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    • 7. 发明授权
    • Tissue site markers for in vivo imaging
    • 用于体内成像的组织位点标记
    • US08224424B2
    • 2012-07-17
    • US12460052
    • 2009-07-13
    • Fred H. BurbankPaul LubockMichael L. JonesRichard L. QuickFrank LouwStephen A. De Santis
    • Fred H. BurbankPaul LubockMichael L. JonesRichard L. QuickFrank LouwStephen A. De Santis
    • A61B5/00A61B6/00A61B19/00
    • A61M37/0069A61B6/12A61B8/0833A61B10/02A61B90/39A61B2017/00004A61B2090/08021A61B2090/3908A61B2090/3925A61B2090/3987A61K49/006A61K49/222
    • The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.
    • 本发明涉及活检部位标记和标记活组织检查部位的方法,使得活检腔的位置通过常规成像方法,特别是通过超声成像容易看到。 本发明的活检部位标记物具有高的超声反射率,从小标记物呈现出实质的声学特征,以避免在随后的成像研究中掩盖诊断组织特征,并且可以容易地与生物特征区别开来。 本发明的活检部位标记物的几个公开的实施方案具有放置在组织部位中的声阻抗的高对比度,以便有效地反射和散射超声能量,并且优选地包括气体填充的内部孔。 标记可以具有不均匀的表面轮廓以增强声学特征。 标记具有在医学成像期间可识别人造的特征形式。 可以将活检部位标记物精确地固定到活检部位,以便当放置放置器械被取出时以及随后标记的组织被移动或操纵时抵抗从活检腔的迁移。
    • 9. 发明授权
    • Adjustable implant and method of use
    • 可植入植入物和使用方法
    • US07981025B2
    • 2011-07-19
    • US12259965
    • 2008-10-28
    • Scott PoolBlair WalkerJay R. McCoyPeter P. TranRichard L. QuickShahram MoaddebArvin Chang
    • Scott PoolBlair WalkerJay R. McCoyPeter P. TranRichard L. QuickShahram MoaddebArvin Chang
    • A61F2/00
    • A61F5/0053A61F5/003A61F5/0059A61F5/0066A61F2005/002
    • A system includes an adjustable implant configured for implantation internally within a subject, the adjustable implant having a permanent magnet configured for rotation about an axis of rotation, the permanent magnet operatively coupled to a drive transmission configured to alter a dimension of the adjustable implant. The system further includes an external adjustment device configured for placement on or adjacent to the skin of the subject comprising at least one magnet configured for rotation, the external adjustment device further comprising a motor configured to rotate the at least one magnet, whereby rotation of the at least one magnet of the external adjustment device effectuates rotational movement of the permanent magnet of the adjustable implant and alters the dimension of the adjustable implant. The system includes drive control circuitry configured to drive the motor of the external adjustment device to achieve a target dimension of the adjustable implant.
    • 系统包括被配置用于在对象内部进行植入的可调节植入物,所述可调节植入物具有被配置为围绕旋转轴线旋转的永磁体,所述永磁体可操作地耦合到构造成改变可调节植入物的尺寸的驱动变速器。 所述系统还包括外部调节装置,其被配置为放置在所述对象的皮肤上或与所述对象的皮肤相邻,所述外部调节装置包括被配置为旋转的至少一个磁体,所述外部调整装置还包括被配置为旋转所述至少一个磁体的马达, 外部调节装置的至少一个磁体实现可调节植入物的永磁体的旋转运动并改变可调节植入物的尺寸。 该系统包括被配置为驱动外部调节装置的电动机以实现可调节植入物的目标尺寸的驱动控制电路。