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1. 发明授权

US08239996B2 Toothbrush comprising inclined and tapered bristles 有权
标题翻译：牙刷包括倾斜和渐缩的刷毛
公开(公告)号：US08239996B2
公开(公告)日：2012-08-14
申请号：US11997951
申请日：2006-08-03
申请人： Christine Garbers , André Brunella , Peter Gross
发明人： Christine Garbers , André Brunella , Peter Gross
IPC分类号： A46B9/04
CPC分类号： A46B9/04 , A46D1/00
摘要： A brush head and a toothbrush having a brush head with inclined and tapered bristles. In one aspect, the toothbrush includes a grip part, a head part, and a bristle area with tufts of bristles that are inserted therein. At least one of said tufts of bristles is inclined. The brush head is characterized in that the bristles in the at least one inclined tufts of bristles is tapered.
摘要翻译：刷头和牙刷具有具有倾斜和渐缩的刷毛的刷头。在一个方面，牙刷包括握持部分，头部部分和具有插入其中的刷毛簇的刷毛区域。所述刷毛簇中的至少一个是倾斜的。刷头的特征在于，至少一个倾斜的刷毛簇中的刷毛是渐缩的。

2. 发明授权

US09409960B2 Bis-met histones 有权
标题翻译：双元组蛋白
公开(公告)号：US09409960B2
公开(公告)日：2016-08-09
申请号：US12594664
申请日：2008-04-07
申请人： Peter Gross , Hans Jornvall , Grazyna Formicka-Zeppezauer , Michael Zeppezauer , Michel Thiry
发明人： Peter Gross , Hans Jornvall , Grazyna Formicka-Zeppezauer , Michael Zeppezauer , Michel Thiry
IPC分类号： C07H21/04 , C07K14/47 , A61K38/00
CPC分类号： C07K14/47 , A61K38/00 , Y02A50/409 , Y10T436/143333
摘要： The present invention provides a nucleic acid molecule which encodes a polypeptide consisting of two methionine residues as the first and second N-terminal amino acid residues linked via a peptide bond to a mature eukaryotic histone. The present invention furthermore relates to a vector containing said nucleic acid molecule, a host transformed with said vector, polypeptides encoded by the nucleic acid molecule and pharmaceutical and diagnostic compositions. The present invention also relates to the use of the nucleic acid molecule, vectors, hosts and the polypeptide of the invention for the preparation of a composition for the treatment of diseases. Furthermore, the present invention relates to a method of testing for the presence of the nucleic acid molecule or the polypeptide in a sample and to a kit.
摘要翻译：本发明提供了一种核酸分子，其编码由两个甲硫氨酸残基组成的多肽，作为通过肽键与成熟真核组蛋白连接的第一和第二N-末端氨基酸残基。本发明还涉及含有所述核酸分子的载体，用所述载体转化的宿主，由核酸分子编码的多肽和药物和诊断组合物。本发明还涉及本发明的核酸分子，载体，宿主和多肽在制备用于治疗疾病的组合物中的用途。此外，本发明涉及测试样品和试剂盒中核酸分子或多肽的存在的方法。

3. 发明授权

US08973202B2 Oral hygiene device, particularly a toothbrush, and method for the production thereof 有权
标题翻译：口腔卫生装置，特别是牙刷，及其制造方法
公开(公告)号：US08973202B2
公开(公告)日：2015-03-10
申请号：US13518953
申请日：2011-02-04
申请人： Franz Fischer , Peter Gross , Beat Huber
发明人： Franz Fischer , Peter Gross , Beat Huber
IPC分类号： A46B5/00 , A46B9/04 , A46B15/00
CPC分类号： A46B15/0002 , A46B5/0062 , A46B5/007 , A46B15/0012 , A46B15/004 , A46B2200/1066
摘要： The oral hygiene device, particularly a toothbrush, has in the neck part, a cavity, which is closed off from the surroundings and in which a snap dome is arranged. This snap dome produces an acoustic warning signal when a limiting bending of the neck part is exceeded as a result of a limiting pressing force with which the head part is pressed, for example, against the teeth and gums is exceeded. On the one hand, this has the effect of protecting the snap dome, usually produced from metal, from corrosion and, on the other hand, the cavity serves as a resonance chamber to amplify the warning signal.
摘要翻译：口腔卫生装置，特别是牙刷，在颈部具有一个空腔，该空腔与周围环境相关，并且其中布置有揿钮。当由于头部被按压的限制压力超过颈部部分的极限弯曲而超过该牙齿和牙龈时，该卡形圆顶产生声音警告信号。一方面，这具有保护通常由金属产生的卡扣圆顶免受腐蚀的影响，另一方面，空腔用作共振室以放大警告信号。

4. 发明授权

US08448284B2 Toothbrush with faceted handle 有权
标题翻译：牙刷与多面手柄
公开(公告)号：US08448284B2
公开(公告)日：2013-05-28
申请号：US12225121
申请日：2007-03-23
申请人： Peter Gross , Martin Zwimpfer
发明人： Peter Gross , Martin Zwimpfer
IPC分类号： A46B5/02 , A46B9/04
CPC分类号： A46B15/0055 , A46B5/02 , A46B5/026 , A46B15/0081 , A46B2200/1066
摘要： The toothbrush according to the invention is equipped with a handle of which the surface is formed, at least in certain sections, in a facet-like manner by way of multiplicity of planar surface-area elements. The surface-area elements are arranged directly adjacent to one another and form a network of element edges. The multiplicity of surface-area elements reproduce, more or less, an essentially rounded handle form, this ensuring comfortable use of the toothbrush in different rotary positions in relation to its longitudinal axis.
摘要翻译：根据本发明的牙刷通过多个平面表面区域元件至少在某些部分中以小平面的方式配备有表面形成的手柄。表面积元件彼此直接相邻布置并形成元件边缘网络。表面积元件的多样性或多或少地复制了基本上圆形的手柄形式，这确保了牙刷在相对于其纵向轴线的不同旋转位置中的舒适使用。

5. 发明授权

US08341792B2 Brush head for a toothbrush and method for producing the brush head 有权
标题翻译：用于牙刷的刷头和用于生产刷头的方法
公开(公告)号：US08341792B2
公开(公告)日：2013-01-01
申请号：US11826442
申请日：2007-07-16
申请人： Franz Fischer , Peter Gross
发明人： Franz Fischer , Peter Gross
IPC分类号： A46B9/04 , A46B13/02
CPC分类号： A61C17/222 , A46B7/06 , A46B9/025 , A46B9/026 , A46B9/028 , A46B9/04 , A46B9/045 , A46B9/06 , A46B13/02 , A46B13/023 , A46B15/0002 , A46B15/0032 , A46B2200/1066 , A46D1/00 , A46D1/0276 , A46D1/0284 , A61C17/22 , A61C17/3418 , A61C17/3481 , Y10S15/05
摘要： The brush head of the toothbrush has filaments that are pointed at one end and led through clearances in the bristle carrier. These filaments have a length of about 10-20 mm. The tips of the pointed filaments produce a height profile other than that of a plane and the ends of the pointed filaments that are remote from the tips are melted.
摘要翻译：牙刷的刷头具有指向一端并穿过刷毛载体中的间隙的细丝。这些长丝具有约10-20mm的长度。尖的长丝的尖端产生与平面不同的高度分布，并且远离尖端的尖的长丝的端部被熔化。

6. 发明授权

US08105516B2 Method and apparatus for producing a coal cake for coking 有权
标题翻译：用于生产焦化煤饼的方法和设备
公开(公告)号：US08105516B2
公开(公告)日：2012-01-31
申请号：US12308822
申请日：2007-06-20
申请人： Norbert Fiedler , Peter Gross , Franz Steiner
发明人： Norbert Fiedler , Peter Gross , Franz Steiner
IPC分类号： B29C43/00
CPC分类号： C10B45/02
摘要： The invention relates to a method and apparatus for producing a coal cake for coking, in which a bed (3) of coal is compacted in a mold (2) by pulses of hammers (19) which act on the bed, and is solidified to form a block. In accordance with the invention the bed (3) is not only worked on in pulses by the hammers (19) but is also subjected to compression.
摘要翻译：本发明涉及一种用于生产用于焦化的煤饼的方法和设备，其中煤的床（3）通过作用在床上的锤（19）的脉冲在模具（2）中压实，并被固化成形成一个块。根据本发明，床（3）不仅通过锤（19）以脉冲进行加工，而且经受压缩。

7. 发明申请

US20110034370A1 BIS-MET HISTONES 有权
公开(公告)号：US20110034370A1
公开(公告)日：2011-02-10
申请号：US12594664
申请日：2008-04-07
申请人： Peter Gross , Hans Jornvall , Grazyna Formicka-Zeppezauer , Michael Zeppezauer , Michel Thiry
发明人： Peter Gross , Hans Jornvall , Grazyna Formicka-Zeppezauer , Michael Zeppezauer , Michel Thiry
IPC分类号： A61K38/16 , C07H21/00 , C12N15/63 , C12N5/10 , C12N1/19 , C12N1/15 , C12N1/21 , C12P21/00 , C07K2/00 , A61K38/02 , A61K31/7088 , C07K16/18 , C12N7/00 , G01N33/53 , C12Q1/68 , A61P31/04 , A61P33/02 , A61P35/00 , A61P43/00
CPC分类号： C07K14/47 , A61K38/00 , Y02A50/409 , Y10T436/143333
摘要： The present invention provides a nucleic acid molecule which encodes a polypeptide consisting of two methionine residues as the first and second N-terminal amino acid residues linked via a peptide bond to a mature eukaryotic histone. The present invention furthermore relates to a vector containing said nucleic acid molecule, a host transformed with said vector, polypeptides encoded by the nucleic acid molecule and pharmaceutical and diagnostic compositions. The present invention also relates to the use of the nucleic acid molecule, vectors, hosts and the polypeptide of the invention for the preparation of a composition for the treatment of diseases. Furthermore, the present invention relates to a method of testing for the presence of the nucleic acid molecule or the polypeptide in a sample and to a kit.
摘要翻译：本发明提供了一种核酸分子，其编码由两个甲硫氨酸残基组成的多肽，作为通过肽键与成熟真核组蛋白连接的第一和第二N-末端氨基酸残基。本发明还涉及含有所述核酸分子的载体，用所述载体转化的宿主，由核酸分子编码的多肽和药物和诊断组合物。本发明还涉及本发明的核酸分子，载体，宿主和多肽在制备用于治疗疾病的组合物中的用途。此外，本发明涉及测试样品和试剂盒中核酸分子或多肽的存在的方法。

8. 发明申请

US20080315668A1 Method and Device for Producing a Toothbrush by the Two-Component or Multi-Component Injection-Molding Process 有权
标题翻译：通过双组分或多组分注射成型工艺生产牙刷的方法和装置
公开(公告)号：US20080315668A1
公开(公告)日：2008-12-25
申请号：US11632042
申请日：2005-07-12
申请人： Beat Huber , Peter Gross
发明人： Beat Huber , Peter Gross
IPC分类号： A46B9/04 , A46D3/04
CPC分类号： B29C45/16 , B29C45/0053 , B29C45/0062 , B29C45/1671 , B29C45/1676 , B29C2045/2683 , B29L2031/425
摘要： The invention relates to a method and a device for producing a toothbrush (50) or part thereof by the two-component or multi-component injection-molding process. To produce in the brush body segments (20) that are isolated from the rest of the brush body, a mold (10) which comprises three hollow regions (12, 14, 16) is used. Two of these hollow regions (12, 14) that are separate from one another serve for producing the segments (12) and the other regions (18) of the toothbrush (50) from a first component (38). A third hollow region (16) serves for distributing material to the segments (20) that are isolated from one another and from the other regions (18), or the corresponding hollow region (14). The material (22) remaining behind there is removed and sent for disposal. In a further step, connecting elements (42) between the segments (20) and/or the other regions (18) are injection-molded from a second component (39).
摘要翻译：本发明涉及通过双组分或多组分注射成型方法生产牙刷（50）或其一部分的方法和装置。为了在与刷体的其余部分分离的刷体段（20）中产生包括三个中空区域（12,14,16）的模具（10）。这些彼此分开的中空区域（12,14）中的两个用于从第一部件（38）制造牙刷（50）的段（12）和其它区域（18）。第三中空区域（16）用于将材料分配到彼此隔离并且与其它区域（18）或相应的中空区域（14）隔离的段（20）。剩下的物料（22）被取出并送出处置。在另一步骤中，段（20）和/或其他区域（18）之间的连接元件（42）由第二部件（39）注模。

9. 发明授权

US06687940B1 Toothbrush 有权
标题翻译：牙刷
公开(公告)号：US06687940B1
公开(公告)日：2004-02-10
申请号：US09807115
申请日：2001-05-21
申请人： Peter Gross , Peter Waldispuhl
发明人： Peter Gross , Peter Waldispuhl
IPC分类号： A46B502
CPC分类号： A46B5/026 , A46B5/02
摘要： The invention comprises a toothbrush having improved manipulative and aesthetic features. The toothbrush includes a joined two-piece construction having a hollow or tubular interior cavity, and wherein the two pieces may be of differing configurations, differing plastic material, differing colors, partially or wholly translucent, and wherein ornamental objects may occupy the cavity when the toothbrush includes transparent portions. The handle also may include soft protuberances to facilitate gripping the toothbrush.
摘要翻译：本发明包括具有改进的操纵和美观特征的牙刷。牙刷包括具有中空或管状内部空腔的连接的两件式结构，并且其中两件可具有不同的构造，不同的塑料材料，不同的颜色，部分或全部是半透明的，并且其中装饰物可以占据空腔牙刷包括透明部分。手柄还可以包括软突起以便于抓住牙刷。

10. 发明授权

US6002020A Process for the catalytic preparation of 3-isochromanones from phthalans 失效
标题翻译：从邻苯二甲酸酯催化制备3-异色满酮的方法
公开(公告)号：US6002020A
公开(公告)日：1999-12-14
申请号：US239001
申请日：1999-01-27
申请人： Holger Geissler , Daniel Decker , Peter Gross
发明人： Holger Geissler , Daniel Decker , Peter Gross
IPC分类号： B01J23/44 , B01J27/13 , C07B61/00 , C07D311/76 , C07D311/10 , C07D311/14 , C07D311/16
CPC分类号： C07D311/76
摘要： Good yields and selectivities are achieved in a process for preparing an isochroman-3-one of the formula (I) ##STR1## by reacting a 1,3-dihydroisobenzofuran of the formula (II) ##STR2## with carbon monoxide at a CO pressure of from 0.1 to 20 MPa in the presence of an ionic halide, a palladium catalyst and a dipolar aprotic solvent.
摘要翻译：通过使式（II）的1,3-二氢异苯并呋喃与一氧化碳在0.1〜20MPa的CO压力下反应，制备式（I）的异苯并二氢吡喃-3-酮的方法得到良好的收率和选择性在离子卤化物，钯催化剂和偶极非质子溶剂的存在下。

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