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1. 发明授权

US07463033B2 NMR probe component with a gradient chip with a slot for insertion of a sample chip 有权
标题翻译： NMR探针组件，带有带插槽的样品芯片的梯度芯片
公开(公告)号：US07463033B2
公开(公告)日：2008-12-09
申请号：US11892316
申请日：2007-08-22
申请人： Charles Massin , Michael Fey , Schimun Denoth , Frank Vincent
发明人： Charles Massin , Michael Fey , Schimun Denoth , Frank Vincent
IPC分类号： G01V3/00
CPC分类号： G01R33/302 , G01R33/34092 , G01R33/341
摘要： A nuclear magnetic resonance (NMR) probe component, comprising a microfabricated planar gradient chip (1), with a substrate thickness dgc≦3 mm, carrying three micromachined planar partial gradient coils (10a-10f) on each of its two outer surfaces (12a, 13a), wherein the partial gradient coils (10a-10f) of the gradient chip (1) form a three-dimensional gradient system, wherein the gradient chip (1) has a central guiding and positioning slot (15) between the two outer surfaces (12a, 13a). The probe component also has a sample chip (2) for carrying an NMR sample at a sample location, with a microfabricated planar RF coil (21), wherein the sample chip (2) fits exactly in the guiding and positioning slot (15) such that in a measurement position, the sample location coincides with the center of the gradient system. The NMR probe component has improved spatial resolution and allows good alignment of the RF coil and the gradient system.
摘要翻译：一种核磁共振（NMR）探针组分，其包含微制造的平面梯度碎片（1），其基底厚度dgc <= 3mm，在其两个外表面的每一个上承载三个微加工平面部分梯度线圈（10a-10f）其中所述梯度芯片（1）的部分梯度线圈（10a-10f）形成三维梯度系统，其中所述梯度芯片（1）在所述梯度芯片（1）之间具有中心引导和定位槽（15）外表面（12a，13a）。探针组件还具有用于在样品位置携带NMR样品的样品芯片（2），其具有微制造的平面RF线圈（21），其中样品芯片（2）精确地配合在引导和定位槽（15）中，在测量位置，样本位置与梯度系统的中心重合。 NMR探针组件具有改进的空间分辨率，并且允许RF线圈和梯度系统的良好对准。

2. 发明申请

US20080068018A1 NMR probe component with a gradient chip with a slot for insertion of a sample chip 有权
标题翻译： NMR探针组件，带有带插槽的样品芯片的梯度芯片
公开(公告)号：US20080068018A1
公开(公告)日：2008-03-20
申请号：US11892316
申请日：2007-08-22
申请人： Charles Massin , Michael Fey , Schimun Denoth , Frank Vincent
发明人： Charles Massin , Michael Fey , Schimun Denoth , Frank Vincent
IPC分类号： G01R33/30
CPC分类号： G01R33/302 , G01R33/34092 , G01R33/341
摘要： A nuclear magnetic resonance (NMR) probe component, comprising a microfabricated planar gradient chip (1), with a substrate thickness dgc≦3 mm, carrying three micromachined planar partial gradient coils (10a-10f) on each of its two outer surfaces (12a, 13a), wherein the partial gradient coils (10a-10f) of the gradient chip (1) form a three-dimensional gradient system, wherein the gradient chip (1) has a central guiding and positioning slot (15) between the two outer surfaces (12a, 13a). The probe component also has a sample chip (2) for carrying an NMR sample at a sample location, with a microfabricated planar RF coil (21), wherein the sample chip (2) fits exactly in the guiding and positioning slot (15) such that in a measurement position, the sample location coincides with the center of the gradient system. The NMR probe component has improved spatial resolution and allows good alignment of the RF coil and the gradient system.
摘要翻译：一种核磁共振（NMR）探针组分，其包含具有衬底厚度d 3 g 3≤3mm的微制造平面梯度芯片（1），载有三个微加工平面部分梯度线圈（10a--10 f）在其两个外表面（12a，13a）中的每一个上，其中梯度芯片（1）的部分梯度线圈（10a-10f）形成三维梯度系统，其中梯度芯片）在两个外表面（12a，13a）之间具有中心引导和定位槽（15）。探针组件还具有用于在样品位置携带NMR样品的样品芯片（2），其具有微制造的平面RF线圈（21），其中样品芯片（2）精确地配合在引导和定位槽（15）中，在测量位置，样本位置与梯度系统的中心重合。 NMR探针组件具有改进的空间分辨率，并且允许RF线圈和梯度系统的良好对准。

3. 发明授权

US07612563B2 Flow-through microfluidic nuclear magnetic resonance(=NMR)-chip 有权
标题翻译：流通微流核磁共振（= NMR）芯片
公开(公告)号：US07612563B2
公开(公告)日：2009-11-03
申请号：US11905637
申请日：2007-10-03
申请人： Charles Massin , Michael Fey
发明人： Charles Massin , Michael Fey
IPC分类号： G01V3/00
CPC分类号： G01R33/302 , G01R33/307
摘要： A flow-through microfluidic NMR-chip comprising a substrate (5) which is planar in an yz-plane with a sample chamber (2) within the substrate (5), the sample chamber (2) being elongated and having walls which run parallel to the z-direction, the substrate (5) having a thickness in x-direction of a Cartesian xyz-coordinate system between 100 μm and 2 mm, and at least one planar receiving and/or transmission coil (1, 1′) with conductor sections (11) the coil (1, 1′) being arranged at least on one planar surface of the substrate (5), wherein the extension of the sample chamber (2) along the z-direction exceeds the extension of the coil (1) along the z-direction is characterized in that the extension of the coil (1, 1′) along the z-direction is larger than its extension along the y-direction. The inventive NMR-chip facilitated NMR-spectroscopic measurements with improved resolution, sensitivity as well as B1 homogeneity.
摘要翻译：一种流通微流体NMR芯片，包括在衬底（5）内具有样品室（2）的yz平面平面的衬底（5），样品室（2）是细长的并具有平行的壁在z方向上，基板（5）具有在100m和2mm之间的笛卡尔xyz坐标系的x方向上的厚度，以及至少一个平面接收和/或传输线圈（1,1'），具有导体部分（11），所述线圈（1,1'）布置在所述基板（5）的至少一个平坦表面上，其中所述样品室（2）沿着z方向的延伸超过所述线圈 1）沿着z方向的特征在于，线圈（1,1'）沿着z方向的延伸大于沿着y方向的延伸。本发明的NMR芯片促进了NMR光谱测量，具有改进的分辨率，灵敏度以及B1同质性。

4. 发明申请

US20080100296A1 Flow-through microfluidic nuclear magnetic resonance(=NMR)-chip 有权
标题翻译：流通微流核磁共振（= NMR）芯片
公开(公告)号：US20080100296A1
公开(公告)日：2008-05-01
申请号：US11905637
申请日：2007-10-03
申请人： Charles Massin , Michael Fey
发明人： Charles Massin , Michael Fey
IPC分类号： G01R33/30 , G01N24/08
CPC分类号： G01R33/302 , G01R33/307
摘要： A flow-through microfluidic NMR-chip comprising a substrate (5) which is planar in an yz-plane with a sample chamber (2) within the substrate (5), the sample chamber (2) being elongated and having walls which run parallel to the z-direction, the substrate (5) having a thickness in x-direction of a Cartesian xyz-coordinate system between 100 μm and 2 mm, and at least one planar receiving and/or transmission coil (1, 1′) with conductor sections (11) the coil (1, 1′) being arranged at least on one planar surface of the substrate (5), wherein the extension of the sample chamber (2) along the z-direction exceeds the extension of the coil (1) along the z-direction is characterized in that the extension of the coil (1, 1′) along the z-direction is larger than its extension along the y-direction. The inventive NMR-chip facilitated NMR-spectroscopic measurements with improved resolution, sensitivity as well as B1 homogeneity.
摘要翻译：一种流通微流体NMR芯片，包括在衬底（5）内具有样品室（2）的yz平面平面的衬底（5），样品室（2）是细长的并具有平行的壁在z方向上，基板（5）具有在100m和2mm之间的笛卡尔xyz坐标系的x方向上的厚度，以及至少一个平面接收和/或传输线圈（1,1'），具有导体部分（11），所述线圈（1,1'）布置在所述基板（5）的至少一个平坦表面上，其中所述样品室（2）沿着z方向的延伸超过所述线圈 1）沿着z方向的特征在于，线圈（1,1'）沿着z方向的延伸大于沿着y方向的延伸。本发明的NMR芯片促进了NMR光谱测量，具有改进的分辨率，灵敏度以及B1同质性。

5. 发明申请

US20130327124A1 METHOD FOR SETTING A TEMPERATURE OF A SENSOR ELEMENT 有权
标题翻译：设置传感器元件温度的方法
公开(公告)号：US20130327124A1
公开(公告)日：2013-12-12
申请号：US13877448
申请日：2011-09-23
申请人： Jens Schneider , Michael Fey , Ingmar Burak , Markus Riemann , Reinhard Hamann
发明人： Jens Schneider , Michael Fey , Ingmar Burak , Markus Riemann , Reinhard Hamann
IPC分类号： G01N25/18
CPC分类号： G01N25/18 , F01N11/007 , F01N2560/20 , G01N27/4067 , G05D23/24 , Y02T10/47
摘要： A method for setting a temperature of a sensor element, which is heatable with the aid of a heating device, for detecting at least one property of a gas in a measuring gas chamber includes at least one regulation of the heating device, the regulation including: (a) detecting at least one actual value of at least one controlled variable of the sensor element, (b) ascertaining a setpoint value of the at least one controlled variable, (c) generating at least one manipulated variable of the heating device with the aid of a comparison of the setpoint value and the actual value, and (d) in a monitoring step, checking at least one parameter used to set the temperature, and the at least one manipulated variable being influenced as a function of the check.
摘要翻译：用于设置用于检测测量气体室中的气体的至少一种性质的用于借助于加热装置可加热的传感器元件的温度的方法包括加热装置的至少一个限制，所述调节包括：（a）检测所述传感器元件的至少一个受控变量的至少一个实际值，（b）确定所述至少一个受控变量的设定点值，（c）产生所述加热装置的至少一个操纵变量，有助于比较设定点值和实际值，以及（d）在监视步骤中，检查至少一个用于设置温度的参数，以及至少一个受控变量作为检查的函数而受到影响。

6. 发明申请

US20080106263A1 Sample holder for NMR measurements with field homogenization in the sample volume by means of the bordering surfaces of the sample holder 有权
标题翻译：用于通过样品架的边界表面在样品体积中进行现场均匀化的NMR测量的样品架
公开(公告)号：US20080106263A1
公开(公告)日：2008-05-08
申请号：US11907417
申请日：2007-10-12
申请人： Michael Fey , Thomas Speck
发明人： Michael Fey , Thomas Speck
IPC分类号： G01R33/30
CPC分类号： G01R33/30 , G01R33/56536
摘要： A sample vessel (80) made of material with magnetic susceptibility χ2, for containing a sample substance (87) with magnetic susceptibility χ3≠χ2 to be analyzed in a nuclear magnetic resonance (NMR) spectrometer, has an inner interface G2 toward the sample substance and an outer interface G1 toward the environment (85) that exhibits magnetic susceptibility χ1. The shape of the interface toward the sample substance and the interface toward the environment are coordinated to match the discontinuities in susceptibility at the interfaces in such a way that on introduction of the sample tube filled with sample substance into the previously homogeneous magnetic field of an NMR spectrometer, the magnetic field inside the sample substance remains largely homogeneous.
摘要翻译：由具有磁化率的材料制成的样品容器（80）用于容纳具有磁化率的样品物质（87），其具有磁化率ki < 在核磁共振（NMR）光谱仪中进行分析时，具有朝向样品物质的内部界面G 2 2和朝向环境的外部界面G 1（＆lt; 1＆gt; 85），其显示磁化率为1/2。配合朝向样品物质的界面的形状和朝向环境的界面进行协调以匹配界面处的敏感性的不连续性，使得在将样品物质填充到先前均匀的NMR磁场中的样品管光谱仪，样品物质内的磁场保持很大程度上均匀。

7. 发明授权

US4549474A Air conditioner outlet 失效
标题翻译：空调出口
公开(公告)号：US4549474A
公开(公告)日：1985-10-29
申请号：US618501
申请日：1984-06-08
申请人： Michael Fey , Wolfgang Finkelstein , Josef Haaz , Hans Riegel
发明人： Michael Fey , Wolfgang Finkelstein , Josef Haaz , Hans Riegel
IPC分类号： F24F11/76 , F24F13/06 , G05D23/20 , F24F13/08
CPC分类号： G05D23/20 , F24F11/053 , F24F13/06
摘要： A floor outlet for an air conditioner has a grill which is formed by ring elements whose radial connecting ribs are inclined to impart a vortex flow to the emerging air. A central baffle body is constituted by a disc and a multiplicity of angularly equispaced radially extending blades twisted out of the plane of the disc and projecting therefrom.
摘要翻译：用于空调的地板出口具有格栅，该格栅由环形元件形成，其径向连接肋倾斜以向出现的空气施加涡流。中央挡板体由盘和多个角度均匀的径向延伸的叶片构成，该叶片从盘的平面扭转出并从其突出。

8. 发明授权

US09222852B2 Method for detecting the operational readiness of a jump lambda sensor 有权
标题翻译：用于检测跳跃式λ传感器的操作准备的方法
公开(公告)号：US09222852B2
公开(公告)日：2015-12-29
申请号：US13995020
申请日：2011-11-23
申请人： Michael Fey
发明人： Michael Fey
IPC分类号： G01M15/10 , F02D41/14
CPC分类号： G01M15/104 , F02D41/1455 , F02D41/1496 , Y02T10/47
摘要： In a method for detecting the operational readiness of a jump lambda sensor associated with an internal combustion engine the internal resistance of the sensor is determined as the criterion for the operational readiness of the sensor. The internal resistance is measured by applying a pulsed current to the sensor, the frequency of the current being selected as a function of the state of the sensor (1, 2, 3, 4).
摘要翻译：在用于检测与内燃机相关联的跳跃式λ传感器的操作准备状态的方法中，传感器的内部电阻被确定为传感器的操作准备的标准。通过向传感器施加脉冲电流来测量内部电阻，根据传感器（1,2,3,4）的状态选择电流的频率。

9. 发明申请

US20130271141A1 MULTIPLE RESONANCE SAMPLE COIL FOR MAGIC ANGLE SPINNING NMR PROBE 有权
标题翻译：用于魔术角旋转核磁共振探测器的多个共振样品盘
公开(公告)号：US20130271141A1
公开(公告)日：2013-10-17
申请号：US13447189
申请日：2012-04-14
申请人： Wurong Zhang , Michael Fey , Peter Gor'kov
发明人： Wurong Zhang , Michael Fey , Peter Gor'kov
IPC分类号： G01R33/34
CPC分类号： G01R33/34092 , G01R33/34053 , G01R33/34061 , G01R33/34076 , G01R33/3635
摘要： A multiple resonance sample coil for a magic angle spinning nuclear magnetic resonance probe is comprised of a solenoid coil that resonates at low frequencies and a resonator that resonates at high frequencies. The ends of the low frequency solenoid coil are electrically connected to the high frequency resonator to eliminate arcing and allow the solenoid coil to extend the full width of the resonator. In some embodiments, the high frequency resonator is constructed from the outermost turns of the solenoid coil in the form of a birdcage resonator. In another embodiment, the solenoid coil is electrically connected to one turn of the resonator and the other turn is used as part of a trap to shunt the resonator at low frequencies.
摘要翻译：用于魔角旋转核磁共振探测器的多重谐振采样线圈由在低频谐振的螺线管线圈和在高频下共振的谐振器构成。低频螺线管线圈的端部电连接到高频谐振器以消除电弧并允许螺线管线圈延伸谐振器的全部宽度。在一些实施例中，高频谐振器由鸟笼式谐振器形式的螺线管线圈的最外圈构成。在另一个实施例中，螺线管线圈电连接到谐振器的一匝，而另一匝用作陷波器的一部分以在低频下分流谐振器。

10. 发明申请

US20130263652A1 METHOD FOR DETECTING THE OPERATIONAL READINESS OF A JUMP LAMBDA SENSOR 有权
标题翻译：用于检测JAMM LAMBDA传感器的操作准确性的方法
公开(公告)号：US20130263652A1
公开(公告)日：2013-10-10
申请号：US13995020
申请日：2011-11-23
申请人： Michael Fey
发明人： Michael Fey
IPC分类号： G01M15/10
CPC分类号： G01M15/104 , F02D41/1455 , F02D41/1496 , Y02T10/47
摘要： In a method for detecting the operational readiness of a jump lambda sensor associated with an internal combustion engine the internal resistance of the sensor is determined as the criterion for the operational readiness of the sensor. The internal resistance is measured by applying a pulsed current to the sensor, the frequency of the current being selected as a function of the state of the sensor (1, 2, 3, 4).
摘要翻译：在用于检测与内燃机相关联的跳跃式λ传感器的操作准备状态的方法中，传感器的内部电阻被确定为传感器的操作准备的标准。通过向传感器施加脉冲电流来测量内部电阻，根据传感器（1,2,3,4）的状态选择电流的频率。

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