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1. 发明申请

US20220126627A1 CONNECTED DEPLOYABLE ARMS OFF OF CYLINDRICAL SURFACES FOR INCREASED MOBILITY 有权
公开(公告)号：US20220126627A1
公开(公告)日：2022-04-28
申请号：US17429551
申请日：2020-02-14
申请人： Brigham Young University
发明人： Jacob Sheffield , Larry L. Howell , Kendall Hal Seymour
IPC分类号： B60B19/02 , B60B19/04 , B60B15/12 , E21B10/32 , B64C39/02
摘要： A method and apparatus for connected deployable arms off of cylindrical surfaces including an outer cylinder defining an outer circumference and an inner cylinder concentric with the outer cylinder around a central aperture, one or more primary developable mechanisms linked to one or more secondary developable mechanisms. The deployable arms transition from a first closed state wherein the primary developable mechanisms and secondary developable mechanisms are contained entirely within the outer cylinder outer circumference to a second open state wherein the inner cylinder rotates relative to the outer cylinder, forcing the primary developable mechanisms and secondary developable mechanisms to extend outside the outer cylinder outer circumference.

2. 发明申请

US20210252693A1 APPARATUS WITH MULTIPLE HINGEDLY COUPLED LINKS 有权
公开(公告)号：US20210252693A1
公开(公告)日：2021-08-19
申请号：US17250201
申请日：2019-06-17
申请人： BRIGHAM YOUNG UNIVERSITY
发明人： Larry L. Howell , Spencer T Magleby , Todd G. Nelson , Jacob R. Greenwood
IPC分类号： B25J9/00 , B25J9/10
摘要： An apparatus can comprise multiple links, the multiple links comprising at least a first link, a second link, a third link, and a base link, each of the multiple links comprising a rigid sheet, the first link being hingedly coupled to the second link via a first joint, the second link being hingedly coupled to the third link via a second joint, the third link being hingedly coupled to the base link via a third joint, the base link being hingedly coupled to the first link via a fourth joint. The multiple links defining at least a portion of a cylinder when the apparatus is in a stowed position, the first joint, second joint, third joint, and fourth joint being aligned parallel to each other and aligned parallel to a longitudinal axis of the cylinder.

3. 发明授权

US10398842B2 Rectangular syringe 有权
公开(公告)号：US10398842B2
公开(公告)日：2019-09-03
申请号：US15445377
申请日：2017-02-28
申请人： Brigham Young University
发明人： Jeffrey E. Niven , Jason Dearden , Peter S. Schleede , Andrew J. Moulton , Larry L. Howell , Spencer P. Magleby
IPC分类号： A61M5/32 , A61M5/20 , A61M5/31 , A61M5/46
摘要： An auto-injection syringe shaped similar to a credit card and having a biased injection mechanism operable to drive a needle into a user's body by a fixed distance to dispense a dose of fluid at a subcutaneous location. A safety may be provided to avoid undesired actuation of the injection mechanism. After the safety is bypassed, a trigger may be actuated by the user to allow operation of the injection mechanism. A reciprocating needle-cover resists casual view of the needle by the user during and after use of the syringe. A locking mechanism automatically holds the needle-cover at an extended position to isolate the needle from further contact and to resist re-use of the syringe.

4. 发明申请

US20150075583A1 FOLDABLE ARRAY OF THREE-DIMENSIONAL PANELS INCLUDING FUNCTIONAL ELECTRICAL COMPONENTS 有权
标题翻译：三维面板的可折叠阵列，包括功能电气部件
公开(公告)号：US20150075583A1
公开(公告)日：2015-03-19
申请号：US14484006
申请日：2014-09-11
申请人： BRIGHAM YOUNG UNIVERSITY
发明人： Kevin Campbell Francis , Cory Nelson Newton , Mary E. Wilson , Shannon Alisa Zirbel , Spencer P. Magleby , Larry L. Howell
IPC分类号： H02S30/20 , H01L31/02
CPC分类号： H02S30/20 , H01L31/0201 , Y02E10/50
摘要： Embodiments disclosed herein relate to a foldable array of three-dimensional panels, which may include one or more functional electrical components. For instance, the three-dimensional multi-panel array may be reconfigured from a substantially planar configuration into a three-dimensional configuration.
摘要翻译：本文公开的实施例涉及三维面板的可折叠阵列，其可以包括一个或多个功能性电气部件。例如，三维多面板阵列可以从基本上平面的配置重新配置成三维配置。

5. 发明申请

US20130177988A1 CYTOPLASM TO ORGANELLE DELIVERY SYSTEM AND ASSOCIATED METHODS 审中-公开
标题翻译： CYTOPLASM到ORGANELLE交付系统和相关方法
公开(公告)号：US20130177988A1
公开(公告)日：2013-07-11
申请号：US13681260
申请日：2012-11-19
申请人： Brigham Young University
发明人： Quentin T. Aten , Regis A. David , Sandra H. Burnett , Brian D. Jensen , Larry L. Howell
IPC分类号： C12N13/00
CPC分类号： C12N15/8775 , C12N13/00 , C12N15/89
摘要： Systems, devices, and methods for delivering a biological material into an organelle of a cell are provided. In one aspect, for example, a method for introducing biological material into an organelle of a cell can include bringing into proximity outside of a cell a lance and a preselected biological material, charging the lance with a polarity and a charge sufficient to electrically associate the preselected biological material with a tip portion of the lance, and penetrating an outer portion of the cell with the lance and directing and inserting the lance into the cell but outside of the organelle. The method can further include discharging the lance to release at least a portion of the biological material, charging the lance with an opposite polarity and charge sufficient to electrophoretically drive at least a portion of the biological material into the organelle, and withdrawing the lance from the cell.
摘要翻译：提供了将生物材料递送到细胞的细胞器中的系统，装置和方法。在一个方面，例如，将生物材料引入细胞的细胞器的方法可以包括使细胞附着在喷枪和预选的生物材料的外部，用足够的极性和电荷对喷枪进行充电以电连接预先选择的具有喷枪的尖端部分的生物材料，并且用喷枪穿透细胞的外部部分并且将喷枪引导并插入细胞中，但是在细胞器外部。该方法还可以包括排出喷枪以释放生物材料的至少一部分，以相反的极性对喷枪进行充电，并充入足以将至少一部分生物材料电泳驱动到细胞器中，并将枪从细胞。

6. 发明申请

US20220032485A1 DEVELOPABLE AND COLLAPSABLE EXTERNAL CUTTING OR GRIPPING MECHANISM 有权
公开(公告)号：US20220032485A1
公开(公告)日：2022-02-03
申请号：US17277014
申请日：2019-09-18
申请人： Brigham Young University
发明人： Lance Hyatt , Jacob Sheffield , Kendall Hal Seymour , Scott Cunnington , Spencer Magleby , Larry L. Howell
IPC分类号： B26B27/00
摘要： A hollow rod developable actuator tool including a cylinder defining the outer circumference of the hollow rod, a first tool mechanism, and a second tool mechanism. The hollow rod developable actuator tool transitions from a first closed state wherein the first tool mechanism and second tool mechanism are contained entirely within the outer circumference of the hollow rod to a second open state wherein the first tool mechanism and second tool mechanism extent outside the outer circumference of the hollow rod.

7. 发明授权

US10119151B2 Methods and devices for charged molecule manipulation 有权
公开(公告)号：US10119151B2
公开(公告)日：2018-11-06
申请号：US14103618
申请日：2013-12-11
申请人： Brigham Young University
发明人： Quentin T. Aten , Larry L. Howell , Brian D. Jensen , Sandra Burnett
IPC分类号： C12N15/89 , C12M1/42
摘要： Systems and methods for manipulating molecular material are provided. In one aspect, for example, a method for manipulating molecular material may include positioning an uncharged needle structure in electrical proximity with a charged molecular material at a first locus in a liquid environment, charging the needle structure such that at least a portion of the charged molecular material becomes associated with the needle structure, moving the needle structure and the first locus relative to one another, and discharging the needle structure to disassociate the charged molecular material at a second locus.

8. 发明申请

US20180243506A1 RECTANGULAR SYRINGE 审中-公开
公开(公告)号：US20180243506A1
公开(公告)日：2018-08-30
申请号：US15445377
申请日：2017-02-28
申请人： Brigham Young University
发明人： Jeffrey E. Niven , Jason Dearden , Peter S. Schleede , Andrew J. Moulton , Larry L. Howell , Spencer P. Magleby
IPC分类号： A61M5/31 , A61M5/20 , A61M5/32 , A61M5/46
CPC分类号： A61M5/3129 , A61M5/2033 , A61M5/3234 , A61M5/326 , A61M5/3287 , A61M5/46 , A61M2005/2026 , A61M2005/206 , A61M2005/314 , A61M2205/273 , A61M2205/276
摘要： An auto-injection syringe shaped similar to a credit card and having a biased injection mechanism operable to drive a needle into a user's body by a fixed distance to dispense a dose of fluid at a subcutaneous location. A safety may be provided to avoid undesired actuation of the injection mechanism. After the safety is bypassed, a trigger may be actuated by the user to allow operation of the injection mechanism. A reciprocating needle-cover resists casual view of the needle by the user during and after use of the syringe. A locking mechanism automatically holds the needle-cover at an extended position to isolate the needle from further contact and to resist re-use of the syringe.

9. 发明授权

US09512618B2 Rigidly foldable array of three-dimensional bodies 有权
标题翻译：三维体的刚性可折叠阵列
公开(公告)号：US09512618B2
公开(公告)日：2016-12-06
申请号：US14548148
申请日：2014-11-19
申请人： BRIGHAM YOUNG UNIVERSITY
发明人： Robert J. Lang , Bryce J. Edmondson , Spencer P. Magleby , Larry L. Howell
IPC分类号： E04C2/40 , F24J2/36 , F24J2/52 , F24J2/54
CPC分类号： E04C2/405 , F24S20/50 , F24S2025/012 , F24S2030/136 , Y02E10/40 , Y10T428/19
摘要： Rigidly foldable, foldable multi-body arrays or systems that may include three-dimensional bodies connected together by multiple hinges and reconfigurable between unfolded and folded configurations.
摘要翻译：刚性可折叠，可折叠的多体阵列或系统，其可包括通过多个铰链连接在一起的三维体，并可在展开和折叠构型之间重构。

10. 发明申请

US20140199765A1 LANCE DEVICE AND ASSOCIATED METHODS FOR DELIVERING A BIOLOGICAL MATERIAL INTO A CELL 审中-公开
标题翻译： LANCE设备和将生物材料递送到细胞中的相关方法
公开(公告)号：US20140199765A1
公开(公告)日：2014-07-17
申请号：US14109668
申请日：2013-12-17
申请人： Brigham Young University
发明人： Quentin T. Aten , Sandra H. Burnett , Brian D. Jensen , Larry L. Howell
IPC分类号： C12N15/89
CPC分类号： C12N15/89 , C12M35/00
摘要： Systems, devices, and methods for delivering a biological material into a cell are provided. In one example, a lance device for introducing biological material into a cell and configured for use in a nanoinjection system including a microscope is provided. Such a device can include a lance having a tip region and a shaft region, wherein the lance is structurally configured to allow entry and movement of the tip region into the cell along an elongate axis of the tip region and along a focal plane of the microscope. In another example, the lance can be configured to allow substantially horizontal entry and movement of the tip region into the cell.
摘要翻译：提供了将生物材料递送到电池中的系统，装置和方法。在一个示例中，提供了用于将生物材料引入细胞并配置用于包括显微镜的纳米注射系统中的喷枪装置。这种装置可以包括具有尖端区域和轴区域的喷枪，其中喷枪在结构上构造成允许尖端区域沿着尖端区域的细长轴线并沿着显微镜的焦平面进入和移动到细胞中。在另一示例中，喷枪可以被配置为允许尖端区域基本上水平地进入和移动到电池中。

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