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1. 发明申请

US20050215892A1 System and method for transducer array cooling through forced convection 审中-公开
标题翻译：通过强制对流传感器阵列冷却的系统和方法
公开(公告)号：US20050215892A1
公开(公告)日：2005-09-29
申请号：US10805783
申请日：2004-03-22
申请人： Charles Emery , Zoran Banjanin , Chi-Yin Lee , Alampallam Ramachandran , John Dennis
发明人： Charles Emery , Zoran Banjanin , Chi-Yin Lee , Alampallam Ramachandran , John Dennis
IPC分类号： A61B8/00 , A61B8/06 , G10K11/00
CPC分类号： A61B8/546 , A61B8/00 , A61B8/4472 , A61B2562/187 , G10K11/004
摘要： A system and method for cooling an entirely or partially immersed mechanical or other type of transducer array is disclosed. Motion/flow of the immersion fluid is induced either by motion of the mechanical transducer itself, where the transducer is of the mechanically movable type, or by a separate motion-inducing mechanism located in or coupled with the fluid-filled, or partially filled, array housing. The resultant fluid flow/motion increases, i.e. more efficiently utilizes, the thermal carrying capacity of the immersion fluid by more uniformly distributing the thermal energy convected from the transducer array throughout the fluid volume. This results in an improved ability to cool the transducer array. The disclosed cooling system and method may be used in such a way so as to not substantially inhibit operation of the transducer array.
摘要翻译：公开了一种用于冷却全部或部分浸没的机械或其他类型的换能器阵列的系统和方法。浸没流体的运动/流动是通过机械传感器本身的运动引起的，其中换能器是可机械移动的，或者通过位于流体填充或部分填充的或与部分填充的流体相连接的单独的运动诱导机构，阵列外壳。通过更均匀地将从换能器阵列对流的热能更均匀地分布在整个流体体积中，所产生的流体流动/运动增加，即更有效地利用浸入流体的热载运能力。这样可以提高冷却换能器阵列的能力。所公开的冷却系统和方法可以以这样的方式使用，以便基本上不能抑制换能器阵列的操作。

2. 发明申请

US20120059259A1 SYSTEM AND METHOD FOR TREATING A THERAPEUTIC SITE 有权
标题翻译：治疗疗法的系统和方法
公开(公告)号：US20120059259A1
公开(公告)日：2012-03-08
申请号：US13245703
申请日：2011-09-26
申请人： Charles Emery , Larry Augustine , Robyn Lahman , David M. Perozek , Jimin Zhang
发明人： Charles Emery , Larry Augustine , Robyn Lahman , David M. Perozek , Jimin Zhang
IPC分类号： A61N7/00 , A61B6/00
CPC分类号： A61B8/0833 , A61B5/026 , A61B8/0841 , A61B8/12 , A61B8/4405 , A61B8/445 , A61B17/0057 , A61B18/02 , A61B34/25 , A61B50/13 , A61B2017/00557 , A61B2017/00637 , A61B2017/00641 , A61B2090/372 , A61B2090/3784 , A61B2090/3929 , A61B2090/3958 , A61B2090/397 , A61F2/82 , A61M25/10 , A61N7/02
摘要： A targeting catheter is used to locate an arteriotomy, such as is formed during a femoral artery catheterization procedure. The targeting catheter includes one or more targeting aids, such as an inflatable balloon or sensor (e.g., Doppler or temperature sensor), to locate the arteriotomy. The targeting aid may be positioned at the arteriotomy. An ultrasonic beacon on the catheter may then be located relative to a therapeutic ultrasonic applicator (e.g., by using acoustic time-of-flight) so that the focus of ultrasonic energy from the applicator can be aligned with the arteriotomy.
摘要翻译：靶向导管用于定位动脉切开术，例如在股动脉插管术过程中形成的。靶向导管包括一个或多个靶向辅助器，例如可充气球囊或传感器（例如，多普勒或温度传感器），以定位动脉切开术。靶向助剂可以位于动脉切开术。然后可以相对于治疗性超声波施加器（例如，通过使用声学飞行时间）来定位导管上的超声波信标，使得来自施用器的超声能量的焦点可以与动脉切开术对准。

3. 发明申请

US20070239000A1 Systems and methods for ultrasound applicator station keeping 有权
标题翻译：超声波给药站保持系统和方法
公开(公告)号：US20070239000A1
公开(公告)日：2007-10-11
申请号：US11583569
申请日：2006-10-19
申请人： Charles Emery , Larry Augustine , Robyn Lahman , David Perozek , Jimin Zhang
发明人： Charles Emery , Larry Augustine , Robyn Lahman , David Perozek , Jimin Zhang
IPC分类号： A61B8/00
CPC分类号： A61B8/0833 , A61B5/026 , A61B8/0841 , A61B8/12 , A61B8/4405 , A61B8/445 , A61B17/0057 , A61B18/02 , A61B34/25 , A61B50/13 , A61B2017/00557 , A61B2017/00637 , A61B2017/00641 , A61B2090/372 , A61B2090/3784 , A61B2090/3929 , A61B2090/3958 , A61B2090/397 , A61F2/82 , A61M25/10 , A61N7/02
摘要： Systems and methods for maintaining the alignment of a therapeutic ultrasound applicator to a target site are described. Overlapping ultrasound signals are sent to a target tissue site and the echo detected. An algorithm is described for detecting tissue movement relative to the applicator based on comparison of the echo with a previously stored echo.
摘要翻译：描述了用于将治疗性超声波施加器对准到目标部位的系统和方法。重叠的超声信号被发送到目标组织位点，并且检测到回声。描述了一种用于基于回波与先前存储的回波的比较来检测相对于施用器的组织运动的算法。

4. 发明申请

US20070194658A1 Systems and methods for performing acoustic hemostasis of deep bleeding trauma in limbs 审中-公开
公开(公告)号：US20070194658A1
公开(公告)日：2007-08-23
申请号：US11486528
申请日：2006-07-13
申请人： Jimin Zhang , David Perozek , John Kook , Ed Caldwell , Charles Emery , Robert Pedersen
发明人： Jimin Zhang , David Perozek , John Kook , Ed Caldwell , Charles Emery , Robert Pedersen
IPC分类号： H01L41/09
CPC分类号： A61B8/4227 , A61B5/445 , A61B8/06 , A61B8/4281 , A61B8/4483 , A61B17/1325 , A61B17/135 , A61N7/02 , A61N2007/0078
摘要： An inflatable cuff having integrated ultrasound transducers is used to effect hemostasis of deep bleeding wounds in limbs. The cuff includes a chamber defined by a bladder or a series of dams into which a fluid may be introduced and pressurized. The pressure of the fluid stops or slows bleeding while high intensity focused ultrasound is applied to effect hemostasis. The fluid may also serve as an acoustic couplant between the limb and the ultrasound transducers. The transducers may be electrostrictive transducers. Diodes may be used to reduce parallel capacitive loading in the transducer array. Bypass capacitors using the electrostrictive material may also be used.

5. 发明授权

US06402693B1 Ultrasonic transducer aligning system to replicate a previously obtained image 有权
标题翻译：超声波换能器对准系统来复制先前获得的图像
公开(公告)号：US06402693B1
公开(公告)日：2002-06-11
申请号：US09482744
申请日：2000-01-13
申请人： Charles Emery
发明人： Charles Emery
IPC分类号： A61B800
CPC分类号： A61B8/00
摘要： To aid a physician or sonographer in replicating an image of tissue sample, an ultrasound machine performs a comparison of ultrasound images with a stored reference image. The results of the comparison are provided to a user in a visual or audible form to allow the user to alter the position of the transducer to substantially match the position used to acquire the reference image.
摘要翻译：为了帮助医师或超声医师复制组织样本的图像，超声机器执行超声图像与存储的参考图像的比较。比较的结果以视觉或听觉形式提供给用户，以允许用户改变换能器的位置，以与用于获取参考图像的位置基本匹配。

6. 发明申请

US20110230796A1 SYSTEM AND METHOD FOR TREATING A THERAPEUTIC SITE 审中-公开
标题翻译：治疗疗法的系统和方法
公开(公告)号：US20110230796A1
公开(公告)日：2011-09-22
申请号：US13118245
申请日：2011-05-27
申请人： Charles Emery , Larry Augustine , Robyn Lahman , David M. Perozek , Jimin Zhang
发明人： Charles Emery , Larry Augustine , Robyn Lahman , David M. Perozek , Jimin Zhang
IPC分类号： A61N7/00
CPC分类号： A61B8/0833 , A61B5/026 , A61B8/0841 , A61B8/12 , A61B8/4405 , A61B8/445 , A61B17/0057 , A61B18/02 , A61B34/25 , A61B50/13 , A61B2017/00557 , A61B2017/00637 , A61B2017/00641 , A61B2090/372 , A61B2090/3784 , A61B2090/3929 , A61B2090/3958 , A61B2090/397 , A61F2/82 , A61M25/10 , A61N7/02
摘要： A targeting catheter is used to locate an arteriotomy, such as is formed during a femoral artery catheterization procedure. The targeting catheter includes one or more targeting aids, such as an inflatable balloon or sensor (e.g., Doppler or temperature sensor), to locate the arteriotomy. The targeting aid may be positioned at the arteriotomy. An ultrasonic beacon on the catheter may then be located relative to a therapeutic ultrasonic applicator (e.g., by using acoustic time-of-flight) so that the focus of ultrasonic energy from the applicator can be aligned with the arteriotomy.
摘要翻译：靶向导管用于定位动脉切开术，例如在股动脉插管术过程中形成的。靶向导管包括一个或多个靶向辅助器，例如可充气球囊或传感器（例如，多普勒或温度传感器），以定位动脉切开术。靶向助剂可以位于动脉切开术。然后可以相对于治疗性超声波施加器（例如，通过使用声学飞行时间）来定位导管上的超声波信标，使得来自施用器的超声能量的焦点可以与动脉切开术对准。

7. 发明申请

US20110230763A1 SYSTEM AND METHOD FOR TREATING A THERAPEUTIC SITE 审中-公开
公开(公告)号：US20110230763A1
公开(公告)日：2011-09-22
申请号：US13118144
申请日：2011-05-27
申请人： Charles Emery , Larry Augustine , Robyn Lahman , David M. Perozek , Jimin Zhang
发明人： Charles Emery , Larry Augustine , Robyn Lahman , David M. Perozek , Jimin Zhang
IPC分类号： A61B8/00 , A61N7/00
CPC分类号： A61B8/0833 , A61B5/026 , A61B8/0841 , A61B8/12 , A61B8/4405 , A61B8/445 , A61B17/0057 , A61B18/02 , A61B34/25 , A61B50/13 , A61B2017/00557 , A61B2017/00637 , A61B2017/00641 , A61B2090/372 , A61B2090/3784 , A61B2090/3929 , A61B2090/3958 , A61B2090/397 , A61F2/82 , A61M25/10 , A61N7/02
摘要： A targeting catheter is used to locate an arteriotomy, such as is formed during a femoral artery catheterization procedure. The targeting catheter includes one or more targeting aids, such as an inflatable balloon or sensor (e.g., Doppler or temperature sensor), to locate the arteriotomy. The targeting aid may be positioned at the arteriotomy. An ultrasonic beacon on the catheter may then be located relative to a therapeutic ultrasonic applicator (e.g., by using acoustic time-of-flight) so that the focus of ultrasonic energy from the applicator can be aligned with the arteriotomy.

8. 发明授权

US09220488B2 System and method for treating a therapeutic site 有权
标题翻译：用于治疗治疗部位的系统和方法
公开(公告)号：US09220488B2
公开(公告)日：2015-12-29
申请号：US13618361
申请日：2012-09-14
申请人： Charles Emery , Larry Augustine , Robyn Lahman , David M. Perozek , Jimin Zhang
发明人： Charles Emery , Larry Augustine , Robyn Lahman , David M. Perozek , Jimin Zhang
IPC分类号： A61B8/13 , A61B17/00 , A61B8/08 , A61B8/12 , A61F2/82 , A61N7/02 , A61B5/026 , A61B8/00 , A61B18/02 , A61B19/00 , A61B19/02 , A61M25/10
CPC分类号： A61B8/0833 , A61B5/026 , A61B8/0841 , A61B8/12 , A61B8/4405 , A61B8/445 , A61B17/0057 , A61B18/02 , A61B34/25 , A61B50/13 , A61B2017/00557 , A61B2017/00637 , A61B2017/00641 , A61B2090/372 , A61B2090/3784 , A61B2090/3929 , A61B2090/3958 , A61B2090/397 , A61F2/82 , A61M25/10 , A61N7/02
摘要： A targeting catheter is used to locate an arteriotomy, such as is formed during a femoral artery catheterization procedure. The targeting catheter includes one or more targeting aids, such as an inflatable balloon or sensor (e.g., Doppler or temperature sensor), to locate the arteriotomy. The targeting aid may be positioned at the arteriotomy. An ultrasonic beacon on the catheter may then be located relative to a therapeutic ultrasonic applicator (e.g., by using acoustic time-of-flight) so that the focus of ultrasonic energy from the applicator can be aligned with the arteriotomy.
摘要翻译：靶向导管用于定位动脉切开术，例如在股动脉插管术过程中形成的。靶向导管包括一个或多个靶向辅助器，例如可充气球囊或传感器（例如，多普勒或温度传感器），以定位动脉切开术。靶向助剂可以位于动脉切开术。然后可以相对于治疗性超声波施加器（例如，通过使用声学飞行时间）来定位导管上的超声波信标，使得来自施用器的超声能量的焦点可以与动脉切开术对准。

9. 发明申请

US20120109023A1 SYSTEMS AND METHODS TO TARGET BLOOD VESSEL ADVENTITIA WITH TRANSCUTANEOUS FOCUSED ULTRASOUND 审中-公开
标题翻译：具有超声聚焦超声的目标血管血管的系统和方法
公开(公告)号：US20120109023A1
公开(公告)日：2012-05-03
申请号：US13344417
申请日：2012-01-05
申请人： Charles Emery , Larry Augustine , Robyn Lahman , David M. Perozek , Jimin Zhang
发明人： Charles Emery , Larry Augustine , Robyn Lahman , David M. Perozek , Jimin Zhang
IPC分类号： A61N7/00
CPC分类号： A61B8/0833 , A61B5/026 , A61B8/0841 , A61B8/12 , A61B8/4405 , A61B8/445 , A61B17/0057 , A61B18/02 , A61B34/25 , A61B50/13 , A61B2017/00557 , A61B2017/00637 , A61B2017/00641 , A61B2090/372 , A61B2090/3784 , A61B2090/3929 , A61B2090/3958 , A61B2090/397 , A61F2/82 , A61M25/10 , A61N7/02
摘要： Systems and methods for maintaining the alignment of a therapeutic ultrasound applicator to a target site are described. Overlapping ultrasound signals are sent to a target tissue site and the echo detected. An algorithm is described for detecting tissue movement relative to the applicator based on comparison of the echo with a previously stored echo.
摘要翻译：描述了用于将治疗性超声波施加器对准到目标部位的系统和方法。重叠的超声信号被发送到目标组织位点，并且检测到回声。描述了一种用于基于回波与先前存储的回波的比较来检测相对于施用器的组织运动的算法。

10. 发明申请

US20080249419A1 TIME-OF-FLIGHT TRIANGULATION BASED METHODS OF DEVICE SPATIAL REGISTRATION FOR MULTIPLE-TRANSDUCER THERAPEUTIC ULTRASOUND SYSTEMS 审中-公开
标题翻译：基于时空三角法的多传感器治疗超声系统设备空间注册方法
公开(公告)号：US20080249419A1
公开(公告)日：2008-10-09
申请号：US11955310
申请日：2007-12-12
申请人： K. Michael Sekins , Charles Emery
发明人： K. Michael Sekins , Charles Emery
IPC分类号： A61B8/00
CPC分类号： A61N7/02 , A61B8/08 , A61B8/4227 , A61B8/4483 , A61B2017/00106 , A61B2090/378 , A61N2007/0078
摘要： Embodiments disclosed herein relate to a therapeutic ultrasound device spatial registration method and apparatus. The method enables locating a tissue target and surrounding tissue structures affecting the available acoustic beam paths to the target, relative to each individual therapeutic and diagnostic (e.g., imaging) transducer, in a device comprising a plurality of such transducers. By locating the target and tissue structures relative to each therapeutic transducer and/or array (e.g., in “local” coordinates) assists in transforming the locations relative to any transducers, enabling determination of which therapeutic transducers to use to treat the target, and specification of their respective ultrasound powers or energy, focal locations and beam patterns. The registration method employs a plurality of emitter and receiver acoustic sensors on, respectively, a plurality of imaging and therapeutic transducer device panels.
摘要翻译：本文公开的实施例涉及治疗性超声装置空间配准方法和装置。该方法使得能够在包括多个这种换能器的装置中相对于每个单独的治疗和诊断（例如，成像）换能器定位影响到目标的可用声束路径的组织靶和周围组织结构。通过相对于每个治疗换能器和/或阵列（例如，在“局部”坐标）中定位目标和组织结构有助于相对于任何换能器转换位置，能够确定用于治疗靶的哪些治疗传感器，以及规范其各自的超声功率或能量，焦点位置和波束图案。登记方法分别在多个成像和治疗换能器装置面板上使用多个发射器和接收器声学传感器。

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