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    • 9. 发明申请
    • TRANSDERMAL ABSORPTION PREPARATION
    • 超吸收制剂
    • US20130165875A1
    • 2013-06-27
    • US13642960
    • 2011-04-21
    • Young Kweon ChoiJung Ju KimSeong Su KimJung Sik LeeSeong Min Park
    • Young Kweon ChoiJung Ju KimSeong Su KimJung Sik LeeSeong Min Park
    • A61M35/00
    • A61K9/7061A61K9/7053A61K9/7076A61K31/4045
    • The present, invention relates to a transdermal absorption preparation. The transdermal absorption preparation of the present invention comprises a drug-containing adhesive layer, a drug-protective layer and a release layer, wherein the drug-containing adhesive layer contains ropinirole or a salt thereof, rubber, an adhesion-imparting resin, an antioxidant, and a transdermal absorption promoter. Also, the present invention provides a transdermal absorption preparation comprising a drug-containing adhesive layer, a drug-protective layer, and a release layer, wherein the drug-containing adhesive layer contains ropinirole or a salt thereof, acrylic rubber, an anti-crystallisation agent, and a transdermal absorption promoter. When the transdermal absorption preparation of the present invention is used for the treatment of Parkinson's disease or restless leg syndrome, no side effect due to an increase in the initial drug concentration in blood occurs and the skin penetration effect of the drug is excellent.
    • 本发明涉及一种透皮吸收制剂。 本发明的透皮吸收制剂包含含药物的粘合剂层,药物保护层和剥离层,其中含药物的粘合剂层含有罗哌尼罗或其盐,橡胶,赋形树脂,抗氧化剂 ,和透皮吸收促进剂。 另外,本发明提供了含有药物的粘合剂层,药物保护层和剥离层的透皮吸收制剂,其中含药物的粘合剂层含有罗哌尼罗或其盐,丙烯酸橡胶,抗结晶 试剂和透皮吸收促进剂。 当本发明的经皮吸收制剂用于治疗帕金森病或不宁腿综合征时,由于血液中初始药物浓度的增加而引起副作用,药物的皮肤渗透作用优异。