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1. 发明申请

US20160047701A1 HOLLOW MICRO STRING BASED CALORIMETER DEVICE 审中-公开
标题翻译：基于微型基于MICRAR的CALORIMETER设备
公开(公告)号：US20160047701A1
公开(公告)日：2016-02-18
申请号：US14782572
申请日：2014-04-04
申请人： Danmarks Tekniske Universitet
发明人： Muhammad Faheem Khan , Silvan Schmid , Anja Boisen , Tom Larsen
IPC分类号： G01K17/00 , G01K7/32
CPC分类号： G01K17/006 , G01K7/32
摘要： The present invention relates to a micron-scale calorimeter and a calorimetry method utilizing the micron-scale calorimeter. In accordance with the invention, there is provided a micron-scale calorimeter comprising a micro-channel string, being restrained at at least two longitudinally distanced positions so as to form a free released double clamped string in-between said two longitudinally distanced positions said micro-channel string comprising a microfluidic channel having a closed cross section and extending in the longitudinal direction of the hollow string, acoustical means adapted to oscillate the string at different frequencies by emitting sound waves towards the string, optical means adapted to detect oscillating frequencies of the string, and controlling means controlling the strength and frequency of the sound wave emitted by the acoustical means and receiving a signal from the optical means representing the detected oscillating frequencies.
摘要翻译：本发明涉及微米级量热计和利用微米级量热计的量热法。根据本发明，提供了一种微米级量热计，其包括微通道串，其被限制在至少两个纵向间隔位置，以便在所述两个纵向间隔位置之间形成自由释放的双夹紧柱，所述微型 - 通道串，其包括具有闭合截面且沿所述中空弦的纵向方向延伸的微流体通道，适于通过向所述弦发射声波而以不同频率振荡所述弦的声学装置，适于检测所述弦的振动频率的光学装置弦和控制装置，用于控制由声学装置发射的声波的强度和频率，并从表示检测到的振荡频率的光学装置接收信号。

2. 发明申请

US20160138908A1 MICROMECHANICAL PHOTOTHERMAL ANALYSER OF MICROFLUIDIC SAMPLES 审中-公开
标题翻译：微生物样品的微生物光热分析仪
公开(公告)号：US20160138908A1
公开(公告)日：2016-05-19
申请号：US14899457
申请日：2014-06-26
申请人： DANMARKS TEKNISKE UNIVERSITET
发明人： Muhammad Faheem Khan , Silvan Schmid , Anja Boisen , Seonghwan Kim , Thomas Thundat
IPC分类号： G01B11/16 , G01N21/31
CPC分类号： G01B11/16 , B01L3/5027 , B01L3/502715 , B01L2300/0636 , B01L2300/0663 , B01L2300/0877 , B01L2300/1838 , G01N21/0303 , G01N21/171 , G01N21/31 , G01N2021/036 , G01N2021/0389 , G01N2201/06113
摘要： The present invention relates to a micromechanical photothermal analyser of microfluidic samples comprising an oblong micro-channel extending longitudinally from a support element, the micro-channel is made from at least two materials with different thermal expansion coefficients, wherein the materials are arranged relatively to each other so that heating of the micro-channel results in a bending of the micro-channel, the first material has a first thermal expansion coefficient and is made from an light-specific transparent penetrable material so that when exposed to ultraviolet, visible, or infrared light, the specific light radiates into the channel through said light transparent material, the second material has a second thermal expansion coefficient being different from the first thermal expansion coefficient. The micromechanical photothermal analyser also comprises an irradiation source being adapted to controlled radiate ultraviolet, visible, or infrared light towards and through the transparent micro-channel, and a deflection detector being adapted to detect the amount of deflection of the micro-channel. The wavelength-deflection plot provides a spectrum of an analyte inside the oblong microchannel. To characterize the analyte the plot is compared with the standard database of spectroscopy.
摘要翻译：本发明涉及微流体样品的微机械光热分析仪，其包括从支撑元件纵向延伸的长圆形微通道，微通道由具有不同热膨胀系数的至少两种材料制成，其中材料相对于每个另一个使得微通道的加热导致微通道的弯曲，第一材料具有第一热膨胀系数，并且由光特异性透明可穿透材料制成，使得当暴露于紫外线，可见光或红外线光，特定的光通过所述透光材料辐射到通道中，第二材料具有与第一热膨胀系数不同的第二热膨胀系数。微机械光热分析仪还包括辐射源，其适于控制朝向和穿过透明微通道的辐射紫外线，可见光或红外光，以及偏转检测器，其适于检测微通道的偏转量。波长偏转图提供长方形微通道内的分析物的光谱。为了表征分析物，将该图与光谱学的标准数据库进行比较。

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