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1. 发明授权

US6066243A Portable immediate response medical analyzer having multiple testing modules 失效
标题翻译：便携式立即响应医疗分析仪，具有多个测试模块
公开(公告)号：US6066243A
公开(公告)日：2000-05-23
申请号：US119983
申请日：1998-07-21
申请人： Carter R. Anderson , David T. Giddings , James D. Kurkowski , Robbi T. Thompson , Kee Van Sin
发明人： Carter R. Anderson , David T. Giddings , James D. Kurkowski , Robbi T. Thompson , Kee Van Sin
IPC分类号： G01N33/49 , A61B5/145 , A61B5/1455 , A61B5/1468 , G01N27/416 , G01N33/483 , G01N33/487 , G01N33/72 , G01N33/86 , G01N27/26
CPC分类号： G01N33/48785
摘要： A portable device that includes a plurality of test modules for analyzing preselected concentrations of various body fluids of a patient. The portable diagnostic device interfaces and utilizes disposable cartridges and reagent diagnostic test strips and other fluid sample diagnostic devices to determine the amounts of preselected parameters in a patient's blood through either electrochemical, electrical, optical, or mechanical analysis. The disposable fluid sample diagnostic devices may include sample chambers with inlet ports, electrical, physical, or chemical sensors, in situ calibration media, a plurality of electrical interface terminals, and temperature control elements. An electrical interface interconnects the various test modules with one or more corresponding integrated circuits which in turn are electrically coupled to a common interactive display, printer, power supply, and communication ports.
摘要翻译：一种便携式装置，其包括用于分析患者的各种体液的预选浓度的多个测试模块。便携式诊断装置接口并利用一次性药筒和试剂诊断试纸以及其它流体样品诊断装置，以通过电化学，电学，光学或机械分析来确定患者血液中预选参数的量。一次性流体样品诊断装置可以包括具有入口端口，电气，物理或化学传感器，原位校准介质，多个电接口端子和温度控制元件的样品室。电接口将各种测试模块与一个或多个相应的集成电路互连，所述集成电路又电耦合到共同的交互式显示器，打印机，电源和通信端口。

2. 再颁专利

USRE41946E1 Portable immediate response medical analyzer having multiple testing modules 有权
标题翻译：便携式立即响应医疗分析仪，具有多个测试模块
公开(公告)号：USRE41946E1
公开(公告)日：2010-11-23
申请号：US10153081
申请日：2002-05-22
申请人： Carter R. Anderson , David T. Giddings , James D. Kurkowski , Robbi T. Thompson , Kee Van Sin
发明人： Carter R. Anderson , David T. Giddings , James D. Kurkowski , Robbi T. Thompson , Kee Van Sin
IPC分类号： G01N27/327
CPC分类号： G01N33/48785
摘要： A portable device that includes a plurality of test modules for analyzing preselected concentrations of various body fluids of a patient. The portable diagnostic device interfaces and utilizes disposable cartridges and reagent diagnostic test strips and other fluid sample diagnostic devices to determine the amounts of preselected parameters in a patient's blood through either electrochemical, electrical, optical, or mechanical analysis. The disposable fluid sample diagnostic devices may include sample chambers with inlet ports, electrical, physical, or chemical sensors, in situ calibration media, a plurality of electrical interface terminals, and temperature control elements. An electrical interface interconnects the various test modules with one or more corresponding integrated circuits which in turn are electrically coupled to a common interactive display, printer, power supply, and communication ports.
摘要翻译：一种便携式装置，其包括用于分析患者的各种体液的预选浓度的多个测试模块。便携式诊断装置接口并利用一次性药筒和试剂诊断试纸以及其它流体样品诊断装置，以通过电化学，电学，光学或机械分析来确定患者血液中预选参数的量。一次性流体样品诊断装置可以包括具有入口端口，电气，物理或化学传感器，原位校准介质，多个电接口端子和温度控制元件的样品室。电接口将各种测试模块与一个或多个相应的集成电路互连，所述集成电路又电耦合到共同的交互式显示器，打印机，电源和通信端口。

3. 发明授权

US5968329A Interchangeable multiple test system for portable analyzer 失效
标题翻译：便携式分析仪可互换多重测试系统
公开(公告)号：US5968329A
公开(公告)日：1999-10-19
申请号：US851970
申请日：1997-05-06
申请人： Carter R. Anderson , Jon J. Crumm , Martin G. Hieb , Kee Van Sin
发明人： Carter R. Anderson , Jon J. Crumm , Martin G. Hieb , Kee Van Sin
IPC分类号： G01N33/487 , G01N33/49 , G01N37/00 , G01N27/26
CPC分类号： G01N33/4925
摘要： A portable clinical system for providing a rapid electrochemical analysis of biological sera of interest at the point-of-care using a portable analyzer unit and a multi-sensor electrochemical plug-in cartridge analyzing system is disclosed which features a plug-in module including a reusable sensor cartridge having an inlet port for receiving a sample, an outlet drain port and array of self-calibrating electrochemical sensors, a plurality of electrical interfaced terminals for interfacing with the portable analyzer unit. An integral flushing system is provided for cleaning and allowing recalibration of the sensor between sample analyses. Connection devices on the analyzer unit and plug-in multi-use test module are provided for removably attaching the module to the analyzer unit. The connection devices are configured to receive a single-use sensor cartridge interchangeably and without modification with said plug-in multi-use test module.
摘要翻译：公开了一种便携式临床系统，其使用便携式分析仪单元和多传感器电化学插入式盒式分析系统在护理点处提供对感兴趣的生物血清的快速电化学分析，其特征在于插件模块包括可重复使用的传感器盒具有用于接收样品的入口端口，出口排出端口和自校准电化学传感器阵列，用于与便携式分析器单元接口的多个电接口端子。提供一体化的冲洗系统，用于清洁和允许样品分析之间的传感器重新校准。提供分析仪单元和插件多用测试模块上的连接装置，用于将模块可拆卸地连接到分析仪单元。连接装置被配置为可以互换地接收一次性使用的传感器盒，而不用所述插件多用测试模块进行修改。

4. 发明授权

US6150174A Method for measurement of whole blood coagulation parameters 失效
标题翻译：全血凝固参数测定方法
公开(公告)号：US6150174A
公开(公告)日：2000-11-21
申请号：US34478
申请日：1998-03-04
申请人： Kee Van Sin , Carter R. Anderson
发明人： Kee Van Sin , Carter R. Anderson
IPC分类号： G01N33/49 , G01N33/86
CPC分类号： G01N33/86 , G01N33/4905
摘要： The present invention provides a method for determining the coagulation propensity of blood wherein a condition in a portion of a blood sample is assessed and related to the onset of coagulation. Apparatus for performing the method is encompassed by the invention.
摘要翻译：本发明提供一种用于测定血液凝固倾向的方法，其中评估血液样品的一部分的状况并与凝血的发生相关。用于执行该方法的装置包括在本发明中。

5. 发明授权

US09272137B2 Transdermal methods and systems for the delivery of anti-migraine compounds 有权
公开(公告)号：US09272137B2
公开(公告)日：2016-03-01
申请号：US13105562
申请日：2011-05-11
申请人： Carter R. Anderson , Russell L. Morris , Terri B. Sebree
发明人： Carter R. Anderson , Russell L. Morris , Terri B. Sebree
IPC分类号： A61N1/30
CPC分类号： A61K9/7038 , A61K31/4045 , A61N1/30
摘要： Iontophoretic patches for the delivery of anti-migraine compounds and methods of using the patches are described.

6. 发明授权

US08475837B2 Abuse potential reduction in abusable substance dosage form 有权
公开(公告)号：US08475837B2
公开(公告)日：2013-07-02
申请号：US12952516
申请日：2010-11-23
申请人： Carter R. Anderson , Russell L. Morris
发明人： Carter R. Anderson , Russell L. Morris
IPC分类号： A61K9/70
CPC分类号： A62D3/33 , A61J1/00 , A61J1/14 , A61K9/7084 , A61K31/445 , A62D3/00 , A62D2101/26 , B09B3/0075 , B09B2220/14 , B65D25/14
摘要： The potential for substance abuse involving residual amounts of abusable substances remaining in used skin-worn patches is reduced by the provision of a system and method for combining the abusable substance with a separate anti-abuse substance agent as part of a removal or disposal procedure.

7. 发明授权

US08239018B2 Dosage control electrode for iontophoresis device 有权
标题翻译：离子电渗装置用量控制电极
公开(公告)号：US08239018B2
公开(公告)日：2012-08-07
申请号：US12868123
申请日：2010-08-25
申请人： Carter R. Anderson , Russell L. Morris
发明人： Carter R. Anderson , Russell L. Morris
IPC分类号： A61N1/30
CPC分类号： A61N1/0436 , A61N1/044
摘要： An electrode assembly for use in an iontophoresis device for the transcutaneous administration of an active therapeutic species has a base layer of including a linking conductive base material which is consumed (oxidizes or reduces) preferentially to water, a first upper layer of sacrificial material coated on a first portion of the base layer wherein the sacrificial material is consumed preferentially to the linking conductive base material of the base layer. A second upper layer of non-conducting material is coated on a second portion of the base layer, the second upper layer being spaced from the first upper layer, connected by a narrow exposed linking area of the base layer material remaining exposed therebetween. During operation of an associated iontophoresis device, the sacrificial material will be sequentially consumed; the first upper layer will be fully consumed followed by the linking conductive base material of the exposed linking area of the base layer which severs the base layer thereby breaking circuit continuity disabling activity in the device. A visual indicator may be provided allowing a wearer to monitor the state of reaction of the linking area.
摘要翻译：用于经皮给药活性治疗物种的离子电渗疗法装置的电极组件具有包含优先吸收（氧化或还原）水的连接导电基材的基层，涂覆在第一上层的牺牲材料基底层的第一部分，其中牺牲材料优先地消耗到基底层的连接导电基底材料。第二上层非导电材料被涂覆在基层的第二部分上，第二上层与第一上层隔开，第二上层由保留在其间的基层材料的窄暴露的连接区连接。在相关联的离子电渗装置的操作期间，牺牲材料将被顺序消耗; 第一上层将被完全消耗，之后是基底层的暴露的连接区域的连接导电基底材料，其切断基底层，从而破坏器件中的电路连续性失效活动。可以提供视觉指示器，允许佩戴者监视连接区域的反应状态。

8. 发明申请

US20110245755A1 Sacrificial Electrode Design and Delivery Species Suitable for Prolonged Iontophoresis Application Periods 有权
标题翻译：牺牲电极设计和交付物种适用于延长离子渗透应用期
公开(公告)号：US20110245755A1
公开(公告)日：2011-10-06
申请号：US12597941
申请日：2009-08-31
申请人： Kathleen A. Eischen , Carter R. Anderson , Russell L. Morris
发明人： Kathleen A. Eischen , Carter R. Anderson , Russell L. Morris
IPC分类号： A61N1/30
CPC分类号： A61N1/30
摘要： A wearable iontophoresis device for the prolonged delivery of a positively charged pharmaceutical species from a salt formulation is disclosed that includes a readily oxidizable metal-based sacrificial anode in the form of a generally planar layer having a connecting area that has a width that is sufficient to insure complete consumption of the oxidizable metal wherein the anode is configured to have a minimum operating life of at least 6 hours under skin-safe conditions, and a drug delivery gel pad in electrical contact with said anode for accommodating a gel containing a positively charged pharmaceutical species in salt form formulated for transdermal delivery.
摘要翻译：公开了一种用于从盐制剂中延长递送带正电荷的药物物质的可穿戴离子电渗装置，其包括易于氧化的金属基牺牲阳极，其形式为大致平坦的层，其具有连接区域，该连接区域的宽度足以确保完全消耗可氧化金属，其中阳极被配置为在皮肤安全条件下具有至少6小时的最小使用寿命;以及药物递送凝胶垫，其与所述阳极电接触以容纳含有带正电荷的药物配制用于透皮给药的盐形式的物种。

9. 发明申请

US20090062720A1 Transdermal Methods and Systems for the Delivery of Corticosteroid Compounds 有权
标题翻译：用于皮质类固醇化合物递送的透皮方法和系统
公开(公告)号：US20090062720A1
公开(公告)日：2009-03-05
申请号：US12199051
申请日：2008-08-27
申请人： Carter R. Anderson , Russell L. Morris , Robert Cohen , William V. Fowler
发明人： Carter R. Anderson , Russell L. Morris , Robert Cohen , William V. Fowler
IPC分类号： A61N1/30 , A61K9/70
CPC分类号： A61N1/0448 , A61K9/0009 , A61N1/044
摘要： An integrated iontophoresis skin-worn patch and method for delivering a therapeutically effective amount of a corticosteroid drug compound in a systemically-safe and skin-safe manner for site-specific treatment of inflammation pain is disclosed.
摘要翻译：公开了一种用于以系统安全和皮肤安全的方式递送治疗有效量的皮质类固醇药物化合物的综合离子电渗皮肤磨损贴片和方法，用于炎症疼痛的特异性治疗。

10. 发明授权

US07856263B2 Transdermal systems for the delivery of therapeutic agents including granisetron using iontophoresis 有权
标题翻译：用于使用离子电渗法递送治疗剂（包括格拉司琼）的透皮系统
公开(公告)号：US07856263B2
公开(公告)日：2010-12-21
申请号：US11112196
申请日：2005-04-22
申请人： Carter R. Anderson , Walter L. Sembrowich , Russell L. Morris , Robert Cohen
发明人： Carter R. Anderson , Walter L. Sembrowich , Russell L. Morris , Robert Cohen
IPC分类号： A61N1/30 , A61M31/00 , A61F13/00 , A61K9/70
CPC分类号： A61N1/30 , A61M2037/0007 , A61N1/0428 , A61N1/044
摘要： A disposable skin-worn device for the transdermal delivery at least one dose of charged therapeutic substances, including granisetron, by iontophoresis, the device comprising a donor reservoir containing an amount of a therapeutic substance to be delivered transdermally by iontophoresis, a counter reservoir, a source of electric power connected in a circuit between the donor reservoir and the counter reservoir and a control system for controlling current flow in the circuit to enable at least one dose of the therapeutic substance to be delivered transdermally by iontophoresis and wherein the control system includes a control element selected from the group consisting of a sensor activated by an external signal and a switch.
摘要翻译：一种一次性皮肤佩戴的装置，用于透皮输送至少一个剂量的带电治疗物质，包括格拉司琼，通过离子电渗疗法，该装置包括供体储存器，该供体储存器含有通过离子电渗法透皮递送的治疗物质的量，供电源连接在供体储存器和反向储存器之间的电路中，以及控制系统，用于控制电路中的电流流动，以使得至少一个剂量的治疗物质能够通过离子电渗疗法经皮递送，并且其中控制系统包括从由外部信号激活的传感器和开关组成的组中选择的控制元件。

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