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1. 发明申请

US20100048680A1 Alpha-1-Antitrypsin Variants and Uses Thereof 审中-公开
标题翻译： α-1-抗胰蛋白酶变体及其用途
公开(公告)号：US20100048680A1
公开(公告)日：2010-02-25
申请号：US12522958
申请日：2008-01-11
申请人： Chen Liu , Hui-Jia Dong
发明人： Chen Liu , Hui-Jia Dong
IPC分类号： A61K31/7088 , C12N5/071 , C12Q1/68 , G01N33/53 , A61P1/16 , A61P37/06
CPC分类号： C07K14/8125 , A61K38/00
摘要： The subject invention is directed to novel polynucleotides and polypeptides comprising SEQ ID NOs: 1 and 2. Also provided arc fragments these polypeptides. The polynucleotides and polypeptides disclosed herein have been isolated from the liver cells (hepatocytes) of end stage liver failure patients and appear to be associated with a poor prognosis for these patients as relates to liver function. The subject application provides therapeutic methods and reagents for treating livers in which the polynucleotide and polypeptide of SEQ ID NO: 1 and 2 are identified as well as diagnostic methods and reagents for identifying individuals at risk of liver failure. Finally, the subject invention also provides a system of the classification, revision or reordering of a classification system of liver transplant patients.
摘要翻译：本发明涉及包含SEQ ID NO：1和2的新型多核苷酸和多肽。还提供了这些多肽的电弧片段。本文公开的多核苷酸和多肽已经从终末期肝衰竭患者的肝细胞（肝细胞）中分离出来，并且与肝功能相关似乎与这些患者的预后差相关。本申请提供了用于治疗其中鉴定了SEQ ID NO：1和2的多核苷酸和多肽的肝脏的治疗方法和试剂以及用于鉴定患有肝衰竭风险的个体的诊断方法和试剂。最后，本发明还提供了肝移植患者分类系统的分类，修订或重新排序的系统。

2. 发明公开

US20240193271A1 ANOMALY DETECTION FRAMEWORK TARGETING RANSOMWARE USING LOW-LEVEL HARDWARE INFORMATION 审中-公开
公开(公告)号：US20240193271A1
公开(公告)日：2024-06-13
申请号：US18538875
申请日：2023-12-13
申请人： Chen Liu , Chutitep Woralert
发明人： Chen Liu , Chutitep Woralert
IPC分类号： G06F21/56
CPC分类号： G06F21/56 , G06F2221/034
摘要： A semi-supervised machine learning system and method to detect ransomware using low-level hardware information. Employing semi-supervised learning method on performance counter data for anomaly prediction, the system can detect ransomware in real-time with its online detection process.

3. 发明授权

US09546526B2 Torque wrench apparatus and method for making and breaking joints 有权
标题翻译：扭力扳手装置及接头断裂方法
公开(公告)号：US09546526B2
公开(公告)日：2017-01-17
申请号：US14840919
申请日：2015-08-31
申请人： Xuejun Li , Chen Liu , Jie Cui
发明人： Xuejun Li , Chen Liu , Jie Cui
IPC分类号： E21B19/16
CPC分类号： E21B19/163
摘要： A torque wrench apparatus comprises a top wrench, a bottom wrench, and a middle wrench. The top and bottom wrenches are configured such that either one of them rotates a first joint in a first direction, and the middle wrench is configured to rotate a second joint in a second direction opposite the first direction; or the top and bottom wrenches are configured such that either one of them immobilizes a first joint, and the middle wrench is configured to rotate a second joint in a first direction; or the middle wrench is configured to immobilize a first joint, and the top and bottom wrenches are configured such that either one of them rotates a second joint in a second direction opposite the first direction. A method for making and breaking joints with the apparatus is also introduced.
摘要翻译：扭矩扳手装置包括顶扳手，底扳手和中间扳手。顶部和底部扳手构造成使得它们中的任一个在第一方向上旋转第一接头，并且中间扳手构造成沿与第一方向相反的第二方向旋转第二接头; 或者顶部和底部扳手构造成使得它们中的任一个固定第一接头，并且中间扳手构造成沿第一方向旋转第二接头; 或所述中间扳手被构造成固定第一接头，并且所述顶部和底部扳手构造成使得它们中的任一个在与第一方向相反的第二方向上旋转第二接头。还介绍了一种用于制造和断开该装置的接头的方法。

4. 发明授权

US09142215B2 Power-efficient voice activation 有权
标题翻译：高效率的语音激活
公开(公告)号：US09142215B2
公开(公告)日：2015-09-22
申请号：US13524584
申请日：2012-06-15
申请人： Stephan Rosner , Chen Liu , Jens Olson
发明人： Stephan Rosner , Chen Liu , Jens Olson
IPC分类号： G10L15/26 , G10L15/22 , G10L25/78
CPC分类号： G10L15/22 , G10L15/08 , G10L15/222 , G10L15/265 , G10L25/78 , G10L2015/088 , H04R29/004
摘要： A voice activation system is provided. The voice activation system includes a first stage configured to output a first activation signal if at least one energy characteristic of a received audio signal satisfies at least one threshold and a second stage configured to transition from a first state to a second state in response to the first activation signal and, when in the second state, to output a second activation signal if at least a portion of a profile of the audio signal substantially matches at least one predetermined profile.
摘要翻译：提供语音激活系统。语音激活系统包括第一级，其被配置为如果所接收的音频信号的至少一个能量特性满足至少一个阈值则输出第一激活信号，并且第二级被配置为响应于所述第一状态从第一状态转变到第二状态并且当处于第二状态时，如果音频信号的轮廓的至少一部分基本上匹配至少一个预定轮廓，则输出第二激活信号。

5. 发明申请

US20130034532A1 NANOZYMES, METHODS OF MAKING NANOZYMES, AND METHODS OF USING NANOZYMES 审中-公开
标题翻译：纳米颗粒，制备纳米颗粒的方法和使用纳米颗粒的方法
公开(公告)号：US20130034532A1
公开(公告)日：2013-02-07
申请号：US13641590
申请日：2011-04-19
申请人： Yunwei Charles Cao , Chen Liu , Hongyan Liu , Zhongliang Wang , Soon Hye Yang
发明人： Yunwei Charles Cao , Chen Liu , Hongyan Liu , Zhongliang Wang , Soon Hye Yang
IPC分类号： C12N9/96 , A61K38/43 , B82Y5/00
CPC分类号： B82Y5/00 , A61K38/00 , A61K47/549 , A61K47/6923 , A61K47/6929 , C12N9/96
摘要： Embodiments of the present disclosure provides for nanozymes, methods of making nanozymes, methods of using nanozymes, and the like.
摘要翻译：本公开的实施方案提供了纳米酶，制备纳米酶的方法，使用纳米酶的方法等。

6. 发明申请

US20100076018A1 Compounds and Methods for Treatment of Alpha-1 Antitrypsin Deficiency 失效
标题翻译：用于治疗α-1抗胰蛋白酶缺乏症的化合物和方法
公开(公告)号：US20100076018A1
公开(公告)日：2010-03-25
申请号：US12500540
申请日：2009-07-09
申请人： Chen Liu , David A. Ostrov
发明人： Chen Liu , David A. Ostrov
IPC分类号： A61K31/47 , C12N5/02 , A61K31/01 , A61K31/415 , A61K31/357 , A61K31/336 , A61K31/22 , A61K31/38 , A61K31/045 , G06F19/00
CPC分类号： A61K31/4741
摘要： The invention features compositions and methods that are useful for treating or preventing AAT deficiency and associated conditions. In addition, the invention provides methods for identifying compounds useful for treatment of AAT deficiency and associated conditions.
摘要翻译：本发明的特征在于可用于治疗或预防AAT缺陷和相关病症的组合物和方法。此外，本发明提供了鉴定可用于治疗AAT缺乏症和相关病症的化合物的方法。

7. 发明申请

US20070171026A1 Method and device for controlling switch between appliances 有权
标题翻译：用于控制电器之间切换的方法和装置
公开(公告)号：US20070171026A1
公开(公告)日：2007-07-26
申请号：US11638029
申请日：2006-12-13
申请人： Chen Liu
发明人： Chen Liu
IPC分类号： G05B23/02
CPC分类号： H04N5/4403 , G08C23/04 , G08C2201/92 , H04L12/2814 , H04L12/282 , H04N21/42225 , H04N21/43615
摘要： This invention provides a method and a device for controlling switch between appliances. The method includes: setting a group of control signals according to operations to be performed by appliances involved in a switch between a current appliance and a target appliance; and controlling the appliances involved in the switch between the current appliance and the target appliance to perform operations corresponding to the group of control signals, when the switch is triggered. The method simplifies the operation of switch between appliances in a multi-appliance environment and enables one appliance switching key to control multiple appliances.
摘要翻译：本发明提供一种用于控制电器之间的开关的方法和装置。该方法包括：根据由当前设备和目标设备之间的交换机中涉及的设备执行的操作来设置一组控制信号; 并且当触发开关时，控制与当前设备和目标设备之间的切换中涉及的设备，以执行与该组控制信号相对应的操作。该方法简化了多设备环境中设备之间切换的操作，并使一个设备切换密钥能够控制多个设备。

8. 发明申请

US20070060937A1 Safety needle holder 审中-公开
标题翻译：安全针架
公开(公告)号：US20070060937A1
公开(公告)日：2007-03-15
申请号：US11213758
申请日：2005-08-30
申请人： Chen Liu
发明人： Chen Liu
IPC分类号： A61B17/34
CPC分类号： A61M37/0076
摘要： A safety needle holder for eye or body tattooing purpose that provides reliable operation of the needle, prevents the needle from falling out of its place, and avoids backflow of colorant is comprised of an upper holder containing a transmission shaft, a lower holder containing a needle, and a central holder connecting both of the upper and the lower holders; two flat sections being each made at where approaching both ends of the needle; two resilient members being each inserted to where above and beneath both flat sections; a sleeve being inserted to the lower end of the lower holder; and the needle being exposed out of the sleeve.
摘要翻译：用于眼睛或身体纹身目的的安全针保持器，其提供针的可靠操作，防止针脱离其位置，并且避免着色剂回流由包含传动轴的上保持器，包含针的下保持器和连接两个上部和下部支架的中心支架; 在接近针的两端处的两个平面部分; 两个弹性构件各自插入到两个平坦部分的上方和下方; 套筒被插入到下支架的下端; 针头露出套筒。

9. 发明授权

US06386676B1 Reflective type media sensing methodology 失效
标题翻译：反射式媒体传感方法
公开(公告)号：US06386676B1
公开(公告)日：2002-05-14
申请号：US09757068
申请日：2001-01-08
申请人： Changguo Mike Yang , Chen Liu , Seng San Koh
发明人： Changguo Mike Yang , Chen Liu , Seng San Koh
IPC分类号： G01N2186
CPC分类号： B41J11/009 , B41J11/0095 , G01N21/55
摘要： A printer, which can detect a media sheet type, includes: a light emitting source and a reflector, the light emitting source being capable of emitting light in a light emission direction towards the reflector, the reflector being arranged in light emission direction and being capable of reflecting light emitted by the light emitting source in a light reflection direction; a detector being arranged such that it can detect reflected light; and a controller connected to the reflector, the controller being capable of modulating a characteristic of the reflected light.
摘要翻译：可以检测介质片类型的打印机包括：发光源和反射器，所述发光源能够沿着发光方向朝向反射器发射光，所述反射器被布置在发光方向上并且能够在光反射方向上反射由所述发光源发射的光; 检测器被布置成使得其可以检测反射光; 以及连接到所述反射器的控制器，所述控制器能够调制所述反射光的特性。

10. 发明申请

US20220075068A1 DECISION-BASED SENSOR FUSION WITH GLOBAL OPTIMIZATION FOR INDOOR MAPPING 有权
公开(公告)号：US20220075068A1
公开(公告)日：2022-03-10
申请号：US17472027
申请日：2021-09-10
申请人： Chen Liu , Zhiliu Yang , Shaoshan Liu
发明人： Chen Liu , Zhiliu Yang , Shaoshan Liu
IPC分类号： G01S17/89 , G05D1/02 , G01S15/86 , G01S17/58
摘要： A tightly coupled fusion approach that dynamically consumes light detection and ranging (LiDAR) and sonar data to generate reliable and scalable indoor maps for autonomous robot navigation. The approach may be used for the ubiquitous deployment of indoor robots that require the availability of affordable, reliable, and scalable indoor maps. A key feature of the approach is the utilization of a fusion mechanism that works in three stages: the first LiDAR scan matching stage efficiently generates initial key localization poses; a second optimization stage is used to eliminate errors accumulated from the previous stage and guarantees that accurate large-scale maps can be generated; and a final revisit scan fusion stage effectively fuses the LiDAR map and the sonar map to generate a highly accurate representation of the indoor environment.

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