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1. 发明申请

US20100041848A1 AMPHIPHILIC POLYMER AND METHOD FOR PREPARING THE SAME 审中-公开
标题翻译：聚合聚合物及其制备方法
公开(公告)号：US20100041848A1
公开(公告)日：2010-02-18
申请号：US12352274
申请日：2009-01-12
申请人： Chia-Chang Liu , Ken-Yuan Chang , Fa-Chen Chi
发明人： Chia-Chang Liu , Ken-Yuan Chang , Fa-Chen Chi
IPC分类号： C08F251/00
CPC分类号： C08G63/08 , C07H15/02 , C08G63/912 , C08G2261/126
摘要： An amphiphilic polymer having the following formula (I): wherein Z is a hydroxyl-substituted aliphatic group having formula (Z1) or (Z2): wherein R11 and R21 are independently hydrogen, hydroxyl, hydroxymethyl, methyl, or a C1-C20 alkyl group, and R12, R13, R14, R22, R23, and R24 are independently hydrogen, hydroxyl, or a sugar moiety;X is a C1-C6 divalent aliphatic group; andY is a biodegradable group having the following formula (II): wherein R′ is a hydrocarbyl group or a polyester block having the following formula (II-A), wherein, in each occurrence, R is hydrogen or a C1-C18 alkyl group, m is an integer ranging from 0 to 5, and n is an integer ranging from 10 to 300.
摘要翻译：具有下式（I）的两亲性聚合物：其中Z是具有式（Z1）或（Z2）的羟基取代的脂族基团：其中R11和R21独立地是氢，羟基，羟甲基，甲基或C1-C20烷基基团，R 12，R 13，R 14，R 22，R 23和R 24独立地为氢，羟基或糖部分; X是C1-C6二价脂族基团; Y为具有下式（II）的生物降解基团：其中R'为烃基或具有下式（II-A）的聚酯嵌段，其中R为氢或C 1 -C 18烷基组，m为0〜5的整数，n为10〜300的整数。

2. 发明授权

US08778325B2 Water-soluble and biodegradable antimicrobial agent 失效
标题翻译：水溶性和生物降解抗菌剂
公开(公告)号：US08778325B2
公开(公告)日：2014-07-15
申请号：US13098788
申请日：2011-05-02
申请人： Chun-Yi Li , Ken-Yuan Chang , Chia-Chang Liu , Ying-Nan Tsai
发明人： Chun-Yi Li , Ken-Yuan Chang , Chia-Chang Liu , Ying-Nan Tsai
IPC分类号： A61K31/74 , A61K47/48 , A01N37/46 , C08G69/10
CPC分类号： C08G69/10 , A01N37/46 , A01N59/00 , A01N2300/00
摘要： A water-soluble and biodegradable antimicrobial agent is provided, comprising a polymer composed of a segment A and a segment B, in which, the segment A has the following formula I: the segment B has the following formula II: wherein the segment A and the segment B in the polymer have a molar ratio of 1:0.007-1.2, and n is 0 or 1, m is an integer of 0-2, m+n≠0, X is H, Na, K, NH4, ½Ca, or ½Mg, and Y is Cl, Br, or I.
摘要翻译：提供了一种水溶性和可生物降解的抗微生物剂，其包含由段A和段B组成的聚合物，其中段A具有下式I：段B具有下式II：其中段A和聚合物中的链段B的摩尔比为1:0.007-1.2，n为0或1，m为0-2的整数，m + n≠0，X为H，Na，K，NH 4，½Ca ，或½Mg，Y是Cl，Br或I.

3. 发明申请

US20120083439A1 Method of Preparing Water-Soluble and Biodegradable Antimicrobial Agent 失效
标题翻译：制备水溶性和生物降解性抗微生物剂的方法
公开(公告)号：US20120083439A1
公开(公告)日：2012-04-05
申请号：US13098814
申请日：2011-05-02
申请人： Chun-Yi Li , Ken-Yuan Chang , Chia-Chang Liu , Ying-Nan Tsai
发明人： Chun-Yi Li , Ken-Yuan Chang , Chia-Chang Liu , Ying-Nan Tsai
IPC分类号： A01N37/36 , A01P1/00
CPC分类号： A01N37/46 , A01N59/00 , A01N2300/00
摘要： A method of preparing a water-soluble and biodegradable antimicrobial agent is provided. The method includes treating a polypeptide compound with sodium hypochlorite for at least 1 min, such that the polypeptide compound has at least one N-halamine group and has good antimicrobial effect. By using the method of the present invention, a chemical synthesis process is not required and an organic solvent is not required either, and thus, an antimicrobial agent having high water solubility, biodegradability, non-toxicity, good sterilization effect, and regeneration can be prepared with reduced harms to the environment.
摘要翻译：提供了制备水溶性和可生物降解的抗微生物剂的方法。该方法包括用次氯酸钠处理多肽化合物至少1分钟，使得多肽化合物具有至少一个N-卤代胺基团并且具有良好的抗微生物作用。通过使用本发明的方法，不需要化学合成方法，也不需要有机溶剂，因此具有高水溶性，生物降解性，无毒性，良好灭菌效果和再生的抗微生物剂可以是准备减少对环境的危害。

4. 发明授权

US08530405B2 Method of preparing water-soluble and biodegradable antimicrobial agent 失效
标题翻译：制备水溶性和生物可降解抗微生物剂的方法
公开(公告)号：US08530405B2
公开(公告)日：2013-09-10
申请号：US13098814
申请日：2011-05-02
申请人： Chun-Yi Li , Ken-Yuan Chang , Chia-Chang Liu , Ying-Nan Tsai
发明人： Chun-Yi Li , Ken-Yuan Chang , Chia-Chang Liu , Ying-Nan Tsai
IPC分类号： A01N37/18 , A61K38/00 , A61P31/00
CPC分类号： A01N37/46 , A01N59/00 , A01N2300/00
摘要： A method of preparing a water-soluble and biodegradable antimicrobial agent is provided. The method includes treating a polypeptide compound with sodium hypochlorite for at least 1 min, such that the polypeptide compound has at least one N-halamine group and has good antimicrobial effect. By using the method of the present invention, a chemical synthesis process is not required and an organic solvent is not required either, and thus, an antimicrobial agent having high water solubility, biodegradability, non-toxicity, good sterilization effect, and regeneration can be prepared with reduced harms to the environment.
摘要翻译：提供了制备水溶性和可生物降解的抗微生物剂的方法。该方法包括用次氯酸钠处理多肽化合物至少1分钟，使得多肽化合物具有至少一个N-卤代胺基团并且具有良好的抗微生物作用。通过使用本发明的方法，不需要化学合成方法，也不需要有机溶剂，因此具有高水溶性，生物降解性，无毒性，良好灭菌效果和再生的抗菌剂可以是准备减少对环境的危害。

5. 发明申请

US20120082638A1 Water-Soluble and Biodegradable Antimicrobial Agent 失效
标题翻译：水溶性和可生物降解的抗微生物剂
公开(公告)号：US20120082638A1
公开(公告)日：2012-04-05
申请号：US13098788
申请日：2011-05-02
申请人： Chun-Yi Li , Ken-Yuan Chang , Chia-Chang Liu , Ying-Nan Tsai
发明人： Chun-Yi Li , Ken-Yuan Chang , Chia-Chang Liu , Ying-Nan Tsai
IPC分类号： A01N37/44 , A01P1/00 , C08G69/10
CPC分类号： C08G69/10 , A01N37/46 , A01N59/00 , A01N2300/00
摘要： A water-soluble and biodegradable antimicrobial agent is provided, comprising a polymer composed of a segment A and a segment B, in which, the segment A has the following formula I: the segment B has the following formula II: wherein the segment A and the segment B in the polymer have a molar ratio of 1:0.007-1.2, and n is 0 or 1, m is an integer of 0-2, m+n≠0, X is H, Na, K, NH4, ½Ca, or ½Mg, and Y is Cl, Br, or I.
摘要翻译：提供了一种水溶性和可生物降解的抗微生物剂，其包含由段A和段B组成的聚合物，其中段A具有下式I：段B具有下式II：其中段A和聚合物中的链段B的摩尔比为1:0.007-1.2，n为0或1，m为0-2的整数，m + n≠0，X为H，Na，K，NH 4，½Ca ，或½Mg，Y是Cl，Br或I.

6. 发明申请

US20080302244A1 Carbon dioxide absorption device 失效
标题翻译：二氧化碳吸收装置
公开(公告)号：US20080302244A1
公开(公告)日：2008-12-11
申请号：US12078357
申请日：2008-03-31
申请人： Chia-Chang Liu
发明人： Chia-Chang Liu
IPC分类号： B01D53/02
CPC分类号： B01D53/62 , B01D2251/102 , B01D2251/104 , B01D2257/504 , B01D2259/818 , Y02A50/2342 , Y02C10/04
摘要： Carbon dioxide contained within exhaust gas is combined with bivalent metal ions such as calcium ions or the like in concentrated salt water to form precipitated calcium carbonate and then can be expelled out. Such an environmental friendly design is realized by a bottle upside down device with a bottle neck exit on a bottom, a piston inside the device can be elevated to a top portion to produce a near vacuum air pressure inside the device. All the brine, exhaust gas, and oxygen, ozone draw together into the device can be accelerated to form, at least, precipitated calcium carbonate to reduce carbon dioxide contained within the exhaust gas. Chemical reaction accelerated by a high voltage discharger below the piston, by flashing a portion of water to atomize the brine. Or a heater can heat up the near vacuum device to accelerate chemical reaction.
摘要翻译：废气中含有的二氧化碳与浓盐水中的二价金属离子如钙离子等结合形成沉淀碳酸钙，然后被排出。这种环境友好的设计是通过瓶子倒置装置实现的，瓶子在底部具有瓶颈出口，装置内部的活塞可以升高到顶部，以在装置内部产生接近的真空气压。可以将所有的盐水，废气和氧气，一起吸入装置中的臭氧加速，至少形成沉淀碳酸钙以减少废气中所含的二氧化碳。化学反应由活塞下方的高压放电器加速，通过闪烁一部分水来雾化盐水。或者加热器可以加热近真空装置以加速化学反应。

7. 外观设计

USD624049S1 Motion detector for gaming controller 有权
标题翻译：游戏控制器运动检测器
公开(公告)号：USD624049S1
公开(公告)日：2010-09-21
申请号：US29274973
申请日：2007-06-14
申请人： Chia-Chang Liu
设计人： Chia-Chang Liu

8. 发明授权

US08771571B2 Method for preparing high water-absorption and anti-bacterial gamma polyglutamic acid fibers 有权
标题翻译：制备高吸水和抗菌γ聚谷氨酸纤维的方法
公开(公告)号：US08771571B2
公开(公告)日：2014-07-08
申请号：US13051236
申请日：2011-03-18
申请人： Jo-Wei Huang , Chia-Chang Liu , Ying-Nan Tsai
发明人： Jo-Wei Huang , Chia-Chang Liu , Ying-Nan Tsai
IPC分类号： D01D1/02 , D04H13/00 , C08G69/08 , C08G69/10
CPC分类号： C08G69/08 , C08G69/10 , D01F1/10 , D01F6/68 , D04H1/30 , D04H1/4266 , D04H13/00 , D06M11/07 , D06M11/11 , D06M11/70 , D06M16/00 , Y10T428/2913 , Y10T442/2525 , Y10T442/696
摘要： A method for preparing a polyglutamic acid (γ-PGA) fiber having antibacterial and water absorption properties is provided. The method includes providing a γ-PGA fiber and immersing it in a sodium hypochlorite solution. A relation exists between an immersing time T of the γ-PGA fiber and a concentration X of the sodium hypochlorite solution as shown in the formula below: 10.2≦(T−64.55X2+50X)≦15.2, wherein X is 0.006-0.4 wt %.
摘要翻译：提供了具有抗菌吸水性的聚谷氨酸（γ-PGA）纤维的制造方法。该方法包括提供γ-PGA纤维并将其浸入次氯酸钠溶液中。如下式所示，γ-PGA纤维的浸渍时间T和次氯酸钠溶液的浓度X之间存在关系：10.2＆nlE;（T-64.55X2 + 50X）＆lt; 15;其中X为0.006- 0.4重量％。

9. 发明申请

US20120253449A1 Stent 审中-公开
标题翻译：支架
公开(公告)号：US20120253449A1
公开(公告)日：2012-10-04
申请号：US13337688
申请日：2011-12-27
申请人： Fuh-Yu Chang , Chia-Chang Liu , Min-Hua Chen , Po-Chin Liang , Yu-Ting Chang , Kai-Wen Huang , Yi-Chao Hsu , Hsiao-Chin Cheng , Yu-Ting Fang , Mei-Shey Lin
发明人： Fuh-Yu Chang , Chia-Chang Liu , Min-Hua Chen , Po-Chin Liang , Yu-Ting Chang , Kai-Wen Huang , Yi-Chao Hsu , Hsiao-Chin Cheng , Yu-Ting Fang , Mei-Shey Lin
IPC分类号： A61F2/82
CPC分类号： A61F2/82 , A61F2250/0067 , A61N5/062
摘要： The present invention discloses a stent for supporting a sidewall of a lumen which contains a first fluid. The stent comprises a stent body, a film and a photosensitizing layer. The stent body is disposed inside the lumen. The film is adapted to be penetrated by a light and covers the stent body. The photosensitizing layer is disposed on an outer surface of the film for receiving the light to generate a first object, and the film separates the photosensitizing layer and the first fluid. The film and the photosensitizing layer of the present invention can greatly reduce the needed dosage of the photosensitizer while maintaining the effective concentration of the photosensitizer around tumor cells.
摘要翻译：本发明公开了一种用于支撑包含第一流体的内腔侧壁的支架。支架包括支架体，膜和光敏层。支架主体设置在内腔的内部。该膜适于被光穿透并覆盖支架体。光敏层设置在用于接收光的膜的外表面上以产生第一物体，并且膜分离光敏层和第一流体。本发明的膜和光敏层可以大大减少光敏剂所需的剂量，同时保持光敏剂在肿瘤细胞周围的有效浓度。

10. 发明申请

US20120083179A1 Method for Preparing High Water-Absorption and Anti-Bacterial Fibers 有权
标题翻译：高吸水和抗细菌纤维的制备方法
公开(公告)号：US20120083179A1
公开(公告)日：2012-04-05
申请号：US13051236
申请日：2011-03-18
申请人： Jo-Wei Huang , Chia-Chang Liu , Ying-Nan Tsai
发明人： Jo-Wei Huang , Chia-Chang Liu , Ying-Nan Tsai
IPC分类号： D04H13/00 , B29B9/06 , C08G61/12
CPC分类号： C08G69/08 , C08G69/10 , D01F1/10 , D01F6/68 , D04H1/30 , D04H1/4266 , D04H13/00 , D06M11/07 , D06M11/11 , D06M11/70 , D06M16/00 , Y10T428/2913 , Y10T442/2525 , Y10T442/696
摘要： A method for preparing a polyglutamic acid (γ-PGA) fiber having antibacterial and water absorption properties is provided. The method includes providing a γ-PGA fiber and immersing it in a sodium hypochlorite solution. A relation exists between an immersing time T of the γ-PGA fiber and a concentration X of the sodium hypochlorite solution as shown in the formula below: 10.2≦(T−64.55X2+50X)≦15.2, wherein X is 0.006-0.4 wt %.
摘要翻译：提供了具有抗菌吸水性的聚谷氨酸（γ-PGA）纤维的制备方法。该方法包括提供γ-PGA纤维并将其浸入次氯酸钠溶液中。如下式所示，γ-PGA纤维的浸渍时间T和次氯酸钠溶液的浓度X之间存在关系：10.2＆nlE;（T-64.55X2 + 50X）＆lt; 15;其中X为0.006- 0.4重量％。

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