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1. 发明申请

US20190328562A1 HYBRID STENT AND DELIVERY SYSTEM 审中-公开
公开(公告)号：US20190328562A1
公开(公告)日：2019-10-31
申请号：US16393268
申请日：2019-04-24
申请人： Cook Medical Technologies LLC
发明人： Brent A. Mayle , Ram H. Paul , James C. Merk , Gary Neff , Dean R. Puckett , Austin Neidigh , Thomas Mindel , Michelle Reynolds
IPC分类号： A61F2/958 , A61F2/962 , A61F2/915
摘要： Disclosed herein is a hybrid stent having a balloon-expandable portion joined to a self-expanding portion. The hybrid stent is capable of withstanding the forces applied by delivery. Delivery systems for deploying a hybrid stent are described, as are methods of using such delivery systems.

2. 发明申请

US20140081387A1 TAPERED LOADING SYSTEM FOR IMPLANTABLE MEDICAL DEVICES 审中-公开
标题翻译：用于可植入医疗器械的切割加载系统
公开(公告)号：US20140081387A1
公开(公告)日：2014-03-20
申请号：US14076749
申请日：2013-11-11
申请人： Cook Medical Technologies LLC
发明人： Jeffry S. Melsheimer , Sean D. Chambers , Arman H. Valaie , Ram H. Paul
IPC分类号： A61F2/00
CPC分类号： A61F2/0095 , A61F2/95 , A61F2002/9522 , Y10T29/53
摘要： Loading systems for compressing and loading an implantable medical device into a device chamber of a medical device delivery system are described. The loading systems include an elongate holding chamber within which the intraluminal medical device is disposed. A plunger has one or more attached pushers adapted to axially advance the intraluminal medical device through an intermediate portion of the holding chamber that has a tapered surface, which compresses the intraluminal medical device over a dilator of a medical device delivery system that has been introduced through the distal end of the elongate holding chamber. The elongate holding chamber can be placed within an outer storage container with an appropriate seal to for storage of the intraluminal medical device within the loading system. Methods of preparing an intraluminal medical device for implantation in a patient and kits useful in such methods are also described.
摘要翻译：描述了用于将可植入医疗装置压缩和装载到医疗装置输送系统的装置室中的装载系统。装载系统包括细长的保持室，其中设置管腔内医疗装置。柱塞具有一个或多个附接的推动器，其适于轴向前进管腔内医疗装置通过具有锥形表面的保持室的中间部分，该锥形表面压缩管腔内医疗装置通过已经被引入的医疗装置输送系统的扩张器细长保持室的远端。细长保持室可以放置在具有适当密封件的外部存储容器内，以便将管腔内医疗装置储存在装载系统内。还描述了制备用于植入患者的管腔内医疗装置的方法和用于这些方法的试剂盒。

3. 发明授权

US10143544B2 Low profile intraluminal medical devices 有权
公开(公告)号：US10143544B2
公开(公告)日：2018-12-04
申请号：US14839239
申请日：2015-08-28
申请人： Cook Medical Technologies LLC
发明人： Ram H. Paul , Charles W. Agnew
IPC分类号： A61F2/01
摘要： A low profile intraluminal medical device includes first, second and third wire members that define arcuate paths having only a single sigmoidal curve. Connectors join the wire members. The medical device can be used by itself or as a component in a medical device that includes other components, such as a prosthetic valve, occluder, or filter.

4. 发明授权

US09782191B2 Cutting devices and methods 有权
公开(公告)号：US09782191B2
公开(公告)日：2017-10-10
申请号：US14600336
申请日：2015-01-20
申请人： Cook Medical Technologies LLC
发明人： Joshua F. Krieger , Ram H. Paul , Zachary Berwick
IPC分类号： A61B17/32 , B21F45/00 , A61B17/00
CPC分类号： A61B17/320016 , A61B17/32 , A61B2017/00526 , B21F45/008
摘要： Cutting devices useful for cutting objects or materials are described. Examples of cutting devices useful for creating avulsions in animals, such as human beings, are described. A cutting device includes an elongate main body having proximal and distal ends. A first portion of the main body has a cross-sectional shape that substantially lacks flat surfaces and a second portion of the main body has a cross-sectional shape having one, two or more flat surfaces. The distal end defines a hook having one or more sharpened edges disposed within the notch of the hook. Methods of making cutting devices are also described.

5. 发明授权

US09629704B2 Tapered loading system for implantable medical devices 有权
公开(公告)号：US09629704B2
公开(公告)日：2017-04-25
申请号：US14076749
申请日：2013-11-11
申请人： COOK MEDICAL TECHNOLOGIES LLC
发明人： Jeffry S. Melsheimer , Sean D. Chambers , Arman H. Valaie , Ram H. Paul
IPC分类号： A61F2/95 , A61F2/00
CPC分类号： A61F2/0095 , A61F2/95 , A61F2002/9522 , Y10T29/53
摘要： Loading systems for compressing and loading an implantable medical device into a device chamber of a medical device delivery system are described. The loading systems include an elongate holding chamber within which the intraluminal medical device is disposed. A plunger has one or more attached pushers adapted to axially advance the intraluminal medical device through an intermediate portion of the holding chamber that has a tapered surface, which compresses the intraluminal medical device over a dilator of a medical device delivery system that has been introduced through the distal end of the elongate holding chamber. The elongate holding chamber can be placed within an outer storage container with an appropriate seal to for storage of the intraluminal medical device within the loading system. Methods of preparing an intraluminal medical device for implantation in a patient and kits useful in such methods are also described.

6. 发明申请

US20140155987A1 Low Profile Support Frame and Related Intraluminal Medical Devices 审中-公开
标题翻译：薄型支架和相关腔内医疗器械
公开(公告)号：US20140155987A1
公开(公告)日：2014-06-05
申请号：US14173075
申请日：2014-02-05
申请人： Cook Medical Technologies LLC
发明人： Ram H. Paul , Sean D. Chambers , Charles L. McIntosh , Charles W. Agnew
IPC分类号： A61F2/24 , A61F2/88
CPC分类号： A61F2/2418 , A61F2/01 , A61F2/2412 , A61F2/2475 , A61F2/848 , A61F2/86 , A61F2/88 , A61F2002/016 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2220/0075 , A61F2230/0013 , A61F2230/0021 , A61F2230/0026
摘要： A low profile support frame for use as or in an expandable intraluminal medical device includes first and second wire members that define arcuate paths having opposing curves. Connectors join the wire members. A stabilizing member has a proximal end contained within one of the connectors. The support frame has radially compressed and radially expanded configurations. When the support frame is in the radially expanded configuration, substantially no portion of the support frame is disposed on a first transverse axis of the frame opposite one end of the frame and substantially no portion of the frame is disposed on a second transverse axis of the frame opposite the other end of the frame. The support frame can be used as an intraluminal medical device by itself or as a component in a medical device that includes other components, such as a stent, prosthetic valve, occluder, or filter.
摘要翻译：用于或在可扩展的管腔内医疗装置中使用的低轮廓支撑框架包括限定具有相对曲线的弓形路径的第一和第二线构件。连接器连接线材。稳定构件具有包含在一个连接器内的近端。支撑框架具有径向压缩和径向扩张的构造。当支撑框架处于径向展开构型时，支撑框架的基本上没有部分设置在与框架的一端相对的框架的第一横向轴线上，并且基本上没有框架的任何部分设置在框架的第二横向轴线上框架与框架的另一端相对。支撑框架可以作为管腔内医疗装置本身或作为包括其它部件（例如支架，假体瓣膜，封堵器或过滤器）的医疗装置中的部件使用。

7. 发明授权

US10918408B2 Cutting devices and methods 有权
公开(公告)号：US10918408B2
公开(公告)日：2021-02-16
申请号：US15727791
申请日：2017-10-09
申请人： Cook Medical Technologies LLC
发明人： Joshua F. Krieger , Ram H. Paul , Zachary Berwick
IPC分类号： A61B17/32 , B21F45/00 , A61B17/00
摘要： Cutting devices useful for cutting objects or materials are described. Examples of cutting devices useful for creating avulsions in animals, such as human beings, are described. A cutting device includes an elongate main body having proximal and distal ends. A first portion of the main body has a cross-sectional shape that substantially lacks flat surfaces and a second portion of the main body has a cross-sectional shape having one, two or more flat surfaces. The distal end defines a hook having one or more sharpened edges disposed within the notch of the hook. Methods of making cutting devices are also described.

8. 发明授权

US10271970B2 Blood perfusion device 有权
公开(公告)号：US10271970B2
公开(公告)日：2019-04-30
申请号：US13761391
申请日：2013-02-07
申请人： Cook Medical Technologies LLC
发明人： Ram H. Paul , Richard A. Swift , Oliver Bach , Ralf Steiner , Angela R. Barnett , Keith R. Milner
IPC分类号： A61F2/82 , A61F2/915 , A61F2/07 , A61F2/848
摘要： A perfusion device and a delivery system for repair of a damaged portion of a body vessel. Perfusion device can include a tubular body that is self-expandable, having a proximal portion, a distal portion, and an intermediate portion. One or more series of barbs can be disposed circumferentially along the intermediate portion. Barbs are capable of penetrating into the tunica intima and tunica media of said vessel wall upon insertion of said device into said body vessel, and not into said tunica adventitia. A graft can be associated with the tubular body. Graft has a proximal end and a distal end, and preferably extends entirely along a luminal wall of the tubular body. Graft may also extend along an exterior surface of the tubular body at the proximal and distal portions. Delivery devices for the perfusion implant and methods of delivering the perfusion implant are also provided.

9. 发明申请

US20180028216A1 Cutting Devices and Methods 审中-公开
公开(公告)号：US20180028216A1
公开(公告)日：2018-02-01
申请号：US15727791
申请日：2017-10-09
申请人： Cook Medical Technologies LLC
发明人： Joshua F. Krieger , Ram H. Paul , Zachary Berwick
IPC分类号： A61B17/32 , B21F45/00 , A61B17/00
CPC分类号： A61B17/320016 , A61B17/32 , A61B2017/00526 , B21F45/008
摘要： Cutting devices useful for cutting objects or materials are described. Examples of cutting devices useful for creating avulsions in animals, such as human beings, are described. A cutting device includes an elongate main body having proximal and distal ends. A first portion of the main body has a cross-sectional shape that substantially lacks flat surfaces and a second portion of the main body has a cross-sectional shape having one, two or more flat surfaces. The distal end defines a hook having one or more sharpened edges disposed within the notch of the hook. Methods of making cutting devices are also described.

10. 发明申请

US20140324155A1 BLOOD PERFUSION DEVICE DELIVERY SYSTEM 有权
公开(公告)号：US20140324155A1
公开(公告)日：2014-10-30
申请号：US14324878
申请日：2014-07-07
申请人： Cook Medical Technologies LLC
发明人： Ram H. Paul
IPC分类号： A61F2/07 , A61F2/86
CPC分类号： A61F2/07 , A61B2017/1107 , A61B2017/1132 , A61F2/06 , A61F2/848 , A61F2/86 , A61F2/89 , A61F2/915 , A61F2002/075 , A61F2002/8483 , A61F2002/91558 , A61F2002/91575 , A61F2210/0076 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2220/0075 , A61F2250/0023 , A61F2250/0036 , A61F2250/0037
摘要： A delivery system deploys a prosthesis for open surgical repair of a body vessel. The system includes a sleeve to retain segments of a prosthesis in a compressed configuration and retraction members. The sleeve has outer segments associated with each end of the prosthesis. Retraction of the retraction members removes the outer segments of the sleeve from the prosthesis outer ends to allow for expansion of the outer ends of the prosthesis in an outside-in direction. The system can include a handle and an actuation member movably attached to the handle. The actuation member is coupled to the sleeve outer segments so that movement of the actuation member corresponds to removal of the sleeve. The system can include elements to retain the sleeve outer segments to the actuation member and to redirect the retraction members to a direction different from the axis of the prosthesis.
摘要翻译：输送系统部署用于身体血管的开放手术修复的假体。该系统包括用于将假体的段保持在压缩构造和缩回构件中的套筒。套筒具有与假体的每个端部相关联的外部段。缩回构件的缩回将套筒的外部段从假体外端移除，以允许假体的外端在外侧方向上的膨胀。该系统可以包括手柄和可移动地附接到手柄的致动构件。致动构件联接到套筒外部段，使得致动构件的运动对应于套筒的移除。该系统可以包括将套筒外部段保持在致动构件上的元件，并且将收缩构件重定向到与假体轴线不同的方向。

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