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1. 发明授权

US07803604B2 Amylolytic enzyme extracted from Bacillus sp. A 7-7 (DSM 12368) and washing and cleaning agents containing this novel amylolytic enzyme 有权
标题翻译：从芽孢杆菌提取的淀粉分解酶 A 7-7（DSM 12368）和含有该新型淀粉分解酶的洗涤和清洁剂
公开(公告)号：US07803604B2
公开(公告)日：2010-09-28
申请号：US11975898
申请日：2007-10-22
申请人： Roland Breves , Karl-Heinz Maurer , Beatrix Kottwitz , Laura Polanyi-Bald , Angela Hellebrandt , Irmgard Schmidt , Regina Stehr , Angrit Weber
发明人： Roland Breves , Karl-Heinz Maurer , Beatrix Kottwitz , Laura Polanyi-Bald , Angela Hellebrandt , Irmgard Schmidt , Regina Stehr , Angrit Weber
IPC分类号： C12N1/20
CPC分类号： C12N9/2417 , C11D3/386 , Y02E50/17 , Y10T156/10 , Y10T156/1111
摘要： The invention relates to a novel amylolytic enzyme extracted from the microorganism Bacillus sp. A 7-7 (DSM 12368), to sufficiently similar proteins having an amylolytic function, to methods for the production thereof and to diverse fields of application for these proteins. In addition, the aforesaid can be further developed beyond the implemented fields of application for other technical purposes. The invention particularly relates to washing and cleaning agents containing amylolytic proteins of the aforementioned type, to methods for cleaning textiles or hard surfaces that involve the use of the amylolytic proteins or analogous agents, and to their use for cleaning textiles or hard surfaces.
摘要翻译：本发明涉及一种从微生物芽孢杆菌中提取的新型淀粉分解酶。 A7-7（DSM12368），具有具有淀粉分解功能的足够相似的蛋白质，其制备方法以及这些蛋白质的应用领域。此外，上述可以进一步开发超出其他技术目的的实施应用领域。本发明特别涉及含有上述类型的淀粉分解蛋白质的洗涤和清洁剂，涉及使用淀粉分解蛋白质或类似剂的纺织品或硬质表面的清洁方法及其用于清洁纺织品或硬质表面的用途。

2. 发明申请

US20050049165A1 Detergent and cleaning agent with hybrid alpha-amylases 审中-公开
标题翻译：具有混合α-淀粉酶的洗涤剂和清洁剂
公开(公告)号：US20050049165A1
公开(公告)日：2005-03-03
申请号：US10774018
申请日：2004-02-06
申请人： Beatrix Kottwitz , Roland Breves , Karl-Heinz Maurer
发明人： Beatrix Kottwitz , Roland Breves , Karl-Heinz Maurer
IPC分类号： C11D3/386 , C12N9/28
CPC分类号： C12N9/2417 , C07K2319/00 , C11D3/38609 , C12Y302/01001
摘要： The present invention relates compositions and methods involving hybrid α-amylases derived from the α-amylases of the bacteria species Bacillus amyloliquefaciens and Bacillus licheniformis. In one embodiment, the hybrid α-amylases are used in detergents and cleaning agents.
摘要翻译：本发明涉及包含衍生自细菌种解淀粉芽孢杆菌和地衣芽孢杆菌的α-淀粉酶的杂合α-淀粉酶的组合物和方法。在一个实施方案中，混合的α-淀粉酶用于洗涤剂和清洁剂中。

3. 发明申请

US20050026269A1 Novel alkaline protease variants and detergents and cleaning agents containing said novel alkaline protease variants 审中-公开
标题翻译：含有所述新型碱性蛋白酶变体的新型碱性蛋白酶变体和洗涤剂和清洁剂
公开(公告)号：US20050026269A1
公开(公告)日：2005-02-03
申请号：US10476463
申请日：2002-04-24
申请人： Beatrix Kottwitz , Karl-Heinz Maurer , Roland Breves
发明人： Beatrix Kottwitz , Karl-Heinz Maurer , Roland Breves
IPC分类号： A23K1/165 , A23C19/032 , A23L1/00 , A61K8/00 , A61K8/64 , A61K8/66 , A61K8/96 , A61Q5/02 , A61Q19/10 , C11D3/386 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/54 , C12N15/09 , C12N15/31 , C12N15/57 , C12P21/06 , C12R1/07 , C12S7/00 , C12S9/00 , C12S11/00 , G03C11/24 , C07H21/04 , C12N9/56 , C12N15/74
CPC分类号： C12N9/54
摘要： Described herein are novel alkaline protease variants derived from subtilisin. These variants have, with respect to the amino acid sequence of Bacillus lentus subtilisin, variations at amino acid positions 199 and 211, and at least one modification that contributes to the stabilization of the molecule, the modification preferably being variations at amino acid positions 3 and/or 4. Preferably, the variant is B. lentus alkaline protease S3T/NV4I/V199I/L211G. Also described are detergents and cleaning agents comprising the novel alkaline protease variants. Methods of use employing the novel alkaline protease variants are also described.
摘要翻译：本文描述了衍生自枯草杆菌蛋白酶的新型碱性蛋白酶变体。这些变体具有关于迟缓芽孢杆菌枯草杆菌蛋白酶的氨基酸序列，氨基酸位置199和211的变化以及有助于分子稳定化的至少一种修饰，优选在氨基酸位置3和/ /或4.优选地，变体是枯草芽孢杆菌碱性蛋白酶S3T / NV4I / V199I / L211G。还描述了包含新型碱性蛋白酶变体的洗涤剂和清洁剂。还描述了使用新型碱性蛋白酶变体的使用方法。

4. 发明授权

US07888104B2 Cyclodextrin glucanotransferase (CGTase), obtained fromBacillus agaradherens<λ>(DSM 9948) and detergents and cleaning agents containing said novel cyclodextrin glucanotransferase 有权

标题翻译：从琼脂糖琼脂糖酸钠（DSM 9948）获得的环糊精葡聚糖转移酶（CGTase）和含有所述新型环糊精葡聚糖转移酶的洗涤剂和清洁剂

公开(公告)号：US07888104B2

公开(公告)日：2011-02-15

申请号：US10433014

申请日：2001-11-17

申请人： Beatrix Kottwitz , Karl-Heinz Maurer , Roland Breves , Irmgard Schmidt , Angrit Weber , Angela Hellebrandt , Laura Polanyi-Bald

发明人： Beatrix Kottwitz , Karl-Heinz Maurer , Roland Breves , Irmgard Schmidt , Angrit Weber , Angela Hellebrandt , Laura Polanyi-Bald

IPC分类号： C11D7/42 , C11D3/37 , C12N9/10 , C12S11/00 , C12S9/00

CPC分类号： C12N9/2417 , A23K20/189 , A23L33/17 , A61K8/66 , A61Q19/10 , C11D3/386 , C12N9/1074 , D21H25/18

摘要： The invention relates to a novel enzyme obtained from Bacillus agaradherens (DSM 9948), which can be regarded as cyclodextrin glucanotransferase (CGTase) and also as α-amylase. The invention also relates to sufficiently similar proteins or derivatives that exhibit amylolytic and/or CGTase activity, to the corresponding nucleic acids and micro-organisms that produce said proteins and derivatives, to methods for the production of said proteins and to diverse uses of the same. In addition, said proteins can be further developed for other, predominantly technical purposes. The invention relates in particular to detergents and cleaning agents containing CGTase of this type, to methods for cleaning textiles or hard surfaces using CGTase of this type or corresponding agents and to the use thereof for cleaning textiles or hard surfaces.

摘要翻译：本发明涉及从琼脂糖琼脂（DSM 9948）获得的新型酶，其可以被认为是环糊精葡聚糖转移酶（CGTase），也称为α-淀粉酶。本发明还涉及对产生所述蛋白质和衍生物的相应核酸和微生物产生淀粉分解和/或CGT酶活性的足够相似的蛋白质或衍生物，用于生产所述蛋白质的方法及其各种用途。此外，所述蛋白质可以进一步开发用于其它主要技术目的。本发明特别涉及含有这种类型的CGTase的洗涤剂和清洁剂，使用这种类型的CGTase或相应的试剂清洁纺织品或硬表面的方法以及用于清洁纺织品或硬表面的用途。

5. 发明授权

US07303905B2 Amylolytic enzyme extracted from Bacillus sp. A 7-7 (DSM 12368) and washing and cleaning agents containing this novel amylolytic enzyme 有权
标题翻译：从芽孢杆菌提取的淀粉分解酶 A 7-7（DSM 12368）和含有该新型淀粉分解酶的洗涤和清洁剂
公开(公告)号：US07303905B2
公开(公告)日：2007-12-04
申请号：US11590976
申请日：2006-11-01
申请人： Roland Breves , Karl-Heinz Maurer , Beatrix Kottwitz , Laura Polanyi-Bald , Angela Hellebrandt , Irmgard Schmidt , Regina Stehr , Angrit Weber
发明人： Roland Breves , Karl-Heinz Maurer , Beatrix Kottwitz , Laura Polanyi-Bald , Angela Hellebrandt , Irmgard Schmidt , Regina Stehr , Angrit Weber
IPC分类号： C12N9/32 , C07H21/04
CPC分类号： C12N9/2417 , C11D3/386 , Y02E50/17 , Y10T156/10 , Y10T156/1111
摘要： The invention relates to a novel amylolytic enzyme extracted from the microorganism Bacillus sp. A 7-7 (DSM 12368), to sufficiently similar proteins having an amylolytic function, to methods for the production thereof and to diverse fields of application for these proteins. In addition, they can be further developed beyond the implemented fields of application for other, above all, technical purposes. The invention particularly relates to washing and cleaning agents containing amylolytic proteins of the aforementioned type, to methods for cleaning textiles or hard surfaces that involve the use of such amylolytic proteins or analogous agents, and to their use for cleaning textiles or hard surfaces.
摘要翻译：本发明涉及一种从微生物芽孢杆菌中提取的新型淀粉分解酶。 A7-7（DSM12368），具有具有淀粉分解功能的足够相似的蛋白质，其制备方法以及这些蛋白质的应用领域。此外，它们可以进一步开发超出实施的其他领域，尤其是技术目的。本发明特别涉及含有上述类型的淀粉分解蛋白质的洗涤和清洁剂，涉及使用这种淀粉分解蛋白质或类似剂的纺织品或硬质表面的清洁方法及其用于清洁纺织品或硬表面的用途。

6. 发明申请

US20070048839A1 Novel amylolytic enzyme extracted from bacillus sp. A 7-7 (DSM 12368) and washing and cleaning agents containing this novel amylolytic enzyme 有权
标题翻译：从芽孢杆菌提取的新型淀粉分解酶 A 7-7（DSM 12368）和含有该新型淀粉分解酶的洗涤和清洁剂
公开(公告)号：US20070048839A1
公开(公告)日：2007-03-01
申请号：US11590976
申请日：2006-11-01
申请人： Roland Breves , Karl-Heinz Maurer , Beatrix Kottwitz , Laura Polanyi-Bald , Angela Hellebrandt , Irmgard Schmidt , Regina Stehr , Angrit Weber
发明人： Roland Breves , Karl-Heinz Maurer , Beatrix Kottwitz , Laura Polanyi-Bald , Angela Hellebrandt , Irmgard Schmidt , Regina Stehr , Angrit Weber
IPC分类号： C11D3/386 , C12N9/32 , C12P21/06 , C07H21/04 , C12N15/74 , C12N1/21
CPC分类号： C12N9/2417 , C11D3/386 , Y02E50/17 , Y10T156/10 , Y10T156/1111
摘要： The invention relates to a novel amylolytic enzyme extracted from the micro-organism Bacillus sp. A 7-7 (DSM 12368), to sufficiently similar proteins having an amylolytic function, to methods for the production thereof and to diverse fields of application for these proteins. In addition, they can be further developed beyond the implemented fields of application for other, above all, technical purposes. The invention particularly relates to washing and cleaning agents containing amylolytic proteins of the aforementioned type, to methods for cleaning textiles or hard surfaces that involve the use of such amylolytic proteins or analogous agents, and to their use for cleaning textiles or hard surfaces.
摘要翻译：本发明涉及从微生物芽孢杆菌属（Bacillus sp。）提取的新型淀粉分解酶。 A7-7（DSM12368），具有具有淀粉分解功能的足够相似的蛋白质，其制备方法以及这些蛋白质的应用领域。此外，它们可以进一步开发超出实施的其他领域，尤其是技术目的。本发明特别涉及含有上述类型的淀粉分解蛋白质的洗涤和清洁剂，涉及使用这种淀粉分解蛋白质或类似剂的纺织品或硬质表面的清洁方法及其用于清洁纺织品或硬表面的用途。

7. 发明授权

US07153818B2 Amylolytic enzyme extracted from bacillus sp. A 7-7 (DSM 12368) and washing and cleaning agents containing this novel amylolytic enzyme 有权
标题翻译：从芽孢杆菌提取的淀粉分解酶 A 7-7（DSM 12368）和含有该新型淀粉分解酶的洗涤和清洁剂
公开(公告)号：US07153818B2
公开(公告)日：2006-12-26
申请号：US10343212
申请日：2001-07-19
申请人： Roland Breves , Karl-Heinz Maurer , Beatrix Kottwitz , Laura Polanyi-Bald , Angela Hellebrandt , Irmgard Schmidt , Regina Stehr , Angrit Weber
发明人： Roland Breves , Karl-Heinz Maurer , Beatrix Kottwitz , Laura Polanyi-Bald , Angela Hellebrandt , Irmgard Schmidt , Regina Stehr , Angrit Weber
IPC分类号： C12N9/26
CPC分类号： C12N9/2417 , C11D3/386 , Y02E50/17 , Y10T156/10 , Y10T156/1111
摘要： The invention relates to a novel amylolytic enzyme extracted from the micro-organism Bacillus sp. A7-7 (DSM 12368), to sufficiently similar proteins having an amylolytic function, to methods for the production thereof and to diverse fields of application for these proteins. In addition, they can be further developed beyond the implemented fields of application for other, above all, technical purposes. The invention particularly relates to washing and cleaning agents containing amylolytic proteins of the aforementioned type, to methods for cleaning textiles or hard surfaces that involve the use of such amylolytic proteins or analogous agents, and to their use for cleaning textiles or hard surfaces.
摘要翻译：本发明涉及从微生物芽孢杆菌属（Bacillus sp。）提取的新型淀粉分解酶。 A7-7（DSM12368），具有具有淀粉分解功能的足够相似的蛋白质，其生产方法和这些蛋白质的各种应用领域。此外，它们可以进一步开发超出实施的其他领域，尤其是技术目的。本发明特别涉及含有上述类型的淀粉分解蛋白质的洗涤和清洁剂，涉及使用这种淀粉分解蛋白质或类似剂的纺织品或硬质表面的清洁方法及其用于清洁纺织品或硬表面的用途。

8. 发明申请

US20090120555A1 Novel amylolytic enzyme extracted from Bacillus sp. A 7-7 (DSM 12368) and washing and cleaning agents containing this novel amylolytic enzyme 有权
标题翻译：从芽孢杆菌提取的新型淀粉分解酶 A 7-7（DSM 12368）和含有该新型淀粉分解酶的洗涤和清洁剂
公开(公告)号：US20090120555A1
公开(公告)日：2009-05-14
申请号：US11975898
申请日：2007-10-22
申请人： Roland Breves , Karl-Heinz Maurer , Beatrix Kottwitz , Laura Polanyi-Bald , Angela Hellebrandt , Irmgard Schmidt , Regina Stehr , Angrit Weber
发明人： Roland Breves , Karl-Heinz Maurer , Beatrix Kottwitz , Laura Polanyi-Bald , Angela Hellebrandt , Irmgard Schmidt , Regina Stehr , Angrit Weber
IPC分类号： B29C65/00 , C12N1/20 , C12P1/00
CPC分类号： C12N9/2417 , C11D3/386 , Y02E50/17 , Y10T156/10 , Y10T156/1111
摘要： The invention relates to a novel amylolytic enzyme extracted from the microorganism Bacillus sp. A 7-7 (DSM 12368), to sufficiently similar proteins having an amylolytic function, to methods for the production thereof and to diverse fields of application for these proteins. In addition, the aforesaid can be further developed beyond the implemented fields of application for other technical purposes. The invention particularly relates to washing and cleaning agents containing amylolytic proteins of the aforementioned type, to methods for cleaning textiles or hard surfaces that involve the use of the amylolytic proteins or analogous agents, and to their use for cleaning textiles or hard surfaces.
摘要翻译：本发明涉及一种从微生物芽孢杆菌中提取的新型淀粉分解酶。 A7-7（DSM12368），具有具有淀粉分解功能的足够相似的蛋白质，其制备方法以及这些蛋白质的应用领域。此外，上述可以进一步开发超出其他技术目的的实施应用领域。本发明特别涉及含有上述类型的淀粉分解蛋白质的洗涤和清洁剂，涉及使用淀粉分解蛋白质或类似剂的纺织品或硬质表面的清洁方法及其用于清洁纺织品或硬质表面的用途。

9. 发明授权

US07320887B2 Alkaline protease variants 失效
标题翻译：碱性蛋白酶变体
公开(公告)号：US07320887B2
公开(公告)日：2008-01-22
申请号：US10836959
申请日：2004-04-30
申请人： Beatrix Kottwitz , Karl-Heinz Maurer , Roland Breves
发明人： Beatrix Kottwitz , Karl-Heinz Maurer , Roland Breves
IPC分类号： C12N9/54 , C12N15/57 , C12N15/74 , C11D3/386
CPC分类号： C12N9/54 , C11D3/38681
摘要： The invention relates to novel alkaline protease variants. These variants have, when enumerating the alkaline protease from Bacillus lentus, variations in amino acid position 61, positions 199 and/or 211 and, optionally, at least one modification that contributes to the stabilization of the molecule, said modification preferably being point mutations in positions 3 and/or 4. Particularly preferred are variants S3T/V41/G61A/V199] and S3T/V41/G61A/V1991/L211D of B. lentus alkaline protease. The invention also relates to the possible use of these enzymes in diverse technical processes and, in particular, to detergents and cleansers containing these novel alkaline protease variants.
摘要翻译：本发明涉及新的碱性蛋白酶变体。当列举来自迟缓芽孢杆菌的碱性蛋白酶时，这些变体具有氨基酸位置61，位置199和/或211的变化，和任选地至少一个有助于分子稳定化的修饰，所述修饰优选是点突变位置3和/或4.特别优选的是变形芽孢杆菌碱性蛋白酶的变体S3T / V41 / G61A / V199]和S3T / V41 / G61A / V1991 / L211D。本发明还涉及这些酶在不同技术过程中的可能用途，特别涉及含有这些新型碱性蛋白酶变体的洗涤剂和清洁剂。

10. 发明申请

US20050003985A1 Alkaline protease variants 失效
标题翻译：碱性蛋白酶变体
公开(公告)号：US20050003985A1
公开(公告)日：2005-01-06
申请号：US10836959
申请日：2004-04-30
申请人： Beatrix Kottwitz , Karl-Heinz Maurer , Roland Breves
发明人： Beatrix Kottwitz , Karl-Heinz Maurer , Roland Breves
IPC分类号： A23K1/165 , A23C19/032 , A23L1/00 , A61K8/00 , A61K8/66 , A61K8/72 , A61Q19/10 , C11D3/386 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/54 , C12N15/09 , C12N15/57 , C12P21/06 , C12Q1/37 , C14C11/00 , D06L4/40 , D06M16/00 , D06M101/12 , C07H21/04 , C12N15/74
CPC分类号： C12N9/54 , C11D3/38681
摘要： The invention relates to novel alkaline protease variants. These variants have, when enumerating the alkaline protease from Bacillus lentus, variations in amino acid position 61, positions 199 and/or 211 and, optionally, at least one modification that contributes to the stabilization of the molecule, said modification preferably being point mutations in positions 3 and/or 4. Particularly preferred are variants S3T/V41/G61A/V199] and S3T/V41/G61A/V1991/L211D of B. lentus alkaline protease. The invention also relates to the possible use of these enzymes in diverse technical processes and, in particular, to detergents and cleansers containing these novel alkaline protease variants.
摘要翻译：本发明涉及新的碱性蛋白酶变体。当列举来自迟缓芽孢杆菌的碱性蛋白酶时，这些变体具有氨基酸位置61，位置199和/或211的变化，和任选地至少一个有助于分子稳定化的修饰，所述修饰优选是点突变位置3和/或4.特别优选的是变形芽孢杆菌碱性蛋白酶的变体S3T / V41 / G61A / V199]和S3T / V41 / G61A / V1991 / L211D。本发明还涉及这些酶在不同技术过程中的可能用途，特别涉及含有这些新型碱性蛋白酶变体的洗涤剂和清洁剂。

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