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    • 5. 发明授权
    • Optical transceiver with polarity inversion
    • 带极性反转的光收发器
    • US08556523B2
    • 2013-10-15
    • US12984502
    • 2011-01-04
    • Thomas Beck MasonWei-Chiao Fang
    • Thomas Beck MasonWei-Chiao Fang
    • G02B6/36
    • H04B10/40
    • An optical transceiver that includes a modification that prevents interoperability with standard transceivers, while enabling them to work in the same slots and equipment as standard transceivers, provided that they are interoperating with a similarly modified transceiver on the other end of the optical link. Ideally, the polarity of the data in both the transmit and receive direction is inverted resulting in valid data for a link when a pair of modified modules are used and invalid data when a modified module is used with a standard fiber optic transceiver. The function is otherwise transparent to the host equipment.
    • 一种光收发器,其包括防止与标准收发器的互操作性的修改,同时使得它们能够在与标准收发器相同的插槽和设备中工作,只要它们与光链路的另一端上的类似修改的收发器互操作即可。 理想情况下,当使用一对修改的模块时,发送和接收方向上的数据的极性被反转,当修改的模块与标准光纤收发器一起使用时,链路的有效数据被反转,并且无效数据。 该功能对主机设备来说是透明的。
    • 8. 发明申请
    • Molecularly Imprinted Polymers for Use as Imaging and Therapeutics Agents
    • 分子印迹聚合物用作成像和治疗剂
    • US20120093720A1
    • 2012-04-19
    • US13274093
    • 2011-10-14
    • Robert JonesThomas Beck
    • Robert JonesThomas Beck
    • A61K49/00A61K51/06C08G65/34
    • A61K49/0002A61K51/06A61K51/1244C08G65/329C08L71/02C08L2203/02
    • The invention described herein provides biocompatible molecularly imprinted polymers (MIPs) that are non-toxic, water soluble, small molecular weight, and degradable in a living body. The MIPs are capable of binding to all or a portion of a specific target macromolecule associated with a disease located within the living body and they are derivatized for stealth for in vivo applications to avoid the reticuloendothelial system. The MIPs of the invention are functionalized to an amine or carboxyl group and are derivatized with an imaging and/or therapeutic agent for taking images of the disease and/or for providing therapy. The macromolecule can be selected from a group consisting of proteins, glycoproteins, lipoproteins, peptidoglycans, peptides, polypeptides, polynucleotides, and polysaccharides. The invention described herein also provides methods and kits wherein MIPs of the invention can be employed as targeted imaging and therapeutic agents.
    • 本文描述的本发明提供了生物相容性分子印迹聚合物(MIP),其在生物体中是无毒的,水溶性的,小分子量的和可降解的。 MIP能够结合与位于生物体内的疾病相关的特定目标大分子的全部或一部分,并且它们被衍生化用于隐形以用于体内应用以避免网状内皮系统。 本发明的MIP被官能化为胺或羧基,并且用成像和/或治疗剂衍生以获取疾病图像和/或用于提供治疗。 大分子可以选自蛋白质,糖蛋白,脂蛋白,肽聚糖,肽,多肽,多核苷酸和多糖。 本文所述的发明还提供了本发明的MIP可用作靶向成像和治疗剂的方法和试剂盒。