专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06955171B1 System and method for delivering therapeutic gas to a patient 失效
标题翻译：将治疗气体输送给患者的系统和方法
公开(公告)号：US06955171B1
公开(公告)日：2005-10-18
申请号：US10140304
申请日：2002-05-07
申请人： Curtis Figley , Darin W. Hunt , Christopher C. Miller
发明人： Curtis Figley , Darin W. Hunt , Christopher C. Miller
IPC分类号： A61M16/00 , A61M16/06 , A61M16/20
CPC分类号： A61M16/0816 , A61M16/0051 , A61M16/024 , A61M16/0677 , A61M16/203 , A61M16/208 , A61M16/209 , A61M2016/0027 , A61M2016/0039 , A61M2016/0042 , A61M2202/0275 , A61M2205/6018 , A61M2205/6027 , A61M2205/8206 , A61M2205/8237 , Y10T137/7808
摘要： Therapeutic gas, such as NO, is delivered to a patient in accurately controlled amounts by a system that uses a closed loop feedback system in which the amount of therapeutic gas delivered is a precise fraction of the total gas delivered to the patient. Ratiometric feedback is used in the control loop.
摘要翻译：诸如NO的治疗气体通过使用闭环反馈系统的系统以精确控制的量递送给患者，其中输送的治疗气体的量是输送到患者的总气体的精确分数。控制回路中使用比例反馈。

2. 发明授权

US06668828B1 System and elements for managing therapeutic gas administration to a spontaneously breathing non-ventilated patient 有权
标题翻译：用于管理治疗气体给自发呼吸的非通气患者的系统和元件
公开(公告)号：US06668828B1
公开(公告)日：2003-12-30
申请号：US09688229
申请日：2000-10-16
申请人： Curtis B. Figley , Darin W. Hunt , Christopher C. Miller
发明人： Curtis B. Figley , Darin W. Hunt , Christopher C. Miller
IPC分类号： A61M1600
CPC分类号： A61M16/0816 , A61M16/0051 , A61M16/024 , A61M16/0677 , A61M16/203 , A61M16/208 , A61M16/209 , A61M2016/0027 , A61M2016/0039 , A61M2016/0042 , A61M2202/0275 , A61M2205/6018 , A61M2205/6027 , A61M2205/8206 , A61M2205/8237 , Y10T137/7808
摘要： A system controls and manages administration of a therapeutic gas, such as NO, O2, or the like, to a spontaneously breathing, non-ventilated patient such that concentrated NO is as low as reasonably possible while delivering the desired amount of NO to the distal portions of the lungs. The system includes an entrainment cell that provides remote, turbulent mixing with low temporal latency and can be used with a nasal cannula or a mask. The entrainment cell uses room air to dilute the therapeutic gas; however, supplementary gases can also be used. A baffle can be included to promote mixing and a flow sensor can also be used if desired. Multiple ports can be included in the entrainment cell. An equalizing valve is also disclosed.
摘要翻译：系统控制和管理诸如NO，O 2等的治疗气体的给药给自发呼吸的非通气患者，使得浓缩的NO尽可能低，同时将期望量的NO递送到远端部分肺部。该系统包括夹带细胞，其提供具有低时间潜伏期的远程湍流混合，并且可以与鼻插管或面罩一起使用。夹带细胞使用室内空气稀释治疗气体; 然而，也可以使用补充气体。可以包括挡板以促进混合，并且如果需要也可以使用流量传感器。夹带单元中可以包含多个端口。还公开了一种均衡阀。

3. 发明授权

US06986351B2 System and elements for managing therapeutic gas administration to a spontaneously breathing non-ventilated patient 失效
标题翻译：用于管理治疗气体给自发呼吸的非通气患者的系统和元件
公开(公告)号：US06986351B2
公开(公告)日：2006-01-17
申请号：US10691649
申请日：2003-10-24
申请人： Curtis B. Figley , Darin W. Hunt , Christopher C. Miller
发明人： Curtis B. Figley , Darin W. Hunt , Christopher C. Miller
IPC分类号： A62B7/00 , A62B7/10 , A62B9/02 , F16K31/00 , F16K31/12
CPC分类号： A61M16/0816 , A61M16/0051 , A61M16/024 , A61M16/0677 , A61M16/203 , A61M16/208 , A61M16/209 , A61M2016/0027 , A61M2016/0039 , A61M2016/0042 , A61M2202/0275 , A61M2205/6018 , A61M2205/6027 , A61M2205/8206 , A61M2205/8237 , Y10T137/7808
摘要： A system controls and manages administration of a therapeutic gas, such as NO, O2, or the like, to a spontaneously breathing, non-ventilated patient such that concentrated NO is as low as reasonably possible while delivering the desired amount of NO to the distal portions of the lungs. The system includes an entrainment cell that provides remote, turbulent mixing with low temporal latency and can be used with a nasal cannula or a mask. The entrainment cell uses room air to dilute the therapeutic gas; however, supplementary gases can also be used. A baffle can be included to promote mixing and a flow sensor can also be used if desired. Multiple ports can be included in the entrainment cell. An equalizing valve is also disclosed.
摘要翻译：系统控制和管理诸如NO，O 2等的治疗气体的给药到自发呼吸的非通气患者，使得浓缩NO在合理可能的情况下尽可能低，同时递送对肺的远端部分的NO的期望量。该系统包括夹带细胞，其提供具有低时间潜伏期的远程湍流混合，并且可以与鼻插管或面罩一起使用。夹带细胞使用室内空气稀释治疗气体; 然而，也可以使用补充气体。可以包括挡板以促进混合，并且如果需要也可以使用流量传感器。夹带单元中可以包含多个端口。还公开了一种均衡阀。

4. 发明授权

US09186148B2 Tissue stapler anvil feature to prevent premature jaw opening 有权
标题翻译：组织吻合器砧特点，以防止过早的颚开口
公开(公告)号：US09186148B2
公开(公告)日：2015-11-17
申请号：US13344061
申请日：2012-01-05
申请人： Kevin D. Felder , John F. Cummings , Joseph P. Schowalter , Patrick J. Swindon , Johnny H. Alexander, III , Patrick A. Weizman , Cory G. Kimball , Edward G. Chekan , Joseph E. Young , Christopher C. Miller , Barry T. Jamison , John V. Hunt , Kent P. Baker , Cortney E. Henderson , Chester O. Baxter, III , Jerome R. Morgan , Adam R. Dunki-Jacobs , Venkataramanan Mandakolathur Vasudevan , Carl J. Shurtleff , Julia F. Serber
发明人： Kevin D. Felder , John F. Cummings , Joseph P. Schowalter , Patrick J. Swindon , Johnny H. Alexander, III , Patrick A. Weizman , Cory G. Kimball , Edward G. Chekan , Joseph E. Young , Christopher C. Miller , Barry T. Jamison , John V. Hunt , Kent P. Baker , Cortney E. Henderson , Chester O. Baxter, III , Jerome R. Morgan , Adam R. Dunki-Jacobs , Venkataramanan Mandakolathur Vasudevan , Carl J. Shurtleff , Julia F. Serber
IPC分类号： A61B17/068 , A61B17/115 , A61B17/072 , A61B17/00 , A61B17/29 , A61B19/00
CPC分类号： A61B17/064 , A61B17/0686 , A61B17/072 , A61B17/07207 , A61B17/115 , A61B17/1155 , A61B2017/00876 , A61B2017/07214 , A61B2017/0725 , A61B2017/2946 , A61B2090/0811
摘要： A surgical instrument includes a handle assembly having a trigger operable to fire a staple driver to staple tissue. The instrument includes a pointed rod to which an anvil may be coupled. An anvil detection feature is included to determine when the anvil is coupled to the rod. In some versions, the anvil detection feature comprises a translatable rod that inhibits a lockout feature from disengaging. In other versions, an anvil sensing tube is disposed about the pointed rod and interferes with actuation of the trigger in a first position. A recess in the tube permits trigger to actuate when the anvil sensing tube is in the second position. Alternatively, a resilient tab is coupled to the pointed rod and resists actuation of the staple driver. A trigger lockout assembly may include a spring-loaded button that “pops” out when a push rod is actuated, thereby freeing a pivotable lockout feature.
摘要翻译：一种手术器械包括具有触发器的手柄组件，该触发器可操作以将钉子驱动器射击至钉组织。该仪器包括可连接砧座的尖杆。包括砧检测功能以确定砧座何时与杆连接。在一些形式中，砧座检测特征包括一个能够阻止锁定特征脱离的可平移杆。在其他形式中，砧感知管围绕尖的杆设置并且在第一位置上干扰触发器的致动。当砧座感测管处于第二位置时，管中的凹部允许触发器致动。或者，弹性突舌连接到尖的杆并抵抗钉驱动器的致动。触发器锁定组件可以包括弹簧加载的按钮，当按压推杆时“弹出”按钮，从而释放可枢转的锁定特征。

5. 发明申请

US20150297782A1 NITRIC OXIDE-RELEASING DRESSINGS 审中-公开
标题翻译：硝酸氧化物发酵
公开(公告)号：US20150297782A1
公开(公告)日：2015-10-22
申请号：US14585008
申请日：2014-12-29
申请人： Christopher C. Miller , Bruce Murray
发明人： Christopher C. Miller , Bruce Murray
IPC分类号： A61L15/44 , A61L15/20 , A61F13/00 , A43B17/00 , A43B7/00 , A61L15/18 , A41B11/00
CPC分类号： A61L15/44 , A41B11/005 , A41B2400/34 , A43B1/0045 , A43B7/00 , A43B7/1455 , A43B17/003 , A43B17/03 , A61F13/00063 , A61F2013/00285 , A61K31/194 , A61K33/00 , A61L15/18 , A61L15/20 , A61L15/46 , A61L2300/114 , A61L2300/404 , A61L2300/602 , A61L2300/608 , A61K2300/00
摘要： A wound dressing comprising nitric oxide gas producing component.
摘要翻译：包含一氧化氮气体产生组分的伤口敷料。

6. 发明申请

US20120108893A1 DEPLOYABLE AND RETRACTABLE MEMBER FOR INJECTION PORT 有权
标题翻译：注射口可配合和可退回的会员
公开(公告)号：US20120108893A1
公开(公告)日：2012-05-03
申请号：US12938719
申请日：2010-11-03
申请人： Christopher C. Miller
发明人： Christopher C. Miller
IPC分类号： A61F2/00
CPC分类号： A61M39/0208 , A61F5/0056
摘要： An apparatus comprises a housing and one or more deployable protrusions. The apparatus defines a fluid reservoir and presents an upper surface. The housing is sized and configured to be implanted within a patient. The protrusions are selectively movable from a first position to a second position. The protrusions are at least partially retracted relative to the housing when the protrusions are in the first position. The protrusions are at least partially extended relative to the housing when the protrusions are in the second position. The protrusions may be in the form of substantially cylindraceous posts, semi-circular members, or other shapes. The protrusions may be actuated mechanically, electromechanically, or otherwise. The apparatus may be provided as an injection port, as part of a gastric band system or otherwise. The deployed protrusions may facilitate location of the implanted port through external palpation of the patient's abdomen.
摘要翻译：一种装置包括壳体和一个或多个可部署突起。该装置限定流体储存器并呈现上表面。外壳的尺寸和构造被植入患者体内。突起可以选择性地从第一位置移动到第二位置。当突起处于第一位置时，突起至少部分地相对于壳体缩回。当突起处于第二位置时，突起至少部分地相对于壳体延伸。突起可以是基本上圆柱形的柱，半圆形构件或其它形状的形式。突起可以机械地，机电地或其他方式致动。该装置可以被提供为注射端口，作为胃束带系统的一部分或以其它方式。部署的突起可以通过患者腹部的外部触诊来促进植入端口的位置。

7. 发明授权

US09603599B2 Feature to reengage safety switch of tissue stapler 有权
公开(公告)号：US09603599B2
公开(公告)日：2017-03-28
申请号：US13328344
申请日：2011-12-16
申请人： Christopher C. Miller , Edward G. Chekan , Johnny H. Alexander, III , John F. Cummings , Carl J. Shurtleff , Adam R. Dunki-Jacobs , Barry T. Jamison , Joseph E. Young , Cortney E. Henderson
发明人： Christopher C. Miller , Edward G. Chekan , Johnny H. Alexander, III , John F. Cummings , Carl J. Shurtleff , Adam R. Dunki-Jacobs , Barry T. Jamison , Joseph E. Young , Cortney E. Henderson
IPC分类号： A61B17/068 , A61B17/115
CPC分类号： A61B17/1155 , A61B17/115 , A61B2017/00367 , A61B2017/00407 , A61B2017/00862 , A61B2090/034 , A61B2090/0811
摘要： A surgical instrument includes an anvil selectively coupleable to a stapling head assembly and a trigger operable to fire staples into tissue compressed between the anvil and the stapling head assembly. In some versions, a lockout member may engage a securing feature to prevent actuation of the anvil relative to the stapling head assembly. For instance, a tab may engage a slot on an actuator, a screen door lock may provide frictional resistance or engage teeth on the actuator, a door may actuate into engagement with one or more recesses, geared teeth may mesh with teeth on the actuator, the lockout member may include a ratcheting assembly to engage actuator, and/or a push button may actuate into a recess while disengaging the lockout member. Alternatively, in some versions, the trigger actuation assembly may be disengaged prior to firing. An anvil position indicator may restrict engagement of the trigger actuation assembly.

8. 发明授权

US08795222B2 Device and method for treatment of surface infections with nitric oxide 有权
标题翻译：用一氧化氮治疗表面感染的装置和方法
公开(公告)号：US08795222B2
公开(公告)日：2014-08-05
申请号：US13006218
申请日：2011-01-13
申请人： Alex Stenzler , Christopher C. Miller
发明人： Alex Stenzler , Christopher C. Miller
IPC分类号： A61M37/00 , A61M1/00 , A01N59/02
CPC分类号： A61M35/00 , A61B90/40 , A61H33/14 , A61K33/00 , A61L2/0094 , A61L15/18 , A61L15/44 , A61L2300/114 , A61L2300/602 , A61M1/0031 , A61M1/0088 , A61M13/003 , A61M13/006 , A61M2202/0275 , A61M2205/3334 , A61K2300/00
摘要： Topical exposure of nitric oxide gas to wounds such as chronic non-healing wounds may be beneficial in promoting healing of the wound and in preparing the wound bed for further treatment and recovery. Nitric oxide gas may be used, for example, to reduce the microbial infection and burden on these wounds, manage exudate secretion by reducing inflammation, upregulate expression of endogenous collagenase to locally debride the wound, and regulate the formation of collagen. High concentration of nitric oxide ranging from about 160 to 400 ppm may be used without inducing toxicity in the healthy cells around a wound site. Additionally, exposure to the high concentration for a first treatment period reduces the microbial burden and inflammation at the wound site and increase collagenase expression to debride necrotic tissue at the wound site. After a first treatment period with high concentration of nitric oxide, a second treatment period at a lower concentration of nitric oxide preferably ranging from about 5-20 ppm may to provided to restore the balance of nitric oxide and induce collagen expression to aid in the closure of the wound.
摘要翻译：一氧化氮气体局部暴露于伤口如慢性非愈合伤口可能有益于促进伤口愈合和制备伤口床进一步治疗和恢复。例如，可以使用一氧化氮气体来减少这些伤口的微生物感染和负担，通过减少炎症，上调内源性胶原酶的表达来局部清创伤口并调节胶原的形成来控制渗出物分泌。可以使用约160至400ppm范围内的高浓度一氧化氮，而不会在伤口部位周围的健康细胞中引起毒性。此外，在第一次治疗期间暴露于高浓度可减少伤口部位的微生物负担和炎症，并增加胶原酶表达以清除伤口部位的坏死组织。在具有高浓度一氧化氮的第一次治疗期后，可提供较低浓度的一氧化氮优选约5-20ppm的第二治疗期以恢复一氧化氮的平衡并诱导胶原表达以帮助闭合的伤口。

9. 发明申请

US20130175319A1 TISSUE STAPLER SAFETY SWITCH FEATURE TO PREVENT PREMATURE JAW OPENING 有权
标题翻译：组织安全开关安全切换功能，防止普通打开开关
公开(公告)号：US20130175319A1
公开(公告)日：2013-07-11
申请号：US13344071
申请日：2012-01-05
申请人： Kevin D. Felder , John F. Cummings , Joseph P. Schowalter , Patrick J. Swindon , Johnny H. Alexander, III , Christopher C. Miller , Barry T. Jamison , John V. Hunt , Kent P. Baker , Julia F. Serber
发明人： Kevin D. Felder , John F. Cummings , Joseph P. Schowalter , Patrick J. Swindon , Johnny H. Alexander, III , Christopher C. Miller , Barry T. Jamison , John V. Hunt , Kent P. Baker , Julia F. Serber
IPC分类号： A61B17/068
CPC分类号： A61B17/1155 , A61B2017/2946 , A61B2090/0811
摘要： A surgical stapler comprises an anvil assembly, an anvil shaft, a driver, an actuating arm, a safety switch, and a safety feature. The anvil assembly couples with the anvil shaft. The driver drives a plurality of staples into tissue. The actuating arm is in communication with the surgical stapler and is configured to actuate the driver to drive the plurality of staples into tissue. The safety switch is moveable between a locked and an unlocked position. The safety switch prevents operation of the actuating arm when the safety switch is in the locked position. The safety switch enables operation of the actuating arm when the safety switch is in the unlocked position. The safety feature may prevent operation of the driver even when the safety switch is in the unlocked position or prevent operation of the safety switch.
摘要翻译：手术吻合器包括砧组件，砧座轴，驱动器，致动臂，安全开关和安全特征。砧组件与砧轴相连。驱动器将多个订书钉驱动到组织中。所述致动臂与所述外科缝合器连通并且构造成致动所述驱动器以将所述多个钉驱动到组织中。安全开关可在锁定位置和解锁位置之间移动。当安全开关处于锁定位置时，安全开关可防止操作臂的操作。当安全开关处于未锁定位置时，安全开关可操作执行臂。即使当安全开关处于解锁位置或防止安全开关的操作时，安全功能也可以防止驾驶员的操作。

10. 发明申请

US20200093855A1 ENHANCED IMMUNE RESPONSE UPON TREATMENT WITH NITRIC OXIDE 审中-公开
公开(公告)号：US20200093855A1
公开(公告)日：2020-03-26
申请号：US16430354
申请日：2019-06-03
申请人： Christopher C. Miller , Gilly Regev
发明人： Christopher C. Miller , Gilly Regev
IPC分类号： A61K33/00 , A61K31/365
摘要： The present invention relates to compositions and methods useful for immune activation that is effective for eliciting a non-antigen-specific immune response in a subject. An immunomodulator composition can include a therapeutically effective amount of a liquid nitric oxide releasing solution (NORS) for eliciting an immune response in a subject to treat an adverse health condition in the subject.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式