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1. 发明申请

US20080176811A1 NOVEL FLAVONE GLYCOSIDE DERIVATIVES FOR USE IN COSMETICS, PHARMACEUTICALS AND NUTRITION 审中-公开
标题翻译：用于化妆品，药物和营养物质的新型FLAVONE GLYCONE衍生物
公开(公告)号：US20080176811A1
公开(公告)日：2008-07-24
申请号：US12057425
申请日：2008-03-28
申请人： Bernadette Geers , Ralf Otto , Albrecht Weiss , Dirk Petersohn , Klaus Rudolf Schroeder , Kordula Schlotmann
发明人： Bernadette Geers , Ralf Otto , Albrecht Weiss , Dirk Petersohn , Klaus Rudolf Schroeder , Kordula Schlotmann
IPC分类号： A61K31/7048 , C07H17/06 , C12P19/60 , A61P17/00 , A61Q19/02
CPC分类号： A61K8/602 , A23L33/105 , A23V2002/00 , A61K8/73 , A61Q19/02 , C07H17/07 , C12P7/62 , C12P17/06 , C12P19/60 , A23V2250/2116 , A23V2250/1866
摘要： Substituted and unsubstituted flavone or isoflavone glycoside derivatives of the formula [A1-C(═O)O]m—[X—O-Z]—[O—C(═O)-A2]n, wherein [X—O-Z] represents a flavone or isoflavone glycoside structure, particularly a naringin residue, X is a flavone or isoflavone corresponding to formula (IIa) or formula (IIb): wherein the flavone or isoflavone residue is substituted one or more times and/or reduced one or more times; Z represents a mono-, di- or polysaccharide, which is acetally-bound at the benzopyran group to X and ester-substituted by —O—C(═O)-A2; [A1-C(═O)] is an acyl group on the flavone or isoflavone; A1 and A2 independently, represent a polyunsaturated C15-26 alkenyl group containing at least four isolated and/or at least two conjugated double bonds, or an arylaliphatic radical with 1-to-4 methylene groups between the ester group and the aromatic ring; [C(═O)A2] is an acyl group; n is an integer other than 0; m is an integer, including 0; and R1, R2 and R are hydroxyl groups or hydrogen atoms.
摘要翻译：取代和未取代的式[A-1-C（-O）O] - [XOZ] - [OC（-O）-A）的黄酮或异黄酮糖苷衍生物其中[XOZ]表示黄酮或异黄酮糖苷结构，特别是柚皮苷残基，X是与式（IIa）或式（IIa）相应的黄酮或异黄酮 IIb）：其中所述黄酮或异黄酮残基被一次或多次取代和/或还原一次或多次; Z表示一种，二或多糖，其在苯并吡喃基团处与X缩合而X和被-O-C（-O）-A 2 - 被酯取代。 [A-1] -C（-O）]是黄酮或异黄酮上的酰基; A 1和A 2独立地表示含有至少四个分离和/或至少两个共轭双键的多不饱和C 15-26亚烯基或在酯基和芳香环之间具有1至4个亚甲基的芳基脂族基; [C（-O）A 2]是酰基; n是0以外的整数; m是整数，包括0; 并且R 1，R 2和R 2是羟基或氢原子。

2. 发明申请

US20060057689A1 Method for producing c4-c12 fatty acids 审中-公开
标题翻译：生产c4-c12脂肪酸的方法
公开(公告)号：US20060057689A1
公开(公告)日：2006-03-16
申请号：US10513812
申请日：2003-04-29
申请人： Ralf Otto , Georg Fieg , Sabine Both , Ulrich Schoerken , Levent Yueksel , Ingomar Mrozek , Carolin Meyer , Norbert Klein , Albrecht Weiss
发明人： Ralf Otto , Georg Fieg , Sabine Both , Ulrich Schoerken , Levent Yueksel , Ingomar Mrozek , Carolin Meyer , Norbert Klein , Albrecht Weiss
IPC分类号： C12P7/64 , C12P7/40
CPC分类号： C12P7/6418 , C12P7/40
摘要： Processes for preparing fatty acids are described wherein a C4-C12 fatty acid methyl ester is subjected to hydrolysis in the presence of an enzyme to form an organic phase comprising a C4-C12 fatty acid and an aqueous phase comprising methanol, wherein at least a portion of the methanol is continuously removed; and the organic phase is subsequently separated from the aqueous phase, and optionally, where the organic phase further comprises an unhydrolyzed portion of the C4-C12 fatty acid methyl ester, the unhydrolyzed portion of the C4-C12 fatty acid methyl ester is separated from the C4-C12 fatty acid.
摘要翻译：描述了制备脂肪酸的方法，其中在酶的存在下使C 4 -C 12脂肪酸甲酯进行水解以形成包含C 脂肪酸和包含甲醇的水相，其中至少部分甲醇被连续除去; 随后将有机相与水相分离，任选地，当有机相进一步包含C 6-14脂肪酸甲酯的未水解部分时，将C 4 -C 12脂肪酸甲酯的未水解部分与C 4 -C 12脂肪酸甲酯分离 >脂肪酸。

3. 发明授权

US06750332B1 Salicyl alcohol derivatives 失效
标题翻译：水杨醇衍生物
公开(公告)号：US06750332B1
公开(公告)日：2004-06-15
申请号：US09856835
申请日：2002-02-26
申请人： Ralf Otto , Albrecht Weiss
发明人： Ralf Otto , Albrecht Weiss
IPC分类号： C07H1500
CPC分类号： C07H15/04 , A61K8/602 , A61Q19/00 , C08B37/00 , C12P7/62 , C12P19/44
摘要： Novel salicyl alcohol derivatives having valuable cosmetically and pharmaceutically useful properties, such as prostaglandin synthesis inhibition, corresponding to the formula (I): R1—OCH2—Ph—O—Z—(R2)n (I), a method for producing the same and their utilization in cosmetics and pharmacy.
摘要翻译：新颖的水杨醇衍生物具有有价值的美容和药学上有用的性质，如前列腺素合成抑制，对应于式（I）：其制备方法及其在化妆品和药学中的应用。

4. 发明授权

US06897328B2 Process for deacidifying natural fats and oils 有权
标题翻译：脱酸天然油脂的方法
公开(公告)号：US06897328B2
公开(公告)日：2005-05-24
申请号：US10301333
申请日：2002-11-21
申请人： Bernhard Gutsche , Albrecht Weiss , Ralf Otto , Tycho Michel
发明人： Bernhard Gutsche , Albrecht Weiss , Ralf Otto , Tycho Michel
IPC分类号： C11B3/00 , C11C3/00 , C07C51/43
CPC分类号： C11C3/003 , C11B3/003
摘要： A single stage process for deacidifying glycerides involving: (a) providing a glyceride having an acid value of from about 5 to 20; (b) providing a lower alcohol; (c) providing an enzyme catalyst immobilized on a support material; and passing a mixture of (a) and (b), over (c), thereby deacidifying the glycerides.
摘要翻译：用于脱酸甘油酯的单阶段方法，涉及：（a）提供酸值为约5至20的甘油酯; （b）提供低级醇; （c）提供固定在载体材料上的酶催化剂; 并通过（a）和（b）的混合物，超过（c），从而使甘油酯脱酸。

5. 发明申请

US20130027770A1 Microscope Illumination Method and Microscope 有权
标题翻译：显微镜照明方法和显微镜
公开(公告)号：US20130027770A1
公开(公告)日：2013-01-31
申请号：US13559778
申请日：2012-07-27
申请人： Michael Ganser , Albrecht Weiss
发明人： Michael Ganser , Albrecht Weiss
IPC分类号： G02B21/06
CPC分类号： G02B21/088 , G02B5/22 , G02B21/125 , G02B21/16
摘要： The invention relates to a microscope illumination method, to a microscope illumination set, comprising a white light LED (4) and a correction filter (6), and to a corresponding microscope system (1) for analysing a sample (10) alternately or simultaneously in transmitted light bright field illumination and in incident light fluorescence illumination, wherein a white light LED (4) is used for the transmitted light bright field illumination, and a correction filter (6) is activated at a location in the illumination beam path of the transmitted light bright field illumination both during transmitted light bright field illumination and during incident light fluorescence illumination, wherein the correction filter (6) has a spectral transmission profile which has a minimum in the wavelength range of at least one maximum of the spectrum of the white light LED (4).
摘要翻译：本发明涉及一种显微照明方法，涉及一种包括白光LED（4）和校正滤光片（6）的显微照明组件，以及用于交替或同时分析样品（10）的相应显微系统（1）在透射光明场照明和入射光荧光照明中，其中白光LED（4）用于透射光明场照明，校正滤光片（6）在照明光束路径中的位置被激活在透射光明场照明期间和在入射光荧光照明期间的透射光明场照明，其中所述校正滤光片（6）具有光谱透射分布，所述光谱透射分布在白色光谱的至少一个最大值的波长范围内具有最小值灯LED（4）。

6. 发明申请

US20120201776A1 Hair Relaxer 有权
标题翻译：头发放松
公开(公告)号：US20120201776A1
公开(公告)日：2012-08-09
申请号：US13379788
申请日：2010-06-17
申请人： Hans-Martin Haake , Ralf Bohlander , Jessica Cecchini , Mehmet Yücel Altunok , Albrecht Weiss , Angela Brands
发明人： Hans-Martin Haake , Ralf Bohlander , Jessica Cecchini , Mehmet Yücel Altunok , Albrecht Weiss , Angela Brands
IPC分类号： A61K8/25 , A61Q5/04 , A61K8/73
CPC分类号： A61K8/25 , A61K8/062 , A61K8/19 , A61K8/345 , A61K8/43 , A61K8/604 , A61Q5/04
摘要： The invention relates to a hair smoothing agent characterized by a content of sodium silicate.
摘要翻译：本发明涉及以硅酸钠的含量为特征的毛发光滑剂。

7. 发明申请

US20100234458A1 Process for the Production of Fatty Acid Alkyl Esters 失效
标题翻译：脂肪酸烷基酯的制备方法
公开(公告)号：US20100234458A1
公开(公告)日：2010-09-16
申请号：US12304078
申请日：2007-05-16
申请人： Eric Dubreucq , Albrecht Weiss , Bernhard Gutsche , Bernd Fabry , Guy Moulin
发明人： Eric Dubreucq , Albrecht Weiss , Bernhard Gutsche , Bernd Fabry , Guy Moulin
IPC分类号： A61K8/37 , C12P7/64 , A61Q90/00 , A23L1/28 , A23D9/00
CPC分类号： C12P7/649 , A23K10/10 , C10L1/026 , C11C3/003 , Y02E50/13 , Y02E50/17
摘要： Disclosed is an improved process for the production of fatty acid lower alkyl esters according to formula (I) R1CO—OR2 (I) in which R1CO represents a linear or branched acyl moiety having from about 6 to about_22 carbon atoms and 0 to 6 double bonds and wherein R2 is a linear or branched alkyl moiety having 1 to 6 carbon atoms, by transesterification of triglycerides or fatty acid esters using C1-C6 aliphatic alcohols, which includes the steps of (a) providing an aqueous mixture of aliphatic C1-C6 alcohol by fermenting in a first reactor a carbon_source comprising carbohydrates and/or glycerol produce a fermentation broth comprising said aliphatic C1-C6 alcohol, (b) providing in a second reactor a triglyceride and/or an ester of a fatty acid, together with a biocatalyst capable of effecting a transesterification reaction, (c) transferring said aqueous aliphatic C1-C6 alcohol mixture obtained from said first reactor into said_second reactor to provide_a two-phase system, and (d) effecting the transesterification reaction to produce said fatty acid lower alkyl ester and a glycerol- or alcohol-containing aqueous phase. The products thus obtained are particularly useful as components of the fuel known as biodiesel.
摘要翻译：公开了一种改进的根据式（I）R1CO-OR2（I）的脂肪酸低级烷基酯的制备方法，其中R 1 CO表示具有约6至约22个碳原子和0至6个双键的直链或支链酰基部分并且其中R 2是具有1至6个碳原子的直链或支链烷基部分，通过使用C 1 -C 6脂族醇进行甘油三酯或脂肪酸酯的酯交换反应，其包括以下步骤：（a）提供脂族C1-C6醇的水性混合物通过在第一反应器中发酵包含碳水化合物和/或甘油的碳源产生包含所述脂族C 1 -C 6醇的发酵液，（b）在第二反应器中提供甘油三酯和/或脂肪酸酯以及生物催化剂能够进行酯交换反应，（c）将从所述第一反应器获得的脂族C1-C6醇混合物混合物转移到所述第二反应器中以提供两相体系，和（d）进行酯交换反应以产生所述脂肪酸低级烷基酯和含甘油或醇的水相。这样得到的产物特别适用于称为生物柴油的燃料的组分。

8. 发明申请

US20080198448A1 FLUORESCENCE MICROSCOPE HAVING AN ILLUMINATION DEVICE 有权
标题翻译：具有照明装置的荧光显微镜
公开(公告)号：US20080198448A1
公开(公告)日：2008-08-21
申请号：US12032435
申请日：2008-02-15
申请人： Michael Ganser , Albrecht Weiss
发明人： Michael Ganser , Albrecht Weiss
IPC分类号： G02B21/06
CPC分类号： G02B21/16 , G02B21/06 , G02B27/1006
摘要： An arrangement for fluorescence microscopic examination of specimens includes: a fluorescence microscope; an illumination device that includes: a housing including an interface configured to optically couple the housing and the fluorescence microscope; a plurality of light-emitting diodes disposed in the housing; a respective collector disposed downstream of each of the light emitting diodes and configured to generate a directed light flux; and at least one dichroic splitter disposed in the housing, the at least one splitter and the light-emitting diodes being spatially disposed with respect to one another so that the directed light fluxes are combinable via the at least one splitter into a common illumination beam path directed onto the interface; and a logical control device common to the fluorescence microscope and the illumination device.
摘要翻译：用于荧光显微镜检查的样品的布置包括：荧光显微镜; 一种照明装置，包括：壳体，包括被配置为光耦合所述壳体和所述荧光显微镜的接口; 设置在所述壳体中的多个发光二极管; 设置在每个所述发光二极管的下游并且被配置为产生有向光通量的相应集电极; 以及设置在所述壳体中的至少一个二向色分配器，所述至少一个分离器和所述发光二极管相对于彼此在空间上设置，使得所述定向光束可经由所述至少一个分离器组合成公共照明光束路径指向界面; 以及荧光显微镜和照明装置通用的逻辑控制装置。

9. 发明申请

US20070190595A1 Process for obtaining zeaxanthin from algae 审中-公开
标题翻译：从藻类中获得玉米黄质的方法
公开(公告)号：US20070190595A1
公开(公告)日：2007-08-16
申请号：US11650264
申请日：2007-01-05
申请人： Albrecht Weiss , Wilhelm Johannisbauer , Bernhard Gutsche , Baldomero Cordero , Lucia Martin , Herminia Rodriguez , M. Angeles Vargas , Irina Obraztsova
发明人： Albrecht Weiss , Wilhelm Johannisbauer , Bernhard Gutsche , Baldomero Cordero , Lucia Martin , Herminia Rodriguez , M. Angeles Vargas , Irina Obraztsova
IPC分类号： C12P1/00
CPC分类号： C12P23/00
摘要： A process of obtaining zeaxanthin in a high yield from blue-green algae is de-scribed. Zeaxanthin and zeaxanthin-enriched products obtained by the process, which are suitable for use as dietary supplements and/or food additives, are also described.
摘要翻译：描述了从蓝绿色藻类获得高产量的玉米黄质的方法。还描述了通过该方法获得的适合用作膳食补充剂和/或食品添加剂的玉米黄质和富含玉米黄质的产品。

10. 发明授权

US07247463B2 Enzymes with lipase/acyltransferase activity, nucleic acids encoding the same and methods of use thereof 有权
标题翻译：具有脂肪酶/酰基转移酶活性的酶，编码其的核酸及其使用方法
公开(公告)号：US07247463B2
公开(公告)日：2007-07-24
申请号：US10681636
申请日：2003-10-08
申请人： Albrecht Weiss , Frederic Bigey , Eric Dubreucq , Guy Moulin
发明人： Albrecht Weiss , Frederic Bigey , Eric Dubreucq , Guy Moulin
IPC分类号： C12N9/10 , C12N9/20
CPC分类号： C12N9/1025 , C12N9/20
摘要： Polypeptides with lipase/acyltransferase activity are described with an amino acid sequence which has identity to the sequence reported in SEQ ID NO 2 of at least 49%, also polypeptides which display this activity, as well as nucleic acids (genes) which code for these polypeptides, vectors which contain nucleic acids which code for these polypeptides, transformed microorganisms which contain these nucleic acids, processes for production of these polypeptides and the application of nucleic acids for discovering new lipase/acyltransferases and the use of these lipase/acyltransferases as catalysts in chemical and biochemical processes.
摘要翻译：具有脂肪酶/酰基转移酶活性的多肽用与SEQ ID NO 2中报道的序列具有至少49％的同一性的氨基酸序列以及显示该活性的多肽以及编码这些活性的核酸（基因）来描述多肽，含有编码这些多肽的核酸的载体，含有这些核酸的转化微生物，这些多肽的生产方法和用于发现新的脂肪酶/酰基转移酶的核酸的应用以及这些脂肪酶/酰基转移酶作为催化剂的用途化学和生化过程。

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