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1. 发明申请

US20120186999A1 ELECTROCHEMICAL SENSOR 审中-公开
标题翻译：电化学传感器
公开(公告)号：US20120186999A1
公开(公告)日：2012-07-26
申请号：US13266442
申请日：2010-04-27
申请人： David John Walton , Xiaobo Ji , Craig Edward Banks
发明人： David John Walton , Xiaobo Ji , Craig Edward Banks
IPC分类号： G01N27/30 , G01N33/50 , B82Y30/00
CPC分类号： G01N33/497 , G01N2033/4975 , G01N2800/065
摘要： The invention provides an electrochemical sensor comprising an electrode assembly which comprises at least two electrodes, one of the electrodes comprising a metal species capable of catalysing the oxidation of hydrogen and/or methane. The sensor may be used in the detection and quantification of hydrogen and/or methane in exhaled breath, for example as a means of diagnosing lactose malabsorption or lactose intolerance.
摘要翻译：本发明提供一种电化学传感器，其包括电极组件，该电极组件包括至少两个电极，其中一个电极包括能够催化氢和/或甲烷氧化的金属物质。传感器可用于呼出呼气中氢和/或甲烷的检测和定量，例如作为诊断乳糖吸收不良或乳糖不耐症的手段。

2. 发明申请

US20100288651A1 MULTI-WALLED CARBON NANOTUBE SENSOR COMPRISING INTERCALATING SPECIES AND METHOD OF DETECTION 审中-公开
标题翻译：包含交联物种的多壁碳纳米管传感器和检测方法
公开(公告)号：US20100288651A1
公开(公告)日：2010-11-18
申请号：US12293712
申请日：2007-03-20
申请人： Richard Guy Compton , Craig Edward Banks , Xiaobo Ji
发明人： Richard Guy Compton , Craig Edward Banks , Xiaobo Ji
IPC分类号： G01N27/26 , G01N27/30 , B32B9/00 , B82B1/00
CPC分类号： G01N27/308 , B82Y15/00 , G01N27/48 , G01N33/0054 , Y02A50/246 , Y10T428/2918
摘要： There is provided a method of detecting an analyte in a sample, which comprises the steps of contacting the sample with a working electrode in the presence of an electrolyte and determining the electrochemical response of the working electrode to the sample, wherein the working electrode comprises a multi-walled carbon nanotube (MWCNT) and wherein detection takes place in the presence of a species which is capable of forming an intercalation compound with a carbon host material. Electrochemical sensors and compositions suitable for use in said method are also provided.
摘要翻译：提供了一种检测样品中的分析物的方法，其包括以下步骤：在电解液存在下使样品与工作电极接触并确定工作电极对样品的电化学响应，其中工作电极包括多壁碳纳米管（MWCNT），并且其中检测在能够与碳主体材料形成插层化合物的物质存在下进行。还提供适用于所述方法的电化学传感器和组合物。

3. 发明申请

US20110168576A1 ELECTROCHEMICAL ASSAY 有权
标题翻译：电化学测定
公开(公告)号：US20110168576A1
公开(公告)日：2011-07-14
申请号：US12989412
申请日：2009-04-24
申请人： Dimitrios Konstantinos Kampouris , Rashid Olukayoee Kadara , Patrick Robinson Huddleston , Craig Edward Banks
发明人： Dimitrios Konstantinos Kampouris , Rashid Olukayoee Kadara , Patrick Robinson Huddleston , Craig Edward Banks
IPC分类号： G01N27/48 , G01N27/416 , G01N33/487
CPC分类号： G01N33/48714 , G01N27/302
摘要： The invention provides an electrochemical assay for a phenol analyte in a body fluid sample wherein said sample, or fluid therefrom, is contacted with the working electrode of an electrode assembly comprising a working electrode, a counter-electrode, a voltage supply to said working and counter-electrodes and a current meter for determining the current between said working and counter-electrodes, and wherein a first compound capable of reversible oxidation and reduction is disposed at said working electrode, said first compound being capable in either an oxidized or a reduced form of binding to said phenol analyte, characterized in that said first compound in its oxidized or reduced form comprises a group of structure I R1-NH—C*—(C*—C*)n—C*-QR′ (I) (where n is 0 or 1; Q is 0, S, NH or NR′; C*—(C*—C*)n—C* is a two or four carbon string in a conjugated delocalised electron system optionally substituted by a group comprising R; R is an electron-donating or withdrawing substituent; and R′ is H or a group R, at least one group R′ being a group R).
摘要翻译：本发明提供了体液样品中酚分析物的电化学测定，其中所述样品或其流体与包括工作电极，对电极，对所述工作的电压供应的电极组件的工作电极接触，以及对电极和用于确定所述工作电极和对电极之间的电流的电流计，并且其中能够可逆地氧化和还原的第一化合物设置在所述工作电极处，所述第一化合物能够以氧化或还原的形式其特征在于所述第一化合物以其氧化或还原形式包含结构I R1-NH-C * - （C * -C *）n-C * -QR'（I）（其中n为0或1; Q为0，S，NH或NR'; C * - （C * -C *）n -C *为任选被基团取代的共轭离域电子系统中的两个或四个碳原子包括R; R是给电子或取出的Su 并且R'是H或基团R，至少一个基团R'是基团R）。

4. 发明授权

US08877038B2 Electrochemical assay 有权
标题翻译：电化学测定
公开(公告)号：US08877038B2
公开(公告)日：2014-11-04
申请号：US12989412
申请日：2009-04-24
申请人： Dimitrios Konstantinos Kampouris , Rashid Olukayoee Kadara , Patrick Robinson Huddleston , Craig Edward Banks
发明人： Dimitrios Konstantinos Kampouris , Rashid Olukayoee Kadara , Patrick Robinson Huddleston , Craig Edward Banks
IPC分类号： G01N27/327 , G01N33/487 , G01N27/30
CPC分类号： G01N33/48714 , G01N27/302
摘要： The invention provides an electrochemical assay for a phenol analyte in a body fluid sample wherein said sample, or fluid therefrom, is contacted with the working electrode of an electrode assembly comprising a working electrode, a counter-electrode, a voltage supply to said working and counter-electrodes and a current meter for determining the current between said working and counter-electrodes, and wherein a first compound capable of reversible oxidation and reduction is disposed at said working electrode, said first compound being capable in either an oxidized or a reduced form of binding to said phenol analyte, characterized in that said first compound in its oxidized or reduced form comprises a group of structure I R1-NH—C*—(C*—C*)n—C*-QR′ (I) (where n is 0 or 1; Q is 0, S, NH or NR′; C*—(C*—C*)n—C* is a two or four carbon string in a conjugated delocalised electron system optionally substituted by a group comprising R; R is an electron-donating or withdrawing substituent; and R′ is H or a group R, at least one group R′ being a group R).
摘要翻译：本发明提供了体液样品中酚分析物的电化学测定，其中所述样品或其流体与包括工作电极，对电极，对所述工作的电压供应的电极组件的工作电极接触，以及对电极和用于确定所述工作电极和对电极之间的电流的电流计，并且其中能够可逆地氧化和还原的第一化合物设置在所述工作电极处，所述第一化合物能够以氧化或还原的形式其特征在于所述第一化合物以其氧化或还原形式包含结构I R1-NH-C * - （C * -C *）n-C * -QR'（I）（其中n为0或1; Q为0，S，NH或NR'; C * - （C * -C *）n -C *为任选被基团取代的共轭离域电子系统中的两个或四个碳原子包括R; R是给电子或取出的Su 并且R'是H或基团R，至少一个基团R'是基团R）。

5. 发明申请

US20090294298A1 Detection of Phenols 审中-公开
标题翻译：苯酚检测
公开(公告)号：US20090294298A1
公开(公告)日：2009-12-03
申请号：US11922265
申请日：2006-06-16
申请人： Richard Guy Compton , Craig Edward Banks
发明人： Richard Guy Compton , Craig Edward Banks
IPC分类号： C25B3/02 , G01N27/26 , G01N27/30 , C25B11/04
CPC分类号： G01N27/28 , G01N27/30 , G01N27/403 , G01N27/416 , G01N27/49 , G01N33/48714
摘要： According to the present invention, phenols may be detected using an electrochemical sensor comprising a final compound, a working electrode and an electrolyte in contact with the working electrode, wherein the first compound operatively undergoes a redox reaction at the working electrodes to form a second compound which operatively reacts in situ with the phenol, wherein said redox reaction has a detectable redox couple and wherein the sensor is adapted to determine the electrochemical response of the working electrode to the consumption of said second compound on reaction with the phenol. The phenol may be, for example, cannabinoid or a catechin compound.
摘要翻译：根据本发明，可以使用包含最终化合物，工作电极和与工作电极接触的电解质的电化学传感器检测酚，其中第一化合物在工作电极处可操作地进行氧化还原反应以形成第二化合物其与所述酚在原位操作地反应，其中所述氧化还原反应具有可检测的氧化还原对，并且其中所述传感器适于确定所述工作电极对与所述苯酚反应的所述第二化合物的消耗的电化学响应。酚可以是例如大麻素或儿茶素化合物。

6. 发明授权

US08785204B2 Methods of assaying for tetrahydrocannabinol 失效
标题翻译：四氢大麻酚测定方法
公开(公告)号：US08785204B2
公开(公告)日：2014-07-22
申请号：US13201446
申请日：2010-01-28
申请人： Dimitrios Konstantinos Kampouris , Patrick Robinson Huddleston , Craig Edward Banks
发明人： Dimitrios Konstantinos Kampouris , Patrick Robinson Huddleston , Craig Edward Banks
IPC分类号： G01N33/94 , G01N27/00
CPC分类号： G01N33/948
摘要： The invention provides a method of assaying for tetrahydrocannabinol in a body fluid. The method includes contacting a sample of body fluid with an imine capable of reacting with tetrahydrocannabinol to yield a quinone imine, and detecting the formation of a quinone imine, where the sample is contacted with the reagent compound at a pH of at least 10.5.
摘要翻译：本发明提供一种在体液中测定四氢大麻酚的方法。该方法包括使体液样品与能够与四氢大麻酚反应的亚胺接触以产生醌亚胺，并检测醌亚胺的形成，其中样品在至少10.5的pH下与试剂化合物接触。

7. 发明授权

US08541239B2 Assay method for detecting primary amines 失效
标题翻译：检测伯胺的测定方法
公开(公告)号：US08541239B2
公开(公告)日：2013-09-24
申请号：US13125286
申请日：2009-10-15
申请人： Dimitrios Konstantinos Kampouris , Patrick Robinson Huddleston , Craig Edward Banks
发明人： Dimitrios Konstantinos Kampouris , Patrick Robinson Huddleston , Craig Edward Banks
IPC分类号： G01N33/50 , G01N33/00
CPC分类号： G01N33/946 , G01N33/523
摘要： The invention provides an assay method for the detection of a primary amine analyze in an aqueous body fluid, which method comprises contacting a sample of said body fluid at a pH below 9.5 with a thiol and an unsaturated cis-dialdehyde and testing for the presence of a pyrrole reaction product.
摘要翻译：本发明提供了用于检测体液中的伯胺分析的测定方法，该方法包括使pH低于9.5的所述体液样品与硫醇和不饱和顺式二醛接触，并测试是否存在吡咯反应产物。

8. 发明申请

US20120122229A1 METHODS OF ASSAYING FOR TETRAHYDROCANNABINOL 失效
标题翻译：四氢萘啶醇的测定方法
公开(公告)号：US20120122229A1
公开(公告)日：2012-05-17
申请号：US13201446
申请日：2010-01-28
申请人： Dimitrios Konstantinos Kampouris , Patrick Robinson Huddleston , Craig Edward Banks
发明人： Dimitrios Konstantinos Kampouris , Patrick Robinson Huddleston , Craig Edward Banks
IPC分类号： G01N33/94 , B01L3/00
CPC分类号： G01N33/948
摘要： The invention provides a method of assaying for tetrahydrocannabinol in a body fluid, said method comprising contacting a sample of body fluid with an imine capable of reacting with tetrahydrocannabinol to yield a quinone imine, and detecting the formation of a quinone imine, characterised in that said sample is contacted with said reagent compound at a pH of at least 10.5.
摘要翻译：本发明提供一种测定体液中四氢大麻酚的方法，所述方法包括使体液样品与能够与四氢大麻酚反应的亚胺接触以产生醌亚胺，并检测醌亚胺的形成，其特征在于所述样品与所述试剂化合物在至少10.5的pH下接触。

9. 发明申请

US20110312100A1 ASSAY METHOD FOR DETECTING PRIMARY AMINES 失效
标题翻译：用于检测主要氨基酸的测定方法
公开(公告)号：US20110312100A1
公开(公告)日：2011-12-22
申请号：US13125286
申请日：2009-10-15
申请人： Dimitrios Konstantinos Kampouris , Patrick Robinson Huddleston , Craig Edward Banks
发明人： Dimitrios Konstantinos Kampouris , Patrick Robinson Huddleston , Craig Edward Banks
IPC分类号： G01N33/50
CPC分类号： G01N33/946 , G01N33/523
摘要： The invention provides an assay method for the detection of a primary amine analyte in an aqueous body fluid, which method comprises contacting a sample of said body fluid at a pH below 9.5 with a thiol and an unsaturated cis-dialdehyde and testing for the presence of a pyrrole reaction product.
摘要翻译：本发明提供了用于检测体液中的伯胺分析物的测定方法，该方法包括使pH低于9.5的所述体液样品与硫醇和不饱和顺式二醛接触，并测试是否存在吡咯反应产物。

10. 发明申请

US20100147705A1 Amperometric Sensor and Method for the Detection of Gaseous Analytes Comprising A Working Electrode Comprising Edge Plane Pyrolytic Graphite 审中-公开
标题翻译：用于检测包含边缘热解石墨的工作电极的气体分析物的电流传感器和方法
公开(公告)号：US20100147705A1
公开(公告)日：2010-06-17
申请号：US11722333
申请日：2005-12-22
申请人： Richard Guy Compton , Craig Edward Banks
发明人： Richard Guy Compton , Craig Edward Banks
IPC分类号： G01N27/26
CPC分类号： G01N27/4045 , G01N27/308 , G01N33/0037 , Y02A50/245
摘要： An electrochemical sensor and method of detecting gaseous analytes are provided, which involve the use of a working electrode comprising edge plane pyrolytic graphite.
摘要翻译：提供了一种检测气体分析物的电化学传感器和方法，其涉及使用包括边缘平面热解石墨的工作电极。

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