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1. 发明授权

US07986410B2 Method for detecting a fibrous web tear in a drying section of a machine for producing the fibrous web and apparatus for performing said method 失效
标题翻译：用于检测用于生产纤维幅材的机器的干燥部分中的纤维网撕裂的方法和用于执行所述方法的装置
公开(公告)号：US07986410B2
公开(公告)日：2011-07-26
申请号：US12050621
申请日：2008-03-18
申请人： Armin Bauer , Dietmar Üblacker
发明人： Armin Bauer , Dietmar Üblacker
IPC分类号： G01N21/84
CPC分类号： G01N21/8901 , D21F7/04 , D21G9/0036
摘要： This invention relates to a method for detecting a tear in a fibrous web in a drying section of a machine for producing the fibrous web, whereby the fibrous web is passed through the drying section by way of at least one dryer fabric, whereby the tear is detected by at least one optical web tear detection device, which includes at least one luminous source and one detector, and whereby a cut-off apparatus for the fibrous web is directly or indirectly activated by the web tear detection device. The optical web tear detection device is operated over an extended wave length range in order to detect a tear in the fibrous web reliably. In addition, the invention relates to an apparatus for performing the inventive method.
摘要翻译：本发明涉及一种用于检测用于生产纤维幅材的机器的干燥部分中的纤维幅材的撕裂的方法，由此纤维幅材通过至少一个干燥织物通过干燥部分，由此撕裂是由包括至少一个发光源和一个检测器的至少一个光学纤网撕裂检测装置检测到，并且由此纤维幅材的切断装置由卷材撕裂检测装置直接或间接地启动。光纤撕裂检测装置在延长的波长范围内操作，以便可靠地检测纤维幅材中的撕裂。此外，本发明涉及一种用于执行本发明的方法的装置。

2. 发明申请

US20080167346A1 HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS 有权
标题翻译：异硫氰酸（磺酰氨基）酰胺 - 衍生物作为因子XA抑制剂
公开(公告)号：US20080167346A1
公开(公告)日：2008-07-10
申请号：US11940654
申请日：2007-11-15
申请人： Michael WAGNER , Matthias URMANN , Volkmar WEHNER , Martin LORENZ , Armin BAUER , Marc NAZARE , Hans MATTER
发明人： Michael WAGNER , Matthias URMANN , Volkmar WEHNER , Martin LORENZ , Armin BAUER , Marc NAZARE , Hans MATTER
IPC分类号： A61K31/4535 , C07C233/57 , A61K31/166 , A61P11/00 , A61P9/00 , C07D409/12
CPC分类号： C07D211/58 , C07D333/38 , C07D401/12 , C07D405/12 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/14 , C07D419/14
摘要： The present invention relates to compounds of the formula I, which exhibit a strong antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardiovascular disorders like thromboembolic diseases or restenoses.
摘要翻译：本发明涉及式I化合物，其具有强的抗血栓形成作用，并且适用于治疗和预防心血管疾病如血栓栓塞性疾病或再狭窄。

3. 发明授权

US07358268B2 Imidazole derivatives as factor Xa inhibitors 有权
标题翻译：咪唑衍生物作为因子Xa抑制剂
公开(公告)号：US07358268B2
公开(公告)日：2008-04-15
申请号：US10728339
申请日：2003-12-04
申请人： Marc Nazare , Armin Bauer , Volkmar Wehner , David W. Will , Hans Matter , Michael Wagner , Herman Schreuder
发明人： Marc Nazare , Armin Bauer , Volkmar Wehner , David W. Will , Hans Matter , Michael Wagner , Herman Schreuder
IPC分类号： A61K31/42 , C07D261/04 , C07D413/04
CPC分类号： C07D401/12 , C07D401/14 , C07D413/14 , C07D417/14
摘要： This invention is directed to the compound of formula (I) which is useful for inhibiting the activity of Factor Xa. The present invention is also directed to compositions containing said compounds, processes for their preparation, their use, such as in inhibiting the formation of thrombin or for therapeutically or prophylactically treating a patient suffering from, or subject to, or associated with a disease state associated with a cardiovascular disorder.
摘要翻译：本发明涉及可用于抑制因子Xa的活性的式（I）化合物。本发明还涉及包含所述化合物的组合物，其制备方法，其用途，例如抑制凝血酶的形成或用于治疗或预防性地治疗患有或与疾病状态有关的患者或与之相关的患者伴有心血管疾病。

4. 发明申请

US20070179122A1 Beta-Aminoacid-Derivatives As Factor Xa Inhibitors 审中-公开
标题翻译： β-氨基酸衍生物作为因子Xa抑制剂
公开(公告)号：US20070179122A1
公开(公告)日：2007-08-02
申请号：US11469513
申请日：2006-09-01
申请人： Matthias Urmann , Marc Nazare , Volkmar Wehner , Hans Matter , Armin Bauer , Michael Wagner
发明人： Matthias Urmann , Marc Nazare , Volkmar Wehner , Hans Matter , Armin Bauer , Michael Wagner
IPC分类号： A61K31/553 , A61K31/551 , A61K31/55 , A61K31/541 , A61K31/496 , A61K31/5377 , C07D417/02 , C07D413/02 , C07D403/02
CPC分类号： C07K5/0202 , C07D265/32 , C07D265/33 , C07D291/06 , C07D295/112 , C07D409/12 , C07D409/14 , C07D413/12 , C07D419/12
摘要： The present invention relates to compounds of the formula I, in which R0; R1; R2; R3; R4; R5, R, Q; V, G and M have the meanings indicated in the claims. The compounds of the formula I are valuable pharmacologically active compounds. They exhibit a strong antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardiovascular disorders like thromboemboic diseases or restenoses. They are reversible inhibitors of the blood clotting enzymes factor Xa (FXa) and/or factor VIIa (FVIIa), and can in general be applied in conditions in which an undesired activity of factor Xa and/or factor VIIa is present or for the cure or prevention of which an inhibition of factor Xa and/or factor VIIa is intended. The invention furthermore relates to processes for the preparation of compounds of the formula I, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.
摘要翻译：本发明涉及式I化合物，其中R 0， R＆lt; 1＆gt;; R 2; 3＆lt; 3＆gt; R 4; R 5，R，Q; V，G和M具有权利要求中所示的含义。式I的化合物是有价值的药理活性化合物。它们表现出强烈的抗血栓形成作用，并且适用于例如治疗和预防心血管疾病如血栓栓塞性疾病或再狭窄。它们是血液凝固酶因子Xa（FXa）和/或因子VIIa（FVIIa）的可逆抑制剂，并且通常可用于存在因子Xa和/或因子VIIa的不期望活性或用于治愈或预防因子Xa和/或因子VIIa的抑制。本发明还涉及式I化合物的制备方法，其用途，特别是作为药物中的活性成分，以及包含它们的药物制剂。

5. 发明申请

US20090275523A1 Spirocyclic nitriles as protease inhibitors 有权
标题翻译：螺环腈作为蛋白酶抑制剂
公开(公告)号：US20090275523A1
公开(公告)日：2009-11-05
申请号：US12277880
申请日：2008-11-25
申请人： Manfred Schudok , Michael Wagner , Armin Bauer , Anna Kohlmann
发明人： Manfred Schudok , Michael Wagner , Armin Bauer , Anna Kohlmann
IPC分类号： A61K38/05 , C07D221/20 , C07D471/10 , C07C255/29 , C07D498/10 , A61P35/00
CPC分类号： C07D319/14 , C07C233/63 , C07C255/46 , C07C2601/02 , C07D211/66 , C07D213/26 , C07D221/20 , C07D231/54 , C07D263/52 , C07D295/215 , C07D295/26 , C07D317/72 , C07D471/10 , C07D491/10
摘要： The invention relates to substituted carbo- and heterocyclic spiro compounds of the formula Ia which inhibit thiol proteases, to processes for their preparation and to the use thereof as medicaments.
摘要翻译：本发明涉及抑制巯基蛋白酶的式Ia的取代的碳杂环和杂环螺环化合物，其制备方法及其作为药物的用途。

6. 发明授权

US07465806B2 Pyrrole-derivatives as factor Xa inhibitors 有权
标题翻译：吡咯衍生物作为因子Xa抑制剂
公开(公告)号：US07465806B2
公开(公告)日：2008-12-16
申请号：US11467277
申请日：2006-08-25
申请人： Armin Bauer , Michael Wagner , Marc Nazare , Volkmar Wehner , Matthias Urmann , Hans Matter
发明人： Armin Bauer , Michael Wagner , Marc Nazare , Volkmar Wehner , Matthias Urmann , Hans Matter
IPC分类号： C07D261/06 , C07D207/32
CPC分类号： C07D401/12 , C07D401/14 , C07D413/14
摘要： The present invention relates to compounds of the formulae I and Ia, wherein R0; R1; R3; R4; R22, Q; V, G and M have the meanings indicated in the claims. The compounds of the formulae I and Ia are valuable pharmacologically active compounds. They exhibit a strong antithrombotic effect and are suitable for the therapy and prophylaxis of cardiovascular disorders like thromboembolic diseases or restenoses. They are reversible inhibitors of the blood clotting enzymes factor Xa (FXa) and/or factor VIIa (FVIIa), and can in general be applied in conditions in which an undesired activity of factor Xa and/or factor VIIa is present or for the cure or prevention of which an inhibition of factor Xa and/or factor VIIa is intended. The invention furthermore relates to processes for the preparation of compounds of the formulae I and Ia, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.
摘要翻译：本发明涉及式I和Ia的化合物，其中R 0; R1; R3; R4; R22，Q; V，G和M具有权利要求中所示的含义。式I和Ia的化合物是有价值的药理活性化合物。它们具有强烈的抗血栓形成作用，适用于治疗和预防心血管疾病如血栓栓塞性疾病或再狭窄。它们是血液凝固酶因子Xa（FXa）和/或因子VIIa（FVIIa）的可逆抑制剂，并且通常可用于存在因子Xa和/或因子VIIa的不期望活性或用于治愈或预防因子Xa和/或因子VIIa的抑制。本发明还涉及制备式I和Ia化合物的方法，其用途，特别是作为药物中的活性成分，以及包含它们的药物制剂。

7. 发明授权

US06900233B2 Substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadiazol-2-ones, pharmaceutical composition and method for treating obesity thereof 有权
标题翻译：取代的3-苯基-5-烷氧基-3H-（1,3,4） - 恶二唑-2-酮药物组合物及其肥胖症的治疗方法
公开(公告)号：US06900233B2
公开(公告)日：2005-05-31
申请号：US10375247
申请日：2003-02-27
申请人： Karl Schoenafinger , Stefan Petry , Günter Müller , Armin Bauer , Hubert Otto Heuer
发明人： Karl Schoenafinger , Stefan Petry , Günter Müller , Armin Bauer , Hubert Otto Heuer
IPC分类号： C07D271/10 , C07D271/113 , A61K31/4245 , A61P3/00
CPC分类号： C07D271/113
摘要： A substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadiazol-2-one, compound of formula 1, wherein R1, R2, R3, R4 and R5 are as defined herein, pharmaceutical composition comprising the compound and use of the compound for inhibiting pancreatic lipase, or the prophylaxis or treatment of obesity are described.
摘要翻译：取代的3-苯基-5-烷氧基-3H-（1,3,4） - 恶二唑-2-酮，式1的化合物，其中R 1，R 2， >，R 3，R 4和R 5如本文所定义，包含该化合物的药物组合物和用于抑制胰脂肪酶的化合物，或预防或治疗肥胖症。

8. 发明授权

US5969145A Process for the production of epothilones and intermediate products within the process 失效
标题翻译：在过程中生产埃坡霉素和中间产物的方法
公开(公告)号：US5969145A
公开(公告)日：1999-10-19
申请号：US921512
申请日：1997-09-02
申请人： Dieter Schinzer , Anja Limberg , Oliver M. Bohm , Armin Bauer , Martin Cordes
发明人： Dieter Schinzer , Anja Limberg , Oliver M. Bohm , Armin Bauer , Martin Cordes
IPC分类号： C07D277/22 , C07D277/24 , C07D277/30 , C07D319/06 , C07D493/04 , C07F7/18
CPC分类号： C07D493/04 , C07D277/24 , C07D319/06 , C07F7/1852 , C07F7/1856
摘要： The invention relates to a process for the production of epothilones and intermediate products within the process.Epothilones A and B are natural substances, which can be produced by microorganisms, and the taxols have similar properties and are thus of particular interest in pharmaceutical chemistry.
摘要翻译：本发明涉及在该方法中生产埃坡霉素和中间产物的方法。埃坡霉素A和B是天然物质，其可以由微生物产生，并且所述紫杉醇具有相似的性质，因此在药物化学中特别感兴趣。

9. 发明申请

US20090237664A1 METHOD FOR DETECTING A FIBROUS WEB TEAR IN A DRYING SECTION OF A MACHINE FOR PRODUCING THE FIBROUS WEB AND APPARATUS FOR PERFORMING SAID METHOD 失效
标题翻译：用于检测用于生产纤维网的机器的干燥部分中的纤维网络的方法和用于执行所述方法的装置
公开(公告)号：US20090237664A1
公开(公告)日：2009-09-24
申请号：US12050621
申请日：2008-03-18
申请人： Armin Bauer , Dietmar Ublacker
发明人： Armin Bauer , Dietmar Ublacker
IPC分类号： G01N21/84
CPC分类号： G01N21/8901 , D21F7/04 , D21G9/0036
摘要： This invention relates to a method for detecting a tear in a fibrous web in a drying section of a machine for producing the fibrous web, whereby the fibrous web is passed through the drying section by way of at least one dryer fabric, whereby the tear is detected by at least one optical web tear detection device, which includes at least one luminous source and one detector, and whereby a cut-off apparatus for the fibrous web is directly or indirectly activated by the web tear detection device. The optical web tear detection device is operated over an extended wave length range in order to detect a tear in the fibrous web reliably. In addition, the invention relates to an apparatus for performing the inventive method.
摘要翻译：本发明涉及一种用于检测用于生产纤维幅材的机器的干燥部分中的纤维幅材的撕裂的方法，由此纤维幅材通过至少一个干燥织物通过干燥部分，由此撕裂是由包括至少一个发光源和一个检测器的至少一个光学纤网撕裂检测装置检测到，并且由此纤维幅材的切断装置由卷材撕裂检测装置直接或间接地启动。光纤撕裂检测装置在延长的波长范围内操作，以便可靠地检测纤维幅材中的撕裂。此外，本发明涉及一种用于执行本发明的方法的装置。

10. 发明申请

US20090220146A1 METHOD AND APPARATUS FOR CHARACTERIZING THE FORMATION OF PAPER 审中-公开
标题翻译：用于表征纸张形成的方法和装置
公开(公告)号：US20090220146A1
公开(公告)日：2009-09-03
申请号：US12394597
申请日：2009-02-27
申请人： Armin Bauer , Marianne Kiniger
发明人： Armin Bauer , Marianne Kiniger
IPC分类号： G06K9/66
CPC分类号： G06K9/46 , G06K9/00577 , G06T7/44 , G06T2207/20076 , G06T2207/20081 , G06T2207/30124
摘要： A method for characterizing the formation of paper in which patterns and/or structures existing in the paper are automatically characterized and classified. The automatic characterization and classification includes creating a collection of paper specimens, creating a digital image of each individual specimen, digital pre-processing of the digital image where necessary, calculating different multi-dimensional features in light of the digital images or sub-ranges of the images, analyzing structure-specific groups forming in the feature space during calculation of the different multi-dimensional features and analyzing the structure-specific groups in the feature space, projecting the results of the analysis of the structure-specific groups into a—compared to the feature space—low-dimensional space for visualizing the analysis results, and drawing on the analysis results for the classification of newly added specimens. The calculation of the different multi-dimensional features takes place in light of the digital images or sub-ranges of the images on the basis of at least one of the following algorithms: relational kernel function (RKF), phase-based method, 2-point or 3-point method, or wavelets.
摘要翻译：用于表征纸张形成的方法，其中纸张中存在的图案和/或结构被自动表征和分类。自动表征和分类包括创建纸样的集合，创建每个单独样本的数字图像，在必要时数字图像的数字预处理，根据数字图像或子范围的子范围计算不同的多维特征在不同多维特征的计算过程中分析特征空间组成特征，并分析特征空间中的结构特定群体，将结构特定群体的分析结果投入比较到特征空间 - 低维空间，用于可视化分析结果，并利用新添加样本分类的分析结果。根据以下算法中的至少一种算法，根据图像的数字图像或子范围进行不同多维特征的计算：关系核函数（RKF），基于相位的方法，点或3点法，或小波。

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