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1. 发明授权

US3934222A Terrain closure warning system with climb inhibit and altitude gain measurement 失效
标题翻译：地形闭合预警系统，具有爬升抑制和高度增益测量
公开(公告)号：US3934222A
公开(公告)日：1976-01-20
申请号：US564512
申请日：1975-04-02
申请人： Charles Donald Bateman , Hans Rudolf Muller , Frank Joseph Brem
发明人： Charles Donald Bateman , Hans Rudolf Muller , Frank Joseph Brem
IPC分类号： B64D45/04 , G01C5/00 , G01C5/06 , G01C21/00 , G01C21/20 , G01L7/12 , G01S19/14 , G05D1/04 , G08G5/02
CPC分类号： G01C5/005 , G05D1/0607
摘要： In a terrain warning system wherein the rate of the aircraft's closure to the terrain is compared to the aircraft's altitude above the terrain in order to generate a warning signal for excessive closure rates, a circuit is provided to inhibit the warning signal when the aircraft begins to climb in response to the warning signal and to measure the altitude gained by the aircraft resulting in the reactivation of the warning signal if the aircraft has leveled off before gaining a predetermined amount of altitude. The circuit includes: a memory element to indicate that a warning signal has been generated; a circuit to generate a climb signal in response to a barometric rate of change signal indicating the aircraft is climbing; and an integrating circuit responsive to the barometric rate signal to determine the amount of altitude the aircraft has gained while climbing. If the aircraft has not gained the predetermined amount of altitude before leveling off, as indicated by the climb signal, the memory element will reactivate the warning signal.
摘要翻译：在地形警告系统中，其中将飞机关闭到地形的速率与飞机在地形上方的高度进行比较，以便产生用于过度关闭速率的警告信号，提供电路以在飞行器开始时抑制警告信号在响应警告信号的情况下爬升并测量飞机获得的高度，导致如果飞机在获得预定量的高度之前已经平整，则重新激活警告信号。电路包括：用于指示已经产生警告信号的存储元件; 响应于指示飞机的气压变化信号而产生爬升信号的电路正在攀爬; 以及响应于气压信号的积分电路，以确定飞机在爬升时获得的高度。如果飞机在平整之前没有获得预定的高度，如爬升信号所示，则存储元件将重新激活警告信号。

2. 发明授权

US3934221A Terrain closure warning system with altitude rate signal conditioning 失效
标题翻译：地形闭合报警系统，具有高度信号调理功能
公开(公告)号：US3934221A
公开(公告)日：1976-01-20
申请号：US556022
申请日：1975-03-06
申请人： Charles Donald Bateman , Hans Rudolf Muller
发明人： Charles Donald Bateman , Hans Rudolf Muller
IPC分类号： B64D45/04 , G01C5/00 , G01C21/00 , G01C21/20 , G05D1/06 , G08G5/02
CPC分类号： G01C5/005 , G05D1/0607
摘要： In an aircraft terrain warning system utilizing a radar altimeter wherein the rate of closure to the terrain is compared with the aircraft's altitude above the terrain to generate a warning signal when the closure rate is excessive for a particular altitude, the closure rate signal is limited and biased depending upon the aircraft's closure rate and configuration in order to significantly increase the time response of the system while at the same time reducing nuisance warnings. The amplitude limit on the closure rate signal, is varied, above a predefined altitude, as a function of the closure rate signal in oreder to provide increased warning times at greater closure rates. Circuitry, responsive to the aircraft's flap positions, is also provided to alter the characteristics of rate limiter so as to provide warning parameters that more accurately reflect operating conditions at lower aircraft speeds.
摘要翻译：在使用雷达高度计的飞机地形预警系统中，当对于特定高度的闭合速率过大时，与地形的关闭速率与飞机在地形上方的高度进行比较以产生警告信号，闭合速率信号受到限制，这取决于飞机的关闭速率和配置，以便显着增加系统的时间响应，同时减少麻烦警告。关闭速率信号的幅度限制在预定高度以上，作为关闭速率信号的函数而变化，以在更大的闭合速率下提供增加的警告时间。还提供了响应于飞机的襟翼位置的电路，以改变速率限制器的特性，以便提供更准确地反映较低飞行器速度下的操作条件的警告参数。

3. 发明授权

US3947810A Negative climb rate after take-off warning system with predetermined loss of altitude inhibit 失效
标题翻译：起飞警报系统的负爬升率预先设定了高度的失去抑制
公开(公告)号：US3947810A
公开(公告)日：1976-03-30
申请号：US540477
申请日：1975-01-22
申请人： Charles Donald Bateman , Hans Rudolf Muller
发明人： Charles Donald Bateman , Hans Rudolf Muller
IPC分类号： B64D45/04 , G01C5/00 , G01C21/00 , G01C21/20 , G01S13/91 , G05D1/06 , G08G5/04
CPC分类号： G01C5/005 , G05D1/0607
摘要： In a warning system for aircraft that generates a warning signal when the aircraft is descending during a take-off or missed approach phase of operation, the warning is inhibited for a predetermined loss of altitude in order to allow the aircraft to descend a short distance without triggering a nuisance warning. Specifically, a circuit is provided to integrate a signal representing the aircraft's rate of descent until the integrated signal is equal to a predetermined drop in altitude whereupon the warning signal is triggered.
摘要翻译：在飞机的警报系统中，当飞机在起飞或未接近运行阶段下降时，会产生警告信号，警告将被禁止预定的高度损失，以便允许飞机下降很短的距离，而不会引发滋扰警告。具体地，提供电路以集成表示飞行器下降率的信号，直到积分信号等于预定的高度下降，由此触发警告信号。

4. 发明授权

US3958219A Terrain closure warning system with altitude rate signal conditioning 失效
标题翻译：带雷达信号信号调理的TERRAIN闭合警告系统
公开(公告)号：US3958219A
公开(公告)日：1976-05-18
申请号：US596943
申请日：1975-07-18
申请人： Charles Donald Bateman , Hans Rudolf Muller
发明人： Charles Donald Bateman , Hans Rudolf Muller
IPC分类号： G01C5/00 , G05D1/06
CPC分类号： G01C5/005 , G05D1/0607
摘要： In an aircraft terrain warning system utilizing a radar altimeter wherein the rate of closure to the terrain is compared with the aircraft's altitude above the terrain to generate a warning signal when the closure rate is excessive for a particular altitude, the closure rate signal is limited and biased depending upon the aircraft's closure rate and configuration in order to significantly increase the time response of the system while at the same time reducing nuisance warnings. The amplitude limit on the closure rate signal is varied, above a predefined altitude, as a function of the closure rate signal in order to provide increased warning times at greater closure rates. Circuitry, responsive to the aircraft's flap positions, is also provided to alter the characteristics of rate limiter so as to provide warning parameters that more accurately reflect operating conditions at lower aircraft speeds.

5. 发明授权

US4095271A Aircraft pitch attitude signal generator 失效
标题翻译：飞机倾斜姿态信号发生器
公开(公告)号：US4095271A
公开(公告)日：1978-06-13
申请号：US789153
申请日：1977-04-20
申请人： Hans Rudolf Muller
发明人： Hans Rudolf Muller
IPC分类号： G01C21/10 , B64D43/00 , G01C9/00 , G01C19/44 , G05D1/06 , G06G7/78
CPC分类号： G05D1/0607 , G01C19/44 , G01C9/005 , G06G7/78
摘要： In order to provide a more accurate representation of aircraft pitch attitude for use in aircraft head up display devices, a circuit for generating a computed pitch signal responds to a longitudinal accelerometer and a vertical gyroscope within the aircraft wherein the computed pitch signal is generated by adding to the gyro pitch signal a correction factor computed by subtracting the value of the computed pitch signal from an inertial pitch signal derived from the longitudinal accelerometer. In order to compensate for the effects of aircraft acceleration on the longitudinal accelerometer signal, a computed acceleration signal derived from the difference between the longitudinal accelerometer signal and the gyro pitch signal is subtracted from the longitudinal accelerometer to generate the inertial pitch signal. To further compensate the systems for long term errors in the gyro pitch signal, the combined longitudinal acceleration and gyro pitch signal is subtracted from a differentiated air speed signal and the resulting difference signal is integrated over time to generate an acceleration correction signal that is applied to the computed acceleration signal.

6. 发明授权

US4057782A Low altitude head up display for aircraft 失效
标题翻译：飞机低空抬头显示
公开(公告)号：US4057782A
公开(公告)日：1977-11-08
申请号：US673794
申请日：1976-04-05
申请人： Hans Rudolf Muller
发明人： Hans Rudolf Muller
IPC分类号： B64D45/08 , B64C13/18 , G01C23/00 , G02B27/01 , G02B27/02 , G05D1/06
CPC分类号： G05D1/0676 , G01C23/005 , G02B27/01
摘要： An aircraft instrument with a reflective screen on which the pilot views a collimated head up display of flight guidance information against a background of the outside world, for low altitude maneuvers. The guidance information includes a pitch stabilized reference indicia and a flight path indicia. The pitch reference and flight path indicia are positioned on the screen in accordance with aircraft operating parameters and pilot inputs to provide for a flare maneuver to touchdown or to direct the pilot in a path parallel with the surface of the ground, as for ejecting cargo.
摘要翻译：具有反射屏幕的飞行器乐器，飞行员在其上观看飞行指导信息的准直头部显示，以便在外部世界的背景下进行低空演习。引导信息包括俯仰稳定的参考标记和飞行路径标记。俯仰参考和飞行路线标记根据飞行器操作参数和飞行员输入位于屏幕上，以提供火炬机动触地或引导飞行员平行于地面的路径，以便排出货物。

7. 发明授权

US3967799A Head up display and pitch generator 失效
标题翻译：抬头显示和俯仰发生器
公开(公告)号：US3967799A
公开(公告)日：1976-07-06
申请号：US527044
申请日：1974-11-25
申请人： Hans Rudolf Muller
发明人： Hans Rudolf Muller
IPC分类号： G01C9/00 , G02B27/00 , G02B27/01 , G05D1/06 , B64C13/18 , G05D1/08
CPC分类号： G02B27/01 , G01C9/005 , G05D1/0676 , G02B2027/0154 , G02B2027/0156
摘要： A collimated head up display of pitch related information for an aircraft operator. A generated pitch signal combines a gyroscope signal referenced to the airframe with an inertial signal referenced to the head up display or combiner screen. A pitch error signal representing the difference between the generated pitch signal and the inertial pitch signal is limited and integrated to develop a pitch correction signal which is added to the gyroscope signal. Reference of the inertial signal to the combiner screen of the display eliminates static alignment errors. The pitch correction signal may be selected for display during alignment of the combiner screen.
摘要翻译：航空器操作员的俯仰相关信息的准直展示。产生的音调信号将参考机身的陀螺仪信号与参考头部显示或组合屏幕的惯性信号相结合。代表产生的音调信号和惯性音调信号之间的差的音调误差信号被限制并积分，以产生加到陀螺仪信号的音调校正信号。将惯性信号引用到显示器的组合屏幕可以消除静态对准误差。可以选择音调校正信号以在组合器屏幕的对准期间显示。

8. 发明授权

US6011040A Use of tetrahydrofolates in natural stereoisomeric form for the production of a pharmaceutical preparation suitable for influencing the homocysteine level, particularly for assisting the remethylation of homocysteine 失效
标题翻译：使用天然立体异构体形式的四氢叶酸盐可用于制备适于影响同型半胱氨酸水平的药物制剂，特别是用于辅助同型半胱氨酸的再甲基化
公开(公告)号：US6011040A
公开(公告)日：2000-01-04
申请号：US95572
申请日：1998-06-11
申请人： Hans Rudolf Muller , Martin Ulmann , Rudolf Moser
发明人： Hans Rudolf Muller , Martin Ulmann , Rudolf Moser
IPC分类号： C07D475/04 , A61K31/4415 , A61K31/505 , A61K31/519 , A61K31/555 , A61P7/00 , A61P9/00 , A61P43/00
CPC分类号： A61K31/519
摘要： This invention relates to the use of tetrahydrofolates in natural stereoisomeric form for the production of a pharmaceutical preparation suitable for influencing the homocysteine level, particularly for assisting the remethylation of homocysteine. Clinical areas of application include all anomalies of the homocysteine level, particularly the prevention and treatment of cardiovascular diseases and the prevention of neural tube deficiencies. The present invention also relates to pharmaceutical preparations comprising at least one compound selected from the group consisting of 5-formyl-(6S)-tetrahydrofolic acid, 5-methyl-(6S)-tetrahydrofolic acid, 5,10-methylene-(6R)-tetrahydrofolic acid, 5,10-methenyl-(6R)-tetrahydrofolic acid, 10-formyl-(6R)-tetrahydrofolic acid, 5-formimino-(6S)-tetra-hydrofolic acid or (6S)-tetrahydrofolic acid or pharmaceutically compatible salts thereof, together with pharmaceutically compatible active and adjuvant substances, for influencing the homocysteine level, particularly when a methylene tetrahydrofolate reductase deficiency exists, such as when thermolabile methylene tetrahydrofolate reductase exists for example.
摘要翻译：本发明涉及以天然立体异构形式的四氢叶酸在制备适于影响同型半胱氨酸水平的药物制剂中的用途，特别是用于辅助同型半胱氨酸的再次乙基化。临床应用领域包括同型半胱氨酸水平的所有异常，特别是预防和治疗心血管疾病和预防神经管缺陷。本发明还涉及包含至少一种选自5-甲酰基 - （6S） - 四氢叶酸，5-甲基 - （6S） - 四氢叶酸，5,10-亚甲基 - （6R） - 四氢叶酸，（6R） - 四氢叶酸，5-甲酰基 - （6R） - 四氢叶酸，5-甲酰基 - （6S） - 四氢叶酸或（6S） - 四氢叶酸或药学上相容的其盐与药学上相容的活性和佐剂物质一起用于影响同型半胱氨酸水平，特别是当存在亚甲基四氢叶酸还原酶缺陷时，例如当存在不可耐受的亚甲基四氢叶酸还原酶时。

9. 发明授权

US3944968A Aircraft ground proximity warning system having speed versus altitude compensation 失效
标题翻译：具有速度与高度补偿的飞机地面接近警戒系统
公开(公告)号：US3944968A
公开(公告)日：1976-03-16
申请号：US520138
申请日：1974-11-01
申请人： Charles D. Bateman , Hans Rudolf Muller
发明人： Charles D. Bateman , Hans Rudolf Muller
IPC分类号： B64D45/04 , G01C5/00 , G01C21/00 , G01C21/20 , G05D1/06
CPC分类号： G05D1/0607 , G01C5/005
摘要： The warning system includes a function generator for generating a signal representative of a minimum altitude over terrain as a function of the aircraft's speed. This signal is combined with a signal representing the aircraft's actual altitude over the terrain and if the aircraft is below this minimum altitude a warning signal is generated. A circuit is included to inhibit the warning signal, and thereby nuisance warnings, when the aircraft overflys another aircraft. In addition, electronic circuitry is disclosed for implementing the invention that is compatible with at least two separate types of air data computers.
摘要翻译：该警报系统包括功能发生器，用于根据飞行器的速度产生代表地形上的最小高度的信号。该信号与表示飞机在地形上的实际高度的信号组合，如果飞机低于该最小高度，则产生警告信号。当航空器飞越另一架飞机时，包括一个电路来抑制警告信号，从而产生滋扰警告。此外，公开了用于实现与至少两种分开类型的空中数据计算机兼容的本发明的电子电路。

10. 发明授权

US07816525B1 Process for the preparation of optically pure tetrahydropterins and derivatives, and specifically of optically pure tetrahydrofolic acid and derivatives thereof, by stereospecific hydrogenation 有权
标题翻译：通过立体特异性氢化制备光学纯四氢叶酸和衍生物，特别是光学纯的四氢叶酸及其衍生物的方法
公开(公告)号：US07816525B1
公开(公告)日：2010-10-19
申请号：US10030692
申请日：2000-07-12
申请人： Hans Rudolf Muller , Rudolf Moser , Viola Groehn , Benoit Pugin
发明人： Hans Rudolf Muller , Rudolf Moser , Viola Groehn , Benoit Pugin
IPC分类号： C07D475/04
CPC分类号： C07D475/04
摘要： Process for the preparation of tetrahydropterin and tetrahydropterin derivatives by hydrogenating pterin and pterin derivatives with hydrogen in the presence of a hydrogenating catalyst, in which the hydrogenation is carried out in a polar reaction medium and metal complexes that are soluble in the reaction medium are employed as the hydrogenation catalysts. The process is suited to the hydrogenation, particularly asymmetric hydrogenation, of folic acid, folic acid salts, folic acid esters, folic acid ester salts or dihydroforms thereof, with the proviso that in the event of using folic acid, carboxylic acid salts thereof or dihydroforms thereof the reaction medium is aqueous, and in the event of using folic acid esters, folic acid ester salts or dihydroforms thereof the reaction medium is an alcohol. The process opens up straightforward access to achiral and chiral pterin derivatives.
摘要翻译：通过在氢化催化剂存在下氢气化蝶呤和蝶呤衍生物，其中氢极化在极性反应介质中进行，可溶于反应介质的金属配合物用作四氢去甲蝶呤和四氢蝶呤衍生物的方法，氢化催化剂。该方法适用于叶酸，叶酸盐，叶酸酯，叶酸酯盐或其二氢形式的氢化，特别是不对称氢化，条件是在使用叶酸的情况下，其羧酸盐或二氢形式其反应介质是水性的，并且在使用叶酸酯，叶酸酯盐或其二氢形式的情况下，反应介质是醇。该方法可以直接获得手性和手性蝶呤衍生物。

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