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1. 发明授权

US09957809B2 Modified interface around a hole 有权
公开(公告)号：US09957809B2
公开(公告)日：2018-05-01
申请号：US14356464
申请日：2012-09-14
申请人： Christian Amann , Thomas Beck , Björn Beckmann , Andreas Böttcher , Winfried Esser , Giuseppe Gaio , Rudolf Küperkoch , Eckart Schumann , Rostislav Teteruk
发明人： Christian Amann , Thomas Beck , Björn Beckmann , Andreas Böttcher , Winfried Esser , Giuseppe Gaio , Rudolf Küperkoch , Eckart Schumann , Rostislav Teteruk
IPC分类号： B32B3/24 , F01D5/18 , F01D5/28
CPC分类号： F01D5/186 , F01D5/18 , F01D5/28 , F01D5/288 , F05D2230/90 , F05D2260/22141 , Y02T50/676 , Y10T428/24273 , Y10T428/24322
摘要： A layer system including a substrate and a layer is provided. The layer system has a hole at least in the layer, and wherein at least one recess is present in a surface of the layer in a vicinity around the hole or directly adjoining a boundary line of the hole.

2. 发明申请

US20140349065A1 MODIFIED INTERFACE AROUND A HOLE 有权
标题翻译：孔改良界面
公开(公告)号：US20140349065A1
公开(公告)日：2014-11-27
申请号：US14356464
申请日：2012-09-14
申请人： Christian Amann , Thomas Beck , Bjorn Beckmann , Andreas Böttcher , Winfried Esser , Giuseppe Gaio , Rudolf Küperkoch , Eckart Schumann , Rostislav Teteruk
发明人： Christian Amann , Thomas Beck , Bjorn Beckmann , Andreas Böttcher , Winfried Esser , Giuseppe Gaio , Rudolf Küperkoch , Eckart Schumann , Rostislav Teteruk
IPC分类号： F01D5/18 , F01D5/28
CPC分类号： F01D5/186 , F01D5/18 , F01D5/28 , F01D5/288 , F05D2230/90 , F05D2260/22141 , Y02T50/676 , Y10T428/24273 , Y10T428/24322
摘要： A layer system including a substrate and a layer is provided. The layer system has a hole at least in the layer, and wherein at least one recess is present in a surface of the layer in a vicinity around the hole or directly adjoining a boundary line of the hole.
摘要翻译：提供了包括衬底和层的层系统。层系统至少在该层中具有孔，并且其中至少一个凹部存在于该孔周围的附近的表面中或者直接邻接该孔的边界线。

3. 发明授权

US10132904B2 Generation of MR images with prospective motion correction and partial-volume-specific weighting of image information 有权
公开(公告)号：US10132904B2
公开(公告)日：2018-11-20
申请号：US15459925
申请日：2017-03-15
申请人： Thomas Beck
发明人： Thomas Beck
IPC分类号： G01V3/00 , G01R33/567 , G01R33/483 , G01R33/565
摘要： A method for creating a magnetic resonance (MR) image with prospective motion correction with a recording of navigation signals and navigator reference signals for the determination of motion information is provided. During the determination of the motion information, the partial volumes of the navigator volume are not all treated equally. Different weightings are used.

4. 发明申请

US20140292333A1 Establishing a Magnetic Resonance System Actuation Sequence 有权
标题翻译：建立磁共振系统动作序列
公开(公告)号：US20140292333A1
公开(公告)日：2014-10-02
申请号：US14231118
申请日：2014-03-31
申请人： Thomas Beck , Rainer Schneider
发明人： Thomas Beck , Rainer Schneider
IPC分类号： G01R33/54
CPC分类号： G01R33/543 , G01R33/243 , G01R33/246 , G01R33/583
摘要： A method for establishing a magnetic resonance system actuation sequence is described. A first number of field distribution maps are acquired for slices of the measurement region, and a radiofrequency pulse train is established on the basis thereof for the magnetic resonance system actuation sequence. This acquisition of the first number of field distribution maps may be brought about on the basis of an acquisition scheme. A reduced number of field distribution representation maps are established on the basis of the acquired field distribution maps, which field distribution representation maps represent the first number of acquired field distribution maps in accordance with a predetermined optimization criterion, and the radiofrequency pulse train is established on the basis of the field distribution representation maps.
摘要翻译：描述了一种用于建立磁共振系统致动顺序的方法。对于测量区域的切片获取第一数量的场分布图，并且基于磁共振系统致动序列建立射频脉冲串。可以在采集方案的基础上获得对第一数量的现场分布图的获取。基于所获取的场分布图建立减少数量的场分布表示图，该场分布表示映射根据预定的优化准则表示所获取的场分布图的第一数量，并且射频脉冲序列建立在现场分布表示图的基础。

5. 发明授权

US08716225B2 Kallikrein inhibitors and anti-thrombolytic agents and uses thereof 有权
标题翻译：激肽释放酶抑制剂和抗溶栓剂及其用途
公开(公告)号：US08716225B2
公开(公告)日：2014-05-06
申请号：US13458086
申请日：2012-04-27
申请人： Henry Blair , Thomas Beck , Robert C. Ladner
发明人： Henry Blair , Thomas Beck , Robert C. Ladner
IPC分类号： A61K38/16 , A61P7/02 , C07K14/00
CPC分类号： A61K38/55 , A61K31/195 , A61K38/57 , A61K45/06 , A61K2300/00
摘要： Methods, kits and compositions are described that include a non-naturally occurring kallikrein inhibitor and an anti-thrombolytic agent, e.g., an anti-fibrinolytic agent, for preventing or reducing blood loss and/or ischemia, e.g., ischemia associated with perioperative blood loss and cerebral ischemia, the onset of systemic inflammatory response, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia or a focal brain ischemia, e.g., in patients subjected to invasive surgical procedures, especially procedures requiring cardiopulmonary bypass.
摘要翻译：描述了包括非天然存在的激肽释放酶抑制剂和抗血栓溶解剂（例如抗纤维蛋白溶解剂）的方法，试剂盒和组合物，用于预防或减少失血和/或缺血，例如与围手术期失血相关的缺血脑缺血，全身炎症反应发作和/或再灌注损伤，例如与脑缺血或局灶性脑缺血相关的再灌注损伤，例如在经历侵入性外科手术的患者中，特别是需要体外循环的手术。

6. 发明申请

US20120145678A1 Method for Producing a Hole 有权
标题翻译：生产孔的方法
公开(公告)号：US20120145678A1
公开(公告)日：2012-06-14
申请号：US13397057
申请日：2012-02-15
申请人： Thomas Beck , Nigel-Philip Cox , Silke Settegast
发明人： Thomas Beck , Nigel-Philip Cox , Silke Settegast
IPC分类号： B23K15/08 , B23K26/38
CPC分类号： B23K15/085 , B23K26/384 , B23K26/389 , B23K2101/001 , F01D5/186 , F05D2230/13 , Y02T50/67 , Y02T50/676 , Y10T29/49341
摘要： There are a multiplicity of methods of making through-holes. In particular in the production of a multiplicity of film-cooling holes, as in gas turbine blades or combustion chamber elements, small time advantages are also important when making a hole. The method according to the invention, to make the hole close to the final contour in each case in sections in a top and a bottom region in order to then produce the final contour with other laser parameters, achieves time advantages.
摘要翻译：有多种形成通孔的方法。特别是在制造多个薄膜冷却孔时，如在燃气轮机叶片或燃烧室元件中，小的时间优点在制造孔时也是重要的。根据本发明的方法，为了使其在顶部和底部区域中的每一种情况下，使得孔接近于最终轮廓，以便随后用其他激光参数产生最终轮廓，这实现了时间优点。

7. 发明授权

US08153923B2 Method for producing a hole 有权
标题翻译：孔的制造方法
公开(公告)号：US08153923B2
公开(公告)日：2012-04-10
申请号：US12087720
申请日：2006-12-29
申请人： Thomas Beck , Nigel-Philip Cox , Silke Settegast
发明人： Thomas Beck , Nigel-Philip Cox , Silke Settegast
IPC分类号： F01D5/18 , B23K15/08 , B23K26/36
CPC分类号： B23K15/085 , B23K26/384 , B23K26/389 , B23K2101/001 , F01D5/186 , F05D2230/13 , Y02T50/67 , Y02T50/676 , Y10T29/49341
摘要： There are a multiplicity of methods of making through-holes. In particular in the production of a multiplicity of film-cooling holes, as in gas turbine blades or combustion chamber elements, small time advantages are also important when making a hole. The method according to the invention, to make the hole close to the final contour in each case in sections in a top and a bottom region in order to then produce the final contour with other laser parameters, achieves time advantages.
摘要翻译：有多种形成通孔的方法。特别是在制造多个薄膜冷却孔时，如在燃气轮机叶片或燃烧室元件中，小的时间优点在制造孔时也是重要的。根据本发明的方法，为了使其在顶部和底部区域中的每一种情况下，使得孔接近于最终轮廓，以便随后用其他激光参数产生最终轮廓，这实现了时间优点。

8. 发明授权

US07717058B2 Method of preparing turbine blades for spray coating and mounting for fixing such a turbine blade 有权
标题翻译：制备用于喷涂和安装涡轮叶片的涡轮叶片的方法
公开(公告)号：US07717058B2
公开(公告)日：2010-05-18
申请号：US11518554
申请日：2006-09-08
申请人： Thomas Beck , Francis-Jurjen Ladru , Benjamin Lippke , Marcus Mensing
发明人： Thomas Beck , Francis-Jurjen Ladru , Benjamin Lippke , Marcus Mensing
IPC分类号： B05C21/00
CPC分类号： C23C4/01 , B05B12/20
摘要： The invention relates to a method of preparing turbine blades for spray coating their blade region that is subjected to the medium flowing through during operation in a spray coating apparatus, in which the turbine blade is inserted with its blade root into a cavity of a mounting in such a way that it protrudes with the blade region that adjoins the blade root from an opening of the cavity to form a gap between the rim of the opening and the turbine blade, and in which the gap is bridged by a shielding fixed on the mounting, which is characterized in that a shielding layer of a plastic which is resistant during the spray coating is used for the shielding, the shielding layer being arranged in such a way that it reaches up to the boundary between the blade root and the blade region.
摘要翻译：本发明涉及一种制备涡轮机叶片的方法，用于在喷涂装置中在其操作期间经受介质流动的叶片区域喷涂其中，其中涡轮机叶片以其叶片根部插入安装的空腔中这样一种方式使得其与从腔的开口邻接叶片根部的叶片区域突出，以在开口的边缘和涡轮叶片之间形成间隙，并且其中间隙由固定在安装件上的屏蔽物桥接其特征在于，在喷涂期间耐用的塑料的屏蔽层用于屏蔽，屏蔽层以使其到达叶片根部和叶片区域之间的边界的方式布置。

9. 发明申请

US20090227494A1 Kallikrein Inhibitors and Anti-Thrombolytic Agents and Uses Thereof 审中-公开
公开(公告)号：US20090227494A1
公开(公告)日：2009-09-10
申请号：US11931361
申请日：2007-10-31
申请人： Henry Blair , Thomas Beck , Robert C. Ladner
发明人： Henry Blair , Thomas Beck , Robert C. Ladner
IPC分类号： A61K38/16
CPC分类号： A61K38/55 , A61K31/195 , A61K38/57 , A61K45/06 , A61K2300/00
摘要： Methods, kits and compositions are described that include a non-naturally occurring kallikrein inhibitor and an anti-thrombolytic agent, e.g., an anti-fibrinolytic agent, for preventing or reducing blood loss and/or ischemia, e.g., ischemia associated with perioperative blood loss and cerebral ischemia, the onset of systemic inflammatory response, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia or a focal brain ischemia, e.g., in patients subjected to invasive surgical procedures, especially procedures requiring cardiopulmonary bypass.

10. 发明申请

US20080197120A1 Method For Producing a Hole and Associated Device 审中-公开
标题翻译：生产孔和相关设备的方法
公开(公告)号：US20080197120A1
公开(公告)日：2008-08-21
申请号：US11795284
申请日：2005-12-21
申请人： Thomas Beck , Silke Settegast , Lutz Wolkers
发明人： Thomas Beck , Silke Settegast , Lutz Wolkers
IPC分类号： B23K26/38
CPC分类号： B23K26/0604 , B23K26/384 , B23K26/389 , B23K2101/001
摘要： Conventional methods for producing a hole in a component make use of special lasers with short laser pulse lengths. The aim of the invention is to reduce the time and money required for producing a hole. According to the inventive method, the laser pulse lengths are varied, short laser pulse lengths only being used in the area to be removed in which an influence on the throughflow or exhaust behavior is noticeable. This is, e.g., the inner surface of a diffuser of a hole that can be produced in a very precise manner using short laser pulse lengths.
摘要翻译：用于在部件中产生孔的常规方法使用具有短激光脉冲长度的特殊激光器。本发明的目的是减少生产孔所需的时间和金钱。根据本发明的方法，激光脉冲长度是变化的，仅在要去除的区域中使用短的激光脉冲长度，其中对通流或排气行为的影响是显着的。这是例如可以使用短激光脉冲长度以非常精确的方式制造的孔的扩散器的内表面。

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