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1. 发明授权

US06212434B1 Single pass lead system 失效
公开(公告)号：US06212434B1
公开(公告)日：2001-04-03
申请号：US09120824
申请日：1998-07-22
申请人： Avram Scheiner , William Hsu , David M. Flynn , Qingsheng Zhu , John E. Heil , Ronald W. Heil, Jr. , Curtis C. Lindstrom , Robert S. Booker, III , Yayun Lin , Peter T. Kelley , Jay A. Warren , Gerrard M. Carlson , Carol Werlein , Aaron W. Janke , Mary Lee Cole , Jeffrey T. Bartig , Gary W. Goebel , Douglas A. Heitkamp , Randall M. Peterfeso
发明人： Avram Scheiner , William Hsu , David M. Flynn , Qingsheng Zhu , John E. Heil , Ronald W. Heil, Jr. , Curtis C. Lindstrom , Robert S. Booker, III , Yayun Lin , Peter T. Kelley , Jay A. Warren , Gerrard M. Carlson , Carol Werlein , Aaron W. Janke , Mary Lee Cole , Jeffrey T. Bartig , Gary W. Goebel , Douglas A. Heitkamp , Randall M. Peterfeso
IPC分类号： A61N105
CPC分类号： A61N1/0573 , A61N1/0563
摘要： A single-pass endocardial lead electrode adapted for implantation in, on or about the heart and for connection to a system for monitoring or stimulating cardiac activity includes a lead body which is adapted for implantation within a single chamber of the heart, or multiple chambers of the heart. The lead includes a first distal end electrode which has a first electrical conducting surface. The lead body also has a second electrode which has a second electrical conducting surface. The first and second electrodes are either passively or actively attached to the wall of the heart. The lead body also includes a curved portion which facilitates the positioning of the second electrode. The main lead body alternatively includes a recess into which an atrial lead body and an active fixation element attached to one end can travel from a recessed position to a position for fixation to the wall of the heart. The active fixation element can also be moved by turning the terminal pin. The lead body can also include multiple legs, each leg carrying an electrode. The lead is attached to a pulse generator for producing pulses to the multiple sites within the heart. A movement assembly for advancing a helix is also included within the legs and comprises an externally threaded collar which engages with an internally threaded housing or housing insert. The lead further includes a helical tip which has high impedance. The electrode has at least one features of the group: the helix having a coating of an insulating material on its surface, the helix having its surface beyond the distal end of the electrode and the distal end of the electrode having a porous conductive surface at a base of the helix, a porous conductive element at a base of the helix, and a porous conductive element at the end of the electrode having an insulating coating cover from 5-95% of the surface of the porous conductive element. The porous element may further provide a guiding mechanism for the helix as it travels out of the electrode for securing the electrode to the heart.

2. 发明授权

US06505082B1 Single pass lead system 失效
公开(公告)号：US06505082B1
公开(公告)日：2003-01-07
申请号：US09643125
申请日：2000-08-21
申请人： Avram Scheiner , William Hsu , David M. Flynn , Qingsheng Zhu , John E. Heil , Ronald W. Heil, Jr. , Curtis C. Lindstrom , Robert S. Booker, III , Yayun Lin , Peter T. Kelley , Jay A. Warren , Gerrard M. Carlson , Carol Werlein , Aaron W. Janke , Mary Lee Cole , Jeffrey T. Bartig , Gary W Goebel , Douglas A Heitkamp , Randall M. Peterfeso
发明人： Avram Scheiner , William Hsu , David M. Flynn , Qingsheng Zhu , John E. Heil , Ronald W. Heil, Jr. , Curtis C. Lindstrom , Robert S. Booker, III , Yayun Lin , Peter T. Kelley , Jay A. Warren , Gerrard M. Carlson , Carol Werlein , Aaron W. Janke , Mary Lee Cole , Jeffrey T. Bartig , Gary W Goebel , Douglas A Heitkamp , Randall M. Peterfeso
IPC分类号： A61N105
CPC分类号： A61N1/0573 , A61N1/0563
摘要： A single-pass endocardial lead electrode adapted for implantation in, on or about the heart and for connection to a system for monitoring or stimulating cardiac activity includes a lead body which is adapted for implantation within a single chamber of the heart, or multiple chambers of the heart. The lead includes a first distal end electrode which has a first electrical conducting surface. The lead body also has a second electrode which has a second electrical conducting surface. The first and second electrodes are either passively or actively attached to the wall of the heart. The lead body also includes a curved portion which facilitates the positioning of the second electrode. The main lead body alternatively includes a recess into which an atrial lead body and an active fixation element attached to one end can travel from a recessed position to a position for fixation to the wall of the heart. The active fixation element can also be moved by turning the terminal pin. The lead body can also include multiple legs, each leg carrying an electrode. The lead is attached to a pulse generator for producing pulses to the multiple sites within the heart. A movement assembly for advancing a helix is also included within the legs and comprises an externally threaded collar which engages with an internally threaded housing or housing insert. The lead further includes a helical tip which has high impedance. The electrode has at least one features of the group: the helix having a coating of an insulating material on its surface, the helix having its surface beyond the distal end of the electrode and the distal end of the electrode having a porous conductive surface at a base of the helix, a porous conductive element at a base of the helix, and a porous conductive element at the end of the electrode having an insulating coating cover from 5-95% of the surface of the porous conductive element. The porous element may further provide a guiding mechanism for the helix as it travels out of the electrode for securing the electrode to the heart.

3. 发明授权

US06501994B1 High impedance electrode tip 失效
标题翻译：高阻抗电极尖端
公开(公告)号：US06501994B1
公开(公告)日：2002-12-31
申请号：US09121288
申请日：1998-07-22
申请人： Aaron W. Janke , Mary Lee Cole , Ronald W. Heil, Jr. , Jeffrey T. Bartig , Gary W Goebel , Douglas A Heitkamp , Randall M. Peterfeso
发明人： Aaron W. Janke , Mary Lee Cole , Ronald W. Heil, Jr. , Jeffrey T. Bartig , Gary W Goebel , Douglas A Heitkamp , Randall M. Peterfeso
IPC分类号： A61N105
CPC分类号： A61N1/0573
摘要： An implantable lead, being either a fixed or retractable/extendable lead, having a distal tip electrode is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The electrode includes a mechanical fastener such as a fixation helix for securing the electrode to cardiac tissue, which may or may not be electrically active. The implantable electrode with a helical tip includes an electrode which has a distal end and a proximal end. A helix is disposed within the electrode, where the helix is aligned along a radial axis of the electrode. The electrode further includes one or more of the following features: the helix having a coating of an insulating material on a surface of the helix, a porous conductive surface at a base of the helix, a porous conductive element at the end of the electrode having an insulating coating covering from 5-95% of the surface of the porous conductive element. The electrode may farther include an electrode tip having a porous electrical conductive element, such as a mesh screen, disposed on a surface at the distal end of the electrode tip, which can be used as a sensing or pacing interface with the cardiac tissue.
摘要翻译：具有远端尖端电极的可植入引线（或者是固定的或可伸缩的引线）适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。电极包括机械紧固件，例如用于将电极固定到心脏组织的固定螺旋，其可以是或不是电活动的。具有螺旋尖端的可植入电极包括具有远端和近端的电极。螺旋线设置在电极内，其中螺旋沿着电极的径向轴线排列。电极还包括以下特征中的一个或多个：螺旋具有在螺旋表面上的绝缘材料的涂层，在螺旋的基底处的多孔导电表面，在电极末端的多孔导电元件，覆盖多孔导电元件表面的5-95％的绝缘涂层。电极可以进一步包括具有设置在电极尖端的远端的表面上的多孔导电元件（例如网眼丝网）的电极末端，其可以用作与心脏组织的感测或起搏界面。

4. 发明授权

US06240321B1 Expandable seal for use with medical device and system 有权
标题翻译：用于医疗设备和系统的可扩展密封件
公开(公告)号：US06240321B1
公开(公告)日：2001-05-29
申请号：US09133310
申请日：1998-08-12
申请人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
发明人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
IPC分类号： A61N105
CPC分类号： A61N1/0573 , A61N1/0565
摘要： A seal adapted for use with medical devices is provided with a lead having a distal tip electrode. The distal tip of the lead is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead can include a fixation helix for securing the electrode to cardiac tissue. The lead assembly can alternatively include an open lumen lead tip. A seal is provided within the lead tip assembly such that the seal is expanded to prevent or limit further entry of fluids through the lead tip. The seal includes an expandable matrix, such as a hydrogel. The seal is formed on or within the lead when the lead and the seal comes into contact with a fluid and expands. The seal is also formed as a plug which is deployed through the medical device, and expands as the plug absorbs fluid. A housing incorporating the seal can also be attached to a portion of the medical device to provide the seal.
摘要翻译：适于与医疗装置一起使用的密封件设置有具有远端尖端电极的引线。引线的远端适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。引线可以包括用于将电极固定到心脏组织的固定螺旋。导线组件可以替代地包括开放的管腔引线端头。在引线端头组件内设置密封件，使得密封件被膨胀以防止或限制流体进一步通过引线头进入。密封件包括可膨胀基质，例如水凝胶。当铅和密封件与流体接触并膨胀时，密封件形成在引线上或内部。密封件还形成为通过医疗装置展开的塞子，并且当塞子吸收流体时膨胀。结合密封件的壳体也可以附接到医疗装置的一部分以提供密封。

5. 发明授权

US06901288B2 Sealing assembly for intravenous lead 有权
标题翻译：密封组件用于静脉引导
公开(公告)号：US06901288B2
公开(公告)日：2005-05-31
申请号：US09970195
申请日：2001-10-02
申请人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
发明人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
IPC分类号： A61N1/05 , A61N1/362
CPC分类号： A61N1/0573 , A61N1/0565
摘要： A seal adapted for use with medical devices is provided with a lead having a distal tip electrode. The distal tip of the lead is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead can include a fixation helix for securing the electrode to cardiac tissue. The lead assembly can alternatively include an open lumen lead tip. A seal is provided within the lead tip assembly such that the seal is expanded to prevent or limit further entry of fluids through the lead tip. The seal includes an expandable matrix, such as a hydrogel. The seal is formed on or within the lead when the lead and the seal comes into contact with a fluid and expands. The seal is also formed as a plug which is deployed through the medical device, and expands as the plug absorbs fluid. A housing incorporating the seal can also be attached to a portion of the medical device to provide the seal.
摘要翻译：适于与医疗装置一起使用的密封件设置有具有远端尖端电极的引线。引线的远端适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。引线可以包括用于将电极固定到心脏组织的固定螺旋。导线组件可以替代地包括开放的管腔引线端头。在引线端头组件内设置密封件，使得密封件被膨胀以防止或限制流体进一步通过引线头进入。密封件包括可膨胀基质，例如水凝胶。当铅和密封件与流体接触并膨胀时，密封件形成在引线上或内部。密封件还形成为通过医疗装置展开的塞子，并且当塞子吸收流体时膨胀。结合密封件的壳体也可以附接到医疗装置的一部分以提供密封。

6. 发明授权

US07412290B2 Seal for use with medical device and system 失效
标题翻译：用于医疗器械和系统的密封
公开(公告)号：US07412290B2
公开(公告)日：2008-08-12
申请号：US10968305
申请日：2004-10-20
申请人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
发明人： Aaron W. Janke , Larry L. Hum , Randy Westlund , Ronald W. Heil, Jr. , Bruce Tockman
IPC分类号： A61N1/372
CPC分类号： A61N1/0573 , A61N1/0565
摘要： A seal adapted for use with medical devices is provided with a lead having a distal tip electrode. The distal tip of the lead is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead can include a fixation helix for securing the electrode to cardiac tissue. The lead assembly can alternatively include an open lumen lead tip. A seal is provided within the lead tip assembly such that the seal is expanded to prevent or limit further entry of fluids through the lead tip. The seal includes an expandable matrix, such as a hydrogel. The seal is formed on or within the lead when the lead and the seal comes into contact with a fluid and expands. The seal is also formed as a plug which is deployed through the medical device, and expands as the plug absorbs fluid. A housing incorporating the seal can also be attached to a portion of the medical device to provide the seal.
摘要翻译：适于与医疗装置一起使用的密封件设置有具有远端尖端电极的引线。引线的远端适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。引线可以包括用于将电极固定到心脏组织的固定螺旋。导线组件可以替代地包括开放的管腔引线端头。在引线端头组件内设置密封件，使得密封件被膨胀以防止或限制流体进一步通过引线头进入。密封件包括可膨胀基质，例如水凝胶。当铅和密封件与流体接触并膨胀时，密封件形成在引线上或内部。密封件还形成为通过医疗装置展开的塞子，并且当塞子吸收流体时膨胀。结合密封件的壳体也可以附接到医疗装置的一部分以提供密封。

7. 发明授权

US6097986A Retractable lead with mesh screen 失效
标题翻译：带网眼的伸缩线
公开(公告)号：US6097986A
公开(公告)日：2000-08-01
申请号：US992039
申请日：1997-12-17
申请人： Aaron W. Janke , Mary Lee Cole
发明人： Aaron W. Janke , Mary Lee Cole
IPC分类号： A61N1/05
CPC分类号： A61N1/0573
摘要： A retractable lead having a distal tip electrode is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The electrode includes a fixation helix for securing the electrode to cardiac tissue, which may or may not be electrically active. The electrode further includes an electrode tip having a mesh screen disposed on a surface at the distal end of the electrode tip, which can be used as a sensing or pacing interface with the cardiac tissue. The mesh screen provides a guiding mechanism for the helix as it travels out of the electrode for securing the electrode to the heart or other muscle or organ. The guiding mechanism may include a groove within the mesh screen. Alternatively, the guiding mechanism includes a guiding bar on which the fixation helix rides on during extension or retraction.
摘要翻译：具有远端尖端电极的可伸缩引线适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。电极包括用于将电极固定到心脏组织的固定螺旋，其可以是或不是电活动的。电极还包括具有设置在电极末端的远端的表面上的网眼的电极末端，其可以用作与心脏组织的感测或起搏界面。网状筛网提供了一种用于螺旋线的导引机构，因为其行进出电极以将电极固定到心脏或其他肌肉或器官。引导机构可以包括网筛内的凹槽。或者，引导机构包括引导杆，其中固定螺旋在延伸或缩回期间骑行。

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