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1. 发明授权

US08137346B2 Electrosurgical lesion location device 有权
标题翻译：电外科病变位置装置
公开(公告)号：US08137346B2
公开(公告)日：2012-03-20
申请号：US11890329
申请日：2007-08-06
申请人： Fred H. Burbank , Frank R. Louw , Paul Lubock , Richard L. Quick
发明人： Fred H. Burbank , Frank R. Louw , Paul Lubock , Richard L. Quick
IPC分类号： A61B18/18
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A device for localizing a target tissue mass in a body includes a tubular trocar portion having a distal end and a proximal end portion that is removably attachable to a handle portion. The trocar portion contains at least a first plurality of locator wires that are movable between a retracted position within the trocar and a deployed position extending radially from the trocar. The first plurality of locator wires mounted for axial movement within the trocar portion between a proximal retracted position and a deployed distal position. The second plurality of locator wires is mounted for movement between a distal retracted position and a proximal deployed position. The locator wires are electrically energized to facilitate their deployment electrosurgically.
摘要翻译：用于使身体中的目标组织块定位的装置包括管状套管针部分，其具有可拆卸地附接到手柄部分的远端和近端部分。套针针部分包含至少第一组多个定位线，其可在套管针内的缩回位置和从套管针径向延伸的展开位置之间移动。第一组多个定位线安装用于在套管针部分内在近端缩回位置和展开的远侧位置之间轴向移动。第二组多个定位线被安装用于在远端缩回位置和近端展开位置之间移动。定位器电线通电，以方便他们在电外科手术。

2. 发明授权

US08718745B2 Tissue site markers for in vivo imaging 有权
标题翻译：用于体内成像的组织位点标记
公开(公告)号：US08718745B2
公开(公告)日：2014-05-06
申请号：US12787177
申请日：2010-05-25
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick , Frank R. Louw , Stephen A. DeSantis
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick , Frank R. Louw , Stephen A. DeSantis
IPC分类号： A61B6/00
CPC分类号： A61B19/54 , A61B6/12 , A61B8/0833 , A61B90/39 , A61B2090/08021 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61B2090/3991 , A61M37/0069
摘要： An intracorporeal site marker has high ultrasound reflectivity, presents a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The biopsy site marker may include features to fix the marker to the biopsy site so as to resist migration from the biopsy cavity.
摘要翻译：体内位点标记物具有高超声反射率，从小标记物提供了显着的声学特征，以避免在随后的成像研究中模糊诊断组织特征，并且可以容易地与生物学特征区别开来。活检部位标记可以包括将标记物固定到活检部位以防止从活检腔迁移的特征。

3. 发明申请

US20100298698A1 TISSUE SITE MARKERS FOR IN VIVO IMAGING 有权
标题翻译：组织网站标记在VIVO成像
公开(公告)号：US20100298698A1
公开(公告)日：2010-11-25
申请号：US12787177
申请日：2010-05-25
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick , Frank R. Louw , Stephen A. DeSantis
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick , Frank R. Louw , Stephen A. DeSantis
IPC分类号： A61B6/00
CPC分类号： A61B19/54 , A61B6/12 , A61B8/0833 , A61B90/39 , A61B2090/08021 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61B2090/3991 , A61M37/0069
摘要： The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.
摘要翻译：本发明是针对活检部位标记和标记活检部位的方法，使得活检腔的位置通过常规成像方法，特别是通过超声成像容易看到。本发明的活检部位标记物具有高的超声反射率，从小标记物呈现出实质的声学特征，以避免在随后的成像研究中掩盖诊断组织特征，并且可以容易地与生物特征区别开来。本发明的活检部位标记物的几个公开的实施方案具有放置在组织部位中的声阻抗的高对比度，以便有效地反射和散射超声能量，并且优选地包括气体填充的内部孔。标记可以具有不均匀的表面轮廓以增强声学特征。标记具有在医学成像期间可识别人造的特征形式。可以将活检部位标记物精确地固定到活检部位，以便当放置放置器械被取出时以及随后移动或操纵标记的组织时抵抗活组织腔的迁移。

4. 发明授权

US07261712B2 Electrosurgical lesion location device 有权
标题翻译：电外科病变位置装置
公开(公告)号：US07261712B2
公开(公告)日：2007-08-28
申请号：US09967755
申请日：2001-09-28
申请人： Fred H. Burbank , Frank R. Louw , Paul Lubock , Richard L. Quick
发明人： Fred H. Burbank , Frank R. Louw , Paul Lubock , Richard L. Quick
IPC分类号： A61B18/18
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A device for localizing a target tissue mass in a body includes a tubular trocar portion having a distal end and a proximal end portion that is removably attachable to a handle portion. The trocar portion contains at least a first plurality of locator wires that are movable between a retracted position within the trocar and a deployed position extending radially from the trocar. In a preferred embodiment, the trocar portion has an electrosurgical cutting element at its distal end, and first and second pluralities of locator wires that, when deployed, respectively define first and second locating perimeters.
摘要翻译：用于使身体中的目标组织块定位的装置包括管状套管针部分，其具有可拆卸地附接到手柄部分的远端和近端部分。套针针部分包含至少第一组多个定位线，其可在套管针内的缩回位置和从套管针径向延伸的展开位置之间移动。在优选实施例中，套管针部分在其远端具有电外科切割元件，以及当展开时分别限定第一和第二定位周边的第一和第二多个定位线。

5. 发明授权

US06312429B1 Electrosurgical lesion location device 失效
公开(公告)号：US06312429B1
公开(公告)日：2001-11-06
申请号：US09356187
申请日：1999-07-16
申请人： Fred H. Burbank , Frank R. Louw , Paul Lubock , Richard L. Quick
发明人： Fred H. Burbank , Frank R. Louw , Paul Lubock , Richard L. Quick
IPC分类号： A61B1818
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A device for localizing a target tissue mass in a body includes a tubular trocar portion having a distal end and a proximal end portion that is removably attachable to a handle portion. The trocar portion contains at least a first plurality of locator wires that are movable between a retracted position within the trocar and a deployed position extending radially from the trocar. In a preferred embodiment, the trocar portion has an electrosurgical cutting element at its distal end, and first and second pluralities of locator wires that, when deployed, respectively define first and second locating perimeters. The first plurality of locator wires is connected to a first wire carrying member longitudinally mounted for axial movement within the trocar portion between a proximal position corresponding to the retracted position of the first plurality of locator wires, and a distal position corresponding to the deployed position of the first plurality of locator wires. The second plurality of locator wires is connected to a second wire-carrying member longitudinally mounted in the trocar portion, coaxially with the first tubular member, for movement between a distal position corresponding to the retracted position of the second plurality of locator wires, and a proximal position corresponding to the deployed position of the second plurality of locator wires. The trocar portion has an intermediate portion having first and second pluralities of slot-shaped apertures through which the first and second pluralities of locator wires emerge when moved to their respective deployed positions. With the locator wires in their retracted position, the trocar is passed through a target tissue mass until the intermediate portion is within the mass. The locator wires are then deployed within the mass to anchor the trocar therein and to mark the site for a surgical procedure. In the preferred embodiment, the locator wires are electrically energized to facilitate their deployment electrosurgically.

6. 发明授权

US06958044B2 Methods and apparatus for securing medical instruments to desired locations in a patient's body 有权
公开(公告)号：US06958044B2
公开(公告)日：2005-10-25
申请号：US10004987
申请日：2001-12-04
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
IPC分类号： A61B10/02 , A61B10/00 , A61B17/00 , A61B17/22 , A61B17/32 , A61B17/34 , A61B18/12 , A61B18/14 , A61B19/00 , A61F2/82
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2019/5487 , A61B2019/5491 , A61B2090/3908 , A61B2090/3991
摘要： Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.

7. 发明授权

US06344026B1 Tissue specimen encapsulation device and method thereof 有权
标题翻译：组织标本包封装置及其方法
公开(公告)号：US06344026B1
公开(公告)日：2002-02-05
申请号：US09208535
申请日：1998-12-09
申请人： Fred H. Burbank , Richard L. Quick , Jacob Frank Louw , Michael L. Jones , Paul Lubock
发明人： Fred H. Burbank , Richard L. Quick , Jacob Frank Louw , Michael L. Jones , Paul Lubock
IPC分类号： A61B500
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00234 , A61B17/221 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1487 , A61B18/1492 , A61B90/37 , A61B2017/00287 , A61B2017/2212 , A61B2017/320064 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A device for encapsulating tissue specimens includes a wand assembly, a sheath, and a guide assembly. The guide assembly pulls, draws, or otherwise moves the sheath about the tissue specimen. The wand assembly is disposed proximate to the tissue specimen, typically either adjacent or through the specimen. In an aspect of the encapsulating device, the guide assembly has sheath deployment members that are disposed about the tissue specimen. The sheath, which is attached to ends of the sheath deployment members and the wand assembly, is drawn over the tissue specimen as the sheath deployment members are pushed or pulled. In another aspect of the device, the guide assembly is an arm or a housing that rotates about the tissue specimen. The sheath, which is secured at one end to the guide assembly and at another end to the wand assembly, is drawn over the tissue specimen as the guide assembly rotates. The sheath may be made up of porous material, non-porous material, selectively permeable material, woven material, braided material, knit material, web material, mesh material, a film material, a flexible laminate material, or of an elastic material.
摘要翻译：用于封装组织样本的装置包括棒组件，护套和引导组件。引导组件拉动，牵引或以其他方式使护套围绕组织标本移动。棒组件靠近组织标本设置，通常是相邻的或通过样本。在封装装置的一个方面中，引导组件具有围绕组织标本设置的护套展开部件。当护套展开构件被推动或拉动时，附接到鞘展开构件和杆组件的端部的护套被拉过组织标本。在装置的另一方面，导向组件是围绕组织标本旋转的臂或壳体。当引导组件旋转时，在一端固定到引导组件并且另一端固定到杆组件的护套在组织样本上被拉伸。护套可以由多孔材料，无孔材料，选择性渗透材料，编织材料，编织材料，针织材料，纤维网材料，网状材料，薄膜材料，柔性层压材料或弹性材料制成。

8. 发明授权

US06261241B1 Electrosurgical biopsy device and method 有权
公开(公告)号：US06261241B1
公开(公告)日：2001-07-17
申请号：US09159467
申请日：1998-09-23
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
IPC分类号： A61B1000
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B2010/0208 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： An electrosurgical biopsy device includes a stylet and a cannula movably mounted on a base. The stylet has a shaft with a head at its distal end and a stylet ablation element extending distally from the head. The stylet shaft is disposed through the cannula for axial translation therein between withdrawn and extended positions. The cannula has an opening at its distal end and a cannula ablation element adjacent the opening. Both ablation elements are activatable with energy that ablates adjacent tissue. A translation mechanism controllably moves (a) the stylet between the withdrawn and extended positions and (b) the cannula between a proximal position and a distal position relative to the base. In use, with the stylet in the withdrawn position against the distal end of the cannula, and with the stylet ablation element activated, the stylet and the cannula are pushed through the skin and the underlying tissue until the stylet head is adjacent a targeted tissue mass. Next, the stylet is extended distally from the distal end of the cannula so that its head penetrates the tissue mass. The cannula ablation element is then activated, and the cannula is pushed through the tissue mass toward the stylet head, thereby cutting a “core” through the tissue mass that is captured as a tissue specimen within the distal end of the cannula. The cannula and the stylet are then removed from the patient's body.

9. 发明授权

US09216012B2 Methods and apparatus for securing medical instruments to desired locations in a patient's body 有权
标题翻译：将医疗器械固定在患者身体所需位置的方法和装置
公开(公告)号：US09216012B2
公开(公告)日：2015-12-22
申请号：US13543309
申请日：2012-07-06
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
IPC分类号： A61B10/02 , A61B17/32 , A61B17/00 , A61B17/3205 , A61B18/14 , A61B17/3207 , A61B17/34 , A61B19/00 , A61B18/00 , A61B18/12 , A61B18/16
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2019/5487 , A61B2019/5491 , A61B2090/3908 , A61B2090/3991
摘要： A medical device for localization of tissue at a target site in a patient's body includes a tube having a distal end, a proximal end, and a longitudinal axis. The medical device is configured for placement of the distal end at the target site. A fixation device is disposed on the distal end. The affixation device is configured to mechanically fix the distal end of the medical device to tissue at the target site.
摘要翻译：用于在患者体内的靶部位定位组织的医疗装置包括具有远端，近端和纵向轴线的管。医疗装置被配置为将远端放置在目标位置处。固定装置设置在远端。固定装置构造成将医疗装置的远端机械地固定在目标部位的组织。

10. 发明授权

US08229553B2 Methods and apparatus for securing medical instruments to desired locations in a patient's body 有权
标题翻译：将医疗器械固定在患者身体所需位置的方法和装置
公开(公告)号：US08229553B2
公开(公告)日：2012-07-24
申请号：US11059992
申请日：2005-02-17
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
IPC分类号： A61B5/04
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2019/5487 , A61B2019/5491 , A61B2090/3908 , A61B2090/3991
摘要： Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.
摘要翻译：提供了设备和方法，用于使用固定剂将医疗器械牢固地固定在患者体内的期望的组织上。这样的医疗器械可以包括定位线或组织采集器械，例如活检器械。在组织采集仪器的情况下，本发明人已经发现了将组织采集仪器的远端牢固地固定到特定组织靶区域的显着优点。例如，这种方法允许成像环境与程序环境分离，从而不需要使用诸如立体定向成像设备之类的昂贵和经常不可用的成像设备。在优选的实施方案中，使用粘合剂，例如粘合剂，手术胶或溶剂作为固定剂。

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