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1. 发明授权

US07136518B2 Methods and apparatus for displaying diagnostic data 失效
标题翻译：用于显示诊断数据的方法和装置
公开(公告)号：US07136518B2
公开(公告)日：2006-11-14
申请号：US10418902
申请日：2003-04-18
申请人： Christopher E. Griffin , Chunsheng Jiang , Jean-Pierre Schott , Kevin T. Schomacker , Ross F. Flewelling , Charles C. Abele
发明人： Christopher E. Griffin , Chunsheng Jiang , Jean-Pierre Schott , Kevin T. Schomacker , Ross F. Flewelling , Charles C. Abele
IPC分类号： G06K9/00 , G06K9/62 , G09G5/00
CPC分类号： A61B5/7264 , A61B5/0059 , A61B5/7257 , A61B5/7267 , G01N21/274 , G01N21/31 , G06K9/00147 , G06T7/223 , G06T11/206 , G06T2207/10016 , G06T2207/10068 , G06T2207/30024
摘要： The invention provides methods for displaying diagnostic results obtained from a tissue sample. In general, the invention assigns tissue-class probability values to discrete regions of a patient sample, and creates an overlay for displaying the results. The overlay facilitates display of the tissue class probabilities in a way that reflects the diagnostic relevance of the data. For example, methods of the invention comprise applying filtering and color-blending techniques in order to facilitate display of diagnostic results.
摘要翻译：本发明提供用于显示从组织样品获得的诊断结果的方法。通常，本发明将组织类概率值分配给患者样本的离散区域，并创建用于显示结果的覆盖。覆盖有助于以反映数据的诊断相关性的方式显示组织类概率。例如，本发明的方法包括应用过滤和色混技术以便于显示诊断结果。

2. 发明授权

US07282723B2 Methods and apparatus for processing spectral data for use in tissue characterization 失效
标题翻译：用于处理用于组织表征的光谱数据的方法和装置
公开(公告)号：US07282723B2
公开(公告)日：2007-10-16
申请号：US10418415
申请日：2003-04-18
申请人： Kevin T. Schomacker , Thomas M. Meese , Ross F. Flewelling , Chunsheng Jiang , Christopher E. Griffin , Alex Zelenchuk
发明人： Kevin T. Schomacker , Thomas M. Meese , Ross F. Flewelling , Chunsheng Jiang , Christopher E. Griffin , Alex Zelenchuk
IPC分类号： A61B5/04
CPC分类号： G01N21/6456 , A61B5/0059 , A61B5/725 , A61B5/7257 , A61B5/7264 , A61B5/7267 , G01N21/31 , G01N2021/6423 , G06K9/00147
摘要： The invention provides methods for processing tissue-derived spectral data for use in a tissue classification algorithm. Methods of the invention comprise application of spectral and/or image masks for automatically separating ambiguous or unclassifiable spectral data from valid spectral data. The invention improves the accuracy of tissue classification, in part, by properly identifying and accounting for spectral data from tissue regions that are affected by an obstruction and/or regions that lie outside a diagnostic zone of interest.
摘要翻译：本发明提供了用于处理用于组织分类算法的组织衍生光谱数据的方法。本发明的方法包括应用光谱和/或图像掩模，用于自动将不明确或不可分类的光谱数据与有效光谱数据分离。本发明部分地通过适当地识别和计算受阻塞物和/或位于感兴趣的诊断区域之外的区域的组织区域的光谱数据来提高组织分类的准确性。

3. 发明申请

US20060013454A1 Systems for identifying, displaying, marking, and treating suspect regions of tissue 审中-公开
标题翻译：用于识别，显示，标记和处理组织可疑区域的系统
公开(公告)号：US20060013454A1
公开(公告)日：2006-01-19
申请号：US10530741
申请日：2004-04-16
申请人： Ross Flewelling , Christopher Griffin , Chunsheng Jiang , Jean-Pierre Schott , Kevin Schomacker
发明人： Ross Flewelling , Christopher Griffin , Chunsheng Jiang , Jean-Pierre Schott , Kevin Schomacker
IPC分类号： G06K9/00
CPC分类号： G01N21/6428 , A61B1/0005 , A61B1/00142 , A61B1/042 , A61B1/043 , A61B5/0068 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/6886 , A61B5/7257 , A61B5/7264 , A61B5/7267 , A61B2560/0233 , G01N21/274 , G01N21/31 , G06K9/4652 , G06T7/0012 , G06T11/00 , G06T2207/30024
摘要： The invention provides systems for automatically localizing areas of disease within a tissue sample using fluorescence spectra, reflectance spectra, and video images obtained from the sample. The invention further provides systems for displaying, marking, and treating the identified areas so that healthy surrounding tissue suffers minimal impact upon treatment and/or excision of the diseased tissue. The invention facilitates minimally-invasive treatment by accurately directing treatment to only those areas that are identified as diseased.
摘要翻译：本发明提供了使用荧光光谱，反射光谱和从样品获得的视频图像来自动定位组织样本内的疾病区域的系统。本发明还提供用于显示，标记和处理所识别的区域的系统，使得健康的周围组织对患病组织的治疗和/或切除的影响最小。本发明通过将治疗精确地指向仅被鉴定为患病的那些区域来促进微创治疗。

4. 发明授权

US07469160B2 Methods and apparatus for evaluating image focus 失效
标题翻译：用于评估图像焦点的方法和装置
公开(公告)号：US07469160B2
公开(公告)日：2008-12-23
申请号：US10419181
申请日：2003-04-18
申请人： Perry S. Banks , Chunsheng Jiang , Karen M. Twietmeyer , Richard M. Morrell , Charles C. Abele
发明人： Perry S. Banks , Chunsheng Jiang , Karen M. Twietmeyer , Richard M. Morrell , Charles C. Abele
IPC分类号： A61B6/00
CPC分类号： A61B5/0059 , A61B5/7257 , A61B5/7264 , A61B5/7267 , G01N21/31
摘要： The invention provides methods of focusing an instrument for the acquisition of optical data from a tissue sample. Methods of the invention allow rapid focusing in the context of a diagnostic procedure in which rapid data acquisition is desirable. For example, inventive methods allow a user to focus an optical instrument quickly enough to obtain data within an optimal window of time following application of a chemical agent to the tissue. In one embodiment, a user focuses an optical instrument by aligning laser spots projected onto a tissue sample within rings that are superimposed at predetermined locations within the user's visual field. Preferred methods of the invention further comprise automatic validation to detect whether the spots are sufficiently well-aligned.
摘要翻译：本发明提供了一种聚焦仪器以从组织样本获取光学数据的方法。本发明的方法允许在需要快速数据采集的诊断程序的上下文中进行快速聚焦。例如，本发明的方法允许用户将光学仪器快速聚焦，以便在向组织施加化学试剂之后的最佳时间窗口内获得数据。在一个实施例中，用户通过将投影在组织样本上的激光点对准在与用户的视野内的预定位置叠加的环内的环境中来聚焦光学仪器。本发明的优选方法还包括自动验证以检测斑点是否足够良好地对齐。

5. 发明申请

US20110144462A1 MINIATURIZED MULTI-SPECTRAL IMAGER FOR REAL-TIME TISSUE OXYGENATION MEASUREMENT 审中-公开
标题翻译：用于实时组织氧化测量的微型多光谱成像仪
公开(公告)号：US20110144462A1
公开(公告)日：2011-06-16
申请号：US12407633
申请日：2009-03-19
申请人： Rick Lifsitz , Chunsheng Jiang , Oleg Gusyatin , Ilya Shubenstov
发明人： Rick Lifsitz , Chunsheng Jiang , Oleg Gusyatin , Ilya Shubenstov
IPC分类号： A61B5/1455
CPC分类号： G01N21/31 , A61B5/0059 , A61B5/14552 , G01J3/02 , G01J3/0272 , G01J3/2823 , G01J3/40 , G01N2021/3144 , G01N2021/3155
摘要： A portable multi-spectral imaging system and device is disclosed. The system includes at least one image acquisition device for acquiring an image from a subject, a filtering device to filter the light received by the image acquisition device, a processor for processing the image acquired by the image acquisition device, and a display. There is software running on the processor that determines oxygenation values of the subject based on the processed image.
摘要翻译：公开了便携式多光谱成像系统和装置。该系统包括用于从被摄体获取图像的至少一个图像获取装置，用于对由图像采集装置接收的光进行滤波的滤波装置，用于处理由图像获取装置获取的图像的处理器和显示器。在处理器上运行的软件基于处理的图像来确定对象的氧合值。

6. 发明申请

US20140312349A1 THIN FILM TRANSISTOR AND MANUFACTURING METHOD THEREOF AND ARRAY SUBSTRATE INCLUDING THE THIN FILM TRANSISTOR 审中-公开
标题翻译：薄膜晶体管及其制造方法及其包括薄膜晶体管的阵列衬底
公开(公告)号：US20140312349A1
公开(公告)日：2014-10-23
申请号：US13697409
申请日：2012-07-17
申请人： Chunsheng Jiang
发明人： Chunsheng Jiang
IPC分类号： H01L29/786 , H01L29/66
CPC分类号： H01L29/78675 , H01L21/26526 , H01L27/1277 , H01L29/66757 , H01L29/78618
摘要： An embodiment of the present invention provides a thin film transistor and a manufacturing method thereof and an array substrate comprising the thin film transistor. The method comprises: depositing an amorphous layer on a substrate, and patterning the amorphous layer so as to form an active layer comprising a source region, a drain region and a channel region; forming a gate insulating layer and a gate electrode above the channel region; depositing an induction metal layer on the substrate on which the gate electrode is formed; doping impurity into the source region and the drain region by an ion implanting process and bombarding part of the induction metal into the source region and the drain region; removing the induction metal layer; performing a thermal treatment to the doped active layer so that the impurity is activated and the metal induced crystallization and the metal induced lateral crystallization occur in the active layer due to the induction metal, converting the amorphous silicon to polysilicon in the source region, the drain region and the channel region of the active layer; and forming a source electrode and a drain electrode.
摘要翻译：本发明的实施例提供一种薄膜晶体管及其制造方法以及包括该薄膜晶体管的阵列基板。该方法包括：在衬底上沉积非晶层，并对非晶层进行构图以形成包括源极区，漏极区和沟道区的有源层; 在沟道区上形成栅极绝缘层和栅电极; 在其上形成有栅电极的基板上沉积感应金属层; 通过离子注入工艺将杂质掺杂到源区和漏区，并将部分感应金属轰击到源区和漏区; 去除感应金属层; 对掺杂的有源层进行热处理，使得杂质被激活，并且由于感应金属而在有源层中发生金属诱导的结晶和金属诱导的横向结晶，将非晶硅转换成源区中的多晶硅，漏极区域和有源层的沟道区域; 以及形成源电极和漏电极。

7. 发明申请

US20140154703A1 CIRCULATING TUMOR CELL CAPTURE ON A MICROFLUIDIC CHIP INCORPORATING BOTH AFFINITY AND SIZE 审中-公开
标题翻译：流式细胞仪检测微血管芯片，包括两个大小和大小
公开(公告)号：US20140154703A1
公开(公告)日：2014-06-05
申请号：US13978123
申请日：2012-01-06
申请人： Alison Skelley , Denis Smirnov , Yi Dong , Keith D. Merdek , Kam Sprott , Walter Carney , Chunsheng Jiang , Richard Huang , Ioana Lupascu
发明人： Alison Skelley , Denis Smirnov , Yi Dong , Keith D. Merdek , Kam Sprott , Walter Carney , Chunsheng Jiang , Richard Huang , Ioana Lupascu
IPC分类号： G01N33/574
CPC分类号： G01N33/574 , B01L3/502761 , B01L2200/0652 , B01L2200/0668 , B01L2300/0822 , B01L2300/0877 , B01L2300/168 , B01L2400/086 , G01N30/6095
摘要： The invention encompasses methods and devices for diagnosing, theranosing, or prognosing a condition in a patient by enriching a sample in rare cells or other particles. The devices can be a microfluidic device comprising an array of obstacles and one or more binding moieties. The devices and methods can allow for enrichment of cells based on size and affinity, recovery of cells or other particles in locations on the microfluidic device, release of cells or other particles from the microfluidic device, flow of sample through the microfluidic device, and retention of rare cells or other particles from a sample obtained from a patient having a condition.
摘要翻译：本发明包括通过在罕见细胞或其他颗粒中富集样品来诊断，鉴别或预测病人状况的方法和装置。装置可以是包含障碍物阵列和一个或多个结合部分的微流体装置。所述装置和方法可以允许基于大小和亲和力富集细胞，在微流体装置上的位置中回收细胞或其它颗粒，从微流体装置释放细胞或其它颗粒，通过微流体装置的样品流动和保留从具有条件的患者获得的样品中的稀有细胞或其他颗粒。

8. 发明申请

US20140319529A1 ANTI-DIFFUSION LAYER, PREPARATION METHOD THEREOF, THIN-FILM TRANSISTOR (TFT), ARRAY SUBSTRATE, DISPLAY DEVICE 有权
标题翻译：抗扩散层，其制备方法，薄膜晶体管（TFT），阵列基板，显示器件
公开(公告)号：US20140319529A1
公开(公告)日：2014-10-30
申请号：US14345607
申请日：2013-05-31
申请人： Chunsheng Jiang , Haijing Chen , Dongfang Wang
发明人： Chunsheng Jiang , Haijing Chen , Dongfang Wang
IPC分类号： H01L21/288 , H01L21/02 , H01L27/12 , H01L29/51 , H01L29/49
CPC分类号： H01L21/2885 , C25D9/06 , H01L21/02183 , H01L21/02258 , H01L27/1237 , H01L27/1292 , H01L29/4908 , H01L29/517
摘要： An anti-diffusion layer, a preparation method thereof, a thin-film transistor (TFT), an array substrate and a display device are provided, involve the display device manufacturing field and can resolve problem that a high atmosphere temperature is need in process of preparing a tantalum dioxide anti-diffusion layer by PVD or CVD, which causes the gate electrode to volatilize and affect the performance of a display device. The method for preparing the anti-diffusion layer comprises: placing a conductive base (1) and a cathode (4) in a tantalum sulfate solution (3), taking the conductive base (1) as an anode, and forming a tantalum dioxide anti-diffusion layer on the conductive base (1) after energizing.
摘要翻译：提供了抗扩散层，其制备方法，薄膜晶体管（TFT），阵列基板和显示装置，涉及显示装置制造领域，并且可以解决在高温气氛中需要高气氛的问题通过PVD或CVD制备二氧化钽防扩散层，这导致栅电极挥发并影响显示装置的性能。制备抗扩散层的方法包括：以导电性基体（1）为阳极，将导电性基体（1）和阴极（4）置于硫酸钽溶液（3）中，形成二氧化钽通电后导电基体（1）上的扩散层。

9. 发明申请

US20070147705A1 Methods and systems for correcting image misalignment 有权
标题翻译：用于校正图像未对准的方法和系统
公开(公告)号：US20070147705A1
公开(公告)日：2007-06-28
申请号：US11633677
申请日：2006-12-04
申请人： Thomas Clune , Philippe Schmid , Chunsheng Jiang
发明人： Thomas Clune , Philippe Schmid , Chunsheng Jiang
IPC分类号： G06K9/32
CPC分类号： A61B1/00009 , A61B1/0008 , A61B1/00142 , A61B1/043 , A61B5/0071 , A61B5/0084 , A61B5/7257 , A61M11/00 , G06T7/262 , G06T7/37 , G06T2207/10068 , G06T2207/20056 , G06T2207/30004
摘要： The invention provides methods of determining a correction for a misalignment between at least two images in a sequence of images due at least in part to sample movement. The methods are applied, for example, in the processing and analysis of a sequence of images of biological tissue in a diagnostic procedure. The invention also provides methods of validating the correction for a misalignment between at least two images in a sequence of images of a sample. The methods may be applied in deciding whether a correction for misalignment accurately accounts for sample motion.
摘要翻译：本发明提供了至少部分地由于样品运动而确定图像序列中的至少两个图像之间的未对准的校正的方法。该方法例如用于在诊断程序中处理和分析生物组织的图像序列。本发明还提供验证样品图像序列中的至少两个图像之间的未对准的校正的方法。这些方法可以用于确定误差校正是否准确地考虑样品运动。

10. 发明授权

US06775399B1 ROI segmentation image processing system 失效
标题翻译： ROI分割图像处理系统
公开(公告)号：US06775399B1
公开(公告)日：2004-08-10
申请号：US09715889
申请日：2000-11-17
申请人： Chunsheng Jiang
发明人： Chunsheng Jiang
IPC分类号： G06K900
CPC分类号： G06T5/005 , G06T5/30 , G06T7/12 , G06T7/136 , G06T7/155 , G06T2207/10116 , G06T2207/20008 , G06T2207/20021 , G06T2207/20061 , G06T2207/20068 , G06T2207/30004
摘要： An improved ROI segmentation image processing system substantially masks non-ROI image data from a digital image to produce a ROI segmented image for subsequent digital processing. The ROI segmentation image processing system is a computer-based system having a collimation subsystem configured to detect and mask out collimated regions within the image. Furthermore, a direct exposure (DE) subsystem is configured to detect and remove DE regions from the image. Holes generated in the image are filled-in to provide a resulting image with only ROI.
摘要翻译：改进的ROI分割图像处理系统基本上从数字图像掩蔽非ROI图像数据，以产生用于后续数字处理的ROI分割图像。 ROI分割图像处理系统是基于计算机的系统，其具有被配置为检测和遮蔽图像内的准直区域的准直子系统。此外，直接曝光（DE）子系统被配置为从图像中检测和去除DE区域。图像中生成的孔被填充以提供仅具有ROI的结果图像。

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