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1. 发明授权

US09083067B2 Coaxial conductor structure 有权
标题翻译：同轴导体结构
公开(公告)号：US09083067B2
公开(公告)日：2015-07-14
申请号：US13635114
申请日：2011-03-29
申请人： Christoph Neumaier , Martin Lorenz , Natalie Spaeth , Kai Numssen , Josef Kreuzmair
发明人： Christoph Neumaier , Martin Lorenz , Natalie Spaeth , Kai Numssen , Josef Kreuzmair
IPC分类号： H01P3/06 , H01P1/16
CPC分类号： H01P1/16 , H01P3/06
摘要： A coaxial conductor structure for the interference-free transmission of a propagable TEM mode of an HF signal wave within at least one band of n frequency bands forming within a dispersion relation.
摘要翻译：一种同轴导体结构，用于在分散关系内形成的n个频带的至少一个带内的HF信号波的可传播TEM模式的无干扰传输。

2. 发明申请

US20130015927A1 COAXIAL CONDUCTOR STRUCTURE 有权
标题翻译：同轴导体结构
公开(公告)号：US20130015927A1
公开(公告)日：2013-01-17
申请号：US13635114
申请日：2011-03-29
申请人： Christoph Neumaier , Martin Lorenz , Natalie Spaeth , Kai Numssen , Josef Kreuzmair
发明人： Christoph Neumaier , Martin Lorenz , Natalie Spaeth , Kai Numssen , Josef Kreuzmair
IPC分类号： H01P3/06
CPC分类号： H01P1/16 , H01P3/06
摘要： A coaxial conductor structure for the interference-free transmission of a propagable TEM mode of an HF signal wave within at least one band of n frequency bands forming within a dispersion relation.
摘要翻译：一种同轴导体结构，用于在分散关系内形成的n个频带的至少一个带内的HF信号波的可传播TEM模式的无干扰传输。

3. 发明授权

US09312051B2 Coaxial conductor structure 有权
标题翻译：同轴导体结构
公开(公告)号：US09312051B2
公开(公告)日：2016-04-12
申请号：US13809901
申请日：2011-07-11
申请人： Martin Lorenz , Kai Numssen , Christoph Neumaier , Natalie Spaeth
发明人： Martin Lorenz , Kai Numssen , Christoph Neumaier , Natalie Spaeth
IPC分类号： H01B11/18 , H01P1/202
CPC分类号： H01B11/1808 , H01P1/202
摘要： The invention is a coaxial conductor structure for fault-free transmission of a TEM Mode of a HF signal wave within at least one band of frequency bands forming in the context of a dispersion relation. An inner conductor and an outer conductor are spaced radially apart from the inner conductor and an axially extending common conductor section of the inner and the outer conductor. A number n of electrically conductive ring-shaped structures are each fitted between the inner and outer conductor to be radially spaced apart, each of which have an electrical path completely surrounding the inner conductor and are arranged with a spatially periodic sequence with an equal distance between the two ring-shaped structures which are adjacent along the conductor section.
摘要翻译：本发明是一种同轴导体结构，用于在分散关系的上下文中形成的频带的至少一个频带内的HF信号波的TEM模式的无故障传输。内部导体和外部导体与内部导体和内部和外部导体的轴向延伸的公共导体部分径向间隔开。每个导体环状结构的数个n均配置在径向间隔开的内外导体之间，每个导电环形结构具有完全围绕内导体的电气路径，并且布置有空间周期性的序列，沿着导体部分相邻的两个环形结构。

4. 发明申请

US20130112477A1 COAXIAL CONDUCTOR STRUCTURE 有权
标题翻译：同轴导体结构
公开(公告)号：US20130112477A1
公开(公告)日：2013-05-09
申请号：US13809901
申请日：2011-07-11
申请人： Martin Lorenz , Kai Numssen , Christoph Neumaier , Natalie Spaeth
发明人： Martin Lorenz , Kai Numssen , Christoph Neumaier , Natalie Spaeth
IPC分类号： H01B11/18
CPC分类号： H01B11/1808 , H01P1/202
摘要： The invention is a coaxial conductor structure for fault-free transmission of a TEM Mode of a HF signal wave within at least one band of frequency bands forming in the context of a dispersion relation. An inner conductor and an outer conductor are spaced radially apart from the inner conductor and an axially extending common conductor section of the inner and the outer conductor. A number n of electrically conductive ring-shaped structures are each fitted between the inner and outer conductor to be radially spaced apart, each of which have an electrical path completely surrounding the inner conductor and are arranged with a spatially periodic sequence with an equal distance between the two ring-shaped structures which are adjacent along the conductor section.
摘要翻译：本发明是一种同轴导体结构，用于在分散关系的上下文中形成的频带的至少一个频带内的HF信号波的TEM模式的无故障传输。内部导体和外部导体与内部导体和内部和外部导体的轴向延伸的公共导体部分径向间隔开。每个导体环状结构的数个n均配置在径向间隔开的内外导体之间，每个导电环形结构具有完全围绕内导体的电气路径，并且布置有空间周期性的序列，沿着导体部分相邻的两个环形结构。

5. 发明授权

US5707099A Wind net for a convertible rollover bar 失效
标题翻译：可转换翻转杆的风网
公开(公告)号：US5707099A
公开(公告)日：1998-01-13
申请号：US718936
申请日：1996-09-24
申请人： Jurgen Schrader , Martin Lorenz , Stephan Orth
发明人： Jurgen Schrader , Martin Lorenz , Stephan Orth
IPC分类号： B60J7/22 , B60N2/90 , B62D35/00
CPC分类号： B60N2/44 , B60J7/223
摘要： On the cross traverse of at least one convertible automobile rollover bar, a wind net is supported on a span at least approximately the surface between the lateral members of the rollover bar. The upper edge of the wind net rests on an exterior side of the cross traverse in a tensioned manner, and the wind net itself extends down only to approximately the level of the vehicle edge.
摘要翻译：在至少一个可转换的汽车翻车杆的横向横移上，风网至少在翻转杆的横向构件之间的表面上支撑在跨距上。风网的上边缘以张紧的方式搁置在横向横移的外侧上，并且风网本身仅向下延伸到车辆边缘的大致水平。

6. 发明授权

US08143242B2 Malonamide derivatives with antithrombotic activity 有权
标题翻译：具有抗血栓活性的丙二酰胺衍生物
公开(公告)号：US08143242B2
公开(公告)日：2012-03-27
申请号：US12683736
申请日：2010-01-07
申请人： Henning Steinhagen , Hauke Szillat , Markus Follmann , Reinhard Kirsch , Volkmar Wehner , Hans Matter , Martin Lorenz , Kent W. Neuenschwander , Anthony C. Scotese
发明人： Henning Steinhagen , Hauke Szillat , Markus Follmann , Reinhard Kirsch , Volkmar Wehner , Hans Matter , Martin Lorenz , Kent W. Neuenschwander , Anthony C. Scotese
IPC分类号： A61K31/553 , A61K31/4965 , A61K31/44 , A61K31/426 , A61K31/381 , A61K31/167 , C07D281/06 , C07D241/04 , C07D213/65 , C07D277/24 , C07D409/02 , C07C237/20
CPC分类号： C07D213/80 , C07C257/18 , C07C311/08 , C07C311/46 , C07C317/22 , C07C317/32 , C07C2601/14 , C07D211/42 , C07D213/30 , C07D213/34 , C07D309/08 , C07D409/12 , C07D413/12
摘要： The present invention relates to compounds of formula I, The compounds of formula I are valuable pharmacologically active compounds. They exhibit a strong anti-thrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardio-vascular disorders like thromboembolic diseases or restenoses. They are inhibitors of the blood clotting enzymes, especially factor VIIa and can in general be applied in conditions in which an undesired activity of factor VIIa is present or for the cure or prevention of which an inhibition of factor VIIa is intended. The invention furthermore relates to processes for the preparation of compounds of formula I, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.
摘要翻译：本发明涉及式I化合物。式I化合物是有价值的药理学活性化合物。它们表现出强烈的抗血栓形成作用，并且适用于治疗和预防心血管疾病如血栓栓塞性疾病或再狭窄。它们是血液凝固酶，特别是因子VIIa的抑制剂，并且通常可用于其中存在不需要的因子VIIa的活性或用于治疗或预防因子VIIa的抑制的条件。本发明还涉及制备式I化合物的方法，其用途，特别是作为药物中的活性成分，以及包含它们的药物制剂。

7. 发明授权

US08852593B2 Antagonist antibodies and their fab fragments against GPVI and uses thereof 有权
标题翻译：拮抗剂抗体及其针对GPVI的Fab片段及其用途
公开(公告)号：US08852593B2
公开(公告)日：2014-10-07
申请号：US13515650
申请日：2010-12-17
申请人： Nicolas Baurin , Francis Blanche , Beatrice Cameron , Carsten Corvey , Tarik Dabdoubi , Christian Engel , Peter Florian , Ingo Focken , Katja Kroll , Jochen Kruip , Christian Lange , Thomas Langer , Martin Lorenz , Vincent Mikol , Ercole Rao , Peter Wonerow
发明人： Nicolas Baurin , Francis Blanche , Beatrice Cameron , Carsten Corvey , Tarik Dabdoubi , Christian Engel , Peter Florian , Ingo Focken , Katja Kroll , Jochen Kruip , Christian Lange , Thomas Langer , Martin Lorenz , Vincent Mikol , Ercole Rao , Peter Wonerow
IPC分类号： A61K39/395 , C07K16/28 , A61K39/00
CPC分类号： C07K16/28 , A61K2039/505 , C07K1/1075 , C07K16/2803 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
摘要： The present invention discloses novel antibodies that specifically bind to the human platelet membrane protein Glycoprotein VI (GPVI) and their monovalent fragments or derivatives. The antibodies of the invention are antibodies from hybridoma clone 390 and fragment antibodies thereof able to induce a GPVI depletion phenotype. These antibodies and Fab fragments are able to block collagen binding and thus preventing platelet activation by collagen. The invention also relates to hybridoma clones and expression plasmids for the production of disclosed antibodies and Fab fragments. The present invention further refers to the uses of monovalent antibody fragments to manufacture research, diagnostic and immunotherapeutic agents for the treatment of thrombosis and other vascular diseases. The invention also concerns a Fab bearing a molecule at the C-terminal extremity, as well as method for prevention of recognition of Fab by antibodies using such modified Fab. The invention concerns a method for prevention of platelet activation when an anti-GP VI Fab is used.
摘要翻译：本发明公开了特异性结合人血小板膜蛋白Glycoprotein VI（GPVI）及其单价片段或衍生物的新型抗体。本发明的抗体是来自杂交瘤克隆390的抗体及其能诱导GPVI消耗表型的片段抗体。这些抗体和Fab片段能够阻断胶原结合，从而阻止胶原的血小板活化。本发明还涉及用于产生所公开的抗体和Fab片段的杂交瘤克隆和表达质粒。本发明还涉及一价抗体片段用于制备用于治疗血栓形成和其它血管疾病的研究，诊断和免疫治疗剂的用途。本发明还涉及在C-末端具有分子的Fab，以及使用这种修饰的Fab预防用抗体识别Fab的方法。本发明涉及当使用抗GP VI Fab时预防血小板活化的方法。

8. 发明授权

US08088925B2 Heteroaryl-carboxylic acid (sulfamoyl alkyl) amide-derivatives as factor Xa inhibitors 有权
标题翻译：杂芳基羧酸（氨磺酰基烷基）酰胺衍生物作为因子Xa抑制剂
公开(公告)号：US08088925B2
公开(公告)日：2012-01-03
申请号：US11940654
申请日：2007-11-15
申请人： Michael Wagner , Matthias Urmann , Volkmar Wehner , Martin Lorenz , Armin Bauer , Marc Nazare , Hans Matter
发明人： Michael Wagner , Matthias Urmann , Volkmar Wehner , Martin Lorenz , Armin Bauer , Marc Nazare , Hans Matter
IPC分类号： C07D401/02 , C07D403/02 , C07D333/10 , C07D333/28 , A61K31/4535 , A61K31/381 , A61K31/497
CPC分类号： C07D211/58 , C07D333/38 , C07D401/12 , C07D405/12 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/14 , C07D419/14
摘要： The present invention relates to compounds of the formula I, which exhibit a strong antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardiovascular disorders like thromboembolic diseases or restenoses.
摘要翻译：本发明涉及式I化合物，其具有强的抗血栓形成作用，并且适用于治疗和预防心血管疾病如血栓栓塞性疾病或再狭窄。

9. 发明申请

US20120244152A1 NOVEL ANTAGONIST ANTIBODIES AND THEIR FAB FRAGMENTS AGAINST GPVI AND USES THEREOF 有权
标题翻译：新型拮抗剂抗体及其抗GPVI及其用途的FAB片段
公开(公告)号：US20120244152A1
公开(公告)日：2012-09-27
申请号：US13515650
申请日：2010-12-17
申请人： Nicolas Baurin , Francis Blanche , Beatrice Cameron , Carsten Corvey , Tarik Dabdoubi , Christian Engel , Peter Florian , Ingo Focken , Katja Kroll , Jochen Kruip , Christian Lange , Thomas Langer , Martin Lorenz , Vincent Mikol , Ercole Rao , Peter Wonerow
发明人： Nicolas Baurin , Francis Blanche , Beatrice Cameron , Carsten Corvey , Tarik Dabdoubi , Christian Engel , Peter Florian , Ingo Focken , Katja Kroll , Jochen Kruip , Christian Lange , Thomas Langer , Martin Lorenz , Vincent Mikol , Ercole Rao , Peter Wonerow
IPC分类号： A61K39/395 , C07K16/28 , A61P9/00 , C12P21/02 , A61P7/02 , C07K1/00 , C12N15/13
CPC分类号： C07K16/28 , A61K2039/505 , C07K1/1075 , C07K16/2803 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
摘要： The present invention discloses novel antibodies that specifically bind to the human platelet membrane protein Glycoprotein VI (GPVI) and their monovalent fragments or derivatives. The antibodies of the invention are antibodies from hybridoma clone 390 and fragment antibodies thereof able to induce a GPVI depletion pheno-type. These antibodies and Fab fragments are able to block collagen binding and thus preventing platelet activation by collagen. The invention also relates to hybridoma clones and expression plasmids for the production of disclosed antibodies and Fab fragments. The present invention further refers to the uses of monovalent antibody fragments to manufacture research, diagnostic and immunotherapeutic agents for the treatment of thrombosis and other vascular diseases. The invention also concerns a Fab bearing a molecule at the C-terminal extremity, as well as method for prevention of recognition of Fab by antibodies using such modified Fab. The invention concerns a method for prevention of platelet activation when an anti-GP VI Fab is used.
摘要翻译：本发明公开了特异性结合人血小板膜蛋白Glycoprotein VI（GPVI）及其一价片段或衍生物的新型抗体。本发明的抗体是来自杂交瘤克隆390的抗体及其能诱导GPVI消耗物质型的片段抗体。这些抗体和Fab片段能够阻断胶原结合，从而阻止胶原的血小板活化。本发明还涉及用于产生所公开的抗体和Fab片段的杂交瘤克隆和表达质粒。本发明还涉及一价抗体片段用于制备用于治疗血栓形成和其它血管疾病的研究，诊断和免疫治疗剂的用途。本发明还涉及在C-末端具有分子的Fab，以及使用这种修饰的Fab预防用抗体识别Fab的方法。本发明涉及当使用抗GP VI Fab时预防血小板活化的方法。

10. 发明授权

US06123382A Swivel device for a rear window 失效
标题翻译：用于后窗的回转装置
公开(公告)号：US06123382A
公开(公告)日：2000-09-26
申请号：US201829
申请日：1998-12-01
申请人： Martin Lorenz
发明人： Martin Lorenz
IPC分类号： B60J1/18 , B60J1/10
CPC分类号： B60J1/1823
摘要： A vehicle has a folding roof extending between lateral vehicle columns, particularly A-columns and C-columns, a rear window and a vehicle body with a trunk. The rear window is releasably connected in its lower area by way of a swivel device with the vehicle body. The rear window can be deposited in the trunk by way of the swivel device. The rear window is connected by connection devices in its lateral area with the C-columns and/or in its upper area with the folding roof in a releasable manner. In the lower area of the rear window, a sealing device extending in the transverse direction of the vehicle is arranged between the rear window and the vehicle body. Between the lateral areas of the rear window and the C-columns and/or the upper area of the rear window and the folding roof, a sealing device is provided.
摘要翻译：车辆具有在侧车柱之间延伸的折叠屋顶，特别是A柱和C柱，后窗和具有行李箱的车体。后窗通过与车体的旋转装置可释放地连接在其下部区域中。后窗可以通过旋转装置沉积在躯干中。后窗通过其侧面区域的连接装置与C柱和/或其上部区域以可释放的方式与折叠屋顶连接。在后窗的下部区域，在后窗与车身之间配置有沿车辆的宽度方向延伸的密封装置。在后窗的侧面区域和C列和/或后窗的上部区域和折叠屋顶之间设置密封装置。

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