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1. 发明授权

US08708979B2 Implantable coupling device 失效
标题翻译：可植入耦合装置
公开(公告)号：US08708979B2
公开(公告)日：2014-04-29
申请号：US12904422
申请日：2010-10-14
申请人： Babak Honaryar , Marcos Borrell , Christopher S. Mudd , Joseph S. Raven , Sean Snow , Vern L. Vincent
发明人： Babak Honaryar , Marcos Borrell , Christopher S. Mudd , Joseph S. Raven , Sean Snow , Vern L. Vincent
IPC分类号： A61M37/00
CPC分类号： A61M39/0208 , A61B17/064 , A61F5/0056 , A61M39/04 , A61M2039/0223 , A61M2210/1053
摘要： The present invention provides a system for attaching a fluid access port to a patient. The system generally comprises an implantable access port and method for attaching an access port to a patient. In addition, a tube guard, tube shroud, tissue guard, porous coupling member and a prefabricated mesh member may be attached to the access port. For example, the prefabricated mesh may be coupled to the access port to facilitate securing the access port to the tissue of the patient.
摘要翻译：本发明提供了一种用于将流体进入口附接到患者的系统。该系统通常包括用于将访问端口附接到患者的可植入访问端口和方法。此外，管保护件，管罩，组织护罩，多孔连接构件和预制网状构件可以附接到进入端口。例如，预制网可以联接到接入端口以便于将接入端口固定到患者的组织。

2. 发明申请

US20110251453A1 IMPLANTABLE COUPLING DEVICE 失效
标题翻译：可植入耦合器件
公开(公告)号：US20110251453A1
公开(公告)日：2011-10-13
申请号：US12904422
申请日：2010-10-14
申请人： Babak Honaryar , Marcos Borrell , Christopher S. Mudd , Joseph S. Raven , Sean Snow , Vernon L. Vincent
发明人： Babak Honaryar , Marcos Borrell , Christopher S. Mudd , Joseph S. Raven , Sean Snow , Vernon L. Vincent
IPC分类号： A61F2/04
CPC分类号： A61M39/0208 , A61B17/064 , A61F5/0056 , A61M39/04 , A61M2039/0223 , A61M2210/1053
摘要： The present invention provides a system for attaching a fluid access port to a patient. The system generally comprises an implantable access port and method for attaching an access port to a patient. In addition, a tube guard, tube shroud, tissue guard, porous coupling member and a prefabricated mesh member may be attached to the access port. For example, the prefabricated mesh may be coupled to the access port to facilitate securing the access port to the tissue of the patient.
摘要翻译：本发明提供了一种用于将流体进入口附接到患者的系统。该系统通常包括用于将访问端口附接到患者的可植入访问端口和方法。此外，管保护件，管罩，组织护罩，多孔连接构件和预制网状构件可以附接到进入端口。例如，预制网可以联接到接入端口以便于将接入端口固定到患者的组织。

3. 发明申请

US20110218392A1 IMPLANTABLE BOTTOM EXIT PORT 失效
标题翻译：可伸缩底部出口口
公开(公告)号：US20110218392A1
公开(公告)日：2011-09-08
申请号：US13021099
申请日：2011-02-04
申请人： Babak HONARYAR , Marcos Borrell , Christopher S. Mudd , Joseph S. Raven , Jeff Allen , Sean Snow , Vernon L. Vincent
发明人： Babak HONARYAR , Marcos Borrell , Christopher S. Mudd , Joseph S. Raven , Jeff Allen , Sean Snow , Vernon L. Vincent
IPC分类号： A61F2/04
CPC分类号： A61M39/0208 , A61F5/0056 , A61M2039/0223 , A61M2039/0226 , A61M2039/0229
摘要： The present invention provides a system for attaching a fluid access port to a patient. The system generally comprises an implantable access port with a bottom exit port and method for attaching an access port to a patient. In addition, a tube guard, flexible tube exit port, tissue guard, and porous coupling member are disclosed.
摘要翻译：本发明提供了一种用于将流体进入口附接到患者的系统。该系统通常包括具有底部出口的可植入进入口和用于将进入端口附接到患者的方法。此外，公开了一种管保护件，柔性管出口，组织护罩和多孔连接构件。

4. 发明授权

US08715158B2 Implantable bottom exit port 失效
标题翻译：可植入底部出口
公开(公告)号：US08715158B2
公开(公告)日：2014-05-06
申请号：US13021099
申请日：2011-02-04
申请人： Babak Honaryar , Marcos Borrell , Christopher S. Mudd , Joseph S. Raven , Jeff Allen , Sean Snow , Vernon L. Vincent
发明人： Babak Honaryar , Marcos Borrell , Christopher S. Mudd , Joseph S. Raven , Jeff Allen , Sean Snow , Vernon L. Vincent
IPC分类号： A61F2/04
CPC分类号： A61M39/0208 , A61F5/0056 , A61M2039/0223 , A61M2039/0226 , A61M2039/0229
摘要： The present invention provides a system for attaching a fluid access port to a patient. The system generally comprises an implantable access port with a bottom exit port and method for attaching an access port to a patient. In addition, a tube guard, flexible tube exit port, tissue guard, and porous coupling member are disclosed.
摘要翻译：本发明提供了一种用于将流体进入口附接到患者的系统。该系统通常包括具有底部出口的可植入进入口和用于将进入端口附接到患者的方法。此外，公开了一种管保护件，柔性管出口，组织护罩和多孔连接构件。

5. 发明申请

US20120089172A1 RE-SHAPING INTRAGASTRIC IMPLANTS 审中-公开
标题翻译：重新形成INTRAGASTRIC植入物
公开(公告)号：US20120089172A1
公开(公告)日：2012-04-12
申请号：US13270016
申请日：2011-10-10
申请人： Mitchell H. Babkes , Zachary Dominguez , Christopher S. Mudd , Joseph S. Raven
发明人： Mitchell H. Babkes , Zachary Dominguez , Christopher S. Mudd , Joseph S. Raven
IPC分类号： A61M29/00
CPC分类号： A61F5/0036
摘要： The present application provides implantable intragastric devices for the treatment of obesity. The intragastric devices advantageously act as a volume-occupying device, and is able to survive implantation in a patient's stomach for a year or longer. In addition, the intragastric devices may be configured to stimulate an inner stomach wall and/or temporarily block the pylorus to slow gastric emptying and/or be rotationally variant, thereby encouraging different stimulation points on the inner wall of the stomach and limiting the stomach's ability to adapt over long term implantation. The intragastric devices may reshape the stomach cavity, such as by pushing on opposite sides so as to “planarize” the stomach. For instance, the device may be an inflated disk, or an implantable loop or a springy coil that may be straightened for delivery/extraction yet assume the loop or coil shape upon implant.
摘要翻译：本申请提供了用于治疗肥胖的可植入胃内装置。胃内装置有利地用作体积占据装置，并且能够在患者的胃中植入一年或更长时间。此外，胃内装置可以被配置为刺激内部胃壁和/或临时阻塞幽门以减缓胃排空和/或旋转变异，由此鼓励胃内壁上的不同刺激点并限制胃的能力适应长期植入。胃内装置可以重新形成胃腔，例如通过推动相对侧以便使胃平坦化。例如，该装置可以是充气盘，或可植入环或弹性线圈，其可以被拉直以用于递送/提取，但在植入时呈现环或线圈形状。

6. 发明授权

US08603028B2 Injection device having an angled tip portion 有权
标题翻译：具有倾斜尖端部分的注射装置
公开(公告)号：US08603028B2
公开(公告)日：2013-12-10
申请号：US13422919
申请日：2012-03-16
申请人： Christopher S. Mudd , Mitchell H. Babkes , Zachary P. Dominguez , Michael J. Prichard , Martha E. Llewellyn , Shaohui Qiu , Lee F. Powers , Brett R. Johnson
发明人： Christopher S. Mudd , Mitchell H. Babkes , Zachary P. Dominguez , Michael J. Prichard , Martha E. Llewellyn , Shaohui Qiu , Lee F. Powers , Brett R. Johnson
IPC分类号： A61M37/00
CPC分类号： A61M5/2066 , A61M5/19 , A61M5/20 , A61M5/2053 , A61M5/24 , A61M5/31 , A61M2005/341 , A61M2205/50
摘要： In one embodiment, the handheld injection device includes a first housing having a first axis and a second housing having a second axis. In one embodiment, the second housing is configured to support a needle. In one embodiment, the first axis and a second axis form an adjustable angle between about 180 degrees and about 90 degrees.
摘要翻译：在一个实施例中，手持式注射装置包括具有第一轴线的第一壳体和具有第二轴线的第二壳体。在一个实施例中，第二壳体构造成支撑针头。在一个实施例中，第一轴线和第二轴线在约180度和约90度之间形成可调节的角度。

7. 发明授权

US08535278B2 Extendable plunger rod for medical syringe 有权
标题翻译：医用注射器可伸缩柱塞杆
公开(公告)号：US08535278B2
公开(公告)日：2013-09-17
申请号：US12944102
申请日：2010-11-11
申请人： Christopher S. Mudd
发明人： Christopher S. Mudd
IPC分类号： A61M5/315
CPC分类号： A61M5/31511 , A61M5/31505 , A61M2005/31518
摘要： An extendible plunger rod for use with a syringe is provided. Example plunger rods may include an outer plunger rod with a proximal end and a distal end, the outer plunger rod having an inner cavity; an inner plunger rod, housed at least partially within the inner cavity of the outer plunger rod; a compression spring disposed within the inner cavity of the outer plunger rod and between the proximal end of the outer plunger rod, and the inner plunger rod, the compression spring configured to exert force tending to push the inner plunger rod in a direction distal to the outer plunger rod; and a locking mechanism, the locking mechanism configured to prevent movement of the inner plunger rod relative to the outer plunger rod while both the inner and outer plunger rods are depressed into a syringe body, until the outer plunger rod has been depressed at least a first predetermined distance into the syringe body.
摘要翻译：提供了一种用于注射器的可伸缩柱塞杆。示例性柱塞杆可以包括具有近端和远端的外柱塞杆，外柱塞杆具有内腔; 内柱塞杆，至少部分地容纳在外柱塞杆的内腔内; 设置在所述外柱塞杆的所述内腔内并且位于所述外柱塞杆的近端与所述内柱塞杆之间的压缩弹簧，所述压缩弹簧构造成施加倾向于沿着所述外柱塞杆的远侧方向推动所述内柱塞杆的力外柱塞杆; 以及锁定机构，所述锁定机构构造成防止所述内柱塞杆相对于所述外柱塞杆的移动，同时所述内柱塞杆和所述外柱塞杆都被压入注射器主体中，直到所述外柱塞杆已经被压下至少第一到注射器主体的预定距离。

8. 发明授权

US08513216B2 Polysaccharide gel formulation having increased longevity 有权
公开(公告)号：US08513216B2
公开(公告)日：2013-08-20
申请号：US12558270
申请日：2009-09-11
申请人： Dimitrios Stroumpoulis , Christopher S. Mudd , Ahmet Tezel
发明人： Dimitrios Stroumpoulis , Christopher S. Mudd , Ahmet Tezel
IPC分类号： A61K31/70
CPC分类号： A61L27/26 , A61K8/042 , A61K8/492 , A61K8/60 , A61K8/602 , A61K8/676 , A61K8/678 , A61K8/73 , A61K8/731 , A61K8/735 , A61K8/736 , A61K31/715 , A61K31/717 , A61K31/721 , A61K31/727 , A61K31/728 , A61K31/737 , A61K31/738 , A61K47/183 , A61K47/26 , A61K47/36 , A61K47/38 , A61K47/42 , A61K2800/522 , A61L27/505 , A61Q19/08 , C08B37/0072 , C08J3/075 , C08J2305/08 , C08K5/053 , C08L5/08 , C08L2205/02
摘要： Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide. In some embodiments, the incorporating step comprises 1) mixing the at least one inhibitor with the at least one polysaccharide at a highly hydrated state thereby encapsulating the at least one inhibitor in a polysaccharide network, and 2) dehydrating the polysaccharide network thereby controlling release kinetics or final swell ratio. In another embodiment, the incorporating step comprises 1) encapsulating at least one inhibitor into a biocompatible or biodegradable vessel and 2) combining the polysaccharide and the vessel into a gel formulation. The polysaccharide gel formulations described herein can be used for a variety of cosmetic applications.

9. 发明申请

US20120330245A1 SLOTTED SYRINGE 失效
标题翻译：缝制的SYRINGE
公开(公告)号：US20120330245A1
公开(公告)日：2012-12-27
申请号：US13604896
申请日：2012-09-06
申请人： Christopher S. Mudd
发明人： Christopher S. Mudd
IPC分类号： A61M5/315
CPC分类号： A61M5/3137 , A61M5/3129 , A61M5/3135 , A61M5/31511 , A61M5/3158 , A61M2005/3139 , A61M2005/31518 , A61M2005/5006 , A61M2202/06
摘要： A syringe is disclosed. The syringe may include a syringe body, a first slot formed in the syringe body, a first sleeve covering the first slot, a thumb grip including a first slot guide disposed in the first slot, the thumb grip shaped to slide from a first position near the distal end of the syringe body toward a second position near the proximal end of the syringe body, and a plunger disposed in the fluid chamber of the syringe body. The plunger is configured to move towards the proximal end of the syringe body in response to pressure applied by a user to the thumb grip and includes a first plunger slot guide.
摘要翻译：公开了一种注射器。注射器可以包括注射器主体，形成在注射器主体中的第一狭槽，覆盖第一狭槽的第一套筒，拇指手柄，其包括设置在第一槽中的第一槽导向件，形状为从第一位置附近滑动的拇指夹注射器主体的远端靠近注射器主体的近端的第二位置，以及设置在注射器主体的流体室中的柱塞。柱塞构造成响应于使用者施加到拇指把手的压力而朝向注射器本体的近端移动，并且包括第一柱塞狭槽引导件。

10. 发明申请

US20120095494A1 INTRAGASTRIC IMPLANTS WITH COLLAPSIBLE FRAMES 有权
标题翻译：具有可拉框的INTRAGASTRIC植入物
公开(公告)号：US20120095494A1
公开(公告)日：2012-04-19
申请号：US13272131
申请日：2011-10-12
申请人： Zachary Dominguez , Mitchell H. Babkes , Justin Schwab , Christopher S. Mudd , Jason Hoover
发明人： Zachary Dominguez , Mitchell H. Babkes , Justin Schwab , Christopher S. Mudd , Jason Hoover
IPC分类号： A61M29/00 , A61M29/02
CPC分类号： A61F5/0036 , A61F5/0033 , A61F5/0079 , A61F5/0086 , A61F5/0089
摘要： Transoral obesity treatment devices and related methods for operation thereof are described which occupy space within a stomach and/or stimulate the stomach wall. The transoral obesity treatment devices and related methods are intended to assist a patient in maintaining a healthy body weight. Features of the devices include insertion transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The life span of these devices may be material-dependent upon long-term survivability within an acidic stomach, but is intended to last one year or longer. The devices have the capacity to vary in size and are desirably self-actuating in that they change shape and/or volume using internal motors or actuators. The changing character of the devices helps prevent the person's stomach from compensating for the implant, such as sometimes happens with static intragastric devices.
摘要翻译：描述了跨腹部肥胖症治疗装置及其相关操作方法，其占据胃内的空间和/或刺激胃壁。经腹肥胖治疗装置和相关方法旨在帮助患者保持健康的体重。器件的特征包括经皮插入和无侵入性手术，无相关患者的侵入性手术风险，无明显的患者不适。这些装置的使用寿命可能依赖于酸性胃内的长期生存能力，但意图持续一年或更长时间。这些装置具有在尺寸上变化的能力，并且希望是自动致动，因为它们使用内部电动机或致动器改变形状和/或体积。设备的变化特征有助于防止人的胃部补偿植入物，例如有时会发生静态胃内装置。

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