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    • 4. 发明申请
    • Alignment of multicomponent microfabricated structures
    • 多组分微制造结构的对齐
    • US20060261033A1
    • 2006-11-23
    • US11497464
    • 2006-07-31
    • Jeffrey WolkRichard McReynoldsJ. Parce
    • Jeffrey WolkRichard McReynoldsJ. Parce
    • C23F1/00
    • B01L3/502707B01L2300/0816B01L2300/0887B01L2400/0415B01L2400/0487
    • Multilayered microfluidic devices include structures that are used to align elements that make up the devices. Such elements include additional substrate layers, external sampling elements, and the like. In one embodiment, a multilayered microfluidic device includes first and second substrate layers attached one to the other, each substrate layer having a notch in an edge of the substrate layer. The notches are positioned such that they circumscribe a single opening into which an alignment key is inserted. In a method of fabricating a multilayered microfluidic device, notches are provided in first and second substrate layers, the notches circumscribing a single opening when the substrate layers are mated together. An alignment key is inserted into the single opening, and the substrate layers are bonded together. The alignment key may be, for example, a shim or a capillary element.
    • 多层微流体装置包括用于对准构成装置的元件的结构。 这些元件包括附加的基底层,外部取样元件等。 在一个实施例中,多层微流体装置包括彼此附接的第一和第二衬底层,每个衬底层在衬底层的边缘中具有凹口。 凹口定位成使得它们围绕插入对准键的单个开口。 在制造多层微流体装置的方法中,在第一和第二衬底层中设置缺口,当衬底层配合在一起时,限制单个开口的凹口。 将对准键插入到单个开口中,并且将基底层粘结在一起。 对准键可以是例如垫片或毛细管元件。