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1. 发明申请

US20130197336A1 SENSOR OVER-MOLD SHAPE 有权
标题翻译：传感器过模型
公开(公告)号：US20130197336A1
公开(公告)日：2013-08-01
申请号：US13362371
申请日：2012-01-31
申请人： Daniel S. Flo , James K. Carney , Kamal Deep Mothilal , Jon D. Schell
发明人： Daniel S. Flo , James K. Carney , Kamal Deep Mothilal , Jon D. Schell
IPC分类号： A61B5/04
CPC分类号： A61B5/6861 , A61B5/0215 , A61B5/6876 , A61B2560/0406 , A61B2562/0247 , A61B2562/162 , A61B2562/18 , G01L19/146
摘要： An implantable sensor module and medical device includes a housing having an inner shell having a thickness extending between an inner wall and an outer wall and an outer layer, wherein the inner shell and the outer layer form a substantially flat portion. A shoulder extends adjacent to a diaphragm to extend the outer layer laterally away from a central medial line extending between edges of the diaphragm. A recess portion is formed between the diaphragm and an inner side of the outer layer, and an over-fill channel is formed by the outer layer extending through the outer layer from an opening formed at the outer wall to an opening formed along the inner side of the outer layer extending along the substantially flat portion.
摘要翻译：可植入传感器模块和医疗装置包括壳体，该壳体具有在内壁和外壁之间延伸的厚度和外层，其中内壳和外层形成基本平坦的部分。肩部邻近隔膜延伸，以将外层横向远离在隔膜的边缘之间延伸的中央中线延伸。在隔膜和外层的内侧之间形成有凹部，通过从形成在外壁的开口部延伸穿过外层的外层向内侧形成的开口形成有填充通道的外层沿着基本上平坦的部分延伸。

2. 发明授权

US09517032B2 Sensor over-mold shape 有权
标题翻译：传感器过模具形状
公开(公告)号：US09517032B2
公开(公告)日：2016-12-13
申请号：US13362371
申请日：2012-01-31
申请人： Daniel S. Flo , James K. Carney , Kamal Deep Mothilal , Jon D. Schell
发明人： Daniel S. Flo , James K. Carney , Kamal Deep Mothilal , Jon D. Schell
IPC分类号： G01L7/00 , A61B5/00 , A61B5/0215 , G01L19/14
CPC分类号： A61B5/6861 , A61B5/0215 , A61B5/6876 , A61B2560/0406 , A61B2562/0247 , A61B2562/162 , A61B2562/18 , G01L19/146
摘要： An implantable sensor module and medical device includes a housing having an inner shell having a thickness extending between an inner wall and an outer wall and an outer layer, wherein the inner shell and the outer layer form a substantially flat portion. A shoulder extends adjacent to a diaphragm to extend the outer layer laterally away from a central medial line extending between edges of the diaphragm. A recess portion is formed between the diaphragm and an inner side of the outer layer, and an over-fill channel is formed by the outer layer extending through the outer layer from an opening formed at the outer wall to an opening formed along the inner side of the outer layer extending along the substantially flat portion.
摘要翻译：可植入传感器模块和医疗装置包括壳体，该壳体具有在内壁和外壁之间延伸的厚度和外层，其中内壳和外层形成基本平坦的部分。肩部邻近隔膜延伸，以将外层横向远离在隔膜的边缘之间延伸的中心中线延伸。在隔膜和外层的内侧之间形成有凹部，通过从形成在外壁的开口部延伸穿过外层的外层向内侧形成的开口形成有填充通道的外层沿着基本上平坦的部分延伸。

3. 发明授权

US09131858B2 Sensor over-mold shape 有权
标题翻译：传感器过模具形状
公开(公告)号：US09131858B2
公开(公告)日：2015-09-15
申请号：US13362270
申请日：2012-01-31
申请人： Daniel S. Flo , James K. Carney , Kamal Deep Mothilal , Jon D. Schell
发明人： Daniel S. Flo , James K. Carney , Kamal Deep Mothilal , Jon D. Schell
IPC分类号： G01L7/08 , A61B5/02 , A61N1/00 , A61B5/0215 , G01L19/14
CPC分类号： A61B5/0215 , A61B2562/162 , G01L19/149
摘要： An implantable sensor module includes a housing having an inner shell and an outer layer formed to extend over and enclose the inner shell to form an outer wall of the housing, the inner shell having a thickness extending between an inner wall of the inner shell and an outer wall of the inner shell, the outer layer having an inner side engaged against the outer wall of the inner shell and having a thickness extending between the inner side and the outer wall of the housing, wherein the inner shell and the outer layer form a substantially flat portion. A flexible diaphragm is formed within the inner shell and extends between a first edge and a second edge, and a shoulder extends adjacent to the first edge to extend the outer layer laterally away from a central medial line extending between the first and second edges of the diaphragm.
摘要翻译：可植入传感器模块包括壳体，该壳体具有内壳和形成为延伸并包围内壳以形成外壳的外壁的外层，内壳具有在内壳的内壁和所述外层具有与所述内壳的外壁接合并具有在所述壳体的内侧和外壁之间延伸的厚度的内侧，其中所述内壳和所述外层形成基本平坦的部分。柔性隔膜形成在内壳内并且在第一边缘和第二边缘之间延伸，并且肩部相邻于第一边缘延伸，以使外层横向远离在中间内线延伸的第二边缘和第二边缘之间延伸隔膜

4. 发明授权

US09005134B2 Sensor over-mold shape 有权
标题翻译：传感器过模具形状
公开(公告)号：US09005134B2
公开(公告)日：2015-04-14
申请号：US13362305
申请日：2012-01-31
申请人： Daniel S. Flo , James K. Carney , Kamal Deep Mothilal , Jon D. Schell
发明人： Daniel S. Flo , James K. Carney , Kamal Deep Mothilal , Jon D. Schell
IPC分类号： A61B5/00 , A61B5/0215 , A61B5/03 , G01L9/00 , G01L19/00
CPC分类号： A61B5/6843 , A61B5/0215 , A61B5/03 , A61B5/686 , A61B2562/0247 , G01L9/003 , G01L9/0072 , G01L19/0038
摘要： An implantable medical device having a flexible diaphragm is provided with a housing including a shell and an outer layer. The flexible diaphragm extends along the shell. The outer layer has an outer surface and an inner surface. An adhesive coating is applied between the diaphragm and the inner surface of the outer layer. The outer layer includes a recess along the diaphragm for receiving the adhesive.
摘要翻译：具有柔性隔膜的可植入医疗装置设置有包括外壳和外层的外壳。柔性膜片沿壳体延伸。外层具有外表面和内表面。在隔膜和外层的内表面之间施加粘合剂涂层。外层包括沿隔膜的凹部，用于接收粘合剂。

5. 发明申请

US20130197396A1 SENSOR OVER-MOLD SHAPE 有权
标题翻译：传感器过模型
公开(公告)号：US20130197396A1
公开(公告)日：2013-08-01
申请号：US13362305
申请日：2012-01-31
申请人： Daniel S. Flo , James K. Carney , Kamal Deep Mothilal , Jon D. Schell
发明人： Daniel S. Flo , James K. Carney , Kamal Deep Mothilal , Jon D. Schell
IPC分类号： A61B5/103 , A61B5/00
CPC分类号： A61B5/6843 , A61B5/0215 , A61B5/03 , A61B5/686 , A61B2562/0247 , G01L9/003 , G01L9/0072 , G01L19/0038
摘要： An implantable medical device having a flexible diaphragm is provided with a housing including a shell and an outer layer. The flexible diaphragm extends along the shell. The outer layer has an outer surface and an inner surface. An adhesive coating is applied between the diaphragm and the inner surface of the outer layer. The outer layer includes a recess along the diaphragm for receiving the adhesive.
摘要翻译：具有柔性隔膜的可植入医疗装置设置有包括外壳和外层的外壳。柔性膜片沿壳体延伸。外层具有外表面和内表面。在隔膜和外层的内表面之间施加粘合剂涂层。外层包括沿隔膜的凹部，用于接收粘合剂。

6. 发明申请

US20130192377A1 SENSOR OVER-MOLD SHAPE 有权
标题翻译：传感器过模型
公开(公告)号：US20130192377A1
公开(公告)日：2013-08-01
申请号：US13362270
申请日：2012-01-31
申请人： Daniel S. Flo , James K. Carney , Kamal Deep Mothilal , Jon D. Schell
发明人： Daniel S. Flo , James K. Carney , Kamal Deep Mothilal , Jon D. Schell
IPC分类号： G01L7/08
CPC分类号： A61B5/0215 , A61B2562/162 , G01L19/149
摘要： An implantable sensor module includes a housing having an inner shell and an outer layer formed to extend over and enclose the inner shell to form an outer wall of the housing, the inner shell having a thickness extending between an inner wall of the inner shell and an outer wall of the inner shell, the outer layer having an inner side engaged against the outer wall of the inner shell and having a thickness extending between the inner side and the outer wall of the housing, wherein the inner shell and the outer layer form a substantially flat portion. A flexible diaphragm is formed within the inner shell and extends between a first edge and a second edge, and a shoulder extends adjacent to the first edge to extend the outer layer laterally away from a central medial line extending between the first and second edges of the diaphragm.
摘要翻译：可植入传感器模块包括壳体，该壳体具有内壳和形成为延伸并包围内壳以形成外壳的外壁的外层，内壳具有在内壳的内壁和所述外层具有与所述内壳的外壁接合并具有在所述壳体的内侧和外壁之间延伸的厚度的内侧，其中所述内壳和所述外层形成基本平坦的部分。柔性隔膜形成在内壳内并且在第一边缘和第二边缘之间延伸，并且肩部相邻于第一边缘延伸，以使外层横向远离在中间内线延伸的第二边缘和第二边缘之间延伸隔膜

7. 发明授权

US09867990B2 Determination of dipole for tissue conductance communication 有权
公开(公告)号：US09867990B2
公开(公告)日：2018-01-16
申请号：US12915788
申请日：2010-10-29
申请人： Can Cinbis , David A. Anderson , Michael A. Reinert , Xiaonan Shen , James K. Carney , Michael B. Terry
发明人： Can Cinbis , David A. Anderson , Michael A. Reinert , Xiaonan Shen , James K. Carney , Michael B. Terry
IPC分类号： A61N1/40 , A61N1/372 , A61B5/00 , A61N1/08 , H04B13/00
CPC分类号： A61N1/37217 , A61B5/0028 , A61N1/08 , H04B13/005
摘要： Aspects of the present disclosure include a medical device system including an implantable medical device and an external device with three or more electrodes configured to contact a patient's skin. The external device either transmits or receives a test signal to or from the implantable medical device using a plurality of possible receive dipoles, where each possible receive dipole is formed by a pair of electrodes. A signal quality monitor, either at the implantable medical device or at the external device, measures a signal quality for the possible receive dipoles.

8. 发明授权

US09179852B2 Heart monitoring systems, apparatus and methods adapted to detect myocardial ischemia 有权
标题翻译：适用于检测心肌缺血的心脏监测系统，装置和方法
公开(公告)号：US09179852B2
公开(公告)日：2015-11-10
申请号：US11684794
申请日：2007-03-12
申请人： Sarah A. Audet , James K. Carney , William J. Combs
发明人： Sarah A. Audet , James K. Carney , William J. Combs
IPC分类号： A61B5/04 , A61B5/0452 , A61B5/0402 , A61B5/00
CPC分类号： A61B5/0452 , A61B5/0006 , A61B5/0031 , A61B5/0402 , A61B5/721 , A61B5/7475
摘要： Embodiments include heart monitoring systems, apparatus, and methods adapted to detect myocardial ischemia. An apparatus includes at least one first-tier sensor/analyzer adapted to sense a first input related to cardiac function, and to produce a first-tier trigger signal when the first input indicates myocardial ischemia. In an embodiment, a first-tier sensor/analyzer includes an ECG sensor/analyzer. In another embodiment, a first-tier sensor/analyzer includes a patient activator. An apparatus further includes at least one second-tier sensor/analyzer adapted to sense a second input related to cardiac function, and to produce a second-tier trigger signal when the second input indicates myocardial ischemia. In an embodiment, a second-tier sensor-analyzer includes a heart sound sensor/analyzer. A triggering element is adapted to produce a response-invoking signal in response to the first-tier trigger signal and the second-tier trigger signal. The response-invoking signal may invoke a patient alert, a message to an external system, and/or a cardiac stimulus.
摘要翻译：实施例包括适于检测心肌缺血的心脏监测系统，装置和方法。一种装置包括适于感测与心脏功能相关的第一输入的至少一个第一层传感器/分析器，以及当第一输入指示心肌缺血时产生第一层触发信号。在一个实施例中，第一层传感器/分析器包括ECG传感器/分析器。在另一个实施例中，第一层传感器/分析器包括患者激活器。装置还包括适于感测与心脏功能相关的第二输入的至少一个第二层传感器/分析器，并且当第二输入指示心肌缺血时产生第二层触发信号。在一个实施例中，第二层传感器分析仪包括心音传感器/分析器。触发元件适于响应于第一层触发信号和第二层触发信号产生响应调用信号。响应调用信号可以调用患者警报，到外部系统的消息和/或心脏刺激。

9. 发明授权

US09126049B2 Shock reduction using absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction 有权
$Shock reduction using absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction$
标题翻译：使用绝对校准的组织氧饱和度和总血红蛋白体积分数进行减震
公开(公告)号：US09126049B2
公开(公告)日：2015-09-08
申请号：US12797781
申请日：2010-06-10
申请人： Jonathan L. Kuhn , Can Cinbis , David A. Anderson , James K. Carney
发明人： Jonathan L. Kuhn , Can Cinbis , David A. Anderson , James K. Carney
IPC分类号： A61B5/00 , A61N1/362 , A61B5/02 , A61B5/145 , A61B5/1459 , A61N1/365 , A61N1/39 , A61B5/0215 , A61B5/042 , A61B5/11
CPC分类号： A61N1/3622 , A61B5/02028 , A61B5/0215 , A61B5/042 , A61B5/1116 , A61B5/14542 , A61B5/1459 , A61N1/36557 , A61N1/3956
摘要： An implantable medical device for detecting and treating an arrhythmia includes an optical sensor adapted for positioning adjacent to a blood-perfused tissue volume. In one embodiment for controlling arrhythmia therapies delivered by the device, the optical sensor is controlled to emit light in response to detecting an arrhythmia, detect light scattered by the volume of blood perfused tissue including measuring an optical sensor output signal corresponding to the intensity of scattered light for at least four spaced-apart wavelengths, and compute a volume-independent measure of tissue oxygen saturation from the detected light. The hemodynamic status of the arrhythmia is detected in response to the measure of tissue oxygen saturation.
摘要翻译：用于检测和治疗心律失常的可植入医疗装置包括适于邻近于血液灌注的组织体积定位的光学传感器。在用于控制由装置传送的心律失常治疗的一个实施例中，响应于检测到心律失常，控制光学传感器发光，检测由血液灌注组织的体积散射的光，包括测量对应于散射强度的光学传感器输出信号用于至少四个间隔波长的光，并且从检测到的光计算组织氧饱和度的体积独立测量。响应于组织氧饱和度的测量，检测心律失常的血液动力学状态。

10. 发明授权

US08170650B2 Implantable tissue perfusion sensing system and method 有权
标题翻译：植入式组织灌注感应系统及方法
公开(公告)号：US08170650B2
公开(公告)日：2012-05-01
申请号：US12039242
申请日：2008-02-28
申请人： Can Cinbis , James K. Carney , William T. Donofrio , Robert M. Ecker
发明人： Can Cinbis , James K. Carney , William T. Donofrio , Robert M. Ecker
IPC分类号： A61B6/00
CPC分类号： A61B5/1459 , A61B5/0059 , A61B5/024 , A61B5/046 , A61B5/0464 , A61B5/14542 , A61B5/7214 , A61N1/3925
摘要： A medical device for sensing cardiac events that includes a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect the emitted light. A processor generates an ambient light measurement in response to ambient light detected by the detector, generates a plurality of light measurements in response to the emitted light detected by the detector, and adjusts the plurality of light measurements in response to the ambient light measurement.
摘要翻译：一种用于感测心脏事件的医疗装置，其包括能够发射多个波长的光的多个光源，以及检测器，用于检测发射的光。处理器响应于由检测器检测到的环境光产生环境光测量，响应于由检测器检测到的发射光产生多个光测量，并且响应于环境光测量来调整多个光测量。

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