专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20080089905A1 COMPOUNDS FOR STIMULATING STEM CELL PROLIFERATION INCLUDING AFA-OMEGA (EtOH) 审中-公开
标题翻译：用于刺激包括AFA-OMEGA（EtOH）的干细胞增殖的化合物
公开(公告)号：US20080089905A1
公开(公告)日：2008-04-17
申请号：US11757251
申请日：2007-06-01
申请人： Cyndy Davis Sanberg , Paula Bickford , Paul Sanberg , Jun Tan , R. Shytle , Jerry Anderson
发明人： Cyndy Davis Sanberg , Paula Bickford , Paul Sanberg , Jun Tan , R. Shytle , Jerry Anderson
IPC分类号： A61K36/05 , A61K36/45 , A61K36/82 , A61P43/00
CPC分类号： A61K31/205 , A61K31/59 , A61K35/748 , A61K36/45 , A61K36/82 , A61K2300/00
摘要： A method and composition for stimulating the proliferation and differentiation of stem cells is used to self-repair injury in mammals. A supplement is administered having an effective dose of substances selected from blueberry, carnosine, catechin, green tea extract, VitaBlue, Vitamin D3, Spirulina, AFA or effective combinations and derivatives of these. For example, a supplement comprising wild blueberry, green tea extract, carnosine, vitamin D3, and AFA-Omega (EtOH) or Spirulina and AFA-Omega (EtOH) exhibits a synergistic and unexpected association with substantially increased proliferation of bone marrow stem cells and CD34+. A therapeutic amount of a substance that is associated with a substantial increase in stem cells may be used to prevent and repair damaged tissues of the brain, due to stroke, the heart, due to coronary artery disease or a heart attack.
摘要翻译：用于刺激干细胞增殖和分化的方法和组合物用于自我修复哺乳动物的损伤。施用补充物，其具有选自蓝莓，肌肽，儿茶素，绿茶提取物，维生素B，维生素D3，螺旋藻，AFA中的有效剂量的物质或这些的有效组合和衍生物。例如，包含野生蓝莓，绿茶提取物，肌肽，维生素D3和AFA-Omega（EtOH）或螺旋藻和AFA-Omega（EtOH）的补充物显示出与骨髓干细胞的增殖显着增加的协同和意想不到的关联， CD34 +。可以使用与干细胞显着增加相关的物质的治疗量来预防和修复由于冠状动脉疾病或心脏病发作引起的脑中风，心脏的受损组织。

2. 发明申请

US20080085330A1 COMPOUNDS FOR STIMULATING STEM CELL PROLIFERATION INCLUDING SPIRULINA 审中-公开
标题翻译：用于刺激包括螺旋体的干细胞增殖的化合物
公开(公告)号：US20080085330A1
公开(公告)日：2008-04-10
申请号：US11757266
申请日：2007-06-01
申请人： Cyndy Davis Sanberg , Paula Bickford , Paul Sanberg , Jun Tan , R. Shytle
发明人： Cyndy Davis Sanberg , Paula Bickford , Paul Sanberg , Jun Tan , R. Shytle
IPC分类号： A61K36/82 , A61K36/45 , A61P43/00
CPC分类号： A61K31/205 , A61K31/59 , A61K35/748 , A61K36/45 , A61K36/82 , A61K2300/00
摘要： A method and composition for stimulating the proliferation and differentiation of stem cells is used to self-repair injury in mammals. A supplement is administered having an effective dose of substances selected from blueberry, carnosine, catechin, green tea extract, VitaBlue, Vitamin D3, Spirulina, AFA or effective combinations and derivatives of these. For example, a supplement comprising wild blueberry, green tea extract, carnosine, vitamin D3, and a Spirulina and/or an AFA-Omega (EtOH) exhibited a synergistic and unexpected association with substantially increased proliferation of bone marrow stem cells and CD34+. A therapeutic amount of a substance that is associated with a substantial increase in stem cells may be used to prevent and repair damages tissues of the brain, due to stroke, the heart, due to coronary artery disease or a heart attack.
摘要翻译：用于刺激干细胞增殖和分化的方法和组合物用于自我修复哺乳动物的损伤。施用补充剂，其具有选自蓝莓，肌肽，儿茶素，绿茶提取物，维生素B，维生素D 3，螺旋藻，AFA或其有效组合和衍生物的有效剂量的物质。例如，包含野生蓝莓，绿茶提取物，肌肽，维生素D 3和螺旋藻和/或AFA-Omega（EtOH）的补充物显示与骨髓干细胞和CD34的增加的显着增加的协同和意想不到的关联 +。可以使用治疗量的与干细胞显着增加相关的物质来预防和修复由于冠状动脉疾病或心脏病发作引起的脑中风，心脏损伤的组织。

3. 发明申请

US20060275512A1 Combined effects of nutrients on proliferation of stem cells 有权
公开(公告)号：US20060275512A1
公开(公告)日：2006-12-07
申请号：US11415907
申请日：2006-05-02
申请人： Cyndy Davis Sanberg , Paul Sanberg , Paula Bickford , R. Shytle , Jun Tan
发明人： Cyndy Davis Sanberg , Paul Sanberg , Paula Bickford , R. Shytle , Jun Tan
IPC分类号： A61K36/82 , A61K36/45 , A61K31/59 , A61K31/205
CPC分类号： A61K31/59 , A61K31/205 , A61K36/45 , A61K36/82 , A61K2300/00
摘要： A method and composition for stimulating the proliferation and differentiation of stem cells is used to self-repair injury in mammals. A supplement is administered having an effective dose of blueberry, carnosine, catechin, green tea extract, VitaBlue, Vitamin D3 or combinations of these. For example, a therapeutic amount of two or more of the supplements may be selected having a synergistic effect, allowing a lower dose to achieve the same or greater effective protection as a higher dose of any one of the supplements.

4. 发明申请

US20080033038A1 Compositions of polyphenols and methods of use 审中-公开
标题翻译：多酚的组成和使用方法
公开(公告)号：US20080033038A1
公开(公告)日：2008-02-07
申请号：US11825346
申请日：2007-07-05
申请人： R. Shytle , Jun Tan
发明人： R. Shytle , Jun Tan
IPC分类号： A61K31/352 , A61P11/00 , A61P25/00 , A61P29/00 , A61P31/00 , A61P37/00
CPC分类号： A61K31/353 , A61K31/05
摘要： The subject invention concerns materials and methods for treating or preventing any condition or disease that is treatable by a green tea polyphenol, or an analog, isomer, metabolite, or prodrug thereof, wherein the polyphenol is administered as an intranasal formulation to a person or animal in need of treatment. In one embodiment, the intranasal polyphenol formulation comprises (−)-epigallocatechin-3-gallate (EGCG) and epicatechin (EC), two polyphenols derived from green tea and other plants and that can be produced synthetically. The subject invention also concerns materials and methods for treating or preventing dementia, such as AIDS-dementia in a person or animal by administering a therapeutically effective amount of a polyphenol, or an analog, isomer, metabolite, or prodrug thereof. In one embodiment, a composition of the invention increases expression or activity of a protein that exhibits α-secretase activity.
摘要翻译：本发明涉及用于治疗或预防可由绿茶多酚或其类似物，异构体，代谢物或前药治疗的任何病症或疾病的材料和方法，其中所述多酚以鼻内制剂施用于人或动物需要治疗。在一个实施方案中，鼻内多酚制剂包含（ - ） - 表没食子儿茶酚-3-没食子酸酯（EGCG）和表儿茶素（EC），两种来自绿茶和其他植物的多酚，可以合成制备。本发明还涉及通过施用治疗有效量的多酚或其类似物，代谢物或前药来治疗或预防痴呆的物质和方法，例如人或动物的AIDS-痴呆症。在一个实施方案中，本发明的组合物增加显示α-分泌酶活性的蛋白质的表达或活性。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式