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1. 发明授权

US09997260B2 Retrieval of similar patient cases based on disease probability vectors 有权
公开(公告)号：US09997260B2
公开(公告)日：2018-06-12
申请号：US12810021
申请日：2008-12-08
申请人： Pradyumna Dutta , Colleen M. Ennett
发明人： Pradyumna Dutta , Colleen M. Ennett
IPC分类号： G06F17/30
CPC分类号： G16H50/70 , G06F19/00
摘要： A method of retrieving similar patient cases from a medical database includes matching a current patient case against a plurality of clinical profiles resulting in a set of matching clinical profiles. The method further includes determining a degree of membership of the current patient case in each clinical profile from the set of matching clinical profiles based upon a degree of match between the current patient case and the clinical profile. For at least one clinical profile from the set of matching clinical profiles, the method includes retrieving those similar patient cases from the medical database that have a substantially corresponding degree of membership as the current patient case.

2. 发明申请

US20120239435A1 AUTOMATED ANNOTATION OF CLINICAL DATA 审中-公开
标题翻译：自动临床数据统计
公开(公告)号：US20120239435A1
公开(公告)日：2012-09-20
申请号：US13512356
申请日：2010-11-17
申请人： Colleen M. Ennett , Pradyumna Dutta
发明人： Colleen M. Ennett , Pradyumna Dutta
IPC分类号： G06Q50/24
CPC分类号： G06F19/325 , G16H15/00
摘要： When annotating a patient's medical or clinical record, an automated annotation system compares aggregated patient data (e.g., historical vital sign data, lab results, patient admission/discharge/transfer information, etc.) and matches events and/or patterns therein to procedure profiles to determine whether a given procedure is required, in progress, or completed. If the probability of procedure necessity or occurrence is above a predetermined threshold, then system inserts an annotation into the clinical record to mitigate a need for a clinician to manually enter the annotation. Alarm parameters are adjusted to reflect a physiological response to the determined procedure, to reduce false alarm triggers. Additionally or alternatively, triggered advisories may be suppressed from the user interface for a time period during which conditions specified in the procedure profile exist, or for a specific period of time following the procedure. In another embodiment, triggered advisories that occur under the specific conditions identified in a procedure profile may be flagged in the patient's medical record with a notification that the suspected procedure is being performed.
摘要翻译：当注释患者的医疗或临床记录时，自动注释系统比较汇总的患者数据（例如历史生命体征数据，实验室结果，患者入院/放电/转移信息等）并将其中的事件和/或模式与其中的事件和/或模式进行比较以确定是否需要，正在进行或完成给定的过程。如果程序必要性或发生概率高于预定阈值，则系统将注释插入到临床记录中以减轻临床医生手动输入注释的需要。调整报警参数以反映对所确定过程的生理响应，以减少误报触发。附加地或替代地，在过程配置文件中指定的条件存在或在该过程之后的特定时间段内，可以从用户界面抑制触发的建议。在另一个实施例中，在过程简档中识别的特定条件下发生的触发咨询可以被标记在患者的医疗记录中，并且具有正在执行可疑过程的通知。

3. 发明申请

US20120123801A1 PET/CT BASED MONITORING SYSTEM SUPPORTED BY A CLINICAL GUIDELINE NAVIGATOR 审中-公开
标题翻译：基于PET / CT的监测系统由临床导向导管支持
公开(公告)号：US20120123801A1
公开(公告)日：2012-05-17
申请号：US13260533
申请日：2010-02-11
申请人： Roland Opfer , Lilla Boroczky , Ingwer Curt Carlsen , Pradyumna Dutta , Steffen Renisch , Joerg Sabczynski , Paola Karina Tulipano
发明人： Roland Opfer , Lilla Boroczky , Ingwer Curt Carlsen , Pradyumna Dutta , Steffen Renisch , Joerg Sabczynski , Paola Karina Tulipano
IPC分类号： G06Q50/24
CPC分类号： G16H10/60 , A61B6/037 , A61B6/508 , G06F19/00 , G06F19/321 , G06Q50/24
摘要： An oncology monitoring system comprises: an image analysis module (42, 44) configured to perform an oncological monitoring operation based on images of a subject, for example acquired by positron emission tomography (PET) and computed tomography (CT); and a clinical guideline support module (10). The clinical guideline support module is configured to: display a graphical flow diagram (GFD) of a clinical therapy protocol for treating the subject comprising graphical blocks (B0, B1 B2, B3, B4, B5, B21, B211, B22, B221, B222, B223, B23, B231, B232) representing therapeutic or monitoring operations of the clinical therapy protocol including at least one monitoring operation performed by the image analysis module; annotate a graphical block of the graphical flow diagram with subject-specific information pertaining to a therapeutic or monitoring operation represented by the graphical block; and display an annotation (POP) of a graphical block (B211) responsive to selection of the graphical block by a user.
摘要翻译：肿瘤监测系统包括：图像分析模块（42,44），其被配置为基于例如通过正电子发射断层摄影（PET）和计算机断层摄影（CT）获取的对象的图像执行肿瘤监测操作; 和临床指南支持模块（10）。临床指南支持模块被配置为：显示用于治疗受试者的临床治疗方案的图形流程图（GFD），包括图形块（B0，B1B2，B3，B4，B5，B21，B211，B22，B221，B222 ，B223，B23，B231，B232），其代表包括图像分析模块执行的至少一个监视操作的临床治疗方案的治疗或监视操作; 注释图形流程图的图形块，其具有与由图形块表示的治疗或监视操作有关的主题特定信息; 以及响应于用户对所述图形块的选择来显示图形块（B211）的注释（POP）。

4. 发明申请

US20100312798A1 RETRIEVAL OF SIMILAR PATIENT CASES BASED ON DISEASE PROBABILITY VECTORS 有权
标题翻译：基于疾病概率向量的类似病例的检索
公开(公告)号：US20100312798A1
公开(公告)日：2010-12-09
申请号：US12810021
申请日：2008-12-08
申请人： Pradyumna Dutta , Colleen Ennett
发明人： Pradyumna Dutta , Colleen Ennett
IPC分类号： G06F17/30
CPC分类号： G16H50/70 , G06F19/00
摘要： A method of retrieving similar patient cases from a medical database includes matching a current patient case against a plurality of clinical profiles resulting in a set of matching clinical profiles. The method further includes determining a degree of membership of the current patient case in each clinical profile from the set of matching clinical profiles based upon a degree of match between the current patient case and the clinical profile. For at least one clinical profile from the set of matching clinical profiles, the method includes retrieving those similar patient cases from the medical database that have a substantially corresponding degree of membership as the current patient case.
摘要翻译：从医学数据库中检索类似的病例的方法包括将当前患者病例与多个临床特征进行匹配，从而产生一组匹配的临床特征。该方法还包括基于当前患者病例和临床特征之间的匹配程度，从所述一组匹配临床特征中确定每个临床剖面中当前患者病例的隶属程度。对于来自所述一组匹配临床特征的至少一个临床特征，所述方法包括从所述医疗数据库检索具有与当前患者病例基本上相应程度的隶属度的那些相似的患者病例。

5. 发明申请

US20100324938A1 METHOD AND APPARATUS FOR IDENTIFYING RELATIONSHIPS IN DATA BASED ON TIME-DEPENDENT RELATIONSHIPS 审中-公开
标题翻译：基于时间依赖关系识别数据关系的方法和装置
公开(公告)号：US20100324938A1
公开(公告)日：2010-12-23
申请号：US12808371
申请日：2008-12-10
申请人： Colleen Ennett , Pradyumna Dutta , N. Stephen Ober
发明人： Colleen Ennett , Pradyumna Dutta , N. Stephen Ober
IPC分类号： G06Q50/00 , G06F17/30
CPC分类号： G06Q50/24 , G06F19/3481 , G16H10/60
摘要： A decision support apparatus (100) includes a subject record database (102), a temporally dependent relationship identifier (104), an event predictor (130), a coded subject record database (106), a decision support system processor (108), and a user interface (110). The temporally dependent relationship identifier processes the data in the subject record database (102) to identify temporally dependent relationships in the data. Information indicative of the identified relationships is processed by the processor (108) and presented to a user via the user interface (110).
摘要翻译：决策支持设备（100）包括主题记录数据库（102），时间上依赖关系标识符（104），事件预测器（130），编码对象记录数据库（106），决策支持系统处理器（108）和用户界面（110）。时间依赖关系标识符处理主体记录数据库（102）中的数据以识别数据中的时间上依赖的关系。指示所识别的关系的信息由处理器（108）处理并经由用户界面（110）呈现给用户。

6. 发明授权

US10311971B2 PET/CT based monitoring system supported by a clinical guideline navigator 有权
公开(公告)号：US10311971B2
公开(公告)日：2019-06-04
申请号：US13260533
申请日：2010-02-11
申请人： Roland Johannes Opfer , Lilla Boroczky , Ingwer Curt Carlsen , Pradyumna Dutta , Steffen Renisch , Joerg Sabczynski , Paola Karina Tulipano
发明人： Roland Johannes Opfer , Lilla Boroczky , Ingwer Curt Carlsen , Pradyumna Dutta , Steffen Renisch , Joerg Sabczynski , Paola Karina Tulipano
IPC分类号： G16H30/20 , G16H20/40 , A61B6/03 , G06F19/00 , G06Q50/24 , G16H10/60 , A61B6/00
摘要： An oncology monitoring system comprises: an image analysis module (42, 44) configured to perform an oncological monitoring operation based on images of a subject, for example acquired by positron emission tomography (PET) and computed tomography (CT); and a clinical guideline support module (10). The clinical guideline support module is configured to: display a graphical flow diagram (GFD) of a clinical therapy protocol for treating the subject comprising graphical blocks (B0, B1, B2, B3, B4, B5, B21, B211, B22, B221, B222, B223, B23, B231, B232) representing therapeutic or monitoring operations of the clinical therapy protocol including at least one monitoring operation performed by the image analysis module; annotate a graphical block of the graphical flow diagram with subject-specific information pertaining to a therapeutic or monitoring operation represented by the graphical block; and display an annotation (POP) of a graphical block (B211) responsive to selection of the graphical block by a user.

7. 发明授权

US08388348B2 Disease treatment simulation 有权
标题翻译：疾病治疗模拟
公开(公告)号：US08388348B2
公开(公告)日：2013-03-05
申请号：US11607435
申请日：2006-12-01
申请人： George R. Biltz , Pradyumna Dutta , Paul E. Johnson , Patrick J. O'Connor , William A. Rush , JoAnn M. Sperl-Hillen
发明人： George R. Biltz , Pradyumna Dutta , Paul E. Johnson , Patrick J. O'Connor , William A. Rush , JoAnn M. Sperl-Hillen
IPC分类号： G09B23/28
CPC分类号： G09B7/00 , G06G7/48 , G09B19/00 , G09B23/28
摘要： There are provided a method, system and medium having instructions embedded to determine an attribute of a simulated patient's state resulting from a patient-physician encounter. The method includes receiving a current treatment move and an initial value of the attribute; calculating a maximal expected incremental effect value of the current treatment move over a previous treatment move on the attribute; attenuating the maximal expected incremental effect value based on amount of time between the previous treatment move and the current treatment move; summing the attenuated maximal expected incremental effect value with the initial value to generate an updated attribute of the simulated patient's state; and generating a patient-physician encounter that includes the updated attribute.
摘要翻译：提供了一种方法，系统和介质，其具有嵌入的指令以确定由患者 - 医师相遇产生的模拟患者状态的属性。该方法包括接收当前处理动作和属性的初始值; 计算当前治疗移动的最大预期增量效应值; 根据以前的处理动作和当前处理动作之间的时间量来衰减最大预期增量效应值; 将衰减的最大预期增量效应值与初始值相加以生成模拟患者状态的更新属性; 以及产生包括更新的属性的患者 - 医生遭遇。

8. 发明申请

US20070148625A1 Disease treatment simulation 有权
标题翻译：疾病治疗模拟
公开(公告)号：US20070148625A1
公开(公告)日：2007-06-28
申请号：US11607435
申请日：2006-12-01
申请人： George Biltz , Pradyumna Dutta , Paul Johnson , Patrick O'Connor , William Rush , JoAnn Sperl-Hillen
发明人： George Biltz , Pradyumna Dutta , Paul Johnson , Patrick O'Connor , William Rush , JoAnn Sperl-Hillen
IPC分类号： G09B23/28 , G06G7/48
CPC分类号： G09B7/00 , G06G7/48 , G09B19/00 , G09B23/28
摘要： There are provided a method, system and medium having instructions embedded to determine an attribute of a simulated patient's state resulting from a patient-physician encounter. The method includes receiving a current treatment move and an initial value of the attribute; calculating a maximal expected incremental effect value of the current treatment move over a previous treatment move on the attribute; attenuating the maximal expected incremental effect value based on amount of time between the previous treatment move and the current treatment move; summing the attenuated maximal expected incremental effect value with the initial value to generate an updated attribute of the simulated patient's state; and generating a patient-physician encounter that includes the updated attribute.
摘要翻译：提供了一种方法，系统和介质，其具有嵌入的指令以确定由患者 - 医师相遇产生的模拟患者状态的属性。该方法包括接收当前处理移动和属性的初始值; 计算当前治疗移动的最大预期增量效应值; 根据以前的处理动作和当前处理动作之间的时间量，衰减最大预期增量效应值; 将衰减的最大预期增量效应值与初始值相加以生成模拟患者状态的更新属性; 以及产生包括更新的属性的患者 - 医生遭遇。

9. 发明申请

US20130275161A1 System and Method for Providing Medical Caregiver and Equipment Management Patient Care 审中-公开
标题翻译：提供医疗照护者和设备管理患者护理的系统和方法
公开(公告)号：US20130275161A1
公开(公告)日：2013-10-17
申请号：US13995504
申请日：2011-12-05
申请人： Pradyumna Dutta , Cornelis Conradus Adrianus Maria Van Zon , Steffen Clarence Pauws , William Palmer Lord , Juergen Te Vrugt , Alphonsus Anthonius Jozef De Lange
发明人： Pradyumna Dutta , Cornelis Conradus Adrianus Maria Van Zon , Steffen Clarence Pauws , William Palmer Lord , Juergen Te Vrugt , Alphonsus Anthonius Jozef De Lange
IPC分类号： G06F19/00
CPC分类号： G06F19/324 , G06Q10/06 , G06Q50/22
摘要： An update message from a first group of one or more clinical devices (802) is received over a communications network (504). The update message includes patient data and identifies a computer interpretable guideline (CIG) instance corresponding to a patient of the patient data. The CIG instance is updated (804) using the patient data and one or more CIG recommendations are determined (806) based on the updated CIG instance. The CIG recommendations are communicated (808) to a second group of one or more clinical devices over the communications network (504). Also disclosed, a narrative guideline is received from a guideline publisher and/or business entity (102) over a communications network (104). The narrative guideline is transformed to a computer represented guideline (CRG) abstractly representing the narrative guideline on the basis of usage. The translation includes linking text fragments in the narrative guideline to instantiated language constructs.
摘要翻译：通过通信网络（504）接收来自一个或多个临床装置（802）的第一组的更新消息。所述更新消息包括患者数据并且识别对应于患者数据的患者的计算机可解释指导（CIG）实例。使用患者数据更新（804）CIG实例，并且基于更新的CIG实例确定一个或多个CIG建议（806）。通过通信网络（504）将CIG建议（808）传送到第二组一个或多个临床设备。还公开了，通过通信网络（104）从指南发布者和/或业务实体（102）接收叙述指南。叙述性指南被转换为以使用为基础抽象代表叙事方针的计算机代表指南（CRG）。翻译包括将叙述指南中的文本片段与实例化的语言结构相链接。

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