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1. 发明授权

US09031634B2 Chemical shift markers for improved wireless fiducial marker tracking 有权
标题翻译：用于改进无线基准标记跟踪的化学位移标记
公开(公告)号：US09031634B2
公开(公告)日：2015-05-12
申请号：US10514307
申请日：2003-05-15
申请人： Christopher Flask , Jonathan Lewin , Daniel Elgort , Ken Pin Wang , Eddy Wong , Jeffrey Duerk
发明人： Christopher Flask , Jonathan Lewin , Daniel Elgort , Ken Pin Wang , Eddy Wong , Jeffrey Duerk
IPC分类号： A61B5/055 , G01R33/28 , A61B19/00 , A61B5/06
CPC分类号： G01R33/285 , A61B5/055 , A61B5/06 , A61B90/39 , A61B2090/3954
摘要： A new and improved method for tracking and/or spatial localization of an invasive device in Magnetic Resonance Imaging (MRI) is provided. The invention includes providing an invasive device including a marker having a chemically shifted signal source with a resonant frequency different from the chemical species of the subject to be imaged, applying a pulse sequence, detecting the resulting RF magnetic resonance signals, and determining the 3D coordinates of the marker. The invention also includes generating scan planes and reconstructing an image from the detected signals to generate an image having the marker contrasted from the subject. The invasive device includes a marker having a chemically shifted signal source which has a resonant frequency different from the chemical species of the subject to be imaged for use in tracking the device during imaging.
摘要翻译：提供了一种用于磁共振成像（MRI）中的侵入性装置的跟踪和/或空间定位的新的和改进的方法。本发明包括提供一种侵入性装置，其包括具有化学位移信号源的标记物，其具有不同于待成像对象的化学物质的共振频率，应用脉冲序列，检测所得到的RF磁共振信号，以及确定3D坐标的标记。本发明还包括产生扫描平面并从检测到的信号重建图像以产生具有与被摄体对比的标记的图像。侵入性装置包括具有化学位移信号源的标记，其具有与被成像对象的化学物种不同的共振频率，以用于在成像期间跟踪装置。

2. 发明申请

US20060173277A1 Adaptive imaging parameters with MRI 有权
公开(公告)号：US20060173277A1
公开(公告)日：2006-08-03
申请号：US11050341
申请日：2005-02-03
申请人： Daniel Elgort , Eddy Wong , Claudia Hillenbrand , Jonathan Lewin , Jeffrey Duerk
发明人： Daniel Elgort , Eddy Wong , Claudia Hillenbrand , Jonathan Lewin , Jeffrey Duerk
IPC分类号： A61B5/05
CPC分类号： G01R33/54
摘要： Systems, methodologies, media, and other embodiments associated with automatically adapting MRI controlling parameters are described. One exemplary method embodiment includes configuring an MRI apparatus to acquire MR signal data using a non-rectilinear trajectory. The example method may also include acquiring MR signals, transforming the MR signals into image data, and selectively adapting the MRI controlling parameters based, at least in part, on information associated with the MR signals.

3. 发明申请

US20050054913A1 Adaptive tracking and MRI-guided catheter and stent placement 审中-公开
标题翻译：自适应跟踪和MRI导向导管和支架放置
公开(公告)号：US20050054913A1
公开(公告)日：2005-03-10
申请号：US10839861
申请日：2004-05-05
申请人： Jeffrey Duerk , Daniel Elgort , Chris Flask , Claudia Hillenbrand , Jonathan Lewin , Frank Wacker , Eddy Wong
发明人： Jeffrey Duerk , Daniel Elgort , Chris Flask , Claudia Hillenbrand , Jonathan Lewin , Frank Wacker , Eddy Wong
IPC分类号： G01R33/28 , G01R33/563 , G06T11/00 , A61B5/05
CPC分类号： G01R33/287 , G01R33/563
摘要： A method of automatically adjusting at least one MR image parameter for an interventional procedure includes adaptively tracking an MR micro-coil catheter and automatically updating an imaging scan plane's position and orientation, as well as other features including, but not limited to, field-of-view, resolution, temporal resolution, slice thickness, tip angle, and TE. The disclosed system provides a more natural interface for a physician operating the MR scanner during an interventional procedure. The scanner can react to changes in the clinical environment and automatically adjust a number of image parameters. For example, during catheter insertion, images are acquired at lower resolutions, and possibly larger fields of view, to help facilitate faster updates and tracking. Once the catheter reaches a target area in the tissue and its motion slows, an MR image of higher resolution, and possibly lower field of view, is acquired.
摘要翻译：自动调整用于介入手术的至少一个MR图像参数的方法包括自适应跟踪MR微线圈导管并自动更新成像扫描平面的位置和取向，以及其它特征，包括但不限于：视图，分辨率，时间分辨率，切片厚度，尖角和TE。所公开的系统为在介入过程期间操作MR扫描仪的医生提供更自然的界面。扫描仪可以对临床环境的变化做出反应，并自动调整多个图像参数。例如，在导管插入期间，以较低分辨率和可能更大的视野获取图像，以帮助促进更快速的更新和跟踪。一旦导管到达组织中的目标区域并且其运动减慢，则获得更高分辨率和可能较低视野的MR图像。

4. 发明申请

US20050054914A1 MRI probe designs for minimally invasive intravascular tracking and imaging applications 有权
标题翻译：用于微创血管内跟踪和成像应用的MRI探针设计
公开(公告)号：US20050054914A1
公开(公告)日：2005-03-10
申请号：US10839922
申请日：2004-05-05
申请人： Jeffrey Duerk , Daniel Elgort , Chris Flask , Claudia Hillenbrand , Jonathan Lewin , Eddy Wong
发明人： Jeffrey Duerk , Daniel Elgort , Chris Flask , Claudia Hillenbrand , Jonathan Lewin , Eddy Wong
IPC分类号： G01R33/28 , G01R33/563 , G06T11/00 , A61B5/05
CPC分类号： G01R33/287 , G01R33/563
摘要： A probe suitable for attachment to, or incorporation in, a medical interventional device, such as a catheter, and which may be employed for tracking, imaging, or both, includes a first material having an MR resonance frequency distinct from a resonance frequency of a second material adjacent to the first material. The probe may include one or more coils, or it may be wireless, that is, it may have no coils. Some probe configurations are directed at tracking or imaging of vascular vessels or tissue, and configurations allow both tracking and imaging.
摘要翻译：适于附着或并入医疗介入装置（例如导管）中并且可用于跟踪，成像或两者的探针包括具有与共振频率不同的MR共振频率的第一材料与第一材料相邻的第二材料。探头可以包括一个或多个线圈，或者它可以是无线的，即它可以没有线圈。一些探针配置针对血管或组织的跟踪或成像，并且配置允许跟踪和成像。

5. 发明申请

US20060116574A1 Extended-coverage imaging coil 有权
标题翻译：扩展覆盖成像线圈
公开(公告)号：US20060116574A1
公开(公告)日：2006-06-01
申请号：US11000250
申请日：2004-11-30
申请人： Eddy Wong , Claudia Hillenbrand , Jonathan Lewin , Jeffrey Duerk
发明人： Eddy Wong , Claudia Hillenbrand , Jonathan Lewin , Jeffrey Duerk
IPC分类号： A61B6/00 , A61M25/00
CPC分类号： G01R33/34084 , G01R33/287 , G01R33/34053 , G01R33/341
摘要： Extended-coverage magnetic resonance imaging coils with optimized homogeneity in longitudinal sensitivity are described. One exemplary coil includes four elements, where two of the elements are opposed-solenoid imaging elements and two of the elements are single loop imaging elements.
摘要翻译：描述了具有优化的纵向灵敏度均匀性的扩展覆盖磁共振成像线圈。一个示例性线圈包括四个元件，其中两个元件是相对的电磁成像元件，并且两个元件是单环成像元件。

6. 发明授权

US07606612B2 System and method to perform parallel imaging 有权
标题翻译：执行并行成像的系统和方法
公开(公告)号：US07606612B2
公开(公告)日：2009-10-20
申请号：US11132989
申请日：2005-05-19
申请人： Claudia M. Hillenbrand , Mark A. Griswold , Eddy Wong , Jeffrey Duerk
发明人： Claudia M. Hillenbrand , Mark A. Griswold , Eddy Wong , Jeffrey Duerk
IPC分类号： A61B5/055 , G01V3/00
CPC分类号： A61B5/055
摘要： A system and method to perform parallel MR imaging are disclosed. The system comprises an MR imaging machine and a probe having at least two MR RF reception coils. Each coil of the probe is operationally connected to a separate receiver channel of the MR imaging machine. The MR imaging machine implements a partially parallel acquisition method to excite precessing nuclear spins, in and around an internal segment of a patient into which the probe is inserted, and to use the coils of the catheter to simultaneously sample a plurality of response signals to form reduced k-space data sets for each of the coils. The plurality of response signals represent nuclear magnetic resonance signals arising from the precessing nuclear spins. The reduced k-space data sets are further processed by the MR imaging machine to generate a full volume dataset of a region in and around the vessel.
摘要翻译：公开了一种执行并行MR成像的系统和方法。该系统包括MR成像机和具有至少两个MR RF接收线圈的探针。探针的每个线圈可操作地连接到MR成像机的单独接收器通道。 MR成像机实现部分平行采集方法，以便在插入探头的患者的内部段内和周围激发进动的核自旋，并且使用导管的线圈同时采样多个响应信号以形成减少每个线圈的k空间数据集。多个响应信号表示从进动的核自旋产生的核磁共振信号。缩小的k空间数据集由MR成像机进一步处理以产生血管内和周围区域的完整体积数据集。

7. 发明授权

US09086467B2 Adaptive imaging parameters with MRI 有权
标题翻译：自适应成像参数与MRI
公开(公告)号：US09086467B2
公开(公告)日：2015-07-21
申请号：US12624903
申请日：2009-11-24
申请人： Daniel Elgort , Eddy Wong , Claudia Hillenbrand , Jonathan S. Lewin , Jeffrey L. Duerk
发明人： Daniel Elgort , Eddy Wong , Claudia Hillenbrand , Jonathan S. Lewin , Jeffrey L. Duerk
IPC分类号： A61B5/00 , G01R33/54
CPC分类号： G01R33/54
摘要： Systems, methodologies, media, and other embodiments associated with automatically adapting MRI controlling parameters are described. One exemplary method embodiment includes configuring an MRI apparatus to acquire MR signal data using a non-rectilinear trajectory. The example method may also include acquiring MR signals, transforming the MR signals into image data, and selectively adapting the MRI controlling parameters based, at least in part, on information associated with the MR signals.
摘要翻译：描述了与自动适应MRI控制参数相关联的系统，方法，介质和其他实施例。一个示例性方法实施例包括配置MRI装置以使用非直线轨迹来获取MR信号数据。该示例性方法还可以包括获取MR信号，将MR信号变换为图像数据，以及至少部分地基于与MR信号相关联的信息来选择性地调整MRI控制参数。

8. 发明授权

US07643864B2 Adaptive imaging parameters with MRI 有权
标题翻译：自适应成像参数与MRI
公开(公告)号：US07643864B2
公开(公告)日：2010-01-05
申请号：US11050341
申请日：2005-02-03
申请人： Daniel Elgort , Eddy Wong , Claudia Hillenbrand , Jonathan S. Lewin , Jeffrey L. Duerk
发明人： Daniel Elgort , Eddy Wong , Claudia Hillenbrand , Jonathan S. Lewin , Jeffrey L. Duerk
IPC分类号： A61B5/00
CPC分类号： G01R33/54
摘要： Systems, methodologies, media, and other embodiments associated with automatically adapting MRI controlling parameters are described. One exemplary method embodiment includes configuring an MRI apparatus to acquire MR signal data using a non-rectilinear trajectory. The example method may also include acquiring MR signals, transforming the MR signals into image data, and selectively adapting the MRI controlling parameters based, at least in part, on information associated with the MR signals.
摘要翻译：描述了与自动适应MRI控制参数相关联的系统，方法，介质和其他实施例。一个示例性方法实施例包括配置MRI装置以使用非直线轨迹来获取MR信号数据。该示例性方法还可以包括获取MR信号，将MR信号变换为图像数据，以及至少部分地基于与MR信号相关联的信息来选择性地调整MRI控制参数。

9. 发明申请

US20060293586A1 System and method to perform parallel imaging 有权
公开(公告)号：US20060293586A1
公开(公告)日：2006-12-28
申请号：US11132989
申请日：2005-05-19
申请人： Claudia Hillenbrand , Mark Griswold , Eddy Wong , Jeffrey Duerk
发明人： Claudia Hillenbrand , Mark Griswold , Eddy Wong , Jeffrey Duerk
IPC分类号： A61B5/05
CPC分类号： A61B5/055
摘要： A system and method to perform parallel MR imaging are disclosed. The system comprises an MR imaging machine and a probe having at least two MR RF reception coils. Each coil of the probe is operationally connected to a separate receiver channel of the MR imaging machine. The MR imaging machine implements a partially parallel acquisition method to excite precessing nuclear spins, in and around an internal segment of a patient into which the probe is inserted, and to use the coils of the catheter to simultaneously sample a plurality of response signals to form reduced k-space data sets for each of the coils. The plurality of response signals represent nuclear magnetic resonance signals arising from the precessing nuclear spins. The reduced k-space data sets are further processed by the MR imaging machine to generate a full volume dataset of a region in and around the vessel.

10. 外观设计

USD485238S1 Small form factor pluggable packaging 失效
标题翻译：小尺寸可插拔包装
公开(公告)号：USD485238S1
公开(公告)日：2004-01-13
申请号：US29179968
申请日：2003-04-16
申请人： Jeng-Yih Hwang , Wayne Huang , Eddy Wong , Hung Tieu
设计人： Jeng-Yih Hwang , Wayne Huang , Eddy Wong , Hung Tieu

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