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1. 发明申请

US20120289906A1 Method and Assembly for a Drug Delivery Device 有权
标题翻译：药物输送装置的方法和装配
公开(公告)号：US20120289906A1
公开(公告)日：2012-11-15
申请号：US13496337
申请日：2010-09-29
申请人： Christopher Jones , Robert Veasey , Garen Kouyoumjian , Catherine Anne MacDonald , Michael Jugl , Gunther Sendatzki
发明人： Christopher Jones , Robert Veasey , Garen Kouyoumjian , Catherine Anne MacDonald , Michael Jugl , Gunther Sendatzki
IPC分类号： A61M5/00 , B23P11/00
CPC分类号： A61M5/24 , A61M5/3146 , A61M5/31555 , A61M5/3202 , A61M5/3293 , A61M5/344 , A61M5/347 , A61M2005/2407 , A61M2005/2477 , A61M2005/2488 , A61M2205/6045 , A61M2207/00 , Y10T29/49826
摘要： A method for securing a cartridge (4) in a cartridge holder (3) is provided, the method comprising the steps of inserting the cartridge (4) into the cartridge holder (3), the cartridge holder (3) having a proximal end and a distal end, axially displacing the cartridge (4) in a proximal direction with respect to the cartridge holder (3) from a distal initial position to a proximal end position and securing the cartridge (4) in the end position against displacement in the distal direction with respect to the cartridge holder (3). An assembly for a drug delivery device (1) is provided comprising a cartridge (4), an adjusting member (12, 25, 28, 34) and a cartridge holder (3). The cartridge holder (3) has a distal end and a proximal end. The adjusting member (12, 25, 28, 34) is secured to the cartridge holder (3). The adjusting member (12, 25, 28, 34) holds a distal portion of the cartridge (4) at a distance with respect to a distal portion of the cartridge holder (3).
摘要翻译：提供了一种用于将盒（4）固定在盒保持器（3）中的方法，所述方法包括以下步骤：将盒（4）插入盒保持器（3），盒保持器（3）具有近端和一个远端，使药筒（4）相对于药筒保持器（3）的近端方向从远端初始位置轴向移位到近端位置，并将药筒（4）固定在终端位置，防止远端方向相对于盒保持器（3）。提供了一种用于药物输送装置（1）的组件，其包括盒（4），调节构件（12,25,28,34）和盒保持器（3）。药筒保持器（3）具有远端和近端。调节构件（12,25,28,34）固定在盒保持架（3）上。调节构件（12,25,28,34）将盒（4）的远端部分相对于盒保持器（3）的远端部分保持一段距离。

2. 发明授权

US09358340B2 Method and assembly for a drug delivery device 有权
标题翻译：药物输送装置的方法和装配
公开(公告)号：US09358340B2
公开(公告)日：2016-06-07
申请号：US13496337
申请日：2010-09-29
申请人： Christopher Jones , Robert Veasey , Garen Kouyoumjian , Catherine Anne MacDonald , Michael Jugl , Gunther Sendatzki
发明人： Christopher Jones , Robert Veasey , Garen Kouyoumjian , Catherine Anne MacDonald , Michael Jugl , Gunther Sendatzki
IPC分类号： A61M5/24 , A61M5/31 , A61M5/315 , A61M5/32 , A61M5/34
CPC分类号： A61M5/24 , A61M5/3146 , A61M5/31555 , A61M5/3202 , A61M5/3293 , A61M5/344 , A61M5/347 , A61M2005/2407 , A61M2005/2477 , A61M2005/2488 , A61M2205/6045 , A61M2207/00 , Y10T29/49826
摘要： A method for securing a cartridge (4) in a cartridge holder (3) is provided, the method comprising the steps of inserting the cartridge (4) into the cartridge holder (3), the cartridge holder (3) having a proximal end and a distal end, axially displacing the cartridge (4) in a proximal direction with respect to the cartridge holder (3) from a distal initial position to a proximal end position and securing the cartridge (4) in the end position against displacement in the distal direction with respect to the cartridge holder (3). An assembly for a drug delivery device (1) is provided comprising a cartridge (4), an adjusting member (12, 25, 28, 34) and a cartridge holder (3). The cartridge holder (3) has a distal end and a proximal end. The adjusting member (12, 25, 28, 34) is secured to the cartridge holder (3). The adjusting member (12, 25, 28, 34) holds a distal portion of the cartridge (4) at a distance with respect to a distal portion of the cartridge holder (3).
摘要翻译：提供了一种用于将盒（4）固定在盒保持器（3）中的方法，所述方法包括以下步骤：将盒（4）插入盒保持器（3），盒保持器（3）具有近端和一个远端，使药筒（4）相对于药筒保持器（3）的近端方向从远端初始位置轴向移位到近端位置，并将药筒（4）固定在终端位置，防止远端方向相对于盒保持器（3）。提供了一种用于药物输送装置（1）的组件，其包括盒（4），调节构件（12,25,28,34）和盒保持器（3）。药筒保持器（3）具有远端和近端。调节构件（12,25,28,34）固定在盒保持架（3）上。调节构件（12,25,28,34）将盒（4）的远端部分相对于盒保持器（3）的远端部分保持一段距离。

3. 发明授权

US10265478B2 Injection device 有权
公开(公告)号：US10265478B2
公开(公告)日：2019-04-23
申请号：US13497773
申请日：2010-09-29
申请人： Garen Kouyoumjian , Robert Veasey , David Plumptre , Christopher Jones , Catherine Anne MacDonald , James May
发明人： Garen Kouyoumjian , Robert Veasey , David Plumptre , Christopher Jones , Catherine Anne MacDonald , James May
IPC分类号： A61M5/315 , A61M5/24 , A61M5/31
摘要： An injection device (1) for administering a fixed dose of a medication is provided. The injection device (1) comprises a housing (2) wherein a drive mechanism comprising a drive member (3) is at least partially enclosed and a dosing element (34) which is fixed relative to the drive member (3). Here, a dose can be set by rotating the dosing element (34) relative to the housing (2) in a dose set direction (105) and the dose can be dispensed by pushing the dosing element (34) towards the housing (2). Moreover, a method is provided for operating an injection device (1) for the administration of a fixed dose of a medication: A dose can be set by rotating a dosing element (34), a dose can be dispensed by pushing the dosing element (34) towards the housing (2) and a dose can be cancelled by rotating the dosing element (34) in a direction (106) opposite to the dose set direction (105).

4. 发明授权

US09555192B2 Drug delivery device, assembly for a drug delivery device and method for setting up a drug delivery device 有权
标题翻译：药物递送装置，用于药物递送装置的组装和用于设置药物递送装置的方法
公开(公告)号：US09555192B2
公开(公告)日：2017-01-31
申请号：US13497376
申请日：2010-09-29
申请人： Catherine Anne Macdonald , Robert Veasey , Garen Kouyoumjian , Christopher Jones , Alexander Ian Bailey
发明人： Catherine Anne Macdonald , Robert Veasey , Garen Kouyoumjian , Christopher Jones , Alexander Ian Bailey
IPC分类号： A61M5/00 , A61M5/24 , A61M5/31 , A61M5/315 , A61M5/20
CPC分类号： A61M5/24 , A61M5/2448 , A61M5/3146 , A61M5/31571 , A61M5/31578 , A61M2005/2073 , A61M2005/2451
摘要： The instant application is directed to an assembly for a drug delivery device which is arranged to operate in two distinct modes, a priming mode starting from a pre-priming state and a dispense mode operating in a post-priming state, and a drug delivery device comprising this assembly. The assembly comprises a dose member, an actuating member and a piston rod which is configured to act on a bung of an assembled cartridge containing the drug. In the pre-priming state the actuating member is configured to be moved by a user such that the movement of the actuating member causes a movement of the dose member and such that the movement of the dose member causes a movement of the piston rod. In the post-priming state the dose member is configured to be moved by a user without causing a movement of the actuating member in order to perform a set and dispense action of the drug delivery device.
摘要翻译：本申请涉及用于药物递送装置的组件，其被布置成以两种不同模式操作，从预灌注状态开始的启动模式和以后启动状态操作的分配模式，以及药物递送装置包括该组件。组件包括剂量构件，致动构件和活塞杆，其构造成作用在装有药物的组装好的药筒的栓上。在预灌注状态下，致动构件被构造成由使用者移动，使得致动构件的移动导致剂量构件的运动，并且使得剂量构件的移动导致活塞杆的移动。在后启动状态中，剂量构件被构造成由使用者移动而不引起致动构件的移动，以便执行药物递送装置的集合和分配动作。

5. 发明授权

US09186460B2 Assembly of a drug delivery device 有权
标题翻译：组装药物输送装置
公开(公告)号：US09186460B2
公开(公告)日：2015-11-17
申请号：US13498440
申请日：2010-09-29
申请人： Catherine Anne MacDonald , Robert Veasey , Garen Kouyoumjian , Christopher Jones , Andrew Mark Lindsay , Michael Bainton
发明人： Catherine Anne MacDonald , Robert Veasey , Garen Kouyoumjian , Christopher Jones , Andrew Mark Lindsay , Michael Bainton
IPC分类号： A61M5/315 , A61M5/24 , A61M5/31
CPC分类号： A61M5/24 , A61M5/2448 , A61M5/3146 , A61M5/3155 , A61M5/31551 , A61M5/31555 , A61M5/3156 , A61M5/3158 , A61M5/31593 , A61M2005/2407 , A61M2005/2492 , A61M2205/583 , A61M2205/6018
摘要： An assembly of a drug delivery device comprises a body (10) having a distal end (11) and a proximal end (12), a drive assembly (4) arranged substantially within the body (10) to facilitate dispense of a medicinal product and a button member (5) arranged at the proximal end (12) of the body (10) and adapted to act upon the drive assembly (4). The drive assembly (4) has an initial pre-ready state, a transient state and a ready state; in the pre-ready and transient states the button member (5) is twistable with respect to the body (10) to act upon the drive assembly (4) and wherein in the ready state the button member (5) is axially moveable but not substantially twistable with respect to the body (10) to act upon the drive assembly (4) to dispense a dose of the medicinal product.
摘要翻译：药物递送装置的组件包括具有远端（11）和近端（12）的主体（10），基本上设置在主体（10）内的驱动组件（4），以便于分配药物，布置在主体（10）的近端（12）处并适于作用在驱动组件（4）上的按钮构件（5）。驱动组件（4）具有初始预准备状态，瞬态状态和就绪状态; 在预准备和瞬态状态下，按钮构件（5）相对于主体（10）可扭转以作用在驱动组件（4）上，并且其中在就绪状态下，按钮构件（5）可轴向移动但不能相对于主体（10）基本上可扭转以作用于驱动组件（4）以分配一定剂量的药用产品。

6. 发明申请

US20120310206A1 Injection Device 审中-公开
标题翻译：注射装置
公开(公告)号：US20120310206A1
公开(公告)日：2012-12-06
申请号：US13497773
申请日：2010-09-29
申请人： Garen Kouyoumjian , Robert Veasey , David Plumptre , Christopher Jones , Catherine Anne MacDonald , James May
发明人： Garen Kouyoumjian , Robert Veasey , David Plumptre , Christopher Jones , Catherine Anne MacDonald , James May
IPC分类号： A61M5/315
CPC分类号： A61M5/31543 , A61M5/24 , A61M5/3129 , A61M5/31525 , A61M5/31541 , A61M5/31551 , A61M5/31558 , A61M5/3156 , A61M5/31585 , A61M2005/2407 , A61M2005/2488 , A61M2205/581 , A61M2205/582
摘要： An injection device (1) for administering a fixed dose of a medication is provided. The injection device (1) comprises a housing (2) wherein a drive mechanism comprising a drive member (3) is at least partially enclosed and a dosing element (34) which is fixed relative to the drive member (3). Here, a dose can be set by rotating the dosing element (34) relative to the housing (2) in a dose set direction (105) and the dose can be dispensed by pushing the dosing element (34) towards the housing (2). Moreover, a method is provided for operating an injection device (1) for the administration of a fixed dose of a medication: A dose can be set by rotating a dosing element (34), a dose can be dispensed by pushing the dosing element (34) towards the housing (2) and a dose can be cancelled by rotating the dosing element (34) in a direction (106) opposite to the dose set direction (105).
摘要翻译：提供了一种用于施用固定剂量的药物的注射装置（1）。注射装置（1）包括壳体（2），其中包括驱动构件（3）的驱动机构至少部分地封闭，并且相对于驱动构件（3）固定的计量元件（34）。这里，可以通过以剂量设定方向（105）相对于壳体（2）旋转计量元件（34）来设定剂量，并且可以通过将剂量元件（34）推向壳体（2）来分配剂量，。此外，提供了一种用于操作用于施用固定剂量的药物的注射装置（1）的方法：剂量可以通过旋转剂量元件（34）来设定，剂量可以通过推动剂量元件（ 34）朝向壳体（2），并且可以通过在与剂量设定方向（105）相反的方向（106）旋转定量元件（34）来消除剂量。

7. 发明申请

US20120310172A1 Drug Delivery Device 审中-公开
标题翻译：药物输送装置
公开(公告)号：US20120310172A1
公开(公告)日：2012-12-06
申请号：US13498610
申请日：2010-09-29
申请人： Catherine Anne MacDonald , Robert Veasey , Garen Kouyoumjian , Christopher Jones , Andrew Mark Lindsay , Michael Bainton
发明人： Catherine Anne MacDonald , Robert Veasey , Garen Kouyoumjian , Christopher Jones , Andrew Mark Lindsay , Michael Bainton
IPC分类号： A61M5/31
CPC分类号： A61M5/31525 , A61M5/31555 , A61M2005/2073
摘要： A drug delivery device (10) is given, comprising a body (12) and a moveable button member (14), wherein in a pre-ready state of the drug delivery device (10) there is a misalignment between the body (12) and the button member (14). This misalignment is perceivable by a user of the drug delivery device (10). In a ready state of the drug delivery device (10), the button member (14) and the body (12) are aligned and the alignment is perceivable by a user of the drug delivery device (10).
摘要翻译：给药药物输送装置（10）包括主体（12）和可移动的按钮部件（14），其中在药物输送装置（10）的预准备状态下，主体（12）之间存在未对准和按钮构件（14）。药物输送装置（10）的使用者可以察觉到这种错位。在药物递送装置（10）的准备状态下，按钮构件（14）和主体（12）对准，并且对准可由药物输送装置（10）的使用者察觉。

8. 发明申请

US20120283653A1 Assembly for a Drug Delivery Device 有权
标题翻译：药物输送装置的装配
公开(公告)号：US20120283653A1
公开(公告)日：2012-11-08
申请号：US13395701
申请日：2010-09-29
申请人： Catherine Anne MacDonald , Robert Veasey , Christopher Jones , Garen Kouyoumjian
发明人： Catherine Anne MacDonald , Robert Veasey , Christopher Jones , Garen Kouyoumjian
IPC分类号： A61M5/315
CPC分类号： A61M5/24 , A61M5/3146 , A61M5/31543 , A61M5/31555 , A61M5/31556 , A61M5/3156 , A61M5/3158 , A61M2005/2407 , A61M2005/2488 , A61M2005/2492
摘要： A resettable drive mechanism for a drug delivery device (1) comprises a piston rod assembly (32) and an interaction member (23). The piston rod assembly (32) comprises a guide track (18) running along the piston rod assembly (32), the guide track (18) comprising at least one delivery section (18A) and at least one reset section (18B). The reset section (18B) is arranged to continue the delivery section (18A). The delivery section (18A) comprises at least one blocking means (19). The interaction member (23) is configured to cooperate with the guide track (18). For delivering a dose of a drug (24), the piston rod assembly (32) is axially displaceable in a dose delivery direction away from an axial starting position, the interaction member (23) cooperating with the delivery section (18A) and the blocking means (19) passing the interaction member (23) when the piston rod assembly (32) is displaced in the dose delivery direction. Axial displacement of the piston rod assembly (32) towards the axial starting position is prevented by mechanical interaction of the blocking means (19) and the interaction member (23) when the interaction member (23) cooperates with the delivery section (18A). For resetting the drug delivery device (1), the interaction member (23) is configured to cooperate with the reset section (18B), the piston rod assembly (32) being axially displaced towards the axial starting position, the blocking means (19) being offset from the interaction member (23) and passing the axial position of the interaction member (23) when the piston rod assembly (32) is axially displaced towards the axial starting position. Also, a piston rod assembly (32) is proposed.
摘要翻译：用于药物输送装置（1）的可重置驱动机构包括活塞杆组件（32）和相互作用构件（23）。活塞杆组件（32）包括沿着活塞杆组件（32）延伸的导轨（18），导轨（18）包括至少一个输送部分（18A）和至少一个复位部分（18B）。复位部分（18B）布置成继续传送部分（18A）。输送部分（18A）包括至少一个阻挡装置（19）。相互作用构件（23）构造成与导轨（18）配合。为了递送药物（24）的剂量，活塞杆组件（32）可以在远离轴向起始位置的剂量递送方向上轴向移位，相互作用构件（23）与输送段（18A）配合并阻塞当活塞杆组件（32）在剂量递送方向上移位时，装置（19）使相互作用构件（23）通过。当相互作用构件（23）与输送段（18A）配合时，通过阻挡装置（19）和相互作用构件（23）的机械相互作用来防止活塞杆组件（32）朝向轴向起始位置的轴向位移。为了复位药物输送装置（1），相互作用构件（23）构造成与复位部分（18B）配合，活塞杆组件（32）朝着轴向起始位置轴向移位，阻挡装置（19）当所述活塞杆组件（32）朝向所述轴向起始位置轴向移位时，所述相互作用构件（23）偏离所述相互作用构件（23）的轴向位置。此外，提出了一种活塞杆组件（32）。

9. 发明申请

US20120283649A1 DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE AND USE OF A RESET MEMBER FOR A DRIVE MECHANISM 有权
标题翻译：用于药物递送装置的驱动机构和用于驱动机构的复位部件的使用
公开(公告)号：US20120283649A1
公开(公告)日：2012-11-08
申请号：US13395898
申请日：2010-09-29
申请人： Robert Veasey , Simon Lewis Bilton , Christopher Jones , Garen Kouyoumjian , Catherine Anne Macdonald
发明人： Robert Veasey , Simon Lewis Bilton , Christopher Jones , Garen Kouyoumjian , Catherine Anne Macdonald
IPC分类号： A61M5/315
CPC分类号： A61M5/31535 , A61M5/24 , A61M5/31543 , A61M5/31555 , A61M5/3156 , A61M5/3158 , A61M5/31593 , A61M2005/2407
摘要： A plunger and a lever are arranged in a body and provided with engaging elements engaging the lever with the plunger. The lever is disengageable from the plunger by a shift of the lever, thus enabling a movement of the plunger relatively to the body in the proximal direction.
摘要翻译：柱塞和杠杆布置在主体中并且设置有与杠杆与柱塞接合的接合元件。杠杆通过杠杆的移动而与柱塞脱离，从而使得柱塞能够在近端方向上相对于身体移动。

10. 发明申请

US20120283648A1 DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE 有权
标题翻译：用于药物递送装置的驱动机构
公开(公告)号：US20120283648A1
公开(公告)日：2012-11-08
申请号：US13496536
申请日：2010-09-29
申请人： Robert Veasey , Simon Lewis Bilton , Christopher Jones , Garen Kouyoumjian , Catherine Anne MacDonald
发明人： Robert Veasey , Simon Lewis Bilton , Christopher Jones , Garen Kouyoumjian , Catherine Anne MacDonald
IPC分类号： A61M5/31
CPC分类号： A61M5/24 , A61M5/31541 , A61M5/31555 , A61M5/31558 , A61M5/31561 , A61M5/31575 , A61M5/31593 , A61M2005/2407 , A61M2005/2488 , A61M2005/3142
摘要： A first output member is rotatable around an axis relatively to the body. A second output member is movable relatively to the body along the axis. The first output member and the second output member are rotationally coupled. A drive feature is provided to generate a rotation of the first output member. A part which is removable from and attachable to the body is provided so that the first output member is unidirectionally rotationally coupled with the drive feature when the part is attached to the body.
摘要翻译：第一输出构件可绕相对于身体的轴线旋转。第二输出构件可相对于主体沿轴线移动。第一输出构件和第二输出构件被旋转地联接。提供驱动特征以产生第一输出构件的旋转。提供从主体可移除并可附接到本体的部分，使得当部件附接到主体时，第一输出部件与驱动部件单方向地旋转耦合。

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