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1. 发明授权

US06566469B1 Enzyme-mediated polymerization methods and products 失效
标题翻译：酶介导的聚合方法和产品
公开(公告)号：US06566469B1
公开(公告)日：2003-05-20
申请号：US09602649
申请日：2000-06-22
申请人： David Kaplan , Graham Swift , Richard A. Gross , Bhanu Kalra
发明人： David Kaplan , Graham Swift , Richard A. Gross , Bhanu Kalra
IPC分类号： C08F430
CPC分类号： C12P1/00
摘要： A method for polymerization of substituted ethylene monomers in an enzyme-mediated process is disclosed. The reaction proceeds under mild conditions with a wide variety of monomers, and is capable of producing stereoregular polymers. In certain embodiments, no organic solvent is necessary.
摘要翻译：公开了在酶介导的方法中聚合取代的乙烯单体的方法。该反应在温和条件下与各种各样的单体进行，并且能够产生立体有规聚合物。在某些实施方案中，不需要有机溶剂。

2. 发明授权

US5981743A Cyclic ester ring-opened oligomers and methods of preparation 失效
标题翻译：环酯开环低聚物及其制备方法
公开(公告)号：US5981743A
公开(公告)日：1999-11-09
申请号：US828432
申请日：1997-03-28
申请人： Richard A. Gross , Kirpal Bisht , David Kaplan , Graham Swift , Fang Deng
发明人： Richard A. Gross , Kirpal Bisht , David Kaplan , Graham Swift , Fang Deng
IPC分类号： C07H13/04 , C07H1/00 , C07G17/00
CPC分类号： C07H13/04
摘要： An oligomer composed of a carbohydrate head group and an oligomer chain is disclosed. Methods for increasing the oligomerization rates of lactones and cyclic carbonates are also disclosed.
摘要翻译：公开了由碳水化合物头基和低聚物链构成的低聚物。还公开了提高内酯和环状碳酸酯的低聚速率的方法。

3. 发明授权

US4096863A Band for anchoring a cathetor or any other tubular device to the body 失效
标题翻译：用于将导管或任何其它管状装置锚定到身体的带
公开(公告)号：US4096863A
公开(公告)日：1978-06-27
申请号：US745804
申请日：1976-11-29
申请人： David Kaplan , Irving Brezack , Nathan H. Young, deceased , by David Kaplan, executor , by Irving Brezack, executor , Herbert H. Wapner
发明人： David Kaplan , Irving Brezack , Nathan H. Young, deceased , by David Kaplan, executor , by Irving Brezack, executor , Herbert H. Wapner
IPC分类号： A61M25/02
CPC分类号： A61M25/02 , A61M2025/0206 , A61M2025/026 , Y10S128/26 , Y10T24/14
摘要： A band for securing a catheter or similar device to a limb of a human comprising a stretchable primary strap adapted to encircle the limb. A part of the strap is made of a soft looped fabric and the strap also carries a male Velcro-type fastening material which cooperates with the looped fabric to enable the strap to be secured in place about the limb. A secondary strap made of a flexible material is secured at one end intermediate the ends of the primary strap. That end of the secondary strap also carries a clip having an eye. The other end of the secondary strap, made of a male Velcro-type fastening material, may be threaded through the eye of the clip and engage the looped fabric so that the secondary strap forms a closed loop for encircling the catheter or similar device and holding it securely in place on the limb.
摘要翻译：用于将导管或类似装置固定到人的肢体的带，包括适于环绕肢体的可拉伸主带。表带的一部分由柔软的环状织物制成，并且表带还带有与环形织物配合的男性Velcro型紧固材料，以使带能够围绕肢体固定就位。由柔性材料制成的次级带固定在主带的端部之间的一端。次级带的端部还带有具有眼睛的夹子。辅助带子的另一端由男性魔术贴型紧固材料制成，可以穿过夹子的眼睛并与环形织物接合，使得次级带形成用于环绕导管或类似装置的闭环，并且保持它牢固地固定在肢体上。

4. 发明授权

US09286233B2 Oldest operation translation look-aside buffer 有权
标题翻译：最旧的操作翻译后备缓冲区
公开(公告)号：US09286233B2
公开(公告)日：2016-03-15
申请号：US13599269
申请日：2012-08-30
申请人： David Kaplan , John M. King
发明人： David Kaplan , John M. King
IPC分类号： G06F13/00 , G06F12/10 , G06F9/30 , G06F12/08
CPC分类号： G06F12/1027 , G06F9/30 , G06F9/3824 , G06F12/0888
摘要： A method is provided for dispatching a load operation to a processing device and determining that the operation is the oldest load operation. The method also includes executing the operation in response to determining the operation is the oldest load operation. Computer readable storage media for performing the method are also provided. An apparatus is provided that includes a translation look-aside buffer (TLB) content addressable memory (CAM), and includes an oldest operation storage buffer operationally coupled to the TLB CAM. The apparatus also includes an output multiplexor operationally coupled to the TLB CAM and to the oldest operation storage buffer. Computer readable storage media for adapting a fabrication facility to manufacture the apparatus are also provided.
摘要翻译：提供了一种用于将加载操作调度到处理设备并确定该操作是最早的加载操作的方法。该方法还包括响应于确定操作是最旧的加载操作来执行操作。还提供了用于执行该方法的计算机可读存储介质。提供了包括翻译后备缓冲器（TLB）内容可寻址存储器（CAM）的装置，并且包括可操作地耦合到TLB CAM的最旧的操作存储缓冲器。该装置还包括可操作地耦合到TLB CAM和最旧的操作存储缓冲器的输出多路复用器。还提供了用于使制造设备适应制造设备的计算机可读存储介质。

5. 发明申请

US20150203039A1 AUTOMATIC REAR-VIEW MIRROR ADJUSTMENTS 审中-公开
标题翻译：自动后视镜调整
公开(公告)号：US20150203039A1
公开(公告)日：2015-07-23
申请号：US14158282
申请日：2014-01-17
申请人： David Kaplan , Tomer Rider , Aviv Ron , Shahar Taite
发明人： David Kaplan , Tomer Rider , Aviv Ron , Shahar Taite
IPC分类号： B60R1/02
CPC分类号： B60R1/025
摘要： Systems and methods may provide for identifying a first position of a rear-view mirror, wherein the first position provides a target field of view. Additionally, a second position may be determined for the rear-view mirror in response to a travel related tilt of the rear-view mirror and the rear-view mirror may be automatically adjusted to the second position, wherein the second position provides the target field of view after the travel related tilt. In one example, the travel related tilt is detected based on one or more sensor signals.
摘要翻译：系统和方法可以提供用于识别后视镜的第一位置，其中第一位置提供目标视场。此外，可以响应于后视镜的行进相关倾斜来确定后视镜的第二位置，并且后视镜可以被自动调整到第二位置，其中第二位置提供目标场的旅行相关倾斜后。在一个示例中，基于一个或多个传感器信号来检测行进相关的倾斜。

6. 发明授权

US08887012B2 Method and apparatus for saving and restoring soft repair data 有权
标题翻译：保存和恢复软修复数据的方法和装置
公开(公告)号：US08887012B2
公开(公告)日：2014-11-11
申请号：US12862129
申请日：2010-08-24
申请人： Bill K. Kwan , Atchyuth K. Gorti , Norm Hack , David Kaplan
发明人： Bill K. Kwan , Atchyuth K. Gorti , Norm Hack , David Kaplan
IPC分类号： G06F11/00 , G11C29/44 , G11C29/00 , G11C29/04
CPC分类号： G11C29/74 , G11C29/4401 , G11C2029/0409 , G11C2029/4402
摘要： The present invention provides a method and apparatus for saving and restoring soft repair information. One embodiment of the method includes storing soft repair information for one or more cache arrays implemented in a processor core in a memory element outside of the processor core in response to determining that a voltage supply to the processor core is to be disconnected.
摘要翻译：本发明提供了一种用于保存和恢复软修复信息的方法和装置。所述方法的一个实施例是响应于确定要对所述处理器核心的电压供应被断开而将针对在处理器核心中实施的处理器核心的软修复信息存储在处理器核心外的存储器元件中。

7. 发明申请

US20140187148A1 NEAR FIELD COMMUNICATION METHOD AND APPARATUS USING SENSOR CONTEXT 审中-公开
标题翻译：近场通信方法和使用传感器语境的设备
公开(公告)号：US20140187148A1
公开(公告)日：2014-07-03
申请号：US13727848
申请日：2012-12-27
申请人： Shahar Taite , David Kaplan , Israel Robotnick , Nurit Rosenbaum
发明人： Shahar Taite , David Kaplan , Israel Robotnick , Nurit Rosenbaum
IPC分类号： H04B5/00
CPC分类号： H04M1/7253 , G06F3/014 , G06F3/017 , G06F3/0346 , G06F3/04883 , H04M2250/04 , H04M2250/12
摘要： A sensor input into a first near field communication (NFC) device, such as an accelerometer input resulting from a rapid motion of the first NFC device to the right, is associated with a function of a second NFC device, such as a zoom function. The first NFC device is brought into proximity to a second NFC device and an NFC operation is launched. If the sensor input into the first NFC device is detected during a time window including the NFC launch time, the first NFC device communicates instructions to the second NFC device to execute the function, and the function is executed by the second NFC device.
摘要翻译：将第一近场通信（NFC）设备的传感器输入与诸如缩放功能的第二NFC设备的功能相关联，诸如由第一NFC设备向右移动的加速度计输入。将第一NFC设备接近第二NFC设备，并且启动NFC操作。如果在包括NFC启动时间的时间窗口期间检测到输入到第一NFC设备的传感器，则第一NFC设备将指令传送到第二NFC设备以执行该功能，并且该功能由第二NFC设备执行。

8. 发明申请

US20120121820A1 FABRICATION OF SILK FIBROIN PHOTONIC STRUCTURES BY NANOCONTACT IMPRINTING 有权
标题翻译：通过纳米压印制造丝光纤光电结构
公开(公告)号：US20120121820A1
公开(公告)日：2012-05-17
申请号：US12741066
申请日：2008-11-05
申请人： David Kaplan , Fiorenzo Omenetto , Brian Lawrence , Mark Cronin-Golomb , Irene Georgakoudi , Luca Dal Negro
发明人： David Kaplan , Fiorenzo Omenetto , Brian Lawrence , Mark Cronin-Golomb , Irene Georgakoudi , Luca Dal Negro
IPC分类号： C08J7/18 , B29C59/16
CPC分类号： G03F7/0002 , B29D11/00 , B29D11/00346 , B82Y10/00 , B82Y20/00 , B82Y40/00 , C07K14/435 , G02B6/1225
摘要： A method of manufacturing a nanopatterned biophotonic structure includes forming a customized nanopattern mask on a substrate using E-beam lithography, providing a biopolymer matrix solution, depositing the biopolymer matrix solution on the substrate, and drying the biopolymer matrix solution to form a solidified biopolymer film. A surface of the film is formed with the nanopattern mask, or a nanopattern is machined directly on a surface of the film using E-beam lithograpy such that the biopolymer film exhibits a spectral signature corresponding to the E-beam lithograpy nanopattern. The resulting bio-compatible nanopatterned biophotonic structures may be made from silk, may be biodegradable, and may be bio-sensing devices. The biophotonic structures may employ nanopatterned masks based on non-periodic photonic lattices, and the biophotonic structures may be designed with specific spectral signatures for use in probing biological substances, including displaying optical activity in the form of opalescence.
摘要翻译：制造纳米图案生物光子结构的方法包括使用电子束光刻在基底上形成定制的纳米图案掩模，提供生物聚合物基质溶液，将生物聚合物基质溶液沉积在基材上，以及干燥生物聚合物基质溶液以形成固化的生物聚合物膜。用纳米图案掩模形成膜的表面，或者使用电子束光刻直接在膜的表面上加工纳米图案，使得生物聚合物膜显示对应于电子束光刻纳米图案的光谱特征。所得的生物相容纳米图案的生物光子结构可以由丝制成，可以是可生物降解的，并且可以是生物感测装置。生物光子结构可以使用基于非周期性光子晶格的纳米图案掩模，并且生物光子结构可以被设计成用于探测生物物质的特定光谱特征，包括以乳光的形式显示光学活性。

9. 外观设计

USD653764S1 Thermal cycling system for biological assays 有权
标题翻译：用于生物测定的热循环系统
公开(公告)号：USD653764S1
公开(公告)日：2012-02-07
申请号：US29358668
申请日：2010-03-30
申请人： Judy Macemon , David Kaplan , Adrian Fawcett , Kevin Simmons , Andrew Zoolakis
设计人： Judy Macemon , David Kaplan , Adrian Fawcett , Kevin Simmons , Andrew Zoolakis

10. 发明申请

US20110301105A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS 有权
标题翻译：用于增殖细胞的组合物和相关方法
公开(公告)号：US20110301105A1
公开(公告)日：2011-12-08
申请号：US13075647
申请日：2011-03-30
申请人： Freda Miller , David Kaplan , Kristen Smith , Maryline Paris , Sibel Naska
发明人： Freda Miller , David Kaplan , Kristen Smith , Maryline Paris , Sibel Naska
IPC分类号： A61K31/7028 , C12N5/09 , C12Q1/02 , A61K31/522 , A61K31/5575 , A61K31/357 , A61K31/498 , A61K31/675 , A61K31/4168 , A61K31/352 , A61K31/382 , A61K31/40 , A61K31/4355 , A61K31/09 , A61K31/57 , A61K31/366 , A61K31/14 , A61K31/5375 , A61K31/7034 , A61K31/155 , A61K31/4745 , A61P17/00 , A61P17/02 , C12N5/071
CPC分类号： A61K31/5575 , A61K8/365 , A61K8/416 , A61K8/49 , A61K8/498 , A61K8/64 , A61K8/981 , A61K31/09 , A61K31/14 , A61K31/155 , A61K31/352 , A61K31/353 , A61K31/357 , A61K31/366 , A61K31/382 , A61K31/40 , A61K31/4168 , A61K31/4355 , A61K31/4745 , A61K31/498 , A61K31/522 , A61K31/5375 , A61K31/57 , A61K31/675 , A61K31/7028 , A61K31/7034 , A61K35/36 , A61K38/1808 , A61K38/1825 , A61K45/06 , A61Q7/00 , A61Q19/00 , A61Q19/08 , G01N33/5044 , G01N33/5073 , G01N33/6893 , G01N2500/00 , G01N2800/20 , A61K2300/00
摘要： We have discovered that p63 inhibition results in increased cellular proliferation. We have also performed a screen for agents capable of increasing cellular proliferation, (e.g., of stem cells such as skin-derived precursors (SKPs)). The invention therefore invention provides compositions, methods, and kits for increasing proliferation of cells, using compounds that decrease p63 expression or activity or using the compounds described herein. The invention also features methods of using these compounds for increasing hair growth, improving skin health, or promoting skin repair in a subject.
摘要翻译：我们已经发现p63抑制导致细胞增殖增加。我们还对能够增加细胞增殖的试剂（例如干细胞如皮肤衍生的前体（SKP））进行筛选。因此，本发明提供了使用减少p63表达或活性的化合物或使用本文所述的化合物来增加细胞增殖的组合物，方法和试剂盒。本发明还涉及使用这些化合物来增加受试者的毛发生长，改善皮肤健康或促进皮肤修复的方法。

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