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1. 发明申请

US20050135702A1 Methods, systems and computer software for detecting pixel stutter 审中-公开
公开(公告)号：US20050135702A1
公开(公告)日：2005-06-23
申请号：US11021199
申请日：2004-12-21
申请人： Daniel Bartell , Richard Watts
发明人： Daniel Bartell , Richard Watts
IPC分类号： H04N1/00 , G06K9/36 , G06K9/00 , G06K9/46
CPC分类号： H04N1/00005 , H04N1/00002 , H04N1/00018 , H04N1/00034 , H04N1/00068 , H04N1/00074 , H04N1/00408
摘要： Embodiments of the invention provide methods, computer software products and systems for detecting pixel stutter of a scanner. In one embodiment, a numeric count of stuttered pixels in both the x (row) and y (column) directions and a graphic display of the stuttered pixels overlaid on the image data are provided by the invention. The y-direction stutter count provides the estimate of pixel stutter from pure statistical data variations.

2. 发明申请

US20060052308A1 Transglutaminase inhibitors and methods of use thereof 失效
公开(公告)号：US20060052308A1
公开(公告)日：2006-03-09
申请号：US11213173
申请日：2005-08-26
申请人： Chaitan Khosla , Richard Watts , Matthew Siegel , Daniel Pinkas , Kihang Choi , Keith Rich
发明人： Chaitan Khosla , Richard Watts , Matthew Siegel , Daniel Pinkas , Kihang Choi , Keith Rich
IPC分类号： A61K38/08 , A61K38/06 , A61K31/42
CPC分类号： A61K31/4709 , A61K31/42 , A61K31/421 , A61K38/005 , A61K45/06 , C07D261/04 , C07D413/12 , C07D413/14 , C07K7/06 , A61K2300/00
摘要： Transglutaminase inhibitors and methods of use thereof are provided.

3. 发明授权

US07545967B1 System and method for generating composite subtraction images for magnetic resonance imaging 有权
标题翻译：用于生成用于磁共振成像的复合减影图像的系统和方法
公开(公告)号：US07545967B1
公开(公告)日：2009-06-09
申请号：US10664425
申请日：2003-09-17
申请人： Martin R. Prince , Ramin Zabih , Yi Wang , Richard Watts , Junhwan Kim , Jeff Bezanson , Hale Ersoy
发明人： Martin R. Prince , Ramin Zabih , Yi Wang , Richard Watts , Junhwan Kim , Jeff Bezanson , Hale Ersoy
IPC分类号： G06K9/00
CPC分类号： G06T5/50 , G06K2209/05 , G06T2207/10076 , G06T2207/10088 , G06T2207/30101 , Y10S128/92 , Y10S128/922
摘要： In time-resolved contrast-enhanced magnetic resonance angiography, a measure quantifying image quality provides a basis for generating a linear filtered composite image by facilitating selection of a mask and an arterial phase image for subtraction. Filtering of individual pixels of a temporal series of images provides enhanced contrast in a single image by allowing the temporal behavior of the pixel intensity to denote representation as an artery, vein or background tissue. Motion artifacts are suppressed by re-registering sequential images, adjusting weighting before averaging and subtraction and filtering the Fourier data to eliminate data corrupted by motion or other phenomena.
摘要翻译：在时间分辨的对比度增强磁共振血管造影术中，量化图像质量的度量为通过促进选择掩模和用于减法的动脉相位图像生成线性滤波的复合图像提供了基础。通过使像素强度的时间行为表示为动脉，静脉或背景组织，对时间序列图像中的各个像素进行滤波，从而在单个图像中提供增强的对比度。通过重新注册顺序图像来抑制运动伪影，在平均和减法之前调整加权并对傅立叶数据进行滤波以消除由运动或其他现象损坏的数据。

4. 发明授权

US07114212B1 Boot cleaning device 失效
标题翻译：启动清洁装置
公开(公告)号：US07114212B1
公开(公告)日：2006-10-03
申请号：US10351653
申请日：2003-01-28
申请人： Richard Watts
发明人： Richard Watts
IPC分类号： A47L23/02 , A47L23/22 , A46B11/06 , A46B13/02
CPC分类号： A47L23/263 , A46B13/001 , A46B13/06 , A46B2200/306 , A47L23/02
摘要： A boot cleaning device includes a base having a bottom surface and a top surface. The top surface has an opening extending therein. A water inlet extends though an outer wall of the base and into a cavity positioned in the based. The water inlet has a coupler extending outwardly from the base. A supply tube has a first end and a second end. The first end is fluidly coupled to the water inlet. The second end extends upwardly through the opening. A water outlet extends into the outer wall of the base and into the cavity. A cleaning assembly is rotatably mounted in the opening. The supply tube extends upwardly through the cleaning assembly.
摘要翻译：靴子清洁装置包括具有底表面和顶表面的底座。顶面具有在其中延伸的开口。进水口通过基座的外壁延伸到位于基座中的空腔中。进水口具有从基座向外延伸的耦合器。供应管具有第一端和第二端。第一端流体地联接到进水口。第二端向上延伸穿过开口。出水口延伸到基座的外壁并进入空腔。清洁组件可旋转地安装在开口中。供应管向上延伸穿过清洁组件。

5. 发明授权

US07003343B2 Method and apparatus for anatomically tailored k-space sampling and recessed elliptical view ordering for bolus-enhanced 3D MR angiography 有权
公开(公告)号：US07003343B2
公开(公告)日：2006-02-21
申请号：US10109888
申请日：2002-04-01
申请人： Richard Watts , Yi Wang , Martin R. Prince
发明人： Richard Watts , Yi Wang , Martin R. Prince
IPC分类号： A61B5/05 , G01V3/00
CPC分类号： G01R33/5601 , A61B5/055
摘要： Current bolus chase magnetic resonance angiography is limited by the imaging time for each station. Tailoring the density of k-space sampling along the anterior-posterior direction of the coronal station allows a substantial decrease in scan time that leads to greater contrast bolus sharing among stations and consequently a significant improvement in image quality. Fast arterial-venous transit in the carotid arteries requires accurate, reliable timing of the acquisition to the bolus transit to maximize arterial signal and minimize venous artifacts. The rising edge of the bolus is not utilized in conventional elliptical-centric view ordering because the critical k-space center must be acquired with full arterial enhancement. The invention provides a recessed elliptical-centric view ordering scheme is introduced in which the k-space center is acquired a few seconds following scan initiation. The recessed view ordering is shown to be more robust to timing errors in a patient studies.

6. 发明申请

US20050203377A1 Method and apparatus for anatomically tailored k-space sampling and recessed elliptical view ordering for bolus-enhanced 3D MR angiography 审中-公开
标题翻译：用于解剖学定制的k空间取样和凹凸椭圆视图排序的方法和装置，用于推注增强的3D MR血管造影
公开(公告)号：US20050203377A1
公开(公告)日：2005-09-15
申请号：US11108417
申请日：2005-04-18
申请人： Richard Watts , Yi Wang , Martin Prince
发明人： Richard Watts , Yi Wang , Martin Prince
IPC分类号： A61B5/055 , G01R33/28 , A61B5/05
CPC分类号： G01R33/5601 , A61B5/055
摘要： Current bolus chase magnetic resonance angiography is limited by the imaging time for each station. Tailoring the density of k-space sampling along the anterior-posterior direction of the coronal station allows a substantial decrease in scan time that leads to greater contrast bolus sharing among stations and consequently a significant improvement in image quality. Fast arterial-venous transit in the carotid arteries requires accurate, reliable timing of the acquisition to the bolus transit to maximize arterial signal and minimize venous artifacts. The rising edge of the bolus is not utilized in conventional elliptical-centric view ordering because the critical k-space center must be acquired with full arterial enhancement. The invention provides a recessed elliptical-centric view ordering scheme is introduced in which the k-space center is acquired a few seconds following scan initiation. The recessed view ordering is shown to be more robust to timing errors in a patient studies.
摘要翻译：目前的推注磁共振血管造影受每个站的成像时间的限制。沿着冠状站的前后方向调整k空间采样的密度允许扫描时间的显着减少，导致站之间更大的对比度推注共享，并且因此显着改善图像质量。在颈动脉中的快速动脉 - 静脉转运需要准确，可靠的采集到推注转运的时间，以最大化动脉信号并使静脉伪影最小化。在常规的以椭圆为中心的视图排序中，推注的上升边缘不被利用，因为必须以完全动脉增强获得临界k空间中心。本发明提供了一种以椭圆为中心的视图排序方案，其中在扫描开始后几秒钟内获取k空间中心。凹陷视图排序显示出对患者研究中的定时误差更为鲁棒。

7. 发明授权

US07734078B2 System and method for generating composite substraction images for magnetic resonance imaging 有权
标题翻译：用于生成用于磁共振成像的复合减影图像的系统和方法
公开(公告)号：US07734078B2
公开(公告)日：2010-06-08
申请号：US12475797
申请日：2009-06-01
申请人： Martin R. Prince , Ramin Zabih , Yi Wang , Richard Watts , Junhwan Kim , Jeff Bezanson , Hale Ersoy
发明人： Martin R. Prince , Ramin Zabih , Yi Wang , Richard Watts , Junhwan Kim , Jeff Bezanson , Hale Ersoy
IPC分类号： G06K9/00
CPC分类号： G06T5/50 , G06K2209/05 , G06T2207/10076 , G06T2207/10088 , G06T2207/30101 , Y10S128/92 , Y10S128/922
摘要： In time-resolved contrast-enhanced magnetic resonance angiography, a measure quantifying image quality provides a basis for generating a linear filtered composite image by facilitating selection of a mask and an arterial phase image for subtraction. Filtering of individual pixels of a temporal series of images provides enhanced contrast in a single image by allowing the temporal behavior of the pixel intensity to denote representation as an artery, vein or background tissue. Motion artifacts are suppressed by re-registering sequential images, adjusting weighting before averaging and subtraction and filtering the Fourier data to eliminate data corrupted by motion or other phenomena.
摘要翻译：在时间分辨的对比度增强磁共振血管造影术中，量化图像质量的度量为通过促进选择掩模和用于减法的动脉相位图像生成线性滤波的复合图像提供了基础。通过使像素强度的时间行为表示为动脉，静脉或背景组织，对时间序列图像中的各个像素进行滤波，从而在单个图像中提供增强的对比度。通过重新注册顺序图像来抑制运动伪影，在平均和减法之前调整加权并对傅立叶数据进行滤波以消除由运动或其他现象损坏的数据。

8. 发明申请

US20090245606A1 SYSTEM AND METHOD FOR GENERATING COMPOSITE SUBSTRACTION IMAGES FOR MAGNETIC RESONANCE IMAGING 有权
标题翻译：用于生成用于磁共振成像的复合成像图像的系统和方法
公开(公告)号：US20090245606A1
公开(公告)日：2009-10-01
申请号：US12475797
申请日：2009-06-01
申请人： Martin R. Prince , Ramin Zabih , Yi Wang , Richard Watts , Junhwan Kim , Jeff Bezanson , Hale Ersoy
发明人： Martin R. Prince , Ramin Zabih , Yi Wang , Richard Watts , Junhwan Kim , Jeff Bezanson , Hale Ersoy
IPC分类号： G06K9/00
CPC分类号： G06T5/50 , G06K2209/05 , G06T2207/10076 , G06T2207/10088 , G06T2207/30101 , Y10S128/92 , Y10S128/922
摘要： In time-resolved contrast-enhanced magnetic resonance angiography, a measure quantifying image quality provides a basis for generating a linear filtered composite image by facilitating selection of a mask and an arterial phase image for subtraction. Filtering of individual pixels of a temporal series of images provides enhanced contrast in a single image by allowing the temporal behavior of the pixel intensity to denote representation as an artery, vein or background tissue. Motion artifacts are suppressed by re-registering sequential images, adjusting weighting before averaging and subtraction and filtering the Fourier data to eliminate data corrupted by motion or other phenomena.
摘要翻译：在时间分辨的对比度增强磁共振血管造影术中，量化图像质量的度量为通过促进选择掩模和用于减法的动脉相位图像生成线性滤波的复合图像提供了基础。通过使像素强度的时间行为表示为动脉，静脉或背景组织，对时间序列图像中的各个像素进行滤波，从而在单个图像中提供增强的对比度。通过重新注册顺序图像来抑制运动伪影，在平均和减法之前调整加权并对傅立叶数据进行滤波以消除由运动或其他现象损坏的数据。

9. 发明授权

US06907146B2 Methods, systems and computer software for detecting pixel stutter 有权
标题翻译：方法，系统和计算机软件，用于检测像素点
公开(公告)号：US06907146B2
公开(公告)日：2005-06-14
申请号：US09734751
申请日：2000-12-11
申请人： Daniel M. Bartell , Richard Watts
发明人： Daniel M. Bartell , Richard Watts
IPC分类号： H04N1/00 , G06K7/00
CPC分类号： H04N1/00005 , H04N1/00002 , H04N1/00018 , H04N1/00034 , H04N1/00068 , H04N1/00074 , H04N1/00408
摘要： Embodiments of the invention provide methods, computer software products and systems for detecting pixel stutter of a scanner. In one embodiment, a numeric count of stuttered pixels in both the x (row) and y (column) directions and a graphic display of the stuttered pixels overlaid on the image data are provided by the invention. The y-direction stutter count provides the estimate of pixel stutter from pure statistical data variations.
摘要翻译：本发明的实施例提供了用于检测扫描仪的像素状态的方法，计算机软件产品和系统。在一个实施例中，本发明提供了x（行）和y（列）方向上的破坏像素的数字计数和覆盖在图像数据上的混乱像素的图形显示。 y方向的统计数据提供了纯统计数据变化的像素点数的估计。

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