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1. 发明申请

US20100184809A1 Heterocyclic FXR Binding Compounds 审中-公开
标题翻译：杂环FXR结合化合物
公开(公告)号：US20100184809A1
公开(公告)日：2010-07-22
申请号：US12376482
申请日：2007-08-29
申请人： Claus Kremoser , Ulrich Deuschle , Ulrich Abel , Andreas Schulz
发明人： Claus Kremoser , Ulrich Deuschle , Ulrich Abel , Andreas Schulz
IPC分类号： A61K31/4439 , C07D413/12 , A61P3/10 , A61P1/16 , A61P3/06 , A61P9/10 , A61P13/12 , A61P25/02 , A61P7/02 , A61P31/06 , A61P31/08 , A61P33/02 , A61P13/08 , A61P35/00
CPC分类号： C07D413/12 , C07D401/06 , C07D401/12 , C07D413/14
摘要： The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists or partial agonists of the NR1H4 receptor (FXR). The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds, and to a process for the synthesis of said compounds.
摘要翻译：本发明涉及结合NR1H4受体（FXR）并作为NR1H4受体（FXR）的激动剂或部分激动剂的化合物。本发明还涉及该化合物在制备用于通过所述化合物与所述核受体结合来治疗疾病和/或病症的药物的用途，以及合成所述化合物的方法中的用途。

2. 发明授权

US08193192B2 Heterocyclic FXR binding compounds 有权
标题翻译：杂环FXR结合化合物
公开(公告)号：US08193192B2
公开(公告)日：2012-06-05
申请号：US12377307
申请日：2007-08-29
申请人： Claus Kremoser , Ulrich Deuschle , Ulrich Abel , Andreas Schulz
发明人： Claus Kremoser , Ulrich Deuschle , Ulrich Abel , Andreas Schulz
IPC分类号： A61K31/50 , A61K31/501 , A61K31/497 , C07D413/00 , C07D401/00 , C07D403/00 , C07D405/00 , C07D409/00
CPC分类号： C07D413/12
摘要： The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists or partial agonists of the NR1H4 receptor (FXR). The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds, and to a process for the synthesis of said compounds.
摘要翻译：本发明涉及结合NR1H4受体（FXR）并作为NR1H4受体（FXR）的激动剂或部分激动剂的化合物。本发明还涉及该化合物在制备用于通过所述化合物与所述核受体结合来治疗疾病和/或病症的药物的用途，以及合成所述化合物的方法中的用途。

3. 发明申请

US20100210660A1 Heterocyclic FXR Binding Compounds 有权
标题翻译：杂环FXR结合化合物
公开(公告)号：US20100210660A1
公开(公告)日：2010-08-19
申请号：US12377307
申请日：2007-08-29
申请人： Claus Kremoser , Ulrich Deuschle , Ulrich Abel , Andreas Schulz
发明人： Claus Kremoser , Ulrich Deuschle , Ulrich Abel , Andreas Schulz
IPC分类号： A61K31/4439 , C07D413/12 , A61K31/501 , A61P1/16 , A61P29/00 , A61P3/06 , A61P3/10 , A61P9/00 , A61P35/00
CPC分类号： C07D413/12
摘要： The present invention relates to compounds which bind to the NRI H4 receptor (FXR) and act as agonists or partial agonists of the NR1 H4 receptor (FXR). The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds, and to a process for the synthesis of said compounds.
摘要翻译：本发明涉及结合NRI H4受体（FXR）并作为NR1H4受体（FXR）的激动剂或部分激动剂的化合物。本发明还涉及该化合物在制备用于通过所述化合物与所述核受体结合来治疗疾病和/或病症的药物的用途，以及合成所述化合物的方法中的用途。

4. 发明授权

US09186662B2 Positioning device and method with rotary indexing table for monolith-based automobile and chemical catalysts 有权
标题翻译：用于整体式汽车和化学催化剂的旋转分度台的定位装置和方法
公开(公告)号：US09186662B2
公开(公告)日：2015-11-17
申请号：US13057861
申请日：2009-07-31
申请人： Kai Schmitz , Andreas Schulz
发明人： Kai Schmitz , Andreas Schulz
IPC分类号： B01J37/02 , B05C3/09 , B05C13/02 , B05C13/00 , B05D7/22
CPC分类号： B01J37/0215 , B01J37/02 , B05C3/09 , B05C13/00 , B05C13/02 , B05C13/025 , B05D7/22
摘要： The invention relates to a processing and positioning device for processing catalyst support bodies. The device comprises a rotary indexing table, which comprises a turntable, which is rotatable about a longitudinal axis running in the axial direction of the turntable, and at least one loading platform, which comprises a holding device and is set up for releasably holding the catalyst support body on an outer surface of the catalyst support body. The at least one loading platform is connected to the turntable, whereby the loading platform is taken along by the turntable when a rotation of the turntable takes place about its longitudinal axis. The holding device is arranged in relation to the longitudinal axis of the turntable with a radial distance away from the longitudinal axis. Also provided is at least one processing position, which is fixed with respect to the turntable and is away from the longitudinal axis in a radial direction by a distance. The distance is provided in relation to the radial distance such that the loading platform can be arranged at the processing position. The invention also relates to a method for positioning catalyst support bodies which, by means of a circular movement, arranges the support bodies at positions that are in series according to the positioning along a circular line.
摘要翻译：本发明涉及一种用于处理催化剂载体的加工定位装置。该装置包括旋转分度台，该转台包括转盘，该转盘可围绕在转台的轴向方向上延伸的纵向轴线旋转;以及至少一个装载平台，其包括保持装置，并设置成可释放地保持催化剂支撑体在催化剂支撑体的外表面上。所述至少一个装载平台连接到所述转盘，由此当所述转台的旋转围绕其纵向轴线发生时，所述装载平台被所述转盘带走。保持装置相对于转盘的纵向轴线布置成离开纵向轴线的径向距离。还提供了至少一个处理位置，其相对于转台固定，并且在径向方向上远离纵轴一定距离。相对于径向距离设置距离，使得装载平台可以布置在处理位置。本发明还涉及一种用于定位催化剂支撑体的方法，其通过圆周运动将支撑体布置成根据沿着圆形线的定位而串联的位置。

5. 发明授权

US08266789B2 Device for the production of cable harnesses 有权
标题翻译：用于生产电缆线束的装置
公开(公告)号：US08266789B2
公开(公告)日：2012-09-18
申请号：US12952422
申请日：2010-11-23
申请人： Ray Peter Cardue , Sebastian Gorecki , Andreas Schulz , Michael Seikel
发明人： Ray Peter Cardue , Sebastian Gorecki , Andreas Schulz , Michael Seikel
IPC分类号： H01B13/012
CPC分类号： H01B13/01227 , Y10T29/532 , Y10T29/53243 , Y10T29/53265
摘要： There is disclosed a device for a production of cable harnesses, said device having a stand, a rotor, at least two rotor arms and at least two mounting boards, said rotor rotatably mounted on said stand and said rotor having said at least two rotor arms on which said at least two mounting boards are mounted, wherein each mounting board of said at least two mounting boards is configured to allow producing at least one cable harness. In a preferred embodiment each mounting board of said at least two mounting boards is mounted on two rotor arms of said at least two rotor arms in a vertically adjustable manner, and said rotor has a rotor post which extends upward from said stand and to which said at least two rotor arms are mounted. In a further preferred embodiment at least one electrical stand contact is mounted to said stand and is configured to be connected to an electrical test device, and an electrical mating contact is associated with each mounting board and is adapted to be connected to a cable harness which is arranged on said mounting board, wherein said mating contact of each mounting board comes into electrical contact with said stand contact in a specific rotation position of said rotor, in order to connect said cable harness to said test device.
摘要翻译：公开了一种用于生产电缆线束的装置，所述装置具有支架，转子，至少两个转子臂和至少两个安装板，所述转子可旋转地安装在所述支架上，所述转子具有所述至少两个转子臂其上安装有至少两个安装板，其中所述至少两个安装板的每个安装板被配置成允许产生至少一个电缆线束。在优选实施例中，所述至少两个安装板的每个安装板以垂直可调的方式安装在所述至少两个转子臂的两个转子臂上，并且所述转子具有从所述支架向上延伸的转子柱，至少安装两个转子臂。在进一步的优选实施例中，至少一个电架接触件被安装到所述支架上，并且被配置为连接到电测试装置，并且电配合触点与每个安装板相关联并且适于连接到电缆线束，布置在所述安装板上，其中每个安装板的所述配合触点在所述转子的特定旋转位置与所述支架触点电接触，以将所述电缆线束连接到所述测试装置。

6. 发明申请

US20070135289A1 Separator having a centrifugal drum and a piston slide 有权
标题翻译：分离器具有离心鼓和活塞滑块
公开(公告)号：US20070135289A1
公开(公告)日：2007-06-14
申请号：US10581894
申请日：2005-09-21
申请人： Wilfried Mackel , Andreas Schulz
发明人： Wilfried Mackel , Andreas Schulz
IPC分类号： B04B1/14
CPC分类号： B04B1/14 , B04B11/04
摘要： A separator having a rotatable drum (2) with a vertical axis of rotation (M), in which preferably a disk stack (7) is arranged, having a piston slide (13) for opening and closing solids discharge openings (14) in the drum (2), in the open condition of the piston slide (13), a radial gap (19) being formed between the drum, particularly between a drum top part (15), and the piston slide (13), is characterized in that at least one annular chamber (22) is constructed on both sides of the gap (19) radially in front of the solids discharge openings in the outer circumference area of the piston slide (13) and the drum, particularly in the top part (15) of the drum.
摘要翻译：一种具有垂直旋转轴线（M）的可旋转滚筒（2）的分离器，其中优选地布置有盘叠（7），其具有用于打开和关闭固体排出口（14）的活塞滑块（13）鼓（2）在活塞滑块（13）的打开状态下，形成在滚筒之间，特别是鼓顶部分（15）和活塞滑块（13）之间的径向间隙（19）的特征在于至少一个环形室（22）在活塞滑动件（13）和滚筒（特别是顶部）的外圆周区域的固体排放口的前方径向地构造在间隙（19）的两侧上 15）的鼓。

7. 发明授权

US06591135B2 Portable patient monitor with defibrillator/pacemaker interface and battery power management 失效
标题翻译：带除颤器/起搏器接口和电池电源管理的便携式患者监护仪
公开(公告)号：US06591135B2
公开(公告)日：2003-07-08
申请号：US09835459
申请日：2001-04-16
申请人： Michael J. Palmer , James M. Gray , David L. Schieble , Alan E. Clapp , Brian Bayer , Wilfried Loehning , Andreas Schulz , Horst Schlosser
发明人： Michael J. Palmer , James M. Gray , David L. Schieble , Alan E. Clapp , Brian Bayer , Wilfried Loehning , Andreas Schulz , Horst Schlosser
IPC分类号： A61N118
CPC分类号： A61N1/37 , A61B5/04 , A61N1/378 , A61N1/39 , A61N1/3975
摘要： A method and apparatus are provided for distributing power within a cardiac treatment and monitoring system which includes a defibrillator releasably coupled to a patient monitoring unit. The method includes the steps of determining a battery reserve capacity within the patient monitoring unit and distributing power from the patient monitoring system to a defibrillator when the determined battery reserve capacity exceeds a threshold value.
摘要翻译：提供了一种用于在心脏治疗和监测系统内分配功率的方法和装置，其包括可释放地联接到患者监测单元的除颤器。该方法包括以下步骤：当所确定的电池储备容量超过阈值时，确定患者监测单元内的电池储备容量并将电力从患者监测系统分配到除颤器。

8. 发明授权

US06180222B2 Gold-containing nanoporous aluminum oxide membranes a process for their production and their use 失效
标题翻译：含金的纳米孔氧化铝膜是其生产和使用的过程
公开(公告)号：US06180222B2
公开(公告)日：2001-01-30
申请号：US09133804
申请日：1998-08-13
申请人： Andreas Schulz , G{umlaut over (u)}nter Schmid , Gabor Louis Hornyak , Thomas Sawitowski
发明人： Andreas Schulz , G{umlaut over (u)}nter Schmid , Gabor Louis Hornyak , Thomas Sawitowski
IPC分类号： B05D118
CPC分类号： C04B41/009 , C03C17/008 , C04B41/4501 , C04B41/4554 , C04B41/49 , C04B41/81 , C04B41/84 , C23C18/08 , C25D11/18 , Y10T428/24997 , Y10T428/249986 , Y10T428/268 , C04B41/4582 , C04B41/5031 , C04B2103/0086 , C04B41/5116 , C04B41/4564 , C04B33/00 , C04B35/10 , C04B38/0025
摘要： Red decorations on substrates which can undergo decorative baking, such as glass, porcelain, ceramic and metal, can be produced using nanoporous aluminium oxide membranes according to the invention, the nanopores of which contain ligand-stabilized gold clusters. The membrane is applied to the substrate followed by baking, resulting in formation of the red color. Alternatively, the membrane can be converted into a red membrane by thermolysis, after which the membrane is employed for production of the decoration. The membranes according to the invention can be obtained by bringing a nanoporous Al2O3 membrane into contact with a solution of a ligand-stabilized gold cluster, in particular one of the formula Au55L12X6, wherein L is a phosphane ligand and X is an anion.
摘要翻译：可以使用根据本发明的纳米多孔氧化铝膜（其纳米孔含有配体稳定的金簇）来制造可以进行装饰烘烤的基底上的红色装饰物，例如玻璃，瓷器，陶瓷和金属。将膜施加到基底上，随后烘烤，形成红色。或者，可以通过热分解将膜转化成红色膜，之后将膜用于制造装饰。根据本发明的膜可以通过使纳米多孔Al 2 O 3膜与配位体稳定的金簇，特别是式为Au55L12X6的溶液接触，其中L是磷烷配体，X是阴离子。

9. 发明授权

US5705664A Mononoble metal dithiolates, preparations containing them and their use 失效
标题翻译：单体金属二硫醇盐，含有它们的制剂及其用途
公开(公告)号：US5705664A
公开(公告)日：1998-01-06
申请号：US390480
申请日：1995-02-17
申请人： Andreas Schulz , Marco Hofler
发明人： Andreas Schulz , Marco Hofler
IPC分类号： C03C17/10 , C04B41/45 , C04B41/51 , C04B41/81 , C04B41/88 , C07C323/12 , C07C323/52 , C07C323/60 , C07C323/66 , C07F1/10 , C07F1/12 , C07F15/00 , H05K1/09 , C07F1/08 , B05D3/00 , B05D5/00 , B41M3/12
CPC分类号： C04B41/009 , C03C17/10 , C04B41/4554 , C04B41/5105 , C04B41/81 , C04B41/88 , C07C323/12 , C07C323/52 , C07C323/60 , C07C323/66 , H05K1/092
摘要： The invention relates to mononoble metal dithiolates, more particularly water-soluble monogold(I) dithiolates, to their production and to their use for the production of noblemetal-containing decorations on firing-resistant substrates. The mononoble metal dithiolates represent a new class of water-soluble thiolates for use in organic-aqueous and essentially purely aqueous noble metal preparations for decoration purposes. The mononoble metal dithiolates correspond to the following formula: ##STR1## in which Em=Au(I), Ag(I), an equivalent of Pd(II), Pt(II) or Rh(III), Q=a tetravalent organic radical containing 2 to 10 carbon atoms, Y=a hydrophilic group from the series comprising --COOH, --COO.sup.- cat.sup.+ or --COO--(CHR.sup.1 --CHR.sup.2 --O).sub.m R.sup.3 Z=Y or H or a group from the series comprising --OR', --SR', --SO.sub.3 R', --NR'.sub.2, --NR.sub.3.sup.+ X.sup.-.
摘要翻译：本发明涉及单一金属二硫醇盐，更特别是水溶性单钼酸（I）二硫醇盐，用于其生产和用于在耐燃基材上生产含贵金属的装饰品。单一金属二硫醇盐代表一类新型的水溶性硫醇盐，用于装饰用的有机水性和基本上纯的含水贵金属制剂。单体金属二硫醇盐对应于下式：其中Em = Au（I），Ag（I），当量Pd（II），Pt（II）或Rh（III），Q = 含有2至10个碳原子的四价有机基团，Y =包含-COOH，-COO-cat +或-COO-（CHR 1 -CHR 2 -O）m R 3 Z = Y或H的系列的亲水基团或来自该系列的基团包括-OR'，-SR'，-SO 3 R'，-NR'2，-NR 3 + X - 。

10. 发明授权

US08758209B2 Separator having a lubrication system for a short spindle drive 失效
标题翻译：具有用于短轴驱动的润滑系统的分离器
公开(公告)号：US08758209B2
公开(公告)日：2014-06-24
申请号：US12747449
申请日：2008-11-27
申请人： Wilfried Mackel , Thomas Bathelt , Andreas Penkl , Andreas Schulz , Marie-Theres Sedler
发明人： Wilfried Mackel , Thomas Bathelt , Andreas Penkl , Andreas Schulz , Marie-Theres Sedler
IPC分类号： B04B9/04 , B04B9/12 , B04B9/14 , B04B15/00
CPC分类号： B04B9/08 , B04B9/04 , B04B9/12 , F16C19/54 , F16C33/6659
摘要： A separator including a rotatable centrifugal drum having a vertical axis of rotation and an inflow line for a material to be processed by the separator. Also included is a drive spindle for the drum rotatably mounted via a mounting to a housing supported elastically on a machine stand section. A drive device includes an electric drive motor having a stator and a rotor which is aligned with the drive spindle. A lubricant system is configured to lubricate the mounting and the lubricant system includes a lubricant circuit to convey lubricant and has a lubricant collecting container.
摘要翻译：一种分离器，包括具有垂直旋转轴线的可旋转离心鼓和用于由分离器处理的材料的流入管线。还包括用于滚筒的驱动主轴，其通过安装件可旋转地安装到弹性地支撑在机架支架部分上的壳体。驱动装置包括具有定子和与驱动主轴对准的转子的电动驱动马达。润滑剂系统被配置为润滑安装件，并且润滑剂系统包括用于输送润滑剂的润滑剂回路并且具有润滑剂收集容器。

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