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1. 发明申请

US20100184201A1 MEASURING UNIT FOR MEASURING CHARACTERISTICS OF A SAMPLE LIQUID, IN PARTICULAR VISCOELASTIC CHARACTERISTICS OF A BLOOD SAMPLE 有权
标题翻译：用于测量样品特性的测量单元，特别是血液样品的粘弹性特征
公开(公告)号：US20100184201A1
公开(公告)日：2010-07-22
申请号：US12688306
申请日：2010-01-15
申请人： Axel Schubert , José Javier Romero-Galeano , Max Kessler
发明人： Axel Schubert , José Javier Romero-Galeano , Max Kessler
IPC分类号： C12M3/00
CPC分类号： G01N33/4905
摘要： The present invention is directed to a measuring unit, for measuring characteristics of a sample liquid, comprising a support member, having at least one upper bearing arm, with an upper bearing unit, at least one lower bearing arm, with a lower bearing unit, and a base, for being attachable to a respective measuring system; a shaft, having shaft toes and being rotatably supported about a rotation axis, by said upper bearing unit, and said lower bearing unit, wherein said upper bearing unit, said lower bearing unit, and said shaft toes form toe bearings, respectively; an interface member, having a detecting element, and a drive element, said interface member, being fixed on said shaft, and being connected to a coupling shaft, with a probe connector section, for measuring characteristics of said sample liquid; wherein said interface member, and the coupling shaft, are coaxially aligned with said shaft.
摘要翻译：本发明涉及一种用于测量样品液体的特性的测量单元，其包括具有至少一个上支承臂的支撑构件，具有上轴承单元，至少一个下支承臂和下轴承单元，和基座，用于连接到相应的测量系统; 具有轴脚趾并且通过所述上轴承单元和所述下轴承单元围绕旋转轴线可旋转地支撑的轴，其中所述上轴承单元，所述下轴承单元和所述轴脚趾分别形成脚趾轴承; 具有检测元件的接口构件和驱动元件，所述接口构件固定在所述轴上，并且与连接轴连接，用于测量所述样品液体的特性的探针连接器部分; 其中所述接口构件和所述联接轴与所述轴同轴对准。

2. 发明申请

US20100154520A1 CARTRIDGE DEVICE FOR A MEASURING SYSTEM FOR MEASURING VISCOELASTIC CHARACTERISTICS OF A SAMPLE LIQUID, A CORRESPONDING MEASURING SYSTEM, AND A CORRESPONDING METHOD 有权
标题翻译：用于测量样品液体粘度特性的测量系统的测量装置，相应的测量系统以及相应的方法
公开(公告)号：US20100154520A1
公开(公告)日：2010-06-24
申请号：US12640376
申请日：2009-12-17
申请人： Axel Schubert , José Javier Romero-Galeano , Max Kessler
发明人： Axel Schubert , José Javier Romero-Galeano , Max Kessler
IPC分类号： G01N11/14
CPC分类号： G01N33/86 , B01L3/502 , B01L3/52 , B01L2200/10 , B01L2300/0627 , B01L2300/0636 , B01L2300/0861 , B01L2300/087 , B01L2400/0475 , G01N11/00 , G01N11/14 , G01N33/4905 , G01N2011/0046 , G01N2333/96458 , G01N2800/224
摘要： The present invention is directed to a cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, in particular a blood sample, comprising a cartridge body having at least one measurement cavity formed therein and having at least one probe element arranged in said at least one measurement cavity for performing a test on said sample liquid; and a cover being attachable on said cartridge body; wherein said cover covers at least partially said at least one measurement cavity and forms a retaining element for retaining said probe element in a predetermined position within said at least one measurement cavity. The invention is directed to a measurement system and a method for measuring viscoelastic characteristics of a sample liquid.
摘要翻译：本发明涉及一种用于测量样品液体，特别是血液样品的粘弹特性的测量系统的盒装置，包括：一个盒本体，其具有形成在其中的至少一个测量腔，并且具有至少一个探针元件，用于对所述样品液体进行测试的至少一个测量腔; 以及可附接在所述盒体上的盖子; 其中所述盖至少部分地覆盖所述至少一个测量腔，并且形成用于将所述探针元件保持在所述至少一个测量空腔内的预定位置的保持元件。本发明涉及一种用于测量样品液体的粘弹性特征的测量系统和方法。

3. 发明授权

US08448499B2 Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method 有权
公开(公告)号：US08448499B2
公开(公告)日：2013-05-28
申请号：US12640376
申请日：2009-12-17
申请人： Axel Schubert , José Javier Romero-Galeano , Max Kessler
发明人： Axel Schubert , José Javier Romero-Galeano , Max Kessler
IPC分类号： G01N11/14
CPC分类号： G01N33/86 , B01L3/502 , B01L3/52 , B01L2200/10 , B01L2300/0627 , B01L2300/0636 , B01L2300/0861 , B01L2300/087 , B01L2400/0475 , G01N11/00 , G01N11/14 , G01N33/4905 , G01N2011/0046 , G01N2333/96458 , G01N2800/224
摘要： The present invention is directed to a cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, in particular a blood sample, comprising a cartridge body having at least one measurement cavity formed therein and having at least one probe element arranged in said at least one measurement cavity for performing a test on said sample liquid; and a cover being attachable on said cartridge body; wherein said cover covers at least partially said at least one measurement cavity and forms a retaining element for retaining said probe element in a predetermined position within said at least one measurement cavity. The invention is directed to a measurement system and a method for measuring viscoelastic characteristics of a sample liquid.

4. 发明授权

US08383045B2 Measuring unit for measuring characteristics of a sample liquid, in particular viscoelastic characteristics of a blood sample 有权
标题翻译：用于测量样品液体特性的测量单元，特别是血液样品的粘弹性特征
公开(公告)号：US08383045B2
公开(公告)日：2013-02-26
申请号：US12688306
申请日：2010-01-15
申请人： Axel Schubert , José Javier Romero-Galeano , Max Kessler
发明人： Axel Schubert , José Javier Romero-Galeano , Max Kessler
IPC分类号： G01N33/00 , G01N33/86 , G01N11/14 , G01N37/00
CPC分类号： G01N33/4905
摘要： The present invention is directed to a measuring unit, for measuring characteristics of a sample liquid, comprising a support member, having at least one upper bearing arm, with an upper bearing unit, at least one lower bearing arm, with a lower bearing unit, and a base, for being attachable to a respective measuring system; a shaft, having shaft toes and being rotatably supported about a rotation axis, by said upper bearing unit, and said lower bearing unit, wherein said upper bearing unit, said lower bearing unit, and said shaft toes form toe bearings, respectively; an interface member, having a detecting element, and a drive element, said interface member, being fixed on said shaft, and being connected to a coupling shaft, with a probe connector section, for measuring characteristics of said sample liquid; wherein said interface member, and the coupling shaft, are coaxially aligned with said shaft.
摘要翻译：本发明涉及一种用于测量样品液体的特性的测量单元，其包括具有至少一个上支承臂的支撑构件，具有上轴承单元，至少一个下支承臂和下轴承单元，和基座，用于连接到相应的测量系统; 具有轴脚趾并且通过所述上轴承单元和所述下轴承单元围绕旋转轴线可旋转地支撑的轴，其中所述上轴承单元，所述下轴承单元和所述轴脚趾分别形成脚趾轴承; 具有检测元件的接口构件和驱动元件，所述接口构件固定在所述轴上，并且与连接轴连接，用于测量所述样品液体的特性的探针连接器部分; 其中所述接口构件和所述联接轴与所述轴同轴对准。

5. 发明申请

US20090130645A1 METHOD FOR ASSESSING THE FIBRINOGEN CONTRIBUTION IN COAGULATION 审中-公开
标题翻译：评估凝血酶原纤维蛋白原的方法
公开(公告)号：US20090130645A1
公开(公告)日：2009-05-21
申请号：US12275757
申请日：2008-11-21
申请人： Axel Schubert , Martin Schwaiger , Max Kessler
发明人： Axel Schubert , Martin Schwaiger , Max Kessler
IPC分类号： A01N1/02
CPC分类号： G01N33/86 , G01N2333/745 , G01N2333/75
摘要： The present invention is directed to a diagnostic method for the determination of a coagulopathy in a patient, in particular, for calculating the individual need of blood components, preferably blood platelets and/or fibrinogen and/or Factor XIII, which has to be substituted in a patient.
摘要翻译：本发明涉及一种用于确定患者凝血病的诊断方法，特别是用于计算血液成分，优选血小板和/或纤维蛋白原和/或因子XIII的个体需要，其必须被置换病人。

6. 发明授权

US08322195B2 Apparatus and method for measuring the coagulation characteristics of a test liquid 有权
标题翻译：用于测量测试液体的凝固特性的装置和方法
公开(公告)号：US08322195B2
公开(公告)日：2012-12-04
申请号：US12520034
申请日：2007-12-18
申请人： Martin Glauner , Axel Schubert , Max Kessler
发明人： Martin Glauner , Axel Schubert , Max Kessler
IPC分类号： G01N11/14 , G01N37/00
CPC分类号： G01N33/4905
摘要： An apparatus and a method for measuring the coagulation characteristics of a test liquid (1), in particular of a blood sample, is provided. According to the present invention standardized geometrical dimensions of a cup (2) and a respective pin (3) are modified for receiving maximum elasticity signal per volume test liquid without resulting in irreversible inelastic effects. In particular, the test liquid gap (8) between the cup (2) and the pin (3) is reduced, the diameter of the cup (2) and the pin (3) are increased and/or the geometry of test liquid accommodating portions (7; 10; 10′) are optimized for increasing the ratio between signal amplitude and a needed amount of test liquid (1) compared to standardized equipment.
摘要翻译：提供了一种用于测量特别是血液样本的测试液体（1）的凝结特性的装置和方法。根据本发明，改变了杯（2）和相应销（3）的标准化几何尺寸以接收每体积测试液体的最大弹性信号，而不会导致不可逆的非弹性效应。特别地，杯（2）和销（3）之间的测试液隙（8）减小，杯（2）和销（3）的直径增加和/或容纳测试液体的几何形状优化部分（7; 10; 10'），以增加与标准化设备相比的信号幅度与所需量的测试液体（1）之间的比率。

7. 发明申请

US20100170327A1 APPARATUS AND METHOD FOR MEASURING THE COAGULATION CHARACTERISTICS OF A TEST LIQUID 有权
标题翻译：测定液体凝集特性的装置和方法
公开(公告)号：US20100170327A1
公开(公告)日：2010-07-08
申请号：US12520034
申请日：2007-12-18
申请人： Martin Glauner , Axel Schubert , Max Kessler
发明人： Martin Glauner , Axel Schubert , Max Kessler
IPC分类号： G01N11/16
CPC分类号： G01N33/4905
摘要： An apparatus and a method for measuring the coagulation characteristics of a test liquid (1), in particular of a blood sample, is provided. According to the present invention standardized geometrical dimensions of a cup (2) and a respective pin (3) are modified for receiving maximum elasticity signal per volume test liquid without resulting in irreversible inelastic effects. In particular, the test liquid gap (8) between the cup (2) and the pin (3) is reduced, the diameter of the cup (2) and the pin (3) are increased and/or the geometry of test liquid accommodating portions (7; 10; 10′) are optimized for increasing the ratio between signal amplitude and a needed amount of test liquid (1) compared to standardized equipment.
摘要翻译：提供了一种用于测量特别是血液样本的测试液体（1）的凝结特性的装置和方法。根据本发明，改变了杯（2）和相应销（3）的标准化几何尺寸以接收每体积测试液体的最大弹性信号，而不会导致不可逆的非弹性效应。特别地，杯（2）和销（3）之间的测试液隙（8）减小，杯（2）和销（3）的直径增加和/或容纳测试液体的几何形状优化部分（7; 10; 10'），以增加与标准化设备相比的信号幅度与所需量的测试液体（1）之间的比率。

8. 发明申请

US20100190193A1 DIAGNOSTIC COMPOSITION AND ITS USE IN THE DETERMINATION OF COAGULATION CHARACTERISTICS OF A TEST LIQUID 审中-公开
标题翻译：诊断组合物及其在测定液体凝集特性中的应用
公开(公告)号：US20100190193A1
公开(公告)日：2010-07-29
申请号：US12522364
申请日：2008-01-31
申请人： Andreas Calatzis , Martin Glauner , Axel Schubert , Max Kessler
发明人： Andreas Calatzis , Martin Glauner , Axel Schubert , Max Kessler
IPC分类号： C12Q1/56 , C12M1/34
CPC分类号： G01N33/86 , G01N2333/745
摘要： The present invention is directed to a diagnostic composition for use in the viscoelastic analysis of a test liquid, and to a container (1) comprising same. The composition comprises at least an activator of coagulation, and, optionally CaCl2 an optionally, one or more inhibitors and/or coagulation components, wherein the composition is present as an essentially dry mixture of all constituents and in an amount sufficient for performing one single viscoelastic analysis of a specified blood or plasma sample. The present invention is further directed to a method of performing a viscoelastic analysis on a test liquid, and to the use of the diagnostic composition in such a method.
摘要翻译：本发明涉及用于测试液体的粘弹性分析的诊断组合物，以及包含该液体的容器（1）。该组合物包含至少一种凝固活化剂，以及任选的CaCl 2，任选的一种或多种抑制剂和/或凝结组分，其中所述组合物作为所有组分的基本上干燥的混合物存在并且以足以实施单一粘弹性分析指定的血液或血浆样品。本发明还涉及对这种方法对测试液体进行粘弹性分析的方法和诊断组合物的用途。

9. 发明授权

US07402910B2 Solder, microelectromechanical component and device, and a process for producing a component or device 有权
标题翻译：焊接，微机电部件和装置，以及用于制造部件或装置的方法
公开(公告)号：US07402910B2
公开(公告)日：2008-07-22
申请号：US10789423
申请日：2004-02-27
申请人： Harald Böttner , Axel Schubert , Martin Jaegle
发明人： Harald Böttner , Axel Schubert , Martin Jaegle
IPC分类号： H01L23/48 , H01L23/52 , H01L29/40
CPC分类号： B81C3/001 , B23K35/0238 , B23K35/264 , H01L23/38 , H01L23/488 , H01L2924/0002 , H01L2924/00
摘要： A solder, in particular a thin-film solder, for joining microelectromechanical components, wherein the solder is a eutectic mixture of gold and bismuth. Components and devices joined by a solder of this type are also disclosed, in addition to processes for producing such components or devices.
摘要翻译：用于接合微电子机械部件的焊料，特别是薄膜焊料，其中焊料是金和铋的共晶混合物。除了用于制造这种部件或装置的方法之外，还公开了通过这种类型的焊料连接的部件和装置。

10. 发明授权

US06818470B1 Process for producing a thermoelectric converter 失效
标题翻译：制造热电转换器的方法
公开(公告)号：US06818470B1
公开(公告)日：2004-11-16
申请号：US09806424
申请日：2001-07-24
申请人： Bruno Acklin , Karl-Heinz Schlereth , Harald Boettner , Axel Schubert
发明人： Bruno Acklin , Karl-Heinz Schlereth , Harald Boettner , Axel Schubert
IPC分类号： H01L2716
CPC分类号： H01L35/32 , H01L35/34
摘要： Method for fabricating a thermoelectric converter having a plurality of series-connected thermoelement cells, which are connected in series with one another by means of a plurality of first electrical conductor tracks (3) and each of which has a first body (4) made of thermoelectric material of a first conduction type and a second body (5) made of thermoelectric material of a second conduction type. The thermoelement cells are fabricated by means of method steps appertaining to semiconductor technology.
摘要翻译：一种用于制造具有多个串联连接的热电元件的热电转换器的方法，它们通过多个第一电导体轨道（3）彼此串联连接，并且每个具有第一主体（4），所述第一主体第一导电类型的热电材料和由第二导电类型的热电材料制成的第二主体（5）。通过与半导体技术相关的方法步骤制造热电偶电池。

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