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1. 发明申请

US20050084474A1 Method for reducing odor using coordinated polydentate compounds 失效
标题翻译：使用配位多齿化合物降低气味的方法
公开(公告)号：US20050084474A1
公开(公告)日：2005-04-21
申请号：US10686937
申请日：2003-10-16
申请人： Bin Wu , Kevin McGrath , Jaeho Kim , Bao Do , Sharon Greene , Yanbin Huang , Kaiyuan Yang
发明人： Bin Wu , Kevin McGrath , Jaeho Kim , Bao Do , Sharon Greene , Yanbin Huang , Kaiyuan Yang
IPC分类号： A61L9/014 , A61L15/46 , D21H21/14 , A61K7/04 , A61L9/00 , A61L9/01
CPC分类号： D21H21/14 , A61L9/014 , A61L15/46 , A61L2300/102 , A61L2300/802
摘要： A method for reducing odor is provided. The method comprises forming a coordination complex between a transition metal and a polydentate compound, and contacting the coordinated complex with an odorous compound. The transition metal provides one or more active sites for capturing the odorous compound. In some embodiments, the polydentate compound may be a polyalkylimine, such as polyethyleneimine, polypropyleneimine, or a dendrimer thereof.
摘要翻译：提供了减少气味的方法。该方法包括在过渡金属和多齿化合物之间形成配位络合物，并使配位络合物与有气味化合物接触。过渡金属提供了一个或多个用于捕获有气味化合物的活性位点。在一些实施方案中，多齿化合物可以是聚烷基亚胺，例如聚乙烯亚胺，聚丙烯亚胺或其树枝状大分子。

2. 发明申请

US20100275915A1 METHOD FOR REDUCING ODOR USING COORDINATED POLYDENTATE COMPOUNDS 失效
标题翻译：使用协调的聚氨酯化合物减少气味的方法
公开(公告)号：US20100275915A1
公开(公告)日：2010-11-04
申请号：US12835418
申请日：2010-07-13
申请人： Bin Wu , Kevin P. McGrath , Jaeho Kim , Bao Trong Do , Sharon Linda Greene , Yanbin Huang , Kaiyuan Yang
发明人： Bin Wu , Kevin P. McGrath , Jaeho Kim , Bao Trong Do , Sharon Linda Greene , Yanbin Huang , Kaiyuan Yang
IPC分类号： A61L15/46 , A61L9/01 , A61L9/012 , C08F8/42 , A61M16/06
CPC分类号： D21H21/14 , A61L9/014 , A61L15/46 , A61L2300/102 , A61L2300/802
摘要： A method for reducing odor is provided. The method comprises forming a coordination complex between a transition metal and a polydentate compound, and contacting the coordinated complex with an odorous compound. The transition metal provides one or more active sites for capturing the odorous compound. In some embodiments, the polydentate compound may be a polyalkylimine, such as polyethyleneimine, polypropyleneimine, or a dendrimer thereof.
摘要翻译：提供了减少气味的方法。该方法包括在过渡金属和多齿化合物之间形成配位络合物，并使配位络合物与有气味化合物接触。过渡金属提供了一个或多个用于捕获有气味化合物的活性位点。在一些实施方案中，多齿化合物可以是聚烷基亚胺，例如聚乙烯亚胺，聚丙烯亚胺或其树枝状大分子。

3. 发明授权

US08178081B2 Method for reducing odor using coordinated polydentate compounds 失效
标题翻译：使用配位多齿化合物降低气味的方法
公开(公告)号：US08178081B2
公开(公告)日：2012-05-15
申请号：US12835418
申请日：2010-07-13
申请人： Bin Wu , Kevin P. McGrath , Jaeho Kim , Bao Trong Do , Sharon Linda Greene , Yanbin Huang , Kaiyuan Yang
发明人： Bin Wu , Kevin P. McGrath , Jaeho Kim , Bao Trong Do , Sharon Linda Greene , Yanbin Huang , Kaiyuan Yang
IPC分类号： A61L15/46 , A61L9/01 , A61L9/12 , C08F8/42 , A61M16/06
CPC分类号： D21H21/14 , A61L9/014 , A61L15/46 , A61L2300/102 , A61L2300/802
摘要： A method for reducing odor is provided. The method comprises forming a coordination complex between a transition metal and a polydentate compound, and contacting the coordinated complex with an odorous compound. The transition metal provides one or more active sites for capturing the odorous compound. In some embodiments, the polydentate compound may be a polyalkylimine, such as polyethyleneimine, polypropyleneimine, or a dendrimer thereof.
摘要翻译：提供了减少气味的方法。该方法包括在过渡金属和多齿化合物之间形成配位络合物，并使配位络合物与有气味化合物接触。过渡金属提供了一个或多个用于捕获有气味化合物的活性位点。在一些实施方案中，多齿化合物可以是聚烷基亚胺，例如聚乙烯亚胺，聚丙烯亚胺或其树枝状大分子。

4. 发明授权

US07754197B2 Method for reducing odor using coordinated polydentate compounds 失效
标题翻译：使用配位多齿化合物降低气味的方法
公开(公告)号：US07754197B2
公开(公告)日：2010-07-13
申请号：US10686937
申请日：2003-10-16
申请人： Bin Wu , Kevin P. McGrath , Jaeho Kim , Bao Trong Kim , Sharon Linda Greene , Yanbin Huang , Kaiyuan Yang
发明人： Bin Wu , Kevin P. McGrath , Jaeho Kim , Bao Trong Kim , Sharon Linda Greene , Yanbin Huang , Kaiyuan Yang
IPC分类号： B01D53/34 , A01N59/00 , A01N59/16 , A01N59/20 , A61K33/00 , A61K33/38 , A61K33/34 , A61K33/32 , A61K33/26 , A61K33/24
CPC分类号： D21H21/14 , A61L9/014 , A61L15/46 , A61L2300/102 , A61L2300/802
摘要： A method for reducing odor is provided. The method comprises forming a coordination complex between a transition metal and a polydentate compound, and contacting the coordinated complex with an odorous compound. The transition metal provides one or more active sites for capturing the odorous compound. In some embodiments, the polydentate compound may be a polyalkylimine, such as polyethyleneimine, polypropyleneimine, or a dendrimer thereof.
摘要翻译：提供了减少气味的方法。该方法包括在过渡金属和多齿化合物之间形成配位络合物，并使配位络合物与有气味化合物接触。过渡金属提供了一个或多个用于捕获有气味化合物的活性位点。在一些实施方案中，多齿化合物可以是聚烷基亚胺，例如聚乙烯亚胺，聚丙烯亚胺或其树枝状大分子。

5. 发明申请

US20050049157A1 Single phase color change agents 有权
标题翻译：单相变色剂
公开(公告)号：US20050049157A1
公开(公告)日：2005-03-03
申请号：US10651421
申请日：2003-08-29
申请人： John MacDonald , Yanbin Huang , Kaiyuan Yang , Jaeho Kim , Ning Wei
发明人： John MacDonald , Yanbin Huang , Kaiyuan Yang , Jaeho Kim , Ning Wei
IPC分类号： C11D3/00 , C11D3/22 , C11D3/40 , C11D1/00 , A61K7/50
CPC分类号： C11D3/221 , C11D3/0042 , C11D3/40
摘要： There is provided a color change composition that remains stable in a single phase and that contains an indicator that produces an observable color change after a period of time to show that sufficient cleaning has been done or to indicate the thoroughness of the cleaning. This use indicating color change is useful for, for example, in soap for teaching children to wash their hands for a sufficient period of time. This composition may be added to many different base materials to indicate time of use or as a way to introduce enjoyment to the activity.
摘要翻译：提供了颜色变化组合物，其在单一相中保持稳定，并且包含在一段时间之后产生可观察到的颜色变化的指示剂，以显示已经进行足够的清洁或指示清洁的彻底性。指示颜色变化的这种用途对于例如在肥皂中教孩子们洗手足够长时间是有用的。这种组合物可以添加到许多不同的基础材料中以指示使用时间或作为向活动引入享受的方式。

6. 发明授权

US07651989B2 Single phase color change agents 有权
公开(公告)号：US07651989B2
公开(公告)日：2010-01-26
申请号：US10651421
申请日：2003-08-29
申请人： John Gavin MacDonald , Yanbin Huang , Kaiyuan Yang , Jaeho Kim , Ning Wei
发明人： John Gavin MacDonald , Yanbin Huang , Kaiyuan Yang , Jaeho Kim , Ning Wei
IPC分类号： A61K7/00
CPC分类号： C11D3/221 , C11D3/0042 , C11D3/40
摘要： There is provided a color change composition that remains stable in a single phase and that contains an indicator that produces an observable color change after a period of time to show that sufficient cleaning has been done or to indicate the thoroughness of the cleaning. This use indicating color change is useful for, for example, in soap for teaching children to wash their hands for a sufficient period of time. This composition may be added to many different base materials to indicate time of use or as a way to introduce enjoyment to the activity.

7. 发明申请

US20100120644A1 Single Phase Color Change Agents 有权
标题翻译：单相变色剂
公开(公告)号：US20100120644A1
公开(公告)日：2010-05-13
申请号：US12692003
申请日：2010-01-22
申请人： John Gavin MacDonald , Yanbin Huang , Kaiyuan Yang , Jaeho Kim , Ning Wei
发明人： John Gavin MacDonald , Yanbin Huang , Kaiyuan Yang , Jaeho Kim , Ning Wei
IPC分类号： C11D3/40
CPC分类号： C11D3/221 , C11D3/0042 , C11D3/40
摘要： There is provided a color change composition that remains stable in a single phase and that contains an indicator that produces an observable color change after a period of time to show that sufficient cleaning has been done or to indicate the thoroughness of the cleaning. This use indicating color change is useful for, for example, in soap for teaching children to wash their hands for a sufficient period of time. This composition may be added to many different base materials to indicate time of use or as a way to introduce enjoyment to the activity.
摘要翻译：提供了颜色变化组合物，其在单一相中保持稳定，并且包含在一段时间之后产生可观察到的颜色变化的指示剂，以显示已经进行足够的清洁或指示清洁的彻底性。指示颜色变化的这种用途对于例如在肥皂中教孩子们洗手足够长时间是有用的。这种组合物可以添加到许多不同的基础材料中以指示使用时间或作为向活动引入享受的方式。

8. 发明授权

US07858568B2 Single phase color change agents 有权
标题翻译：单相变色剂
公开(公告)号：US07858568B2
公开(公告)日：2010-12-28
申请号：US12692003
申请日：2010-01-22
申请人： John Gavin MacDonald , Yanbin Huang , Kaiyuan Yang , Jaeho Kim , Ning Wei
发明人： John Gavin MacDonald , Yanbin Huang , Kaiyuan Yang , Jaeho Kim , Ning Wei
IPC分类号： A61K7/00
CPC分类号： C11D3/221 , C11D3/0042 , C11D3/40
摘要： There is provided a color change composition that remains stable in a single phase and that contains an indicator that produces an observable color change after a period of time to show that sufficient cleaning has been done or to indicate the thoroughness of the cleaning. This use indicating color change is useful for, for example, in soap for teaching children to wash their hands for a sufficient period of time. This composition may be added to many different base materials to indicate time of use or as a way to introduce enjoyment to the activity.
摘要翻译：提供了颜色变化组合物，其在单一相中保持稳定，并且包含在一段时间之后产生可观察到的颜色变化的指示剂，以显示已经进行足够的清洁或指示清洁的彻底性。指示颜色变化的这种用途对于例如在肥皂中教孩子们洗手足够长时间是有用的。这种组合物可以添加到许多不同的基础材料中以指示使用时间或作为向活动引入享受的方式。

9. 发明授权

US07851209B2 Reduction of the hook effect in assay devices 有权
标题翻译：在测定装置中减少钩效应
公开(公告)号：US07851209B2
公开(公告)日：2010-12-14
申请号：US10406631
申请日：2003-04-03
申请人： Ning Wei , Yanbin Huang , Kaiyuan Yang
发明人： Ning Wei , Yanbin Huang , Kaiyuan Yang
IPC分类号： C12M1/34
CPC分类号： G01N33/587 , G01N33/54393 , G01N33/558
摘要： A membrane-based assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes conjugated probes that contain a specific binding member for the analyte of interest. The specific binding member preferentially complexes with the analyte within a test sample when contacted therewith. Excess analyte that remains uncomplexed with the specific binding member undergoes non-specific binding, such as to a hydrophobic domain. As a result, the ability of the uncomplexed analyte to compete with the complexed analyte at the detection zone of the device is restricted. Thus, the incidence of “false negatives” is limited in a simple, efficient, and relatively inexpensive manner.
摘要翻译：提供了一种用于检测驻留在测试样品中的分析物的存在或数量的基于膜的测定装置。该装置使用包含感兴趣分析物的特异性结合成员的缀合探针。当与其接触时，特异性结合成分优先与测试样品内的分析物复合。与特异性结合成员保持未复合的过量分析物经历非特异性结合，例如疏水结构域。因此，未配合的分析物在装置的检测区域与复合分析物竞争的能力受到限制。因此，“假阴性”的发生率以简单，有效和相对便宜的方式受到限制。

10. 发明申请

US20070026074A1 Vaginal treatment composition 有权
标题翻译：阴道治疗组合物
公开(公告)号：US20070026074A1
公开(公告)日：2007-02-01
申请号：US11194064
申请日：2005-07-29
申请人： Stephanie Martin , Lei Huang , Shu-Ping Yang , Yanbin Huang , Julie Villanueva , Sharon Greene , Kelly Arehart , Curtis Sayre , Robert Johnson
发明人： Stephanie Martin , Lei Huang , Shu-Ping Yang , Yanbin Huang , Julie Villanueva , Sharon Greene , Kelly Arehart , Curtis Sayre , Robert Johnson
IPC分类号： A61K9/14 , A61K31/70 , A61K31/045
CPC分类号： A61K9/0034 , A61K31/192 , A61K31/70 , A61K47/36
摘要： A vaginal treatment composition that rapidly forms a gel when placed into contact with monovalent or polyvalent cations, such as sodium (Na+) and calcium (Ca2+) cations naturally found in vaginal mucosa, is provided. The gel may form in less than about 1 hour, in some embodiments less than about 1 minute, and in some embodiments, less than about 30 seconds. Among other things, such rapid gelation reduces the likelihood of leakage during use. In addition, because the gel may form intravaginally, it is more likely to retain its structure and shape over an extended period of time. In this manner, the gel may provide the prolonged release of a therapeutic agent that inhibits and/or treats vaginal infection. For instance, the gel may remain within the vagina for about 2 to about 48 hours to provide the desired effect.
摘要翻译：当与一价或多价阳离子接触时迅速形成凝胶的阴道处理组合物，例如天然存在的钠（Na +）+和钙（Ca 2+）+阳离子提供阴道粘膜。凝胶可以在小于约1小时，在一些实施方案中小于约1分钟，并且在一些实施方案中小于约30秒形成。除此之外，这种快速凝胶化可降低使用过程中泄漏的可能性。另外，因为凝胶可以阴道内形成，所以更可能在延长的时间段内保持其结构和形状。以这种方式，凝胶可提供抑制和/或治疗阴道感染的治疗剂的延长释放。例如，凝胶可以保留在阴道内约2至约48小时以提供期望的效果。

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