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1. 发明申请

US20060184094A1 Localized fluid delivery devices having a porous applicator and methods for using the same 审中-公开
公开(公告)号：US20060184094A1
公开(公告)日：2006-08-17
申请号：US11318049
申请日：2005-12-22
申请人： Brent Constantz , Jerome Riebman , Philip Houle
发明人： Brent Constantz , Jerome Riebman , Philip Houle
IPC分类号： A61B17/20
CPC分类号： A61B17/22 , A61B2017/22082 , A61B2017/22084 , A61B2017/22097 , A61B2017/22098 , A61B2217/005 , A61M1/008 , A61M25/00 , A61M2025/0004 , A61M2025/0036 , A61M2025/0039 , A61M2025/004 , A61M2025/0057 , A61M2210/125
摘要： Fluid delivery devices having a porous applicator, as well as methods for using the same in the highly localized delivery of fluid to a target site, are provided. The subject devices have a porous applicator through which fluid must flow in order to contact the target delivery site. The subject devices find use in a variety of fluid delivery applications in which the localized delivery of a fluid to a target site is desired. Also provided are systems and kits that include the subject fluid delivery devices.

2. 发明申请

US20050215949A1 Multichannel catheter 失效
标题翻译：多通道导管
公开(公告)号：US20050215949A1
公开(公告)日：2005-09-29
申请号：US11132916
申请日：2005-05-18
申请人： Arthur Bertolero , Raymond Bertolero , Jerome Riebman
发明人： Arthur Bertolero , Raymond Bertolero , Jerome Riebman
IPC分类号： A61B1/05 , A61B1/313 , A61B17/00 , A61B17/02 , A61B17/04 , A61B17/28 , A61B17/32 , A61B17/80 , A61B19/00 , A61B19/08 , A61F2/958 , A61M1/36 , A61M25/00 , A61M29/00 , A61M29/02
CPC分类号： A61B17/29 , A61B1/05 , A61B1/313 , A61B17/00234 , A61B17/0206 , A61B17/2812 , A61B17/320016 , A61B17/8085 , A61B46/10 , A61B90/36 , A61B90/37 , A61B90/50 , A61B2017/00199 , A61B2017/00243 , A61B2017/0046 , A61B2017/00557 , A61B2017/2904 , A61B2017/2905 , A61B2017/2946 , A61M1/3659 , A61M25/0029 , A61M25/003 , A61M25/0032 , A61M25/10 , A61M25/1027 , A61M2025/0031 , A61M2025/1052 , A61M2025/1086 , A61M2025/1097 , A61M2210/127
摘要： A single, multichannel catheter for extracorporeal circulation of blood to a patient undergoing cardiac treatments or surgery. The catheter has three independent channels and an expandable balloon. The first channel is the largest and delivers blood to a patient to maintain the patient's metabolism and perfusion throughout the treatment or surgery. A second, smaller channel is integrated into the wall of the first channel and delivers a biologically active fluid (e.g., for cardioplegia) to the heart and/or venting the left heart. A third, smaller channel is integrated into the wall of the first channel, and delivers an expansion fluid to the balloon to occlude the flow of blood to the heart. Preferably, the first channel accounts for at least about 70% of the total channel volume. The multichannel catheter is best prepared using an extrusion molding technique.
摘要翻译：一种用于体外循环血液的单通道导管，用于接受心脏治疗或手术的患者。导管具有三个独立的通道和可扩张的气囊。第一个通道是最大的，并向患者输送血液，以在整个治疗或手术中维持患者的新陈代谢和灌注。第二个更小的通道被集成到第一通道的壁中并将生物活性流体（例如，用于心麻痹）递送到心脏和/或排出左心脏。第三个更小的通道被集成到第一通道的壁中，并且将膨胀流体输送到气囊以将血流封闭到心脏。优选地，第一通道占总通道容积的至少约70％。多通道导管最好使用挤出成型技术制备。

3. 发明申请

US20060149187A1 Multichannel catheter with obturator 有权
标题翻译：带通孔的多通道导管
公开(公告)号：US20060149187A1
公开(公告)日：2006-07-06
申请号：US11029820
申请日：2005-01-03
申请人： Arthur Bertolero , Raymond Bertolero , Jerome Riebman
发明人： Arthur Bertolero , Raymond Bertolero , Jerome Riebman
IPC分类号： A61M29/00
CPC分类号： A61M25/003 , A61M25/0032 , A61M25/007 , A61M25/10 , A61M2025/0031 , A61M2025/1052
摘要： A multichannel catheter for extracorporeal circulation of blood to a patient undergoing cardiovascular treatments or surgery has three independent channels, an obturator and an expandable balloon. The first channel is the largest and is of a size that allows for delivery of blood through outlet parts in the wall of the first channel to a patient in an amount sufficient to maintain the patient's metabolism and perfusion throughout the treatment or surgery. The obturator is longitudinally insertable into the first channel. The second and third channels are integrated into the wall of the first channel. The second channel is suitable for delivering a biologically active fluid to the heart and/or venting the left heart. The third channel is suitable for delivering a fluid to the balloon for its expansion. The catheter provides an improved means of preparing for or performing cardiovascular surgery on a patient using a cardiopulmonary machine for extracorporeal circulation of blood.
摘要翻译：用于体外血液循环到经历心血管治疗或手术的患者的多通道导管具有三个独立的通道，一个闭孔器和一个可扩张的气囊。第一个通道是最大的，并且具有允许通过第一通道的壁中的出口部分向患者输送足以在整个治疗或手术中维持患者的新陈代谢和灌注的量的尺寸。封闭器可纵向插入第一通道。第二和第三通道被集成到第一通道的壁中。第二通道适于将生物活性流体输送到心脏和/或排出左心脏。第三个通道适用于将流体输送到球囊进行扩张。该导管提供了一种用于使用心肺机器进行血液体外循环来为患者准备或进行心血管手术的改进方法。

4. 发明申请

US20050148810A1 Devices and methods for blood flow assistance 失效
标题翻译：用于血液流动辅助的装置和方法
公开(公告)号：US20050148810A1
公开(公告)日：2005-07-07
申请号：US10751405
申请日：2004-01-06
申请人： Jerome Riebman , Kevin Ohashi
发明人： Jerome Riebman , Kevin Ohashi
IPC分类号： A61M1/10 , A61M1/12 , A61N1/362
CPC分类号： A61M1/107 , A61M1/1008 , A61M1/1037 , A61M1/106 , A61M1/122
摘要： Devices and methods are disclosed for assisting in blood flow from a weakened or injured heart, particularly for pediatric patients. A low profile, multi-chambered implantable mechanism is used to collect blood from a blood vessel and re-pump the blood out with an induced pressure emanating from a fluid pressure source. The devices and methods described herein are easy to use and may be attachable to body tissue without use of suture anastomosis.
摘要翻译：公开了用于帮助来自弱化或受伤的心脏，特别是儿科患者的血液流动的装置和方法。使用低剖面多腔植入机构从血管收集血液，并用从流体压力源发出的诱导压力重新泵送血液。本文描述的装置和方法易于使用，并且可以附接到身体组织而不使用缝合吻合。

5. 发明申请

US20130084323A1 FENESTRATED HEMOSTATIC PATCH 审中-公开
标题翻译：精密麻醉贴
公开(公告)号：US20130084323A1
公开(公告)日：2013-04-04
申请号：US13625968
申请日：2012-09-25
申请人： Jerome Riebman , Jeffrey Hammond , Kevin Weadock , John P. Matonick
发明人： Jerome Riebman , Jeffrey Hammond , Kevin Weadock , John P. Matonick
IPC分类号： A61K9/70 , A61F13/02 , C07K14/78 , A61K38/39 , A61P7/04
CPC分类号： A61L26/0042 , A61L15/64 , A61L26/0047 , A61L26/0066 , A61L26/009 , A61L2300/252 , A61L2300/254 , A61L2300/418 , A61L2300/608 , A61L2400/04
摘要： A hemostat comprises a non-porous patch made of a bio-resorbable tissue compatible material, said patch having a tissue-facing surface and a top surface; an optional hemostatic agent that is disposed on said tissue-facing surface or optionally dispersed throughout said patch or optionally as a separate carrier layer, and at least one aperture or slit that penetrates said patch at least partially from said tissue-facing surface to said top surface.
摘要翻译：止血剂包括由生物可再吸收的组织相容材料制成的无孔贴片，所述贴片具有面向组织的表面和顶表面; 可选的止血剂，其设置在所述面向组织的表面上或任选地分散在整个所述贴剂中或任选地分散在单独的载体层中，以及至少一个孔或狭缝，其至少部分地从所述面向组织的表面渗透至所述顶部表面。

6. 发明申请

US20060199993A1 Devices and methods for blood flow assistance 审中-公开
标题翻译：用于血液流动辅助的装置和方法
公开(公告)号：US20060199993A1
公开(公告)日：2006-09-07
申请号：US11429187
申请日：2006-05-08
申请人： Jerome Riebman , Kevin Ohashi
发明人： Jerome Riebman , Kevin Ohashi
IPC分类号： A61N1/362
CPC分类号： A61M1/107 , A61M1/1008 , A61M1/1037 , A61M1/106 , A61M1/122
摘要： Devices and methods are disclosed for assisting in blood flow from a weakened or injured heart, particularly for pediatric patents. A low profile, multi-chambered implantable mechanism is used to collect blood from a blood vessel and re-pump the blood out with an induced pressure emanating from a fluid pressure source. The devices and methods described herein are easy to use and may be attachable to body tissue without use of suture anastomosis.
摘要翻译：公开了用于帮助来自弱化或受伤的心脏，特别是儿科专利的血液流动的装置和方法。使用低剖面多腔植入机构从血管收集血液，并用从流体压力源发出的诱导压力重新泵送血液。本文描述的装置和方法易于使用，并且可以附接到身体组织而不使用缝合吻合。

7. 发明授权

US09132040B2 Dressing device 有权
标题翻译：敷料装置
公开(公告)号：US09132040B2
公开(公告)日：2015-09-15
申请号：US13298495
申请日：2011-11-17
申请人： Robert W. Van Holten , Xintian Ming , Jerome Riebman
发明人： Robert W. Van Holten , Xintian Ming , Jerome Riebman
IPC分类号： A61L15/16 , A61K9/70 , A61F13/00 , A61K31/155 , A01N25/04 , A01N25/34 , A01N31/02
CPC分类号： A61F13/00063 , A01N25/04 , A01N25/34 , A01N31/02 , A61F13/00021 , A61F2013/00182 , A61K31/155 , A01N31/16 , A01N33/12 , A01N43/40 , A01N43/50 , A01N47/44 , A01N59/12 , A01N59/16
摘要： The invention relates to a transparent, absorbent device for the dressing of wounds and insertion sites of percutaneous and drug delivery devices. The device provides 360 degree or complete circumferential protection of a wound or insertion site of a percutaneous or drug delivery device and comprises a hydrogel center and at least one absorbent material. The hydrogel center can optionally comprise a bioactive agent(s).
摘要翻译：本发明涉及一种用于修复经皮和药物递送装置的伤口和插入部位的透明吸收装置。该装置提供经皮或药物递送装置的伤口或插入部位的360度或完整的圆周保护，并且包括水凝胶中心和至少一种吸收材料。水凝胶中心可任选地包含生物活性剂。

8. 发明申请

US20130131621A1 DRESSING DEVICE 有权
标题翻译：连接装置
公开(公告)号：US20130131621A1
公开(公告)日：2013-05-23
申请号：US13298495
申请日：2011-11-17
申请人： Robert W. Van Holten , Xintian Ming , Jerome Riebman
发明人： Robert W. Van Holten , Xintian Ming , Jerome Riebman
IPC分类号： A61F13/53 , A61K31/08 , A61P17/02 , A01N25/08 , A01P1/00 , A61K9/70 , A01N47/44
CPC分类号： A61F13/00063 , A01N25/04 , A01N25/34 , A01N31/02 , A61F13/00021 , A61F2013/00182 , A61K31/155 , A01N31/16 , A01N33/12 , A01N43/40 , A01N43/50 , A01N47/44 , A01N59/12 , A01N59/16
摘要： The invention relates to a transparent, absorbent device for the dressing of wounds and insertion sites of percutaneous and drug delivery devices. The device provides 360 degree or complete circumferential protection of a wound or insertion site of a percutaneous or drug delivery device and comprises a hydrogel center and at least one absorbent material. The hydrogel center can optionally comprise a bioactive agent(s).
摘要翻译：本发明涉及一种用于修复经皮和药物递送装置的伤口和插入部位的透明吸收装置。该装置提供经皮或药物递送装置的伤口或插入部位的360度或完整的圆周保护，并且包括水凝胶中心和至少一种吸收材料。水凝胶中心可任选地包含生物活性剂。

9. 发明申请

US20050267336A1 Surgical retractor and stabilizing device and method for use 审中-公开
标题翻译：手术牵开器及稳定装置及其使用方法
公开(公告)号：US20050267336A1
公开(公告)日：2005-12-01
申请号：US11122272
申请日：2005-05-03
申请人： Arthur Bertolero , Raymond Bertolero , Jerome Riebman
发明人： Arthur Bertolero , Raymond Bertolero , Jerome Riebman
IPC分类号： A61B1/05 , A61B1/313 , A61B1/32 , A61B17/00 , A61B17/02 , A61B17/04 , A61B17/28 , A61B17/32 , A61B17/80 , A61B19/00 , A61B19/08 , A61M1/36 , A61M25/00 , A61M29/02
CPC分类号： A61B17/29 , A61B1/05 , A61B1/313 , A61B1/32 , A61B17/00234 , A61B17/0206 , A61B17/2812 , A61B17/320016 , A61B17/8085 , A61B46/10 , A61B90/36 , A61B90/37 , A61B90/50 , A61B2017/00199 , A61B2017/00243 , A61B2017/0046 , A61B2017/2904 , A61B2017/2905 , A61B2017/2946 , A61M1/3659 , A61M25/0026 , A61M25/1027 , A61M2025/1052 , A61M2025/1086 , A61M2025/1097 , A61M2210/127
摘要： An adjustable surgical retractor and its use for improving a surgeon's ability to perform closed-chest video-assisted exploratory, diagnostic or surgical procedures on a patient. The surgical retractor has opposable blades which can be inserted into a surgical incision in a patient undergoing a surgical procedure then spread apart to form an elongated access opening through which a instrument may be inserted to perform exploratory, diagnostic or surgical procedures. The blades used in the surgical retractor may be flexible or rigid and are attachable to the retractor. The blades are of a width, depth and thickness to provide an access to an internal cavity or subcutaneous region to allow greater degrees of freedom to the surgeon in inserting instruments into the access opening. The use of the surgical retractor forms a substantially ovoid channel, through which a medical instrument can be inserted to perform surgical or other operations.
摘要翻译：可调节的手术牵开器及其用于改善外科医生对患者执行闭胸视频辅助探查，诊断或外科手术的能力。手术牵开器具有可对置的刀片，其可以插入经历外科手术的患者的手术切口中，然后分开形成细长的进入开口，通过该进口可以插入器械以执行探查，诊断或外科手术。在外科牵开器中使用的刀片可以是柔性的或刚性的，并且可附接到牵开器。刀片具有宽度，深度和厚度，以提供对内腔或皮下区域的访问，以允许外科医生在将仪器插入进入开口时获得更大程度的自由度。手术牵开器的使用形成基本上卵形的通道，通过该通道可以插入医疗器械以执行外科手术或其他手术。

10. 发明申请

US20050171505A1 Multichannel catheter 有权
标题翻译：多通道导管
公开(公告)号：US20050171505A1
公开(公告)日：2005-08-04
申请号：US10996876
申请日：2004-11-23
申请人： Arthur Bertolero , Raymond Bertolero , Jerome Riebman
发明人： Arthur Bertolero , Raymond Bertolero , Jerome Riebman
IPC分类号： A61F2/958 , A61B1/05 , A61B1/313 , A61B17/00 , A61B17/02 , A61B17/04 , A61B17/28 , A61B17/32 , A61B17/80 , A61B19/00 , A61B19/08 , A61M1/36 , A61M25/00 , A61M29/02 , A61M31/00
CPC分类号： A61B17/29 , A61B1/05 , A61B1/313 , A61B17/00234 , A61B17/0206 , A61B17/2812 , A61B17/320016 , A61B17/8085 , A61B46/10 , A61B90/36 , A61B90/37 , A61B90/50 , A61B2017/00199 , A61B2017/00243 , A61B2017/0046 , A61B2017/2904 , A61B2017/2905 , A61B2017/2946 , A61M1/3659 , A61M25/0029 , A61M25/0032 , A61M25/1027 , A61M2025/0031 , A61M2025/1052 , A61M2025/1086 , A61M2025/1097 , A61M2210/127
摘要： This invention is a single, multichannel catheter useful for extracorporeal circulation of blood to a patient undergoing cardiovascular treatments or surgery. The catheter has three independent channels and an expandable balloon at one end of the catheter. The first channel (34) is the largest and is of a size that allows for delivery of blood to a patient in an amount sufficient to maintain the patient's metabolism and perfusion throughout the treatment or surgery. A second channel (36), smaller than the first, is integrated into the wall of the first channel, and is suitable for delivering a biologically active fluid (e.g., for cardioplegia) to the heart and/or venting the left heart. A third channel (38), also smaller than the first, is integrated into the wall of the first channel, and suitable for delivering a fluid to the balloon for its expansion when positioned in the ascending aorta to occlude the flow of blood to the heart. It is important that the first channel accounts for at least about 70% of the total channel volume. The catheter provides an improved means of performing cardiovascular surgery on a patient using a cardiopulmonary machine for extracorporeal circulation of blood. The catheter is particularly useful for cardiac surgery. The multichannel catheter is best prepared using an extrusion molding technique.
摘要翻译：本发明是用于经历心血管治疗或手术的患者的体外血液循环的单通道多通道导管。导管具有三个独立的通道和在导管的一端的可膨胀气囊。第一通道（34）是最大的，并且具有允许以足以在整个治疗或手术中维持患者的新陈代谢和灌注的量向患者输送血液的尺寸。小于第一通道的第二通道（36）被集成到第一通道的壁中，并且适于将生物活性流体（例如用于心脏停跳）输送到心脏和/或排出左心脏。也比第一通道小的第三通道（38）被集成到第一通道的壁中，并且适合于当定位在升主动脉中时将流体输送到球囊以用于其膨胀，以将血液流动阻塞到心脏。重要的是，第一个频道占通道总容量的至少约70％。该导管提供了一种使用心肺机器对血液进行体外循环的患者进行心血管手术的改进方法。导管对于心脏手术特别有用。多通道导管最好使用挤出成型技术制备。

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