位置移动以进行烧蚀。设备中的控制装置可操作地连接到电极，以向电极提供RF功率，以产生从单个电极消融区域前进以填充组合电极消融体积的组织消融。控制装置可操作地连接到传感器元件，以确定传感器元件区域中的消融程度。因此，可以调节对电极的RF功率的供应以控制整个组合电极体积中的组织消融的水平和程度。电极优选是中空针电极，液体也可以在控制单元的控制下输注到组织中，以调节和优化组织消融。

7. 发明授权

US09055942B2 Endoscopic plication devices and methods 有权
标题翻译：内镜矫治装置及方法
公开(公告)号：US09055942B2
公开(公告)日：2015-06-16
申请号：US11542457
申请日：2006-10-03
申请人： Daniel J. Balbierz , Dave Cole , Samuel T. Crews , Brett Swope , Andrew Smith , John Lunsford , Fiona Sander
发明人： Daniel J. Balbierz , Dave Cole , Samuel T. Crews , Brett Swope , Andrew Smith , John Lunsford , Fiona Sander
IPC分类号： A61B17/08 , A61B17/068 , A61B17/072 , A61B17/115 , A61B17/128 , A61B17/02 , A61B17/00 , A61B17/30
CPC分类号： A61B17/1155 , A61B17/0218 , A61B17/068 , A61B17/072 , A61B17/07292 , A61B17/1114 , A61B17/115 , A61B17/1285 , A61B2017/00535 , A61B2017/00827 , A61B2017/07214 , A61B2017/07228 , A61B2017/1139 , A61B2017/1157 , A61B2017/306 , A61F5/0036
摘要： Endoscopic plicators are passed transorally into the stomach and used to plicate stomach tissue by engaging tissue from inside of the stomach and drawing it inwardly. The tissue is drawn inwardly into a vacuum chamber, causing sections of serosal tissue on the exterior of the stomach to be positioned facing one another. The plicators allow the opposed sections of tissue to be moved into contact with one another, and preferably deliver sutures, staples or other means for maintaining contact between the tissue sections at least until serosal bonds form between them. Each of these steps may be performed wholly from the inside of the stomach and thus can eliminate the need for any surgical or laparscopic intervention. After one or more plications is formed, medical devices may be coupled to the plication(s) for retention within the stomach.
摘要翻译：将内窥镜矫正器经腹部通入胃中，并用于通过从胃内部接合组织并将其向内抽吸来摧毁胃组织。将组织向内拉入真空室，使得胃外部的浆膜组织部分彼此相对定位。调节器允许组织的相对部分彼此移动接触，并且优选地递送缝合线，缝钉或其它装置，用于保持组织切片之间的接触，至少在它们之间形成浆膜粘结。这些步骤中的每一个可以完全从胃内进行，因此可以消除对任何手术或腹腔镜干预的需要。在形成一个或多个脓肿之后，医疗装置可以连接到脓液以保持在胃中。

8. 发明申请

US20110319924A1 Gastric Space Occupier Systems And Methods Of Use 有权
标题翻译：胃空间占用系统和使用方法
公开(公告)号：US20110319924A1
公开(公告)日：2011-12-29
申请号：US13224233
申请日：2011-09-01
申请人： David Cole , Samuel T. Crews , Bretton Swope , Andrew Smith , John Lunsford , Daniel J. Balbierz
发明人： David Cole , Samuel T. Crews , Bretton Swope , Andrew Smith , John Lunsford , Daniel J. Balbierz
IPC分类号： A61F2/04
CPC分类号： A61F5/0036 , A61F5/003
摘要： Systems for controlling obesity utilize a number of space occupiers positioned in the stomach to reduce the effective volume of the stomach. Such arrangements provides sufficient stomach volume consumption to induce weight loss, but enable use of space occupiers that are proportioned to minimize the threat of obstruction even if they should migrate into the intestine. In general, numerous small volume space occupiers are placed in the stomach such that the total volume equals or exceeds the single volume of prior art single unit space occupiers. However, each individual space occupier is proportioned so that it will pass without obstruction if it moves into the intestine.
摘要翻译：用于控制肥胖的系统利用位于胃中的多个空间占用者来减少胃的有效体积。这种布置提供足够的胃体积消耗以引起体重减轻，但是能够使用成比例的空间占用者，以尽量减少阻塞的威胁，即使它们应该迁移到肠中。通常，许多小容量空间占用者被放置在胃中，使得总体积等于或超过现有技术的单个单位空间占用者的单个体积。然而，每个单独的空间占有者是成比例的，以便如果它进入肠道，它将不会阻塞。

9. 发明授权

US07344533B2 Impedance controlled tissue ablation apparatus and method 有权
标题翻译：阻抗控制组织消融装置及方法
公开(公告)号：US07344533B2
公开(公告)日：2008-03-18
申请号：US10260187
申请日：2002-09-28
申请人： Robert M. Pearson , Steven A. Daniel , Daniel J. Balbierz , Theodore C. Johnson , Zia Yassinzadeh
发明人： Robert M. Pearson , Steven A. Daniel , Daniel J. Balbierz , Theodore C. Johnson , Zia Yassinzadeh
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B2018/00011 , A61B2018/00083 , A61B2018/00196 , A61B2018/00577 , A61B2018/00702 , A61B2018/00726 , A61B2018/00738 , A61B2018/00744 , A61B2018/0075 , A61B2018/00755 , A61B2018/00761 , A61B2018/00791 , A61B2018/00869 , A61B2018/00875 , A61B2018/124 , A61B2018/1253 , A61B2018/1425 , A61B2018/143 , A61B2018/1432 , A61B2218/002
摘要： A method and apparatus for carrying our thermal ablation of target tissue is disclosed. The apparatus includes an RF ablation device having a multi-electrode electrode assembly designed to be deployed in target tissue, defining a selected-volume tissue region to be ablated, and having infusion channels for infusing a liquid into the target tissue during the ablation process. A control unit in the apparatus is operably connected to an RF energy source, for controlling the RF power level supplied to the electrodes, and to an infusion device, for controlling the rate of infusion of a liquid through the device into the tissue. During both electrode deployment and tissue ablation, impedance and or temperature measurements made within the tissue are used to control the RF source and infusion device, for optimizing the time and extent of tissue ablation.
摘要翻译：公开了一种用于携带我们的靶组织热消融的方法和装置。该装置包括RF消融装置，其具有设计成部署在靶组织中的多电极电极组件，限定要消融的选择体积的组织区域，并且具有用于在消融过程期间将液体注入靶组织的输注通道。装置中的控制单元可操作地连接到RF能量源，用于控制提供给电极的RF功率水平，以及用于控制通过装置将液体输入到组织中的输注装置。在电极部署和组织消融期间，组织内进行的阻抗和/或温度测量用于控制RF源和输注装置，以优化组织消融的时间和程度。

10. 发明授权

US07108696B2 Bone-treatment instrument and method 有权
公开(公告)号：US07108696B2
公开(公告)日：2006-09-19
申请号：US10668433
申请日：2003-09-22
申请人： Steven A. Daniel , Daniel J. Balbierz , Robert D. Russell , Robert Pearson , Andres Tamayo , Takehito Jimbo , Karen Frischmeyer
发明人： Steven A. Daniel , Daniel J. Balbierz , Robert D. Russell , Robert Pearson , Andres Tamayo , Takehito Jimbo , Karen Frischmeyer
IPC分类号： A61B18/18 , A61B17/50
CPC分类号： A61B18/1477 , A61B2017/003 , A61B2018/00029 , A61B2018/00083 , A61B2018/00142 , A61B2018/00654 , A61B2018/00755 , A61B2018/00797 , A61B2018/00875 , A61B2018/1435 , A61B2090/3925 , A61B2218/002 , A61M5/142 , G06F19/00
摘要： Ablation devices and associated methods are provided for use in palliative treatment of a bone tumor on or in a compact bone region. The bone treatment devices include an elongate probe having a distal end. A proximal end of the probe supports placement in a location at or adjacent to the bone tumor. Electrodes are carried within the probe for deployment from the distal end into the bone tumor. The electrodes may be shapable to create, upon deployment, an array of electrodes that defines a geometric area within the bone tumor. Application of energy, for example energy from a radio frequency (RF) source, to the area of the bone tumor via the electrodes destroys at least a portion of the nerve receptors located in or adjacent to the tumor and produces a reduction in pain associated with the bone tumor. Liquid, such as a polymer in liquid form, may be injected through an electrode needle, with electrode heating being employed to allow introduction of the polymer solution through the needle and/or hardening at the site of injection.

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