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1. 发明申请

US20120305174A1 LAYER PROCESSING FOR PHARMACEUTICALS 有权
标题翻译：药物的层加工
公开(公告)号：US20120305174A1
公开(公告)日：2012-12-06
申请号：US13458222
申请日：2012-04-27
申请人： Bernhardt Levy Trout , Trevor Alan Hatton , Emily Chang , James MB Evans , Salvatore Mascia , Won Kim , Ryan Richard Slaughter , Yi Du , Himanshu Hemant Dhamankar , Keith M. Forward , Gregory C. Rutledge , Mao Wang , Allan Stuart Myerson , Blair Kathryn Brettmann , Nikhil Padhye , Jung-Hoon Chun
发明人： Bernhardt Levy Trout , Trevor Alan Hatton , Emily Chang , James MB Evans , Salvatore Mascia , Won Kim , Ryan Richard Slaughter , Yi Du , Himanshu Hemant Dhamankar , Keith M. Forward , Gregory C. Rutledge , Mao Wang , Allan Stuart Myerson , Blair Kathryn Brettmann , Nikhil Padhye , Jung-Hoon Chun
IPC分类号： A61K9/70 , B29C59/16 , B29C39/00
CPC分类号： A61K31/55 , A61J3/00 , A61J3/06 , A61J3/10 , A61K9/2027 , A61K9/209 , A61K9/7007 , A61K31/165 , A61K31/426 , Y10T156/1051
摘要： Layer processing for pharmaceuticals, and related systems, methods, and articles are generally described. In some embodiments, ingestible pharmaceutical products (e.g., tablets) can be formed by processing one or more layers containing a pharmaceutically active composition. For example, at least one layer containing a pharmaceutically active composition can be manipulated (e.g., folded, rolled, stacked, etc.) such that the average thickness of the product formed by the manipulation is at least about two times the average thickness of the portions of the layer(s) used to form the product. In some embodiments, after the layer is manipulated, it can be processed (e.g., cut, coated, etc.) to form a final product such as, for example, a tablet.
摘要翻译：通常描述药物的层加工以及相关系统，方法和制品。在一些实施方案中，可以通过加工含有药物活性组合物的一层或多层来形成可摄取的药物产品（例如片剂）。例如，可以操作含有药物活性组合物的至少一层（例如，折叠，卷绕，堆叠等），使得通过操作形成的产品的平均厚度至少为平均厚度的两倍用于形成产品的层的部分。在一些实施方案中，在操作该层之后，可以处理（例如，切割，涂覆等）以形成最终产品，例如片剂。

2. 发明授权

US09205089B2 Layer processing for pharmaceuticals 有权
标题翻译：药物层加工
公开(公告)号：US09205089B2
公开(公告)日：2015-12-08
申请号：US13458222
申请日：2012-04-27
申请人： Bernhardt Levy Trout , Trevor Alan Hatton , Emily Chang , James M B Evans , Salvatore Mascia , Won Kim , Ryan Richard Slaughter , Yi Du , Himanshu Hemant Dhamankar , Keith M. Forward , Gregory C. Rutledge , Mao Wang , Allan Stuart Myerson , Blair Kathryn Brettmann , Nikhil Padhye , Jung-Hoon Chun
发明人： Bernhardt Levy Trout , Trevor Alan Hatton , Emily Chang , James M B Evans , Salvatore Mascia , Won Kim , Ryan Richard Slaughter , Yi Du , Himanshu Hemant Dhamankar , Keith M. Forward , Gregory C. Rutledge , Mao Wang , Allan Stuart Myerson , Blair Kathryn Brettmann , Nikhil Padhye , Jung-Hoon Chun
IPC分类号： A61K9/70 , A61K31/55 , A61K9/20 , A61K9/24 , A61K31/165 , A61K31/426 , A61J3/00 , A61J3/06 , A61J3/10
CPC分类号： A61K31/55 , A61J3/00 , A61J3/06 , A61J3/10 , A61K9/2027 , A61K9/209 , A61K9/7007 , A61K31/165 , A61K31/426 , Y10T156/1051
摘要： Layer processing for pharmaceuticals, and related systems, methods, and articles are generally described. In some embodiments, ingestible pharmaceutical products (e.g., tablets) can be formed by processing one or more layers containing a pharmaceutically active composition. For example, at least one layer containing a pharmaceutically active composition can be manipulated (e.g., folded, rolled, stacked, etc.) such that the average thickness of the product formed by the manipulation is at least about two times the average thickness of the portions of the layer(s) used to form the product. In some embodiments, after the layer is manipulated, it can be processed (e.g., cut, coated, etc.) to form a final product such as, for example, a tablet.
摘要翻译：通常描述药物的层加工以及相关系统，方法和制品。在一些实施方案中，可以通过加工含有药物活性组合物的一层或多层来形成可摄取的药物产品（例如片剂）。例如，可以操作含有药物活性组合物的至少一层（例如，折叠，卷绕，堆叠等），使得通过操作形成的产品的平均厚度至少为平均厚度的两倍用于形成产品的层的部分。在一些实施方案中，在操作该层之后，可以处理（例如，切割，涂覆等）以形成最终产品，例如片剂。

3. 发明授权

US06317200B1 Positional measurement with normalized signal processing 失效
标题翻译：采用归一化信号处理进行位置测量
公开(公告)号：US06317200B1
公开(公告)日：2001-11-13
申请号：US09548918
申请日：2000-04-13
申请人： Mao Wang , John C. Tsai
发明人： Mao Wang , John C. Tsai
IPC分类号： G01C308
CPC分类号： G01S17/10 , G01D5/26 , G01S7/4811 , G01S7/4812
摘要： A measurement apparatus (10, 110) and methods to perform positional types of measurement with normalization respective to either or both of light beam (16, 116) intensity and measurement target (12, 112) reflectivity. A light source, such as a laser diode (14, 114), produces a light beam (16, 116) which is directed at the measurement target (12, 112). One or more beamsplitters (28, 120, 124) in the path of the light beam (16, 116) direct sample portions into one or more photodetectors (32, 36, 122, 128) to obtain either or both of illumination and reflectivity sample values. A portion of the light beam (16, 116) which is reflected by the measurement target (12, 112) is passed through and restricted by an aperture (26, 132) and then detected by a position sensitive detector (38, 134) to obtain a position value. The position value may then be normalized based on either or both of the illumination and reflectivity sample values.
摘要翻译：测量装置（10,110）以及对光束（16,116）强度和测量目标（12,112）之一或两者进行归一化的位置测量类型的测量装置（10,110）反射率。诸如激光二极管（14,114）的光源产生指向测量目标（12,112）的光束（16,116）。在光束（16,116）的路径中的一个或多个分束器（28,120,124）将样本部分引导到一个或多个光电检测器（32,36,122,128）中以获得照明和反射率样本中的任一个或两者价值观。由测量对象（12,112）反射的光束（16,116）的一部分被孔径（26,132）通过并被一个位置敏感检测器（38,134）检测到获得位置值。然后可以基于照明和反射率样本值中的一个或两者来归一化位置值。

4. 发明申请

US20060019096A1 Field-responsive superparamagnetic composite nanofibers and methods of use thereof 审中-公开
标题翻译：场响应超顺磁复合纳米纤维及其使用方法
公开(公告)号：US20060019096A1
公开(公告)日：2006-01-26
申请号：US11141205
申请日：2005-06-01
申请人： T. Hatton , Gregory Rutledge , Harpreet Singh , Mao Wang
发明人： T. Hatton , Gregory Rutledge , Harpreet Singh , Mao Wang
IPC分类号： D02G3/00
CPC分类号： D01D5/0038 , D01D5/0007 , D01F1/10 , D01F6/14 , D01F6/16 , Y10T428/2913
摘要： The present invention relates to magnetic field-responsive fibers, which comprise magnetite particles and a polymeric matrix. The invention also provides methods of producing the same, in particular via electrospinning of a stably dispersed or monodispersed polymer solution, either aqueous or organic, comprising the magnetite particles, and applications thereof.
摘要翻译：本发明涉及包含磁铁矿颗粒和聚合物基体的磁场响应纤维。本发明还提供了制备该方法的方法，特别是通过静电纺丝稳定分散或单分散的包含磁铁矿颗粒的水性或有机聚合物溶液及其应用。

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