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    • 5. 发明授权
    • Aryl (ethanoic) propanoic acid ascorbyl ester, preparation method thereof and medicament containing the same
    • (乙酸)丙酸抗坏血酸酯,其制备方法和含有它的药物
    • US08703975B2
    • 2014-04-22
    • US13320101
    • 2009-12-24
    • Luhong TangAjuan DaiZe WangYang SunXinning LiuLingyan XuXin FangShuang QiuYaqing CaoXiaomin XuRuixia JiangChao Wu
    • Luhong TangAjuan DaiZe WangYang SunXinning LiuLingyan XuXin FangShuang QiuYaqing CaoXiaomin XuRuixia JiangChao Wu
    • C07D307/62
    • C07D307/62C07D405/12C07D491/04C07D491/052C12P17/04C12P17/16C12P17/188C12Y301/01003
    • The present invention designs and synthesizes the ascorbyl ester derivatives of the aryl (ethanoic) propanoic acid non-steroidal anti-inflammatory medicaments, such as ibuprofen, ketoprofen and naproxen, and addition salt of the derivatives with pharmaceutical acid or pharmaceutical alkaline. The non-steroidal anti-inflammatory medicament which takes the ibuprofen as the representative is a common antipyretic analgesic medicament. The invention has remarkable antipyretic and analgesic effects and good safety except for anti-inflammatory effect, thus being not only suitable for adults, but also suitable for the elderly people, infants and children. The aryl (ethanoic) propanoic acid ascorbyl ester can be converted into ascorbyl ester derivatives and the addition salts of the derivatives with pharmaceutical acid or pharmaceutical alkaline, which can improve the water solubility thereof, facilitate intravenously administration, reduce the onset time, improve the bioavailability, reduce the stimulation effect to gastrointestinal tract, and enhance the penetrating capacity to hemato encephalic barrier, and can be used as a novel medicament to be applied for antiphlogistic, antipyresis, analgesia, treatment of arthritis, dysmenorrheal, multiple sclerosis, pneumonia cystic fibrosis and patent ductus arteriosus of premature infants, and prevention and treatment of cerebral apoplexy, hypoxic-ischemic brain damage, senile dementia and certain cancers.
    • 本发明设计和合成芳基(乙酸)丙酸非甾体抗炎药物如布洛芬,酮洛芬和萘普生的抗坏血酸酯衍生物,以及衍生物与药物酸或药物碱的加成盐。 以布洛芬为代表的非甾体抗炎药是常见的解热止痛药。 本发明除抗炎作用外,具有明显的解热镇痛作用,安全性好,不仅适用于成人,而且适用于老年人,婴儿和儿童。 芳基(乙酸)丙酸抗坏血酸酯可以转化为抗坏血酸酯衍生物,并且衍生物的加成盐与药物酸或药物碱性可以改善其水溶性,有助于静脉内施用,减少发病时间,提高生物利用度 降低对胃肠道的刺激作用,增强血液渗透屏障的穿透能力,可用作新型药物,用于消炎止痛,止痛,止痛,治疗关节炎,痛经,多发性硬化,肺炎囊性纤维化,以及 早产儿动脉导管未闭,预防和治疗脑中风,缺氧缺血性脑损伤,老年性痴呆和某些癌症。
    • 8. 发明申请
    • Optical engine and an image projector having the optical engine
    • 光学引擎和具有光学引擎的图像投影仪
    • US20060078266A1
    • 2006-04-13
    • US11188183
    • 2005-07-22
    • Chao WuYuan WangJui Pan
    • Chao WuYuan WangJui Pan
    • G02B6/10
    • G02B27/0927G02B27/0994H04N9/315
    • An optical engine for an image projector comprises a light source, a taper rod, at least one light condenser, a prism module, a Digital Micromirror Device (DMD) and a projection lens set. One end of the taper rod is adjacent to the light source. Light generated by the light source is guided by the taper rod following a light path. The taper rod has increasing sizes of cross-sections along the light path, so as to decrease the dispersion angle of light, make the light more uniform, and increase the brightness of light. The prism module includes a first prism having a right triangle cross-section and a second prism having a wedge cross-section. The prism module receives the light from the condenser, passes the light toward the DMD, receives the light reflected by the DMD, and then passes the reflected light toward the projection lens set. The projection lens set projects the light on an external projection plane.
    • 用于图像投影仪的光学引擎包括光源,锥形杆,至少一个光聚光器,棱镜模块,数字微镜器件(DMD)和投影透镜组。 锥形杆的一端与光源相邻。 由光源产生的光由沿着光路的锥形杆引导。 锥形杆具有沿着光路的横截面增大的尺寸,以减小光的色散角,使光线更均匀,并增加光的亮度。 棱镜模块包括具有直角三角形横截面的第一棱镜和具有楔形横截面的第二棱镜。 棱镜模块接收来自聚光器的光,将光朝向DMD传递,接收由DMD反射的光,然后使反射光朝向投影透镜组。 投影透镜组将光投射到外部投影平面上。
    • 9. 发明申请
    • Image projector having a LED light source
    • 具有LED光源的图像投影仪
    • US20060077353A1
    • 2006-04-13
    • US11187481
    • 2005-07-22
    • Chao Wu
    • Chao Wu
    • G03B21/16
    • H04N9/3144G03B21/12G03B21/16
    • An image projector having a LED light source comprises: an optical engine using the LED as the light source, a PCB module, a heat sink module and a main frame. The printed circuit board (PCB) module further comprises: a first circuit board, a second circuit board, at least one I/O interface for connecting an external device, at least one card reader for connecting an external memory card, and a control unit for processing the image data received from the I/O interface or card reader and projecting the image by using the optical engine. The first circuit board and second circuit board are furnished in an overlap and parallel manner to decrease the space consumption. The heat sink module comprises a fan, an air inlet and an air outlet, which substantially forms a heat dissipating passage from the air inlet through the fan toward the air outlet. The LED and control unit are located in the heat dissipating passage for increasing better heat dissipation effect.
    • 具有LED光源的图像投影仪包括:使用LED作为光源的光学引擎,PCB模块,散热模块和主框架。 印刷电路板(PCB)模块还包括:第一电路板,第二电路板,用于连接外部设备的至少一个I / O接口,用于连接外部存储卡的至少一个读卡器和控制单元 用于处理从I / O接口或读卡器接收的图像数据,并通过使用光学引擎投影图像。 第一电路板和第二电路板以重叠和平行的方式设置以减少空间消耗。 散热器模块包括风扇,空气入口和空气出口,其基本形成从空气入口通过风扇朝向空气出口的散热通道。 LED和控制单元位于散热通道中,以提高散热效果。