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1. 发明申请

US20100190193A1 DIAGNOSTIC COMPOSITION AND ITS USE IN THE DETERMINATION OF COAGULATION CHARACTERISTICS OF A TEST LIQUID 审中-公开
标题翻译：诊断组合物及其在测定液体凝集特性中的应用
公开(公告)号：US20100190193A1
公开(公告)日：2010-07-29
申请号：US12522364
申请日：2008-01-31
申请人： Andreas Calatzis , Martin Glauner , Axel Schubert , Max Kessler
发明人： Andreas Calatzis , Martin Glauner , Axel Schubert , Max Kessler
IPC分类号： C12Q1/56 , C12M1/34
CPC分类号： G01N33/86 , G01N2333/745
摘要： The present invention is directed to a diagnostic composition for use in the viscoelastic analysis of a test liquid, and to a container (1) comprising same. The composition comprises at least an activator of coagulation, and, optionally CaCl2 an optionally, one or more inhibitors and/or coagulation components, wherein the composition is present as an essentially dry mixture of all constituents and in an amount sufficient for performing one single viscoelastic analysis of a specified blood or plasma sample. The present invention is further directed to a method of performing a viscoelastic analysis on a test liquid, and to the use of the diagnostic composition in such a method.
摘要翻译：本发明涉及用于测试液体的粘弹性分析的诊断组合物，以及包含该液体的容器（1）。该组合物包含至少一种凝固活化剂，以及任选的CaCl 2，任选的一种或多种抑制剂和/或凝结组分，其中所述组合物作为所有组分的基本上干燥的混合物存在并且以足以实施单一粘弹性分析指定的血液或血浆样品。本发明还涉及对这种方法对测试液体进行粘弹性分析的方法和诊断组合物的用途。

2. 发明申请

US20100170327A1 APPARATUS AND METHOD FOR MEASURING THE COAGULATION CHARACTERISTICS OF A TEST LIQUID 有权
标题翻译：测定液体凝集特性的装置和方法
公开(公告)号：US20100170327A1
公开(公告)日：2010-07-08
申请号：US12520034
申请日：2007-12-18
申请人： Martin Glauner , Axel Schubert , Max Kessler
发明人： Martin Glauner , Axel Schubert , Max Kessler
IPC分类号： G01N11/16
CPC分类号： G01N33/4905
摘要： An apparatus and a method for measuring the coagulation characteristics of a test liquid (1), in particular of a blood sample, is provided. According to the present invention standardized geometrical dimensions of a cup (2) and a respective pin (3) are modified for receiving maximum elasticity signal per volume test liquid without resulting in irreversible inelastic effects. In particular, the test liquid gap (8) between the cup (2) and the pin (3) is reduced, the diameter of the cup (2) and the pin (3) are increased and/or the geometry of test liquid accommodating portions (7; 10; 10′) are optimized for increasing the ratio between signal amplitude and a needed amount of test liquid (1) compared to standardized equipment.
摘要翻译：提供了一种用于测量特别是血液样本的测试液体（1）的凝结特性的装置和方法。根据本发明，改变了杯（2）和相应销（3）的标准化几何尺寸以接收每体积测试液体的最大弹性信号，而不会导致不可逆的非弹性效应。特别地，杯（2）和销（3）之间的测试液隙（8）减小，杯（2）和销（3）的直径增加和/或容纳测试液体的几何形状优化部分（7; 10; 10'），以增加与标准化设备相比的信号幅度与所需量的测试液体（1）之间的比率。

3. 发明授权

US08322195B2 Apparatus and method for measuring the coagulation characteristics of a test liquid 有权
标题翻译：用于测量测试液体的凝固特性的装置和方法
公开(公告)号：US08322195B2
公开(公告)日：2012-12-04
申请号：US12520034
申请日：2007-12-18
申请人： Martin Glauner , Axel Schubert , Max Kessler
发明人： Martin Glauner , Axel Schubert , Max Kessler
IPC分类号： G01N11/14 , G01N37/00
CPC分类号： G01N33/4905
摘要： An apparatus and a method for measuring the coagulation characteristics of a test liquid (1), in particular of a blood sample, is provided. According to the present invention standardized geometrical dimensions of a cup (2) and a respective pin (3) are modified for receiving maximum elasticity signal per volume test liquid without resulting in irreversible inelastic effects. In particular, the test liquid gap (8) between the cup (2) and the pin (3) is reduced, the diameter of the cup (2) and the pin (3) are increased and/or the geometry of test liquid accommodating portions (7; 10; 10′) are optimized for increasing the ratio between signal amplitude and a needed amount of test liquid (1) compared to standardized equipment.
摘要翻译：提供了一种用于测量特别是血液样本的测试液体（1）的凝结特性的装置和方法。根据本发明，改变了杯（2）和相应销（3）的标准化几何尺寸以接收每体积测试液体的最大弹性信号，而不会导致不可逆的非弹性效应。特别地，杯（2）和销（3）之间的测试液隙（8）减小，杯（2）和销（3）的直径增加和/或容纳测试液体的几何形状优化部分（7; 10; 10'），以增加与标准化设备相比的信号幅度与所需量的测试液体（1）之间的比率。

4. 发明授权

US07745223B2 Device with novel and improved surface properties 有权
标题翻译：具有新颖和改进的表面性能的装置
公开(公告)号：US07745223B2
公开(公告)日：2010-06-29
申请号：US11200494
申请日：2005-08-10
申请人： Axel Schubert , Stefan Wurlitzer , Andreas Calatzis , Martin Glauner
发明人： Axel Schubert , Stefan Wurlitzer , Andreas Calatzis , Martin Glauner
IPC分类号： G01N33/86
CPC分类号： B29C59/14 , B01L3/508 , G01N33/4905 , Y10T436/25
摘要： To increase the adhesion strength of coagulated blood on a surface by increasing the surface interaction of blood-inherent components like fibrin/fibrinogen and thrombocytes it is described to treat the surface by exposing it to ionized atoms or molecules. The surface treatment according to the invention is applied on plastic disposables used in blood diagnostics (e.g. hemostasis analysis) as well as medical implants like artery sealings. The improved blood clot adhesion results in higher diagnostic security due to reduced measurement failure (e.g., for patients with increased thrombocyte content) and in better significance of special tests (e.g., hyperfibrinolysis diagnosis).
摘要翻译：为了通过增加血液固有组分如纤维蛋白/纤维蛋白原和凝血细胞的表面相互作用来增加凝血血液在表面上的粘附强度，可以通过将其暴露于离子化的原子或分子来处理表面。根据本发明的表面处理应用于血液诊断（例如止血分析）中使用的塑料一次性物品以及诸如动脉密封的医疗植入物。由于减少的测量失败（例如，对于具有增加的血小板含量的患者）和特别测试（例如，超纤维蛋白溶解诊断）的更好的显着性，改善的血块粘附导致更高的诊断安全性。

5. 发明申请

US20060034734A1 Device with novel and improved surface properties 有权
标题翻译：具有新颖和改进的表面性能的装置
公开(公告)号：US20060034734A1
公开(公告)日：2006-02-16
申请号：US11200494
申请日：2005-08-10
申请人： Axel Schubert , Stefan Wurlitzer , Andreas Calatzis , Martin Glauner
发明人： Axel Schubert , Stefan Wurlitzer , Andreas Calatzis , Martin Glauner
IPC分类号： B01L11/00
CPC分类号： B29C59/14 , B01L3/508 , G01N33/4905 , Y10T436/25
摘要： To increase the adhesion strength of coagulated blood on a surface by increasing the surface interaction of blood-inherent components like fibrin/fibrinogen and thrombocytes it is described to treat the surface by exposing it to ionized atoms or molecules. The surface treatment according to the invention is applied on plastic disposables used in blood diagnostics (e.g. haemostasis analysis) as well as medical implants like artery sealings. The improved blood clot adhesion results in higher diagnostic security due to reduced measurement failure (e.g., for patients with increased thrombocyte content) and in better significance of special tests (e.g., hyperfibrinolysis diagnosis).
摘要翻译：为了通过增加血液固有组分如纤维蛋白/纤维蛋白原和凝血细胞的表面相互作用来增加凝血血液在表面上的粘附强度，可以通过将其暴露于离子化的原子或分子来处理表面。根据本发明的表面处理用于血液诊断（例如止血分析）中使用的塑料一次性物品以及诸如动脉密封的医疗植入物。由于减少的测量失败（例如，对于具有增加的血小板含量的患者）和特别测试（例如，超纤维蛋白溶解诊断）的更好的显着性，改善的血块粘附导致更高的诊断安全性。

6. 发明授权

US6006073A Apparatus and method for improvement of transmission quality in a point-to-multipoint radio transmission system 失效
标题翻译：用于改善点对多点无线电传输系统中传输质量的装置和方法
公开(公告)号：US6006073A
公开(公告)日：1999-12-21
申请号：US966989
申请日：1997-11-10
申请人： Martin Glauner , Tillmann Eckstein , Andreas Bollmann
发明人： Martin Glauner , Tillmann Eckstein , Andreas Bollmann
IPC分类号： H04B7/005 , H04L1/00 , H04Q7/20 , H04B17/00
CPC分类号： H04W52/24 , H04L1/0001 , H04L1/0003 , H04L1/0009 , H04L1/0015 , H04W52/42 , H04L2001/0093
摘要： The radio transmission system includes at least one base station (BS1,BS2) and several participant stations (T111, . . . ,T222), in which the radio transmission range (Z1,Z2) belonging to each base station (BS1, BS2) is divided into several sectors (S11, . . . ,S22). The radio transmission system performs an automatic interference analysis in which a test channel is established between each participant station (T111, . . . ,T222) and all those sectors (S11, . . . ,S22) which cause interferences with the concerned participant station. A signal path-attenuation value is determined from the transmission power and received power of the test channel for each signal path between the participant stations (T111, . . . ,T222) and sectors (S11, . . . ,S22) and a carrier signal-to-noise ratio is determined for each participant station (T111, . . . ,T222) from all the signal path attenuation values contributing to it. When this carrier signal-to-noise ratio is below a predetermined threshold, a more robust type of modulation is used for the data signal transmission between the concerned participant station (T111, . . . ,T222) and the sector (S11, . . . ,S22) associated with it and/or the transmitted signal carrier is changed to another different frequency channel, for at least the sector (S11, . . . ,S22) which causes the greatest interference.
摘要翻译：无线电传输系统包括属于每个基站（BS1，BS2）的无线电传输范围（Z1，Z2）的至少一个基站（BS1，BS2）和多个参与者站（T111，...，T222）被划分为几个扇区（S11，...，S22）。无线电传输系统执行自动干扰分析，其中在每个参与者站（T111，...，T222）和所有这些扇区（S11，...，S22）之间建立测试信道，导致与相关参与站的干扰。信号路径衰减值根据参与者站（T111，...，T222）和扇区（S11，...，S22）之间的每个信号路径的测试信道的发送功率和接收功率确定，并且载波从对其贡献的所有信号路径衰减值，为每个参与台（T111，...，T222）确定信噪比。当该载波信噪比低于预定阈值时，对于相关参与站（T111，...，T222）和扇区（S11，...）之间的数据信号传输，采用更稳健的调制方式。至少与造成最大干扰的扇区（S11，...，S22）相关联和/或发送的信号载波被改变到另一个不同的频率信道。

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