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1. 发明授权

US08049873B2 Surgical microscopy system having an optical coherence tomography facility 有权
标题翻译：具有光学相干断层摄影设备的手术显微镜系统
公开(公告)号：US08049873B2
公开(公告)日：2011-11-01
申请号：US12406671
申请日：2009-03-18
申请人： Christoph Hauger , Markus Seesselberg , Keith O'Hara , Yue Qiu , Xing Wei , Jochen M. Horn , Peter Reimer
发明人： Christoph Hauger , Markus Seesselberg , Keith O'Hara , Yue Qiu , Xing Wei , Jochen M. Horn , Peter Reimer
IPC分类号： G01B11/02 , G01N21/00
CPC分类号： G02B21/22 , A61B3/102 , A61B3/13 , A61B90/20 , G01N21/4795 , G02B21/0012 , G02B21/082
摘要： A surgical microscopy system is provided wherein an optical coherence tomography facility is integrated into a microscopy system. A beam of measuring light formed by collimating optics of an OCT system is deflected by a beam scanner, traverses imaging optics, and is reflected by a reflector such that the beam of measuring light traverses an objective lens of microscopy optics and is directed to an object region of the microscopy optics. A position of the beam of measuring light being incident on the reflector is substantially independent on a direction into which the beam of measuring light is deflected by the beam scanner. When traveling through the beam scanner, the beam of measuring light is comprised of a bundle of substantially parallel light rays.
摘要翻译：提供了一种外科显微镜系统，其中将光学相干断层摄影装置整合到显微镜系统中。通过OCT系统的准直光学器件形成的测量光束被光束扫描仪偏转，穿过成像光学元件，并被反射器反射，使得测量光束横穿显微镜光学元件的物镜并被引导到物体显微镜光学领域。入射到反射器上的测量光束的位置基本上独立于光束扫描器偏转的测量光束的方向。当通过光束扫描器行进时，测量光束由一束基本上平行的光线组成。

2. 发明申请

US20090257065A1 SURGICAL MICROSCOPY SYSTEM HAVING AN OPTICAL COHERENCE TOMOGRAPHY FACILITY 有权
标题翻译：具有光学相干性成像设备的手术显微镜系统
公开(公告)号：US20090257065A1
公开(公告)日：2009-10-15
申请号：US12406671
申请日：2009-03-18
申请人： Christoph Hauger , Markus Seesselberg , Keith O'Hara , Yue Qiu , Xing Wei , Jochen M. Horn , Peter Reimer
发明人： Christoph Hauger , Markus Seesselberg , Keith O'Hara , Yue Qiu , Xing Wei , Jochen M. Horn , Peter Reimer
IPC分类号： G01B9/02
CPC分类号： G02B21/22 , A61B3/102 , A61B3/13 , A61B90/20 , G01N21/4795 , G02B21/0012 , G02B21/082
摘要： A surgical microscopy system is provided wherein an optical coherence tomography facility is integrated into a microscopy system. A beam of measuring light formed by collimating optics of an OCT system is deflected by a beam scanner, traverses imaging optics, and is reflected by a reflector such that the beam of measuring light traverses an objective lens of microscopy optics and is directed to an object region of the microscopy optics. A position of the beam of measuring light being incident on the reflector is substantially independent on a direction into which the beam of measuring light is deflected by the beam scanner. When traveling through the beam scanner, the beam of measuring light is comprised of a bundle of substantially parallel light rays.
摘要翻译：提供了一种外科显微镜系统，其中将光学相干断层摄影装置整合到显微镜系统中。通过OCT系统的准直光学器件形成的测量光束被光束扫描仪偏转，穿过成像光学元件，并被反射器反射，使得测量光束横穿显微镜光学元件的物镜并被引导到物体显微镜光学领域。入射到反射器上的测量光束的位置基本上独立于光束扫描器偏转的测量光束的方向。当通过光束扫描器行进时，测量光束由一束基本平行的光线组成。

3. 发明授权

US08922882B2 Imaging system 有权
标题翻译：成像系统
公开(公告)号：US08922882B2
公开(公告)日：2014-12-30
申请号：US13116358
申请日：2011-05-26
申请人： Christoph Hauger , Markus Seesselberg , Martin Hacker , Keith O'Hara
发明人： Christoph Hauger , Markus Seesselberg , Martin Hacker , Keith O'Hara
IPC分类号： G02B23/12 , G02B21/06 , G01B9/02 , G01J3/45 , A61B3/10 , A61B3/13
CPC分类号： A61B3/102 , A61B3/005 , A61B3/117 , A61B3/12 , A61B3/1225 , A61B3/13 , A61B3/14 , G01B9/02004 , G01B9/0203 , G01B9/02035 , G01B9/02044 , G01B9/02091 , G02B7/14 , G02B27/0955
摘要： Imaging systems are provided allowing examination of different object regions spaced apart in a depth direction by visual microscopy and by optical coherence tomography. An axial field of view and a lateral resolution is varied depending on which object region is examined by the imaging system. The proposed imaging systems are in particular applicable for thorough examination of the human eye.
摘要翻译：提供成像系统，允许通过视觉显微镜和光学相干断层摄影检查在深度方向上间隔开的不同物体区域。取决于由成像系统检查的对象区域来改变轴向视场和横向分辨率。所提出的成像系统特别适用于人眼的彻底检查。

4. 发明申请

US20110228218A1 IMAGING SYSTEM 有权
标题翻译：成像系统
公开(公告)号：US20110228218A1
公开(公告)日：2011-09-22
申请号：US13116358
申请日：2011-05-26
申请人： Christoph Hauger , Markus Seesselberg , Martin Hacker , Keith O'Hara
发明人： Christoph Hauger , Markus Seesselberg , Martin Hacker , Keith O'Hara
IPC分类号： A61B3/18 , G01B9/02 , A61B3/13
CPC分类号： A61B3/102 , A61B3/005 , A61B3/117 , A61B3/12 , A61B3/1225 , A61B3/13 , A61B3/14 , G01B9/02004 , G01B9/0203 , G01B9/02035 , G01B9/02044 , G01B9/02091 , G02B7/14 , G02B27/0955
摘要： Imaging systems are provided allowing examination of different object regions spaced apart in a depth direction by visual microscopy and by optical coherence tomography. An axial field of view and a lateral resolution is varied depending on which object region is examined by the imaging system. The proposed imaging systems are in particular applicable for thorough examination of the human eye.
摘要翻译：提供成像系统，允许通过视觉显微镜和光学相干断层摄影检查在深度方向上间隔开的不同物体区域。取决于由成像系统检查的对象区域来改变轴向视场和横向分辨率。所提出的成像系统特别适用于人眼的彻底检查。

5. 发明授权

US08427653B2 Optical coherence tomography methods and systems 有权
标题翻译：光学相干断层扫描方法和系统
公开(公告)号：US08427653B2
公开(公告)日：2013-04-23
申请号：US13007470
申请日：2011-01-14
申请人： Martin Hacker , Christoph Hauger , Keith O'Hara , Scott Meyer
发明人： Martin Hacker , Christoph Hauger , Keith O'Hara , Scott Meyer
IPC分类号： G01B11/02
CPC分类号： A61B3/102 , A61B3/1225 , A61B5/0066 , A61B5/0073 , G01B9/02004 , G01B9/02007 , G01B9/02009 , G01B9/02044 , G01B9/02091 , G01N21/4795
摘要： Frequency domain optical coherence tomography (FD-OCT) systems and methods are provided. Thereby, a first measurement and a second measurement is performed, wherein in the first measurement an object region is illuminated by measuring light having a spectrum with a first spectral width and in the second measurement the object region is illuminated with measuring light having a spectrum with a second spectral width, wherein the first spectral width is at least 10% greater than the second spectral width. Further, during the first measurement intensities of spectral ranges of light having interacted with the object and being superimposed with reference light are detected, wherein a width of these spectral ranges is greater than a corresponding width during the second measurement. Thus, switching an axial field of view of structural information of the object across a depth direction is enabled upon minimizing radiation damage at the object.
摘要翻译：提供了频域光学相干断层扫描（FD-OCT）系统和方法。由此，执行第一测量和第二测量，其中在第一测量中，通过测量具有第一光谱宽度的光谱的光照射对象区域，并且在第二测量中，用具有光谱的测量光照射对象区域第二光谱宽度，其中所述第一光谱宽度比所述第二光谱宽度大至少10％。此外，在第一测量期间，检测到与对象相互作用并与参考光叠加的光的光谱范围的强度，其中这些光谱范围的宽度大于第二测量期间的对应宽度。因此，在最小化物体的辐射损伤的情况下，能够在深度方向上切换物体的结构信息的轴向视场。

6. 发明授权

US07456957B2 Littrow spectrometer and a spectral domain optical coherence tomography system with a Littrow spectrometer 有权
标题翻译： Littrow光谱仪和具有Littrow光谱仪的光谱域光学相干断层扫描系统
公开(公告)号：US07456957B2
公开(公告)日：2008-11-25
申请号：US11196043
申请日：2005-08-03
申请人： Matthew J. Everett , Yan Zhou , Jochen M. M. Horn , Keith O'Hara , James P. Foley
发明人： Matthew J. Everett , Yan Zhou , Jochen M. M. Horn , Keith O'Hara , James P. Foley
IPC分类号： G01J3/28
CPC分类号： G01N21/4795 , G01J3/02 , G01J3/0205 , G01J3/0208 , G01J3/0216 , G01J3/0224 , G01J3/0256 , G01J3/0286 , G01J3/18 , G01J3/22 , G02B5/1814 , G02B27/4244
摘要： A compact conical diffraction Littrow spectrometer is disclosed. The distortion of the conically diffracted spectral component beams is compensated and as a result, the diffracted spectral beams can still be focused into a substantially straight line to shine onto a detector array. A spectral domain optical coherence tomography (SD-OCT) system incorporating a Littrow spectrometer or a spectrometer having one or more shared focusing element(s) and an SD-OCT system incorporating a spectrometer that is substantially polarization independent are also disclosed.
摘要翻译：公开了一种紧凑的圆锥衍射Littrow光谱仪。对锥形衍射光谱分量光束的失真进行补偿，结果衍射的光束束仍可被聚焦成基本上直线以照射到检测器阵列上。还公开了包含Littrow光谱仪或具有一个或多个共享聚焦元件的光谱仪的光谱相干光学相干断层扫描（SD-OCT）系统和包含基本上偏振无关的光谱仪的SD-OCT系统。

7. 发明申请

US20070076217A1 Optical coherence tomography for eye-length measurement 有权
标题翻译：光学相干断层扫描用于眼睛测量
公开(公告)号：US20070076217A1
公开(公告)日：2007-04-05
申请号：US11243665
申请日：2005-10-05
申请人： Chris Baker , Matthew Everett , Yan Zhou , Keith O'Hara
发明人： Chris Baker , Matthew Everett , Yan Zhou , Keith O'Hara
IPC分类号： G01B11/02
CPC分类号： A61B3/102 , A61B3/1005 , A61B5/0066
摘要： An accurate measure of eye length can be obtained using concurrent OCT measurements. A position OCT device can be used to continually monitor the position of the front surface of the cornea, while a distance OCT device can determine the apparent distance between the front surface of the cornea and the front surface of the retina. Since the eye is likely to move during the period of time between measurements of the cornea and retina, the monitored position of the cornea can be used to correct the apparent length measurement by the amount of eye movement over that period of time, in order to obtain an accurate measure of eye length. In some embodiments a single OCT device can serve the dual role of monitoring eye position while making eye length measurements
摘要翻译：使用并行OCT测量可以获得眼睛长度的精确测量。位置OCT装置可以用于连续监视角膜前表面的位置，而距离OCT装置可以确定角膜前表面和视网膜的前表面之间的表观距离。由于眼睛可能在角膜和视网膜的测量之间的时间段期间移动，所以可以使用角膜的监视位置来校正视力长度测量量在该时间段内的眼睛移动量，以便获得眼睛长度的准确度量。在一些实施例中，单个OCT设备可以起到监视眼睛位置的双重作用，同时进行眼睛长度测量

8. 发明授权

US07437071B2 Distributive optical switching control system 有权
标题翻译：分布式光交换控制系统
公开(公告)号：US07437071B2
公开(公告)日：2008-10-14
申请号：US10102142
申请日：2002-03-19
申请人： Sudharshan Bhat , Kirk Evans , Raffi Garabedian , Keith O'Hara , Nim Tea
发明人： Sudharshan Bhat , Kirk Evans , Raffi Garabedian , Keith O'Hara , Nim Tea
IPC分类号： H04B10/00
CPC分类号： G02B6/3588 , G02B6/3512 , G02B6/3546
摘要： A localized and distributive optical switching control system is separated into three localized systems: a sensor system, a processor system, and a position driver system. The sensor system detects the light transmission efficiency from the input port to the output port, and sends an error signal to the processor system; the processor system processes the error signal and, based upon predefined compensators and control algorithms, generates a control output signal to rectify the error to the sending and/or receiving position driver(s); the position driver(s) receives the control output signal then repositions the sending and/or receiving mirror(s) to the desired position for optimum signal transmission. The amount of communication data and the amount of routing paths between components are reduced, thus decreasing system reaction time and heat generated, allowing controls to be installed on smaller circuits, such as ASIC, and the arrays to be placed closer together.
摘要翻译：局部和分布式光交换控制系统分为三个本地化系统：传感器系统，处理器系统和位置驱动器系统。传感器系统检测从输入端口到输出端口的光传输效率，并向处理器系统发送错误信号; 处理器系统处理误差信号，并且基于预定义的补偿器和控制算法，产生控制输出信号以将错误校正到发送和/或接收位置驱动器; 位置驱动器接收控制输出信号，然后将发送和/或接收反射镜重新定位到期望的位置，以实现最佳的信号传输。通信数据量和组件之间的路由路径数量减少，从而减少系统反应时间和产生的热量，从而使控制能够安装在较小的电路（如ASIC）上，并将阵列放置在更靠近的位置。

9. 发明申请

US20060164639A1 Cross-dispersed spectrometer in a spectral domain optical coherence tomography system 失效
标题翻译：交叉分散光谱仪在光谱域光学相干断层扫描系统中
公开(公告)号：US20060164639A1
公开(公告)日：2006-07-27
申请号：US11333134
申请日：2006-01-17
申请人： Jochen Horn , Keith O'Hara
发明人： Jochen Horn , Keith O'Hara
IPC分类号： G01J3/28
CPC分类号： G01J3/14 , G01J3/02 , G01J3/0208 , G01J3/0224 , G01J3/0256 , G01J3/18 , G01J3/1809 , G01J3/2803 , G01N21/4795
摘要： A spectral-domain optical coherence tomography system using a cross-dispersed spectrometer is disclosed. The interfered optical signal is dispersed by a grating into several orders of diffraction, and these orders of diffraction are separated by an additional dispersive optical element. The spectral interferogram is recorded by a set of linear detector arrays, or by a two-dimensional detector array.
摘要翻译：公开了使用交叉分散光谱仪的光谱域光学相干断层摄影系统。干涉光信号被光栅分散成几个衍射级，这些衍射级由一个附加的色散光学元件分开。光谱干涉图由一组线性检测器阵列或二维检测器阵列记录。

10. 发明授权

US07480059B2 Optical coherence tomography for eye-length measurement 有权
标题翻译：光学相干断层扫描用于眼睛测量
公开(公告)号：US07480059B2
公开(公告)日：2009-01-20
申请号：US12156797
申请日：2008-06-05
申请人： Yan Zhou , Keith O'Hara
发明人： Yan Zhou , Keith O'Hara
IPC分类号： G01B11/02 , A61B3/14
CPC分类号： A61B3/102 , A61B3/1005 , A61B5/0066
摘要： An accurate measure of eye length can be obtained using concurrent OCT measurements. A position OCT device can be used to continually monitor the position of the front surface of the cornea, while a distance OCT device can determine the apparent distance between the front surface of the cornea and the front surface of the retina. Since the eye is likely to move during the period of time between measurements of the cornea and retina, the monitored position of the cornea can be used to correct the apparent length measurement by the amount of eye movement over that period of time, in order to obtain an accurate measure of eye length. In some embodiments a single OCT device can serve the dual role of monitoring eye position while making eye length measurements
摘要翻译：使用并行OCT测量可以获得眼睛长度的精确测量。位置OCT装置可以用于连续监视角膜前表面的位置，而距离OCT装置可以确定角膜前表面和视网膜的前表面之间的表观距离。由于眼睛可能在角膜和视网膜的测量之间的时间段期间移动，所以可以使用角膜的监视位置来校正视力长度测量量在该时间段内的眼睛移动量，以便获得眼睛长度的准确度量。在一些实施例中，单个OCT设备可以起到监视眼睛位置的双重作用，同时进行眼睛长度测量

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