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1. 发明授权

US5972441A Thin-wall polytetrafluoroethylene tube 失效
公开(公告)号：US5972441A
公开(公告)日：1999-10-26
申请号：US804851
申请日：1997-02-24
申请人： Carey V. Campbell , Donald G. M. Goffena , James D. Lewis , David J. Myers
发明人： Carey V. Campbell , Donald G. M. Goffena , James D. Lewis , David J. Myers
IPC分类号： A61B17/34 , A61F2/00 , A61F2/06 , A61L29/04 , A61L29/08 , A61L31/04 , A61L31/10 , B29C53/38 , B29C53/58 , B29C70/20 , B29C70/30 , F16L11/08 , B29D22/00
CPC分类号： A61L31/048 , A61L29/041 , A61L29/085 , A61L31/10 , B29C70/207 , B29C70/30 , F16L11/085 , A61B17/3431 , A61F2/07 , A61F2002/072 , A61F2002/075 , A61F2250/0067 , B29C53/38 , B29C53/58 , B29K2027/18 , B29K2105/04 , B29K2105/0827 , B29L2023/005 , B29L2031/7542 , Y10T428/13 , Y10T428/1328 , Y10T428/1352 , Y10T428/1369 , Y10T428/1379 , Y10T428/139 , Y10T428/1393 , Y10T428/1397 , Y10T428/31504 , Y10T428/31536 , Y10T428/3154 , Y10T428/31544
摘要： A thin-wall PTFE (polytetrafluoroethylene) tube in the form of a tube of porous expanded PTFE film wherein the porous PTFE film has a microstructure containing a multiplicity of fibrils oriented substantially parallel to each other. The tube has a wall thickness of less than about 0.25 mm and is made from at least one first layer and at least one second layer of porous PTFE film, wherein the fibrils of the first and second layers are oriented substantially perpendicular to each other. Preferably the fibrils of the at least one first layer are oriented substantially parallel to the longitudinal axis of the tube and the fibrils of the at least one second layer of porous PTFE film are oriented substantially circumferential to the tube. The first and second layers may be inner and outer layers respectively, or alternatively their relationship may be reversed. Alternatively, either of the first and second film layers may be replaced with alternative reinforcing components such as a braid or at least one reinforcing rib.

2. 发明授权

US6027779A Thin-wall polytetrafluoroethylene tube 失效
标题翻译：薄壁聚四氟乙烯管
公开(公告)号：US6027779A
公开(公告)日：2000-02-22
申请号：US247960
申请日：1994-05-24
申请人： Carey V. Campbell , Donald G. M. Goffena , James D. Lewis , David J. Myers , Clayton M. Sparling
发明人： Carey V. Campbell , Donald G. M. Goffena , James D. Lewis , David J. Myers , Clayton M. Sparling
IPC分类号： F16L9/12 , A61B17/34 , A61F2/00 , A61F2/06 , A61L29/04 , A61L29/08 , A61L31/04 , A61L31/10 , B29C53/38 , B29C53/58 , B29C63/10 , B29C70/20 , B29C70/30 , B29D23/00 , B29D23/18 , B32B1/08 , B32B27/02 , B32B27/12 , F16L11/08 , B29D22/00 , B32B9/04
CPC分类号： F16L11/085 , A61F2/06 , A61L27/16 , A61L27/56 , A61L29/041 , A61L29/085 , A61L31/048 , A61L31/10 , B29C70/207 , B29C70/30 , B29D23/001 , B29D23/18 , B32B1/08 , B32B15/02 , B32B15/08 , B32B27/30 , B32B3/02 , B32B3/10 , B32B5/18 , B32B5/32 , A61B17/3431 , A61F2/07 , A61F2002/072 , A61F2002/075 , A61F2250/0067 , B29C53/38 , B29C53/58 , B29C63/10 , B29K2027/18 , B29K2105/04 , B29K2105/048 , B29K2105/0827 , B29K2105/101 , B29K2305/12 , B29L2009/00 , B29L2023/005 , B29L2023/007 , B29L2023/18 , B29L2031/14 , B29L2031/753 , B29L2031/7542 , Y10T428/1355 , Y10T428/1362 , Y10T428/1393 , Y10T428/3154
摘要： A thin-wall PTFE (polytetrafluoroethylene) tube in the form of a tube of porous expanded PTFE film wherein the porous PTFE film has a microstructure containing a multiplicity of fibrils oriented substantially parallel to each other. The tube has a wall thickness of less than about 0.25 mm and is made from at least one first layer and at least one second layer of porous PTFE film, wherein the fibrils of the first and second layers are oriented substantially perpendicular to each other. Preferably the fibrils of the at least one first layer are oriented substantially parallel to the longitudinal axis of the tube and the fibrils of the at least one second layer of porous PTFE film are oriented substantially circumferential to the tube. The first and second layers may be inner and outer layers respectively, or alternatively their relationship may be reversed. Alternatively, either of the first and second film layers may be replaced with alternative reinforcing components such as a braid or at least one reinforcing rib. The reinforcing rib is preferably in the form of a helically-wrapped metal wire located between the first and second layers.
摘要翻译：一种多孔PTFE多孔膜管形式的薄壁PTFE（聚四氟乙烯）管，其中多孔PTFE膜具有包含多个彼此基本平行取向的原纤维的微结构。管具有小于约0.25mm的壁厚，并且由至少一个第一层和至少一层第二层多孔PTFE膜制成，其中第一层和第二层的原纤维彼此基本垂直。优选地，至少一个第一层的原纤维基本上平行于管的纵向轴线定向，并且至少一个第二多孔PTFE膜的原纤维基本上定向到管的周向。第一层和第二层可以分别是内层和外层，或者它们的关系可以相反。或者，第一和第二膜层中的任一个可以用替代的增强部件例如编织物或至少一个加强肋来代替。加强肋优选为位于第一和第二层之间的螺旋缠绕的金属线的形式。

3. 发明授权

US6025044A Thin-wall polytetrafluoroethylene tube 失效
标题翻译：薄壁聚四氟乙烯管
公开(公告)号：US6025044A
公开(公告)日：2000-02-15
申请号：US204708
申请日：1994-03-02
申请人： Carey V. Campbell , James D. Lewis , David J. Myers
发明人： Carey V. Campbell , James D. Lewis , David J. Myers
IPC分类号： A61B17/34 , A61F2/00 , A61F2/06 , A61L29/04 , A61L29/08 , A61L31/04 , A61L31/10 , B29C53/38 , B29C53/58 , B29C63/10 , B29C70/20 , B29C70/30 , B29D23/00 , B29D23/18 , F16L11/08 , B29D22/00 , B32B9/04 , A61F2/24
CPC分类号： B29D23/18 , A61F2/06 , A61L27/16 , A61L27/56 , A61L29/041 , A61L29/085 , A61L31/048 , A61L31/10 , B29C70/207 , B29C70/30 , B29D23/001 , B32B1/08 , B32B15/02 , B32B15/08 , B32B27/30 , B32B3/02 , B32B3/10 , B32B5/18 , B32B5/32 , F16L11/085 , A61B17/3431 , A61F2/07 , A61F2002/072 , A61F2002/075 , A61F2250/0067 , B29C53/38 , B29C53/58 , B29C63/10 , B29K2027/18 , B29K2105/04 , B29K2105/048 , B29K2105/0827 , B29K2105/101 , B29K2305/12 , B29L2009/00 , B29L2023/005 , B29L2023/007 , B29L2023/18 , B29L2031/14 , B29L2031/753 , B29L2031/7542 , Y10S623/90 , Y10T428/1352 , Y10T428/1355 , Y10T428/1362 , Y10T428/139 , Y10T428/1393 , Y10T428/1397 , Y10T428/31504 , Y10T428/3154 , Y10T428/31544
摘要： A thin-wall PTFE (polytetrafluoroethylene) tube in the form of a tube of porous expanded PTFE film wherein the porous PTFE film has a microstructure containing a multiplicity of fibrils oriented substantially parallel to each other. The tube has a wall thickness of less than about 0.25 mm and is made from at least one first layer and at least one second layer of porous PTFE film, wherein the fibrils of the first and second layers are oriented substantially perpendicular to each other. Preferably the fibrils of the at least one first layer are oriented substantially parallel to the longitudinal axis of the tube and the fibrils of the at least one second layer of porous PTFE film are oriented substantially circumferential to the tube. The first and second layers may be inner and outer layers respectively, or alternatively their relationship may be reversed. Alternatively, either of the first and second film layers may be replaced with alternative reinforcing components such as a braid or at least one reinforcing rib.
摘要翻译：一种多孔PTFE多孔膜管形式的薄壁PTFE（聚四氟乙烯）管，其中多孔PTFE膜具有包含多个彼此基本平行取向的原纤维的微结构。管具有小于约0.25mm的壁厚，并且由至少一个第一层和至少一层第二层多孔PTFE膜制成，其中第一层和第二层的原纤维彼此基本垂直。优选地，至少一个第一层的原纤维基本上平行于管的纵向轴线定向，并且至少一个第二多孔PTFE膜的原纤维基本上定向到管的周向。第一层和第二层可以分别是内层和外层，或者它们的关系可以相反。或者，第一和第二膜层中的任一个可以用替代的增强部件例如编织物或至少一个加强肋来代替。

4. 发明授权

US5800522A Interior liner for tubes, pipes and blood conduits 失效
标题翻译：用于管道，管道和血管的内衬
公开(公告)号：US5800522A
公开(公告)日：1998-09-01
申请号：US789378
申请日：1997-01-24
申请人： Carey V. Campbell , James F. Kasic, II , Larry J. Kovach , Alvaro J. Laguna , James D. Lewis , Mark E. Mayrand , David J. Myers , Stanislaw L. Zukowski
发明人： Carey V. Campbell , James F. Kasic, II , Larry J. Kovach , Alvaro J. Laguna , James D. Lewis , Mark E. Mayrand , David J. Myers , Stanislaw L. Zukowski
IPC分类号： A61B17/12 , A61F2/00 , A61F2/92 , B29C47/00 , B29C53/58 , B29C55/24 , B29C63/34 , F16L11/12 , A61F2/06
CPC分类号： A61F2/92 , A61B17/12022 , A61B17/12109 , A61B17/12118 , A61F2/07 , B29C47/0019 , B29C55/24 , B29C63/34 , F16L11/12 , A61F2/90 , A61F2002/075 , A61F2002/30289 , A61F2210/0076 , A61F2220/0008 , A61F2220/0075 , A61F2230/0091 , B29C47/00 , B29C47/0023 , B29C47/0042 , B29C47/0064 , B29C47/02 , B29C47/065 , B29C53/58 , B29K2027/18 , B29K2105/04 , B29K2995/0072 , B29L2023/007
摘要： A tube which circumferentially distends from its initial circumference upon the application of a circumferentially distending force such as applied by an internal pressure, and which exhibits minimal recoil following the removal of the circumferentially distending force. The tube preferably has a second circumference larger than the initial circumference which remains substantially unchanged by further increasing force once it has been achieved. Because of the distensible circumference and minimal recoil of the tube, the tube is useful as a liner for pipes and vessels and particularly for pipes and vessels having irregular internal surfaces to which the tube can smoothly conform. The tube is preferably made from porous PTFE with thin walls, in which form it is particularly useful as a liner for both living and prosthetic blood vessels and to line anastomoses between living and prosthetic blood vessels. The tube or any other intraluminal graft may be used in in situ bypass procedures to hold venous valves open and to occlude tributary branches. Covered stents may be used for the same purpose; stents without such a covering may also be used to hold venous valves open.
摘要翻译：在施加周向上的膨胀力（例如通过内部压力施加）上周向地从其初始周边延伸的管，并且在除去周向膨胀力之后表现出最小的反冲。该管优选地具有大于初始周长的第二圆周，其一旦达到，则通过进一步增加的力而保持基本上不变。由于管的可伸缩周长和最小的后坐力，管可用作管和容器的衬套，特别是用于具有不规则内表面的管和容器，管可以顺利地对准管。管优选地由具有薄壁的多孔PTFE制成，其中形式特别可用作活体和假体血管的衬垫，并且在活体和假体血管之间排列吻合。管或任何其他管腔内移植物可以用于原位旁路手术以将静脉瓣保持开放并阻塞支流分支。覆盖支架可用于相同的目的; 没有这种覆盖物的支架也可用于保持静脉瓣开放。

5. 发明申请

US20120310326A1 INTERIOR LINER FOR TUBES, PIPES, AND BLOOD CONDUITS 审中-公开
标题翻译：管道，管道和血液导管的内部衬管
公开(公告)号：US20120310326A1
公开(公告)日：2012-12-06
申请号：US13590077
申请日：2012-08-20
申请人： Carey V. Campbell , Alvaro J. Laguna , James D. Lewis , Mark E. Mayrand , David J. Myers
发明人： Carey V. Campbell , Alvaro J. Laguna , James D. Lewis , Mark E. Mayrand , David J. Myers
IPC分类号： A61F2/82 , A61F2/06
CPC分类号： A61F2/92 , A61B17/12022 , A61B17/12109 , A61B17/12118 , A61F2/07 , A61F2/90 , A61F2002/075 , A61F2002/30289 , A61F2210/0076 , A61F2220/0008 , A61F2220/0075 , A61F2230/0091 , B29C48/00 , B29C48/0012 , B29C48/0021 , B29C48/07 , B29C48/09 , B29C48/15 , B29C48/21 , B29C53/58 , B29C55/24 , B29C63/34 , B29K2027/18 , B29K2105/04 , B29K2995/0072 , B29L2023/007 , F16L11/12
摘要： A tube which circumferentially distends from its initial circumference upon the application of a circumferentially distending force such as applied by an internal pressure, and which exhibits minimal recoil following the removal of the circumferentially distending force. The tube preferably has a second circumference larger than the initial circumference which remains substantially unchanged by further increasing force once it has been achieved. Because of the distensible circumference and minimal recoil of the tube, the tube is useful as a liner for pipes and vessels and particularly for pipes and vessels having irregular internal surfaces to which the tube can smoothly conform. The tube is preferably made from porous PTFE with thin walls, in which form it is particularly useful as a liner for both living and prosthetic blood vessels and to line anastomoses between living and prosthetic blood vessels.
摘要翻译：在施加周向上的膨胀力（例如通过内部压力施加）上周向地从其初始周边延伸的管，并且在除去周向膨胀力之后表现出最小的反冲。该管优选地具有大于初始周长的第二圆周，其一旦达到，则通过进一步增加的力而保持基本上不变。由于管的可伸缩周长和最小的后坐力，管可用作管和容器的衬套，特别是用于具有不规则内表面的管和容器，管可以顺利地对准管。管优选地由具有薄壁的多孔PTFE制成，其中形式特别可用作活体和假体血管的衬垫，并且在活体和假体血管之间排列吻合。

6. 发明授权

US6159565A Thin-wall intraluminal graft 失效
标题翻译：薄壁管腔内移植
公开(公告)号：US6159565A
公开(公告)日：2000-12-12
申请号：US108963
申请日：1993-08-18
申请人： Carey V. Campbell , James D. Lewis , David J. Myers
发明人： Carey V. Campbell , James D. Lewis , David J. Myers
IPC分类号： A61B17/34 , A61F2/00 , A61F2/06 , A61L29/04 , A61L29/08 , A61L31/04 , A61L31/10 , B29C53/38 , B29C53/58 , B29C70/20 , B29C70/30 , F16L11/08 , B29D22/00
CPC分类号： A61L31/048 , A61B17/3431 , A61F2/07 , A61F2002/072 , A61F2002/075 , A61F2250/0067 , A61L29/041 , A61L29/085 , A61L31/10 , B29C53/38 , B29C53/58 , B29C70/207 , B29C70/30 , B29K2027/18 , B29K2105/04 , B29K2105/0827 , B29L2023/005 , B29L2031/7542 , F16L11/085 , Y10T428/13 , Y10T428/1328 , Y10T428/1352 , Y10T428/1369 , Y10T428/1379 , Y10T428/139 , Y10T428/1393 , Y10T428/1397 , Y10T428/31504 , Y10T428/31536 , Y10T428/3154 , Y10T428/31544 , C08L27/18
摘要： An intraluminal vascular graft in the form of a tube of porous expanded polytetrafluoroethylene film wherein the porous polytetrafluoroethylene film has a microstructure containing a multiplicity of fibrils oriented substantially parallel to each other. The tube has a wall thickness of less than about 0.25 mm and is made from at least one first layer and at least one second layer of porous polytetrafluoroethylene film, wherein the fibrils of the first and second layers are oriented substantially perpendicular to each other. Preferably the fibrils of the at least one first layer are oriented substantially parallel to the longitudinal axis of the tube and the fibrils of the at least one second layer of porous polytetrafluoroethylene film are oriented substantially circumferential to the tube. The first and second layers may be inner and outer layers respectively, or alternatively their relationship may be reversed. Alternatively, either of the first and second film layers may be replaced with alternative reinforcing components such as a braid or at least one reinforcing rib.
摘要翻译：以多孔膨体聚四氟乙烯膜管形式的管腔内血管移植物，其中多孔聚四氟乙烯膜具有包含相互平行取向的多个原纤维的微结构。该管具有小于约0.25mm的壁厚，并且由至少一个第一层和至少一层第二层多孔聚四氟乙烯膜制成，其中第一层和第二层的原纤维彼此基本垂直。优选地，至少一个第一层的原纤维基本上平行于管的纵向轴线定向，并且至少一个第二层多孔聚四氟乙烯膜的原纤维基本上圆周地取向管。第一层和第二层可以分别是内层和外层，或者它们的关系可以相反。或者，第一和第二膜层中的任一个可以用替代的增强部件例如编织物或至少一个加强肋来代替。

7. 发明授权

US6027811A Thin-wall intraluminal graft 失效
公开(公告)号：US6027811A
公开(公告)日：2000-02-22
申请号：US486124
申请日：1995-06-07
申请人： Carey V. Campbell , James D. Lewis , David J. Myers
发明人： Carey V. Campbell , James D. Lewis , David J. Myers
IPC分类号： A61B17/34 , A61F2/00 , A61F2/06 , A61L29/04 , A61L29/08 , A61L31/04 , A61L31/10 , B29C53/38 , B29C53/58 , B29C70/20 , B29C70/30 , F16L11/08 , B32B9/04
CPC分类号： A61L31/048 , A61L29/041 , A61L29/085 , A61L31/10 , B29C70/207 , B29C70/30 , F16L11/085 , A61B17/3431 , A61F2/07 , A61F2002/072 , A61F2002/075 , A61F2250/0067 , B29C53/38 , B29C53/58 , B29K2027/18 , B29K2105/04 , B29K2105/0827 , B29L2023/005 , B29L2031/7542 , Y10T428/13 , Y10T428/1328 , Y10T428/1352 , Y10T428/1369 , Y10T428/1379 , Y10T428/139 , Y10T428/1393 , Y10T428/1397 , Y10T428/31504 , Y10T428/31536 , Y10T428/3154 , Y10T428/31544
摘要： An intraluminal vascular graft in the form of a tube of porous expanded polytetrafluoroethylene film wherein the porous polytetrafluoroethylene film has a microstructure containing a multiplicity of fibrils oriented substantially parallel to each other. The tube has a wall thickness of less than about 0.25 mm and is made from at least one first layer and at least one second layer of porous polytetrafluoroethylene film, wherein the fibrils of the first and second layers are oriented substantially perpendicular to each other. Preferably the fibrils of the at least one first layer are oriented substantially parallel to the longitudinal axis of the tube and the fibrils of the at least one second layer of porous polytetrafluoroethylene film are oriented substantially circumferential to the tube. The first and second layers may be inner and outer layers respectively, or alternatively their relationship may be reversed. Alternatively, either of the first and second film layers may be replaced with alternative reinforcing components such as a braid or at least one reinforcing rib.

8. 发明授权

US5976650A Method of securing a thin-wall intraluminal graft 失效
标题翻译：确保薄壁管腔内移植物的方法
公开(公告)号：US5976650A
公开(公告)日：1999-11-02
申请号：US486123
申请日：1995-06-07
申请人： Carey V. Campbell , James D. Lewis , David J. Myers
发明人： Carey V. Campbell , James D. Lewis , David J. Myers
IPC分类号： A61B17/34 , A61F2/00 , A61F2/06 , A61L29/04 , A61L29/08 , A61L31/04 , A61L31/10 , B29C53/38 , B29C53/58 , B29C70/20 , B29C70/30 , F16L11/08 , B29D22/00
CPC分类号： A61L31/048 , A61L29/041 , A61L29/085 , A61L31/10 , B29C70/207 , B29C70/30 , F16L11/085 , A61B17/3431 , A61F2/07 , A61F2002/072 , A61F2002/075 , A61F2250/0067 , B29C53/38 , B29C53/58 , B29K2027/18 , B29K2105/04 , B29K2105/0827 , B29L2023/005 , B29L2031/7542 , Y10T428/13 , Y10T428/1328 , Y10T428/1352 , Y10T428/1369 , Y10T428/1379 , Y10T428/139 , Y10T428/1393 , Y10T428/1397 , Y10T428/31504 , Y10T428/31536 , Y10T428/3154 , Y10T428/31544
摘要： A method of securing an intraluminal vascular graft within a living body, the intraluminal vascular graft being in the form of a tube of porous expanded polytetrafluoroethylene film wherein the porous polytetrafluoroethylene film has a microstructure containing a multiplicity of fibrils oriented substantially parallel to each other. The tube has a wall thickness of less than about 0.25 mm and is made from at least one first layer and at least one second layer of porous polytetrafluoroethylene film, wherein the fibrils of the first and second layers are oriented substantially perpendicular to each other. Preferably the fibrils of the at least one first layer are oriented substantially parallel to the longitudinal axis of the tube and the fibrils of the at least one second layer of porous polytetrafluoroethylene film are oriented substantially circumferential to the tube. The first and second layers may be inner and outer layers respectively, or alternatively their relationship may be reversed. Alternatively, either of the first and second film layers may be replaced with alternative reinforcing components such as a braid or at least one reinforcing rib.
摘要翻译：一种将腔内血管移植物固定在活体内的方法，所述管腔内血管移植物呈多孔扩张聚四氟乙烯膜的形式，其中所述多孔聚四氟乙烯膜具有包含基本上彼此平行取向的多个原纤维的微结构。该管具有小于约0.25mm的壁厚，并且由至少一个第一层和至少一层第二层多孔聚四氟乙烯膜制成，其中第一层和第二层的原纤维彼此基本垂直。优选地，至少一个第一层的原纤维基本上平行于管的纵向轴线定向，并且至少一个第二层多孔聚四氟乙烯膜的原纤维基本上圆周地取向管。第一层和第二层可以分别是内层和外层，或者它们的关系可以相反。或者，第一和第二膜层中的任一个可以用替代的增强部件例如编织物或至少一个加强肋来代替。

9. 发明授权

US5700287A Prosthetic vascular graft with deflectably secured fibers 失效
标题翻译：假体血管移植物具有可偏转固定的纤维
公开(公告)号：US5700287A
公开(公告)日：1997-12-23
申请号：US743954
申请日：1996-10-29
申请人： David J. Myers , James D. Lewis , Carey V. Campbell
发明人： David J. Myers , James D. Lewis , Carey V. Campbell
IPC分类号： A61F2/06 , A61L27/50 , A61M39/04 , A61F2/04
CPC分类号： A61M39/04 , A61F2/06 , A61L27/507
摘要： A vascular graft in the form of a tube or flat sheet of biocompatible material having an outer covering of deflectably secured material such as porous film, fibers, discrete pieces of material, or combinations thereof. Two different types of fibers may also be used. The vascular graft may be of tubular form for replacing or bypassing entire segments of veins or arteries or alternatively may be in the form of a flat sheet useful for repairing portions of the circumference of veins or arteries. The tube or flat sheet of biocompatible material and the outer covering of deflectably secured material are preferably of porous polytetrafluoroethylene. The inventive vascular graft is useful for dialysis access in that it offers a reduction in blood leakage when the vascular graft is punctured by a dialysis needle and the needle is subsequently removed. It is also useful for reducing suture hole bleeding resulting from holes created through the graft by penetration of the graft with a suture needle.
摘要翻译：具有生物相容性材料的管或平片形式的血管移植物，其具有可偏转地固定的材料的外覆盖物，例如多孔膜，纤维，分立的材料片或其组合。也可以使用两种不同类型的纤维。血管移植物可以是用于替代或绕过静脉或动脉的整个部分的管状形式，或者可以是用于修复静脉或动脉周围部分的平板形式。生物相容性材料的管或平板和可偏转固定的材料的外覆层优选为多孔聚四氟乙烯。本发明的血管移植物可用于透析进入，因为当血管移植物被透析针刺穿并且随后除去针时，其提供血液渗漏的减少。它也可用于通过用缝合针穿透移植物来减少由通过移植物产生的孔产生的缝线孔渗出。

10. 发明授权

US5628782A Method of making a prosthetic vascular graft 失效
标题翻译：制造假体血管移植物的方法
公开(公告)号：US5628782A
公开(公告)日：1997-05-13
申请号：US88599
申请日：1993-08-17
申请人： David J. Myers , James D. Lewis , Carey V. Campbell
发明人： David J. Myers , James D. Lewis , Carey V. Campbell
IPC分类号： A61F2/06 , A61L27/50 , A61M39/04 , A61F2/04
CPC分类号： A61M39/04 , A61F2/06 , A61L27/507
摘要： A vascular graft in the form of a tube or flat sheet of biocompatible material having an outer covering of deflectably secured material such as porous film, fibers, discrete pieces of material, or combinations thereof. Two different types of fibers may also be used. The vascular graft may be of tubular form for replacing or bypassing entire segments of veins or arteries or alternatively may be in the form of a flat sheet useful for repairing portions of the circumference of veins or arteries. The tube or flat sheet of biocompatible material and the outer covering of deflectably secured material are preferably of porous polytetrafluoroethylene. The inventive vascular graft is useful for dialysis access in that it offers a reduction in blood leakage when the vascular graft is punctured by a dialysis needle and the needle is subsequently removed. It is also useful for reducing suture hole bleeding resulting from holes created through the graft by penetration of the graft with a suture needle.
摘要翻译：具有生物相容性材料的管或平片形式的血管移植物，其具有可偏转地固定的材料的外覆盖物，例如多孔膜，纤维，分立的材料片或其组合。也可以使用两种不同类型的纤维。血管移植物可以是用于替代或绕过静脉或动脉的整个部分的管状形式，或者可以是用于修复静脉或动脉周围部分的平板形式。生物相容性材料的管或平板和可偏转固定的材料的外覆层优选为多孔聚四氟乙烯。本发明的血管移植物可用于透析进入，因为当血管移植物被透析针刺穿并且随后除去针时，其提供血液渗漏的减少。它也可用于通过用缝合针穿透移植物来减少由通过移植物产生的孔产生的缝线孔渗出。

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