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1. 发明授权

US10947555B2 Herbicide resistance genes 有权
公开(公告)号：US10947555B2
公开(公告)日：2021-03-16
申请号：US15288406
申请日：2016-10-07
申请人： Dow AgroSciences LLC
发明人： Terry Wright , Justin Lira , Donald Merlo , Nicole Arnold
IPC分类号： C12N15/82 , C12N9/02
摘要： The subject invention provides novel plants that are not only resistant to 2,4-D and other phenoxy auxin herbicides, but also to aryloxyphenoxypropionate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention alone or “stacked” together with another herbicide resistance gene, preferably a glyphosate resistance gene, so as to provide broader and more robust weed control, increased treatment flexibility, and improved herbicide resistance management options. More specifically, preferred enzymes and genes for use according to the subject invention are referred to herein as AAD (aryloxyalkanoate dioxygenase) genes and proteins. No α-ketoglutarate-dependent dioxygenase enzyme has previously been reported to have the ability to degrade herbicides of different chemical classes and modes of action. This highly novel discovery is the basis of significant herbicide tolerant crop trait opportunities as well as development of selectable marker technology. The subject invention also includes related methods of controlling weeds. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the formation of, and controlling, weeds that are resistant (or naturally more tolerant) to one or more herbicides such as glyphosate.

2. 发明授权

US11299745B1 Herbicide resistance genes 有权
公开(公告)号：US11299745B1
公开(公告)日：2022-04-12
申请号：US17403476
申请日：2021-08-16
申请人： DOW AGROSCIENCES LLC
发明人： Terry Wright , Justin Lira , Donald Merlo , Nicole Arnold
IPC分类号： C12N15/82 , C12N9/02
摘要： The subject invention provides novel plants that are not only resistant to 2,4-D and other phenoxy auxin herbicides, but also to aryloxyphenoxypropionate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention alone or “stacked” together with another herbicide resistance gene, preferably a glyphosate resistance gene, so as to provide broader and more robust weed control, increased treatment flexibility, and improved herbicide resistance management options. More specifically, preferred enzymes and genes for use according to the subject invention are referred to herein as AAD (aryloxyalkanoate dioxygenase) genes and proteins. No α-ketoglutarate-dependent dioxygenase enzyme has previously been reported to have the ability to degrade herbicides of different chemical classes and modes of action. This highly novel discovery is the basis of significant herbicide tolerant crop trait opportunities as well as development of selectable marker technology. The subject invention also includes related methods of controlling weeds. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the formation of, and controlling, weeds that are resistant (or naturally more tolerant) to one or more herbicides such as glyphosate.

3. 发明授权

US10174337B2 Herbicide resistance genes 有权
公开(公告)号：US10174337B2
公开(公告)日：2019-01-08
申请号：US14820893
申请日：2015-08-07
申请人： Dow AgroSciences LLC
发明人： Terry Wright , Justin Lira , Donald Merlo , Nicole Arnold
IPC分类号： C12N15/82 , C12N9/02
摘要： The subject invention provides novel plants that are not only resistant to 2,4-D and other phenoxy auxin herbicides, but also to aryloxyphenoxypropionate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention alone or “stacked” together with another herbicide resistance gene, preferably a glyphosate resistance gene, so as to provide broader and more robust weed control, increased treatment flexibility, and improved herbicide resistance management options. More specifically, preferred enzymes and genes for use according to the subject invention are referred to herein as AAD (aryloxyalkanoate dioxygenase) genes and proteins. No α-ketoglutarate-dependent dioxygenase enzyme has previously been reported to have the ability to degrade herbicides of different chemical classes and modes of action. This highly novel discovery is the basis of significant herbicide tolerant crop trait opportunities as well as development of selectable marker technology. The subject invention also includes related methods of controlling weeds. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the formation of, and controlling, weeds that are resistant (or naturally more tolerant) to one or more herbicides such as glyphosate.

4. 发明授权

US11149283B2 Herbicide resistance genes 有权
公开(公告)号：US11149283B2
公开(公告)日：2021-10-19
申请号：US17175966
申请日：2021-02-15
申请人： DOW AGROSCIENCES LLC
发明人： Terry Wright , Justin Lira , Donald Merlo , Nicole Arnold
IPC分类号： C12N15/82 , C12N9/02
摘要： The subject invention provides novel plants that are not only resistant to 2,4-D and other phenoxy auxin herbicides, but also to aryloxyphenoxypropionate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention alone or “stacked” together with another herbicide resistance gene, preferably a glyphosate resistance gene, so as to provide broader and more robust weed control, increased treatment flexibility, and improved herbicide resistance management options. More specifically, preferred enzymes and genes for use according to the subject invention are referred to herein as AAD (aryloxyalkanoate dioxygenase) genes and proteins. No α-ketoglutarate-dependent dioxygenase enzyme has previously been reported to have the ability to degrade herbicides of different chemical classes and modes of action. This highly novel discovery is the basis of significant herbicide tolerant crop trait opportunities as well as development of selectable marker technology. The subject invention also includes related methods of controlling weeds. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the formation of, and controlling, weeds that are resistant (or naturally more tolerant) to one or more herbicides such as glyphosate.

5. 发明授权

US10323287B2 AAD-1 event DAS-40278-9, related transgenic corn lines, and event-specific identification thereof 有权
公开(公告)号：US10323287B2
公开(公告)日：2019-06-18
申请号：US14989787
申请日：2016-01-06
申请人： DOW AGROSCIENCES LLC
发明人： Yunxing Cory Cui , Jill Bryan , Donald Maum , Greg Gilles , Terry Wright , Jennifer Hamilton , Nicole Arnold , Nathan VanOpdorp , Tina Kaiser , Ning Zhou
IPC分类号： C12Q1/68 , C12N15/82 , C12Q1/6895 , A01H5/10 , C12N9/02
摘要： This invention relates in part to plant breeding and herbicide tolerant plants. This invention includes a novel aad-1 transformation event in corn plants comprising a polynucleotide sequence, as described herein, inserted into a specific site within the genome of a corn cell. In some embodiments, said event/polynucleotide sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. Additionally, the subject invention provides assays for detecting the presence of the subject event in a sample (of corn grain, for example). The assays can be based on the DNA sequence of the recombinant construct, inserted into the corn genome, and on the genomic sequences flanking the insertion site. Kits and conditions useful in conducting the assays are also provided.

6. 发明授权

US11098322B2 AAD-1 event DAS-40278-9, related transgenic corn lines, and event-specific identification thereof 有权
公开(公告)号：US11098322B2
公开(公告)日：2021-08-24
申请号：US16279055
申请日：2019-02-19
申请人： DOW AGROSCIENCES LLC
发明人： Yunxing Cory Cui , Jill Bryan , Donald Maum , Greg Gilles , Terry Wright , Jennifer Hamilton , Nicole Arnold , Nathan VanOpdorp , Tina Kaiser , Ning Zhou
IPC分类号： C12N15/82 , C12Q1/6895 , C12N9/02
摘要： This invention relates in part to plant breeding and herbicide tolerant plants. This invention includes a novel aad-1 transformation event in corn plants comprising a polynucleotide sequence, as described herein, inserted into a specific site within the genome of a corn cell. In some embodiments, said event/polynucleotide sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. Additionally, the subject invention provides assays for detecting the presence of the subject event in a sample (or corn grain, for example). The assays can be based on the DNA sequence of the recombinant construct, inserted into the corn genome, and on the genomic sequences flanking the insertion site. Kits and conditions useful in conducting the assays are also provided.

7. 发明授权

US10450549B2 Aryloxyphenoxypropionate tolerance in turfrgass species and use of AAD1 as a selectable marker 有权
公开(公告)号：US10450549B2
公开(公告)日：2019-10-22
申请号：US15287630
申请日：2016-10-06
申请人： Dow AgroSciences, LLC
发明人： Carla N. Yerkes , Barbara A. Zilinskas , Donald J. Merlo , Terry R. Wright , Justin Lira , Nicole Arnold , Gary D. Thompson , Ning Zhou , Andrew Worden
IPC分类号： C12N15/82 , C12N9/02
摘要： The present disclosure relates to the use of a grass-active herbicide postemergently applied to AAD1-transformed turfgrasses to selectively control grass weeds in a turf grass crop. Also described is the use of AAD1 as a selectable marker in the production of transgenic turfgrass.

8. 发明申请

US20170088855A1 ARYLOXYPHENOXYPROPIONATE TOLERANCE IN TURFRGASS SPECIES AND USE OF AAD1 AS A SELECTABLE MARKER 审中-公开
公开(公告)号：US20170088855A1
公开(公告)日：2017-03-30
申请号：US15287630
申请日：2016-10-06
申请人： Dow AgroSciences, LLC
发明人： Carla N. Yerkes , Barbara A. Zilinskas , Donald J. Merlo , Terry R. Wright , Justin Lira , Nicole Arnold , Gary D. Thompson , Ning Zhou , Andrew Worden
IPC分类号： C12N15/82 , A01N43/60 , A01N43/40 , A01N39/04
CPC分类号： C12N15/8274 , C12N9/0069 , C12N9/0071 , C12N15/8209
摘要： The present disclosure relates to the use of a grass-active herbicide postemergently applied to AAD1-transformed turfgrasses to selectively control grass weeds in a turf grass crop. Also described is the use of AAD1 as a selectable marker in the production of transgenic turfgrass.

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