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1. 发明授权

US08734513B2 Artificial retinal system and retinal implant chip thereof 有权
标题翻译：人造视网膜系统及其视网膜植入物芯片
公开(公告)号：US08734513B2
公开(公告)日：2014-05-27
申请号：US13586063
申请日：2012-08-15
申请人： Chun-Yu Wu , Po-Kang Lin , Chuan-Chin Chiao , Jui-Wen Pan , Wen-Chia Yang
发明人： Chun-Yu Wu , Po-Kang Lin , Chuan-Chin Chiao , Jui-Wen Pan , Wen-Chia Yang
IPC分类号： A61F2/16
CPC分类号： A61N1/36 , A61N1/0543 , A61N1/36046
摘要： An artificial retinal system includes an external optical device having an image generator and a background light generator, and a retinal implant chip having a solar cell and a stimulus generator. The stimulus generator is disposed to receive a target image projected by the image generator and a background light provided by the background light generator, and receives the electrical power from the solar cell. The stimulus generator includes an image sensing stimulator operable to convert the target image into electrical stimuli, and a contrast enhancer for reducing effect of the background light on the electrical stimuli.
摘要翻译：人造视网膜系统包括具有图像发生器和背景光发生器的外部光学装置，以及具有太阳能电池和刺激发生器的视网膜植入芯片。激励发生器被设置为接收由图像发生器投影的目标图像和由背景光发生器提供的背景光，并且从太阳能电池接收电力。刺激发生器包括可操作以将目标图像转换成电刺激的图像感测刺激器，以及用于减少背景光对电刺激的影响的对比度增强器。

2. 发明授权

US07622702B2 Power controlling apparatus applied to biochip and operating method thereof 有权
标题翻译：应用于生物芯片的功率控制装置及其操作方法
公开(公告)号：US07622702B2
公开(公告)日：2009-11-24
申请号：US12129237
申请日：2008-05-29
申请人： Chung-Yu Wu , Po-Kang Lin , Li-Ju Lin , Wen-Chia Yang , Chen Wan
发明人： Chung-Yu Wu , Po-Kang Lin , Li-Ju Lin , Wen-Chia Yang , Chen Wan
IPC分类号： A61F2/14 , H03H11/16
CPC分类号： A61F9/08
摘要： The invention discloses a power controlling apparatus for a biochip including M regions. Each region includes a plurality of cells respectively. The power controlling apparatus includes a pulse generating module, a combinational circuit, and M controlling modules. The pulse generating module generates a pulse. The combinational circuit receives the pulse and generates M controlling signals. Each controlling signal has a predetermined phase which is different from the phase of the other controlling signal. The M controlling modules are electrically connected to the combinational circuit. Each of the M controlling signals corresponds to and activates one of the M controlling modules to selectively power on one corresponding region of the M regions. The cells in the corresponding region which is powered have an action potential refractory time that is longer than the power-on interval of the corresponding region.
摘要翻译：本发明公开了一种用于包括M个区域的生物芯片的功率控制装置。每个区域分别包括多个单元。功率控制装置包括脉冲发生模块，组合电路和M个控制模块。脉冲发生模块产生脉冲。组合电路接收脉冲并产生M个控制信号。每个控制信号具有与另一个控制信号的相位不同的预定相位。 M个控制模块电连接到组合电路。 M个控制信号中的每一个对应于并激活M个控制模块中的一个，以选择性地对M个区域的一个对应区域供电。被供电的相应区域中的电池具有比对应区域的通电间隔更长的动作电位难度时间。

3. 发明授权

US08177714B2 Surgery assisting instrument for retinal surgery 有权
标题翻译：手术辅助手术视网膜手术
公开(公告)号：US08177714B2
公开(公告)日：2012-05-15
申请号：US11959463
申请日：2007-12-19
申请人： Po-Kang Lin
发明人： Po-Kang Lin
IPC分类号： A61B1/32
CPC分类号： A61F9/00727
摘要： A surgery assisting instrument for retinal surgery includes a cylinder and a strip connected with each other. The cylinder and the strip are made of a soft and biocompatible material. The cylinder is preferably connected with the strip at a side surface and close to an edge of the strip. The surgery assisting instrument is placed in a fornix around an eye at a position according to a retinal tear. The cylinder is pressed against the eye and the strip is pressed against the eyelid. Thus the retina is forced toward the back wall of the eye.
摘要翻译：用于视网膜手术的手术辅助器械包括彼此连接的圆筒和条带。圆筒和条带由柔软且生物相容的材料制成。圆柱体优选地与条带在侧表面处并且靠近条带的边缘连接。根据视网膜撕裂，将手术辅助器械置于围绕眼睛的穹窿内。将圆筒压在眼睛上，并将条带压在眼睑上。因此，视网膜被迫朝向眼睛的后壁。

4. 发明授权

US10532210B2 Device for stimulating optic nerve fibers 有权
公开(公告)号：US10532210B2
公开(公告)日：2020-01-14
申请号：US15590076
申请日：2017-05-09
申请人： Po-Kang Lin
发明人： Po-Kang Lin
IPC分类号： A61N1/36 , A61N1/05
摘要： The present invention provides a device for stimulating optic nerve fibers. The device includes a plurality of columnar electrodes and a power source. The columnar electrodes are disposed respectively in parallel to a length direction of an optic nerve of a human eye and are also disposed around the optic nerve along a circumferential direction thereof. Each of the columnar electrodes has a length. The power source is configured to supply power to the columnar electrodes. A human retina consists of the optic nerve fibers, which are connected to the optic nerve and a macular area of the human eye in a form of layers. The columnar electrodes are configured to stimulate the optic nerve fibers around the optic nerve with electrical stimulation.

5. 发明授权

US10272245B2 Neural sensing method for retina application and device thereof 有权
公开(公告)号：US10272245B2
公开(公告)日：2019-04-30
申请号：US15874898
申请日：2018-01-19
申请人： Po-Kang Lin
发明人： Po-Kang Lin
IPC分类号： A61N1/05 , A61N1/36
摘要： A neural sensing method includes the steps of: configuring an array of sensing units on a retina of a user, each of the sensing units detecting a signal and generating a sensed signal; generating a control signal by a control signal generator and transmitting the control signal to at least one electrode installed in a periphery of each of the sensing units; isolating each of the sensed signals by the control signal, thereby suppressing the mutual interference between the sensed signals by the control signal; and generating and outputting a processed signal to at least one neuron via a signal processing module with reference to the control signal and the sensed signals. The control signal has a signal strength lower than the sensing threshold of the at least one neuron.

6. 发明授权

US10023004B2 Deformable tire 有权
公开(公告)号：US10023004B2
公开(公告)日：2018-07-17
申请号：US15215606
申请日：2016-07-21
申请人： Po-Kang Lin
发明人： Po-Kang Lin
IPC分类号： B60B1/06 , B60B1/00
摘要： The present invention provides a deformable tire including a plurality of spokes. A first end of each of the spokes is connected to a core structure, and a second end of each of the spokes is connected to a tire body. A first length is provided between each of the tire bodies and the core structure connected by each of the spokes, and the spokes are elastic. The core structure is configured to fix and support the plurality of spokes, and each of the first lengths is dynamically adjusted by the elasticity of the spokes.

7. 发明申请

US20170211110A1 PHOTOSYNTHETIC DEVICE WITH MICROFLUID CHAMBER FOR CAUSING PHOTOSYNTHESIS THEREIN AND METHOD THEREOF 审中-公开
公开(公告)号：US20170211110A1
公开(公告)日：2017-07-27
申请号：US15482853
申请日：2017-04-10
申请人： Po-Kang Lin
发明人： Po-Kang Lin
IPC分类号： C12P19/02 , C12M1/00 , C12M1/26 , C12M3/06
CPC分类号： C12P19/02 , C12M21/02 , C12M23/16 , C12M33/14
摘要： A photosynthetic device includes a main body defining a microfluid chamber for causing photosynthesis therein, and a light source, wherein the microfluid chamber is constituted by at least one communication room, a plurality of micro channels respectively and spatially communicated with the communication room, at least one micro injection duct spatially communicated with the communication room, and a plurality of filter plugs spatially connected to the micro channels respectively and the micro injection duct at free ends thereof in order to filter fluid backflow in the micro channels and the micro injection duct. The light source radiates ceaselessly one of the communication room, the plurality of micro channels and the micro injection duct. The photosynthesis is resulted once chloroplasts and normal saline solution are injected into one of the communication room, the plurality of micro channels and the micro injection duct.

8. 发明申请

US20170056659A1 NEURAL SENSING METHOD FOR INTERFERENCE SUPPRESSION AND FOR RETINA APPLICATION AND NEURAL SENSING DEVICE FOR IMPLEMENTING THE SAME 审中-公开
标题翻译：用于干扰抑制和后续应用的神经感测方法和用于实施其的神经感测装置
公开(公告)号：US20170056659A1
公开(公告)日：2017-03-02
申请号：US15345538
申请日：2016-11-08
申请人： Po-Kang Lin
发明人： Po-Kang Lin
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36046 , A61N1/0543
摘要： The present invention provides a neural sensing method for interference suppression, including the steps of: configuring an array of sensing units on a retina of a user; generating a control signal via a control signal generator and generating a plurality of sensed signals via the sensing units of the array of the sensing units; isolating each of the sensed signals via the control signal, thereby suppressing interference via the control signal; and, generating and outputting a processing signal to at least one neuron via a signal processing module with reference to the control signal and the sensed signals. Herein, the sensed signal strength is higher than a sensing threshold of the at least one neuron, and the control signal strength is lower than the sensing threshold of the at least one neuron. In addition, the present invention also provides a neural sensing device for implement the same method.
摘要翻译：本发明提供了一种用于干扰抑制的神经感测方法，包括以下步骤：在用户的视网膜上配置感测单元阵列; 经由控制信号发生器产生控制信号，并经由感测单元的阵列的感测单元产生多个感测信号; 通过控制信号隔离每个感测信号，从而通过控制信号抑制干扰; 并且参照控制信号和感测信号，经由信号处理模块生成并将处理信号输出到至少一个神经元。这里，感测的信号强度高于至少一个神经元的感测阈值，并且控制信号强度低于至少一个神经元的感测阈值。此外，本发明还提供了一种用于实现相同方法的神经感测装置。

9. 发明申请

US20160305951A1 BIOMARKER FOR HUMAN EYES AND METHOD THEREOF 审中-公开
公开(公告)号：US20160305951A1
公开(公告)日：2016-10-20
申请号：US14845746
申请日：2015-09-04
申请人： Po-Kang Lin
发明人： Po-Kang Lin
IPC分类号： G01N33/68 , C07C323/58 , A61B3/135 , C07K14/47
CPC分类号： C07K14/4737 , A61B3/135 , C07C323/58 , G01N33/6815 , G01N33/6893 , G01N2333/4737 , G01N2800/16
摘要： The present invention provides a biomarker for detecting and diagnosing polypoidal choroidal vasculopathy (PCV) of human eyes, including levels of hyperhomocysteinemia that are identified, wherein elevated levels of hyperhomocysteinemia are highly associated with PCV of the human eyes. In addition, the present invention further provides a method for detecting and diagnosing PCV of the human eyes.

10. 发明申请

US20160215245A1 PHOTOSYNTHETIC DEVICE WITH MICROFLUID CHAMBER FOR CAUSING PHOTOSYNTHESIS THEREIN AND METHOD THEREOF 审中-公开
标题翻译：具有微流控室的光敏装置，用于引起其光合作用及其方法
公开(公告)号：US20160215245A1
公开(公告)日：2016-07-28
申请号：US14602450
申请日：2015-01-22
申请人： Po-Kang Lin
发明人： Po-Kang Lin
IPC分类号： C12M1/00 , C12M3/06 , C12M1/26 , C12P19/02
摘要： A photosynthetic device includes a main body defining a microfluid chamber for causing photosynthesis therein, and a light source, wherein the microfluid chamber is constituted by at least one communication room, a plurality of micro channels respectively and spatially communicated with the communication room, at least one micro injection duct spatially communicated with the communication room, and a plurality of filter plugs spatially connected to the micro channels respectively and the micro injection duct at free ends thereof in order to filter fluid backflow in the micro channels and the micro injection duct. The light source radiates ceaselessly one of the communication room, the plurality of micro channels and the micro injection duct. The photosynthesis is resulted once chloroplasts and normal saline solution are injected into one of the communication room, the plurality of micro channels and the micro injection duct.
摘要翻译：光合装置包括限定用于引起光合作用的微流体室的主体和光源，其中微流体室由至少一个通信室，多个微通道分别构成，并且与通信室空间通信至少与通信室空间连通的一个微型注入管道和分别与微通道空间连接的多个过滤嘴塞和微型注射管道在其自由端处，以便过滤微通道和微注射管道中的流体回流。光源不断地辐射通信室，多个微通道和微型注入管道之一。一旦将叶绿体和生理盐水溶液注入到通信室，多个微通道和微注射管之一中，则产生光合作用。

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