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1. 发明授权

US06701425B1 Memory access address comparison of load and store queques 有权
标题翻译：存储访问地址比较负载和存储量
公开(公告)号：US06701425B1
公开(公告)日：2004-03-02
申请号：US09563153
申请日：2000-05-02
申请人： Ahmed Dabbagh , Nicolas Grossier , Bruno Bernard , Pierre-Yves Taloud
发明人： Ahmed Dabbagh , Nicolas Grossier , Bruno Bernard , Pierre-Yves Taloud
IPC分类号： G06F930
CPC分类号： G06F9/3834
摘要： A computer system with parallel execution pipelines and a memory access controller has store address queues holding addresses for store operations, store data queues holding a plurality of data for storing in the memory and load address storage holding addresses for load operations, said access controller including comparator circuitry to compare load addresses received by the controller with addresses in the store address queue and locate any addresses which are the same, each of said addresses including a first set of bits representing a word address together with a second set of byte enable bits and said comparator having circuitry to compare the byte enable bits of two addresses as well as said first set of bits.
摘要翻译：具有并行执行管线和存储器访问控制器的计算机系统具有保存用于存储操作的地址的存储地址队列，保存用于存储在存储器中的多个数据的存储数据队列和用于加载操作的加载地址存储保持地址，所述访问控制器包括比较器用于将由控制器接收的负载地址与存储地址队列中的地址进行比较并且定位任何相同的地址的电路，每个所述地址包括表示字地址的第一组位与第二组字节使能位和所述比较器具有用于比较两个地址的字节使能位以及所述第一组位的电路。

2. 发明授权

US06769049B1 Memory access in a computer system having parallel execution pipelines 有权
标题翻译：具有并行执行管线的计算机系统中的存储器访问
公开(公告)号：US06769049B1
公开(公告)日：2004-07-27
申请号：US09563473
申请日：2000-05-02
申请人： Bruno Bernard , Nicolas Grossier , Ahmed Dabbagh
发明人： Bruno Bernard , Nicolas Grossier , Ahmed Dabbagh
IPC分类号： G06F1300
CPC分类号： G06F13/1631 , G06F9/30072 , G06F9/3834
摘要： A computer memory access controller receives load and store requests from a plurality of parallel execution pipelines and forms queues of store and load addresses. A comparator compares load addresses with store addresses in a store address queue and selects a store before load if an address match is found, but selects a load before a store if no address match is found.
摘要翻译：计算机存储器访问控制器从多个并行执行流水线接收加载和存储请求并形成存储和加载地址的队列。比较器将加载地址与存储地址队列中的存储地址进行比较，如果找到地址匹配，则在加载之前选择存储，但如果找不到地址匹配，则在存储之前选择一个负载。

3. 发明申请

US20100105741A1 ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS 审中-公开
标题翻译：吡啶二羧酸化合物的施用用于刺激或诱导人类激素纤维的生长和/或损害它们的损失
公开(公告)号：US20100105741A1
公开(公告)日：2010-04-29
申请号：US12650777
申请日：2009-12-31
申请人： Maria Dalko , Geneviève Loussouarn , Charles El Rawadi , Christophe Boulle , Bruno Bernard
发明人： Maria Dalko , Geneviève Loussouarn , Charles El Rawadi , Christophe Boulle , Bruno Bernard
IPC分类号： A61K31/44
CPC分类号： A61K8/4926 , A61K8/37 , A61K8/494 , A61K8/4953 , A61Q1/10 , A61Q7/00
摘要： The invention relates to the use in a composition for caring for human hair or eyelashes of an effective amount of a pyridinedicarboxylic acid derivative of general formula (I) or of one of its salts, in which R1 and R2 represent, independently of one another, OH, OR′, —NH2, —NHR′ or —NR′R″, and R′ and R″ represent, independently of one another, a saturated or unsaturated and linear or branched C1-C18 alkyl radical or an aryl radical, this alkyl or aryl radical optionally being substituted by at least one OH, alkoxy, acyloxy, amino or alkylamino group, or R′ and R″ together represent a heterocycle, the composition being intended to induce and/or stimulate the growth of human keratinous fibers, such as the hair and eyelashes, and/or slow down their loss; the invention also relates to a cosmetic treatment intended to stimulate the growth of human keratinous fibers, such as the hair and eyelashes, and/or slow down their loss.
摘要翻译：本发明涉及用于照护人发或睫毛的组合物中有效量的通式（I）的吡啶二羧酸衍生物或其盐之一，其中R 1和R 2彼此独立地表示， OH，OR'，-NH 2，-NHR'或-NR'R“，R'和R”彼此独立地表示饱和或不饱和和直链或支链的C 1 -C 18烷基或芳基，任选被至少一个OH，烷氧基，酰氧基，氨基或烷基氨基取代的烷基或芳基，或R'和R“一起表示杂环，该组合物旨在诱导和/或刺激人角质纤维的生长，如头发和睫毛，和/或减慢他们的损失; 本发明还涉及旨在刺激人角质纤维如头发和睫毛的生长和/或减缓其损失的美容治疗。

4. 发明授权

US07585514B2 Administration of agents mimicking DOPAchrome tautomerase (TRP-2) activity for protecting hair follicle melanocytes 有权
标题翻译：给予模仿DOPAchrome互变异构酶（TRP-2）活性以保护毛囊黑素细胞的药剂
公开(公告)号：US07585514B2
公开(公告)日：2009-09-08
申请号：US11009153
申请日：2004-12-13
申请人： Stephane Commo , Olivier Gaillard , Bruno Bernard
发明人： Stephane Commo , Olivier Gaillard , Bruno Bernard
IPC分类号： A61K8/02
CPC分类号： C12Q1/533 , A61K8/19 , A61Q5/00 , A61Q5/02 , A61Q5/06 , A61Q5/10
摘要： Agents mimicking DOPAchrome tautomerase activity are administered, notably topically applied, to protect and/or regenerate the melanocytes of hair follicles, to promote the cyclic renewal of the follicular pigmentation unit, to prevent and/or limit and/or arrest the development of canities, and to maintain the natural pigmentation of gray or white head hair and/or body hair.
摘要翻译：施用模仿DOPAchrome互变异构酶活性的试剂，特别是局部应用，以保护和/或再生毛囊的黑素细胞，促进滤泡色素沉着单位的循环更新，以预防和/或限制和/或阻止囊泡的发育，并保持灰色或白色头发和/或身体毛发的天然色素沉着。

5. 发明申请

US20070123471A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process 有权
标题翻译：葡萄糖和维生素F的衍生物，包含其的组合物，用途和制备方法
公开(公告)号：US20070123471A1
公开(公告)日：2007-05-31
申请号：US11657532
申请日：2007-01-25
申请人： Jean-Francois Michelet , Maria Dalko , Bruno Bernard , Didier Semeria , Michel Philippe
发明人： Jean-Francois Michelet , Maria Dalko , Bruno Bernard , Didier Semeria , Michel Philippe
IPC分类号： A61K31/7024 , A61K8/73 , C07H13/02
CPC分类号： C07H13/06 , A61K8/34 , A61K8/602 , A61K8/731 , A61K31/133 , A61K31/192 , A61K31/4412 , A61K31/7024 , A61K31/717 , A61Q5/006 , A61Q5/02 , A61Q7/00 , C07H1/00 , C07H13/02 , Y10S514/88
摘要： An O-acyl product derived from glucose which may be obtained by partial or total esterification of glucose and of vitamin F, comprising a mixture of esters, for example, monoesters, of glucose and of at least one acid chosen from linoleic acid, oleic acid, palmitic acid and stearic acid, compositions, for example, cosmetic and pharmaceutical compositions, comprising this novel derivative, and their use for improving the condition of head hair and/or other hairs, and, for example, for reducing and/or impeding the loss of head hair and/or other hairs, and/or for inducing and/or stimulating hair growth, as well as a process for preparing O-acyl derivatives mainly in position 6 of glucose, comprising preparing a mixed anhydride by reacting a carboxylic acid with a trimethylacetyl halide, followed by reacting said mixed anhydride formed with glucose.
摘要翻译：衍生自葡萄糖的O-酰基产物可以通过葡萄糖和维生素F的部分或全部酯化获得，其包含葡萄糖和至少一种选自亚油酸，油酸的酸的酯，例如单酯的混合物，棕榈酸和硬脂酸，组合物，例如包含该新型衍生物的化妆品和药物组合物，以及它们用于改善头发和/或其它毛发的状况的用途，并且例如用于减少和/或阻碍头发和/或其他毛发的丧失和/或用于诱导和/或刺激毛发生长的方法，以及主要在葡萄糖6位上制备O-酰基衍生物的方法，包括通过使羧酸与三甲基乙酰卤反应，然后与形成的葡萄糖形成的混合酸酐反应。

6. 发明申请

US20060166902A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process 有权
标题翻译：葡萄糖和维生素F的衍生物，包含其的组合物，用途和制备方法
公开(公告)号：US20060166902A1
公开(公告)日：2006-07-27
申请号：US11393829
申请日：2006-03-31
申请人： Jean-Francois Michelet , Maria Dalko , Bruno Bernard , Didier Semeria , Michel Philippe
发明人： Jean-Francois Michelet , Maria Dalko , Bruno Bernard , Didier Semeria , Michel Philippe
IPC分类号： A61K31/7024 , C07F3/10
CPC分类号： C07H13/06 , A61K8/34 , A61K8/602 , A61K8/731 , A61K31/133 , A61K31/192 , A61K31/4412 , A61K31/7024 , A61K31/717 , A61Q5/006 , A61Q5/02 , A61Q7/00 , C07H1/00 , C07H13/02 , Y10S514/88
摘要： An O-acyl product derived from glucose which may be obtained by partial or total esterification of glucose and of vitamin F, comprising a mixture of esters, for example, monoesters, of glucose and of at least one acid chosen from linoleic acid, oleic acid, palmitic acid and stearic acid, compositions, for example, cosmetic and pharmaceutical compositions, comprising this novel derivative, and their use for improving the condition of head hair and/or other hairs, and, for example, for reducing and/or impeding the loss of head hair and/or other hairs, and/or for inducing and/or stimulating hair growth, as well as a process for preparing O-acyl derivatives mainly in position 6 of glucose, comprising preparing a mixed anhydride by reacting a carboxylic acid with a trimethylacetyl halide, followed by reacting said mixed anhydride formed with glucose.
摘要翻译：衍生自葡萄糖的O-酰基产物可以通过葡萄糖和维生素F的部分或全部酯化获得，其包含葡萄糖和至少一种选自亚油酸，油酸的酸的酯，例如单酯的混合物，棕榈酸和硬脂酸，组合物，例如包含该新型衍生物的化妆品和药物组合物，以及它们用于改善头发和/或其它毛发的状况的用途，并且例如用于减少和/或阻碍头发和/或其他毛发的丧失和/或用于诱导和/或刺激毛发生长的方法，以及主要在葡萄糖6位上制备O-酰基衍生物的方法，包括通过使羧酸与三甲基乙酰卤反应，然后与形成的葡萄糖形成的混合酸酐反应。

7. 发明申请

US20050208086A1 Administration of agents inducing DOPAchrome tautomerase (TRP-2) expression for protecting hair follicle melanocytes 审中-公开
标题翻译：诱导诱导DOPAchrome互变异构酶（TRP-2）表达以保护毛囊黑素细胞的药剂的给药
公开(公告)号：US20050208086A1
公开(公告)日：2005-09-22
申请号：US11009364
申请日：2004-12-13
申请人： Stephane Commo , Bruno Bernard
发明人： Stephane Commo , Bruno Bernard
IPC分类号： A61K8/34 , A61K8/42 , A61K8/63 , A61K8/64 , A61K31/7048 , A61Q5/00 , A61Q5/06 , A61Q5/10 , A61Q7/00 , A61K7/135
CPC分类号： A61Q5/065 , A61K8/34 , A61K8/42 , A61K8/63 , A61K8/64 , A61K31/7048 , A61K2800/70 , A61Q5/00 , A61Q5/10 , A61Q7/00
摘要： Agents inducing the expression of DOPAchrome tautomerase are administered, notably topically applied, to protect and/or regenerate the melanocytes of hair follicles, to promote the cyclic renewal of the follicular pigmentation unit, to prevent and/or limit and/or arrest the development of canities, and to maintain the natural pigmentation of gray or white head hair and/or body hair.
摘要翻译：诱导诱导DOPAchrome互变异构酶表达的药剂，特别是局部施用，以保护和/或再生毛囊的黑素细胞，促进滤泡色素沉着单位的循环更新，以预防和/或限制和/或阻止并保持灰色或白色头发和/或身体毛发的天然色素沉着。

8. 发明申请

US20050137175A1 Use of ecdysteroids for preparing dermatological or cosmetological anti-hair loss compositions 审中-公开
标题翻译：使用蜕皮甾酮制备皮肤病学或美容抗脱发组合物
公开(公告)号：US20050137175A1
公开(公告)日：2005-06-23
申请号：US11017618
申请日：2004-12-20
申请人： Bruno Bernard , Brigitte Gautier
发明人： Bruno Bernard , Brigitte Gautier
IPC分类号： A61K8/00 , A61K8/49 , A61K8/63 , A61K31/505 , A61K31/56 , A61K31/575 , A61K31/70 , A61P17/14 , A61Q5/00 , A61Q7/00 , C07J9/00
CPC分类号： A61K8/63 , A61K31/70 , A61Q7/00
摘要： The present invention relates to the use of at least one ecdysteroid for preparing cosmetic or dermatological compositions intended to prevent hair loss.
摘要翻译：本发明涉及至少一种蜕皮甾酮用于制备旨在防止脱发的化妆品或皮肤病学组合物的用途。

9. 发明授权

US06541507B1 Indolecarboxylic compounds for inducing/stimulating hair growth and/or retarding hair loss 失效
标题翻译：用于诱导/刺激头发生长和/或减缓脱发的吲哚类化合物
公开(公告)号：US06541507B1
公开(公告)日：2003-04-01
申请号：US09617106
申请日：2000-07-14
申请人： Maria Dalko , Jean-Baptiste Galey , Bruno Bernard
发明人： Maria Dalko , Jean-Baptiste Galey , Bruno Bernard
IPC分类号： A61K3140
CPC分类号： A61Q7/00 , A61K8/492
摘要： Indolecarboxylic acid compounds and derivatives thereof, notably 4,6-dimethoxyindole-2-carboxylic acid and derivatives thereof, are especially useful for inducing/stimulating mammalian hair growth and/or preventing/retarding mammalian hair loss.
摘要翻译：吲哚羧酸化合物及其衍生物，特别是4,6-二甲氧基吲哚-2-羧酸及其衍生物，特别可用于诱导/刺激哺乳动物毛发生长和/或预防/延缓哺乳动物脱发。

10. 发明授权

US5702710A Dibenzofuran compounds and pharmaceutical/cosmetic compositions comprised thereof 失效
标题翻译：二苯并呋喃化合物和由其组成的药物/化妆品组合物
公开(公告)号：US5702710A
公开(公告)日：1997-12-30
申请号：US539222
申请日：1995-10-04
申请人： Bruno Charpentier , Michele Vion , Bruno Bernard , Jean Maignan
发明人： Bruno Charpentier , Michele Vion , Bruno Bernard , Jean Maignan
IPC分类号： A61K8/49 , A61K8/67 , A61K31/34 , A61Q7/00 , A61Q19/00 , C07D307/93 , C07D407/04 , A61K7/48 , C07D307/79
CPC分类号： C07D407/04 , A61K8/4973 , A61K8/671 , A61Q19/00 , C07D307/93 , A61Q17/04 , A61Q19/08 , A61Q7/00 , Y10S514/844 , Y10S514/846 , Y10S514/859 , Y10S514/886 , Y10S514/912 , Y10S514/937 , Y10S514/944
摘要： Novel pharmaceutically/cosmetically-active dibenzofuran compounds have the structural formula (I): ##STR1## wherein A is a radical having one of the formulae (IIa), (IIb) or (IIc): ##STR2## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.
摘要翻译：新的药物/化妆活性二苯并呋喃化合物具有结构式（I）：式（IIa），（IIb）或（IIc）：图像（IIa）（IIc）（IIb）可用于治疗各种疾病状态，无论是人类还是兽医，例如皮肤病学，风湿性，呼吸道，心血管和眼科疾病，以及用于治疗哺乳动物皮肤和毛发病症/病症。

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